High-amylose sodium carboxymethyl starch matrices for oral, sustained drug-release: Formulation aspects and in vitro drug-release evaluation

International Journal of Pharmaceutics

Volumn 356, Issue 1-2, 2008, Pages 52-60

  Brouillet, F ^a,b   Bataille, B ^b   Cartilier, L ^a  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

^b UNIV MONTPELLIER   (France)

Author keywords

Amylose; Drug delivery; Excipient; In vitro; Matrix; Polymer; Starch; Sustained release; Tablet

Indexed keywords

ELECTROLYTE; HIGH AMYLOSE SODIUM CARBOXYMETHYL STARCH; PARACETAMOL; SODIUM CHLORIDE; STARCH;

ARTICLE; COMPRESSION; DRUG DIFFUSION; DRUG FORMULATION; DRUG RELEASE; IN VITRO STUDY; PARTICLE SIZE; PRIORITY JOURNAL; SPRAY DRYING; SURFACE PROPERTY; TABLET FORMULATION;

ACETAMINOPHEN; ADMINISTRATION, ORAL; CHEMISTRY, PHARMACEUTICAL; DELAYED-ACTION PREPARATIONS; DRUG CARRIERS; EXCIPIENTS; PARTICLE SIZE; SODIUM CHLORIDE; STARCH; TABLETS; TECHNOLOGY, PHARMACEUTICAL; TIME FACTORS;

EID: 42649092866     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2007.12.039     Document Type: Article

References (20)

1. Bilariedis C.G. The structure and interactions of starch with food constituents. Can. J. Physiol. Pharmacol. 69 (1991) 60-78
2. Brouillet F., Bataille B., Baylac G. and Cartilier L., 2007. High-amylose sodium carboxymethyl starch sustained release excipient and process for preparing the same. Canadian Patent Application No. 2,590,821, June 7.
3. Cartilier L., Ungur M., Chebli C., 2005. Tablet formulation for sustained drug-release. Canadian Patent Application No. 2,491,665, December 24, 2004; PCT Application No. PCT/CA2005/001934, December 20.
4. Cartilier L., Moussa I., Chebli C. and Buczkowski S., 1999. Substituted amylose as a matrix for sustained drug release. U.S. Patent No. 5,879,707.
5. Chebli C., and Cartilier L. Effect of some physical parameters on the sustained-drug release properties of substituted amylose matrices. Int. J. Pharm. 193 (2000) 167-173
6. Chebli C., Moussa I., Buczkowski S., and Cartilier L. Substituted amylose as a matrix for sustained drug release. Pharm. Res. 16 (1999) 1436-1440
7. Domingues Nabais T., Brouillet F., Kyriacos S., Mroueh M., Amores da Silva P., Bataille B., Chebli C., and Cartilier L. High-amylose carboxymethyl starch matrices for oral sustained drug-release: in vitro and in vivo evaluation. Eur. J. Biopharm. Pharm. 65 (2007) 371-378
8. Ford J.L., Rubinstein M.H., McCaul F., Hogan J.E., and Edgar P.J. Importance of drug type, tablet shape and added diluents on release kinetics from hydroxypropyl methylcellulose matrix tablets. Int. J. Pharm. 40 (1987) 233-234
9. Ingani H., and Moës A. Utilisation de la gomme xanthane dans la formulation des matrices hydrophiles. Proceedings of the 4th International Conference on Pharmaceutical Technology. APGI, Paris, June (1986) 272-281
10. Kuhrts E.H., 1992. Prolonged release drug tablet formulations. U.S. Patent 5,096,714.
11. Levina M. Influence of fillers, compression force, film coatings and storage conditions on performance of hypromellose matrices. Drug Deliv. Technol. 4 1 (2004) January/February
12. Moghadam S.H., Wang H.W., El-Leithy E.H., Chebli C., and Cartilier L. Substituted amylose matrices for oral drug delivery. Biomed. Mater. 2 (2007) S71-S77
13. Peppas N.A. Analysis of Fickian and non-Fickian drug release from polymers. Pharm. Acta Helv. 60 (1985) 110-111
14. Peppas N.A., and Sahlin J.J. A simple equation for the description of solute release. III: Coupling of diffusion and relaxation. Int. J. Pharm. 57 (1989) 169-172
15. Salomon J.-L., Vuagnat P., Doelker E., and Buri P. Influence de la force de compression, de la granulométrie du traceur et de l'épaisseur du comprimé. Pharm. Acta Helv. 54 (1979) 86-89
16. Sinclair G.W., and Peppas N.A. Analysis of non-Fickian transport in polymers using a simplified exponential expression. J. Membr. Sci. 17 (1984) 329-331
17. Ungur M., Yonis N., Chebli C., and Cartilier L. The evaluation of carboxymethylamylose for oral drug delivery systems: from laboratory to pilot scale. Proceedings of ISAB 2005 Abstracts of the 3rd International Symposium on Advanced Biomaterials/Biomechanics. Montreal, Canada, April 3-6 (2005) 271
18. Varma M.V.S., Kaushal A.M., Garg A., and Garg S. Factors affecting the mechanism and kinetics of drug release from matrix-based oral controlled drug delivery systems. Am. J. Drug Deliv. 2 (2004) 43-57
19. Velasco M.V., Ford J.L., Rowe P., and Rajabi-Siahboomi A.R. Influence of drug: hydroxypropylmethylcellulose ratio, drug and polymer particle size and compression force on the release of diclofenac sodium from HPMC tablets. J. Contr. Rel. 57 (1999) 75-85
20. Wang H.W., 2006. Développement et évaluation de comprimés enrobés à sec, à base d'amylose substitué, Mémoire M.Sc., Faculté de pharmacie, Université de Montréal, August.