A prospective evaluation of the Infection Probability Score (IPS) in the intensive care unit

Journal of Infection

Volumn 56, Issue 5, 2008, Pages 313-318

  Martini, Alvise ^a   Gottin, Leonardo ^a   Mélot, Christian ^b   Vincent, Jean Louis ^b  

^a UNIVERSITY OF VERONA   (Italy)

^b ERASME HOSPITAL   (Belgium)

Author keywords

Antimicrobial therapy; C reactive protein; Infection; Outcome

Indexed keywords

ANTIBIOTIC AGENT; ANTIINFECTIVE AGENT;

ACUTE DISEASE; ADULT; AGED; ANTIBIOTIC THERAPY; ANTIMICROBIAL THERAPY; ARTICLE; CLINICAL STUDY; CONTROLLED STUDY; DIAGNOSTIC VALUE; DRUG EFFICACY; FEMALE; HOSPITAL ADMISSION; HOSPITAL INFECTION; HOSPITALIZATION; HUMAN; INFECTION PROBABILITY SCORE; INTENSIVE CARE UNIT; MAJOR CLINICAL STUDY; MALE; MICROBIOLOGICAL EXAMINATION; MORTALITY; OBSERVATIONAL STUDY; PREDICTION; PROBABILITY; PROSPECTIVE STUDY; SCORING SYSTEM;

ADULT; AGED; AGED, 80 AND OVER; ANTI-BACTERIAL AGENTS; BODY TEMPERATURE; C-REACTIVE PROTEIN; CRITICAL ILLNESS; CROSS INFECTION; FEMALE; HEART RATE; HUMANS; INTENSIVE CARE UNITS; LEUKOCYTE COUNT; MALE; MIDDLE AGED; MULTIPLE ORGAN FAILURE; SEVERITY OF ILLNESS INDEX;

EID: 42649114781     PISSN: 01634453     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jinf.2008.02.015     Document Type: Article

References (23)

1. Vincent J.L., Sakr Y., Sprung C.L., Ranieri V.M., Reinhart K., Gerlach H., et al. Sepsis in European intensive care units: results of the SOAP study. Crit Care Med 34 2 (2006) 344-353
2. Kollef M.H., Sherman G., Ward S., and Fraser V.J. Inadequate antimicrobial treatment of infections: a risk factor for hospital mortality among critically ill patients. Chest 115 2 (1999) 462-474
3. Smith T.L., Pearson M.L., Wilcox K.R., Cruz C., Lancaster M.V., Robinson-Dunn B., et al. Emergence of vancomycin resistance in Staphylococcus aureus. Glycopeptide-Intermediate Staphylococcus aureus Working Group. N Engl J Med 340 7 (1999) 493-501
4. Ariza J., Pujol M., Cabo J., Pena C., Fernandez N., Linares J., et al. Vancomycin in surgical infections due to methicillin-resistant Staphylococcus aureus with heterogeneous resistance to vancomycin. Lancet 353 9164 (1999) 1587-1588
5. Peres-Bota D., Melot C., Lopes Ferreira F., and Vincent J.L. Infection probability score (IPS): a simple method to help assess the probability of infection in critically patients. Crit Care Med 31 (2003) 2579-2584
6. Povoa P. C-reactive protein: a valuable marker of sepsis. Intensive Care Med 28 3 (2002) 235-243
7. Reny J.L., Vuagnat A., Ract C., Benoit M.O., Safar M., and Fagon J.Y. Diagnosis and follow-up of infections in intensive care patients: value of C-reactive protein compared with other clinical and biological variables. Crit Care Med 30 3 (2002) 529-535
8. Lobo S.M., Lobo F.R., Bota D.P., Lopes-Ferreira F., Soliman H.M., Melot C., et al. C-reactive protein levels correlate with mortality and organ failure in critically ill patients. Chest 123 6 (2003) 2043-2049
9. Gabay C., and Kushner I. Acute-phase proteins and other systemic responses to inflammation. N Engl J Med 340 6 (1999) 448-454
10. Luzzani A., Polati E., Dorizzi R., Rungatscher A., Pavan R., and Merlini A. Comparison of procalcitonin and C-reactive protein as markers of sepsis. Crit Care Med 31 6 (2003) 1737-1741
11. BalcI C., Sungurtekin H., Gurses E., Sungurtekin U., and Kaptanoglu B. Usefulness of procalcitonin for diagnosis of sepsis in the intensive care unit. Crit Care 7 1 (2003) 85-90
12. Muller B., Becker K.L., Schachinger H., Rickenbacher P.R., Huber P.R., Zimmerli W., et al. Calcitonin precursors are reliable markers of sepsis in a medical intensive care unit. Crit Care Med 28 4 (2000) 977-983
13. Gattas D.J., and Cook D.J. Procalcitonin as a diagnostic test for sepsis: health technology assessment in the ICU. J Crit Care 18 1 (2003) 52-58
14. Vincent J.L., Moreno R., Takala J., Willatts S., de Mendonça A., Bruining H., et al. The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure. Intensive Care Med 22 (1996) 707-710
15. Garner J.S., Jarvis W.R., Emori T.G., Horan T.C., and Hughes J.M. CDC definitions for nosocomial infections, 1988. Am J Infect Control 16 3 (1989) 128-140
16. Pugin J., Auckenthaler R., Mili N., Janssens J.P., Lew P.D., and Suter P.M. Diagnosis of ventilator-associated pneumonia by bacteriologic analysis of bronchoscopic and nonbronchoscopic "blind" bronchoalveolar lavage fluid. Am Rev Respir Dis 143 5 Pt 1 (1991) 1121-1129
17. Harbarth S., Garbino J., Pugin J., Romand J.A., Lew D., and Pittet D. Inappropriate initial antimicrobial therapy and its effect on survival in a clinical trial of immunomodulating therapy for severe sepsis. Am J Med 115 7 (2003) 529-535
18. Schramm G.E., Johnson J.A., Doherty J.A., Micek S.T., and Kollef M.H. Methicillin-resistant Staphylococcus aureus sterile-site infection: the importance of appropriate initial antimicrobial treatment. Crit Care Med 34 8 (2006) 2069-2074
19. Zaragoza R., Artero A., Camarena J.J., Sancho S., Gonzalez R., and Nogueira J.M. The influence of inadequate empirical antimicrobial treatment on patients with bloodstream infections in an intensive care unit. Clin Microbiol Infect 9 5 (2003) 412-418
20. Luna C.M., Aruj P., Niederman M.S., Violi D., Prignoni A., Rios F., et al. Appropriateness and delay to initiate therapy in ventilator-associated pneumonia. Eur Respir J 27 1 (2006) 158-164
21. Ibrahim E.H., Sherman G., Ward S., Fraser V.J., and Kollef M.H. The influence of inadequate antimicrobial treatment of bloodstream infections on patient outcomes in the ICU setting. Chest 118 1 (2000) 146-155
22. Christ-Crain M., Stolz D., Bingisser R., Muller C., Miedinger D., Huber P.R., et al. Procalcitonin-guidance of antibiotic therapy in community-acquired pneumonia: a randomized trial. Am J Respir Crit Care Med 174 (2006) 84-93
23. Christ-Crain M., Jaccard-Stolz D., Bingisser R., Gencay M.M., Huber P.R., Tamm M., et al. Effect of procalcitonin-guided treatment on antibiotic use and outcome in lower respiratory tract infections: cluster-randomised, single-blinded intervention trial. Lancet 363 9409 (2004) 600-607