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Volumn 28, Issue 2 A, 2008, Pages 577-581

A new micronized formulation of 2-methoxyestradiol-bis-sulfamate (STX140) is therapeutically potent against breast cancer

Author keywords

2 methoxyestradiol; Breast cancer; Estrogen; STX140; Sulfamate

Indexed keywords

2 METHOXYESTRADIOL 3,17 O,O BIS SULFAMATE; ESTROGEN DERIVATIVE; METHYLCELLULOSE; PROPYLENE GLYCOL; SODIUM CHLORIDE; STX 140; TETRAHYDROFURAN; UNCLASSIFIED DRUG;

EID: 42549154737     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (15)

References (16)
  • 2
    • 0031015504 scopus 로고    scopus 로고
    • Inhibition of angiogenesis and breast cancer in mice by the microtubule inhibitors 2-methoxyestradiol and taxol
    • Klauber N, Parangi S, Flynn E, Hamel E and D'Amato RJ: Inhibition of angiogenesis and breast cancer in mice by the microtubule inhibitors 2-methoxyestradiol and taxol. Cancer Res 57: 81-86, 1997.
    • (1997) Cancer Res , vol.57 , pp. 81-86
    • Klauber, N.1    Parangi, S.2    Flynn, E.3    Hamel, E.4    D'Amato, R.J.5
  • 3
    • 32544433479 scopus 로고    scopus 로고
    • Dahut WL, Lakhani NJ, Gulley JL, Arlen PM, Kohn EC, Kotz H, McNally D, Parr A, Nquyen D, Yang SX, Steinberg SM, Ventiz, Sparreboom A and Figg WD: Phase I clinical trial of oral 2-methoxyestradiol, an antiangiogenic and apoptotic agent, in patients with solid tumors. Cancer Biol Ther 5: 22-27, 2006.
    • Dahut WL, Lakhani NJ, Gulley JL, Arlen PM, Kohn EC, Kotz H, McNally D, Parr A, Nquyen D, Yang SX, Steinberg SM, Ventiz, Sparreboom A and Figg WD: Phase I clinical trial of oral 2-methoxyestradiol, an antiangiogenic and apoptotic agent, in patients with solid tumors. Cancer Biol Ther 5: 22-27, 2006.
  • 6
    • 0034307330 scopus 로고    scopus 로고
    • Differential effects of estrone and estrone-3-O-sulfamate derivatives on mitotic arrest, apoptosis, and microtubule assembly in human breast cancer cells
    • MacCarthy-Morrogh L, Townsend PA, Purohit A, Hejaz HAM, Potter BVL, Reed MJ and Packham G: Differential effects of estrone and estrone-3-O-sulfamate derivatives on mitotic arrest, apoptosis, and microtubule assembly in human breast cancer cells. Cancer Res 60: 5441-5450, 2000.
    • (2000) Cancer Res , vol.60 , pp. 5441-5450
    • MacCarthy-Morrogh, L.1    Townsend, P.A.2    Purohit, A.3    Hejaz, H.A.M.4    Potter, B.V.L.5    Reed, M.J.6    Packham, G.7
  • 7
    • 24344456018 scopus 로고    scopus 로고
    • Inhibition of MDA-MB-231 cell cycle progression and cell proliferation by C-2-substituted oestradiol mono- and bis-3-O-sulphamates
    • Raobaikady B, Reed MJ, Leese MP, Potter BVL and Purohit A: Inhibition of MDA-MB-231 cell cycle progression and cell proliferation by C-2-substituted oestradiol mono- and bis-3-O-sulphamates. Int J Cancer 117: 150-159, 2005.
    • (2005) Int J Cancer , vol.117 , pp. 150-159
    • Raobaikady, B.1    Reed, M.J.2    Leese, M.P.3    Potter, B.V.L.4    Purohit, A.5
  • 13
    • 0029114308 scopus 로고
    • Inactivation of steroid sulfatase by an active site-directed inhibitor, estrone-3-O-sulfamate
    • Purohit A, Williams GJ, Howarth NM, Potter BVL and Reed MJ: Inactivation of steroid sulfatase by an active site-directed inhibitor, estrone-3-O-sulfamate. Biochemistry 34: 11508-11514, 1995.
    • (1995) Biochemistry , vol.34 , pp. 11508-11514
    • Purohit, A.1    Williams, G.J.2    Howarth, N.M.3    Potter, B.V.L.4    Reed, M.J.5
  • 16
    • 10644273849 scopus 로고    scopus 로고
    • Effect of hydroxypropyl methylcellulose and hydrogenated castor oil on naproxen release from sustained-release tablets
    • Amaral MH, Lobo JM and Ferreira DC: Effect of hydroxypropyl methylcellulose and hydrogenated castor oil on naproxen release from sustained-release tablets. AAPS PharmSciTech 2: E6, 2001.
    • (2001) AAPS PharmSciTech , vol.2
    • Amaral, M.H.1    Lobo, J.M.2    Ferreira, D.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.