Glycerol and bacterial meningitis: A response to the editorial commentary by Sáez-Llorens and McCracken

Clinical Infectious Diseases

Volumn 46, Issue 7, 2008, Pages 1123-1124

  Peltola, Heikki ^a   Roine, Irmeli ^b  

^a HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^b UNIVERSIDAD DIEGO PORTALES   (Chile)

Author keywords

[No Author keywords available]

Indexed keywords

CEFUROXIME; DEXAMETHASONE; GLYCEROL;

BACTERIAL MENINGITIS; EVOKED BRAIN STEM RESPONSE; HAEMOPHILUS INFLUENZAE TYPE B; HUMAN; LETTER; MEDICAL ETHICS; PRIORITY JOURNAL; TREATMENT RESPONSE;

CHILD; CHILD, PRESCHOOL; DEXAMETHASONE; GLYCEROL; HUMANS; MENINGITIS, BACTERIAL;

EID: 42549157685     PISSN: 10584838     EISSN: None     Source Type: Journal    
DOI: 10.1086/529389     Document Type: Letter

References (7)

1. Peltola H, Roine I, Fernández J, et al. Adjuvant glycerol and/or dexamethasone to improve the outcomes of childhood bacterial meningitis: a prospective, randomized, double-blind, placebo-controlled trial. Clin Infect Dis 2007; 45:1277-86.
2. Sáez-Llorens X, McCracken GH, Jr. Glycerol and bacterial meningitis. Clin Infect Dis 2007; 45:1287-9.
3. Lebel MH, Freij BJ, Syrogiannopoulos GA, et al. Dexamethasone therapy for bacterial meningitis: results of two double-blind, placebo-controlled trials. N Engl J Med 1988; 319:964-71.
4. Dexamethasone therapy for bacterial meningitis. N Engl J Med 1989; 320:463-5.
5. Roine I, Peltola H, Fernández J, et al. Influence of admission findings on death and neurological outcome from childhood bacterial meningitis. Clin Infect Dis (in press).
6. Molyneux EM, Walsh AL, Forsyth H, et al. Dexamethasone treatment in childhood bacterial meningitis in Malawi: a randomised controlled trial. Lancet 2002; 360:211-8.
7. Singhi S, Järvinen A, Peltola H. Increase in serum osmolality is possible mechanism for the beneficial effects of glycerol in childhood bacterial meningitis. Pediatr Infect Dis J (in press).