-
2
-
-
0031015504
-
Inhibition of angiogenesis and breast cancer in mice by the microtubule inhibitors 2-methoxyestradiol and taxol
-
Klauber N, Parangi S, Flynn E, Hamel E and D'Amato RJ: Inhibition of angiogenesis and breast cancer in mice by the microtubule inhibitors 2-methoxyestradiol and taxol. Cancer Res 57: 81-86, 1997.
-
(1997)
Cancer Res
, vol.57
, pp. 81-86
-
-
Klauber, N.1
Parangi, S.2
Flynn, E.3
Hamel, E.4
D'Amato, R.J.5
-
3
-
-
32544433479
-
-
Dahut WL, Lakhani NJ, Gulley JL, Arlen PM, Kohn EC, Kotz H, McNally D, Parr A, Nquyen D, Yang SX, Steinberg SM, Ventiz, Sparreboom A and Figg WD: Phase I clinical trial of oral 2-methoxyestradiol, an antiangiogenic and apoptotic agent, in patients with solid tumors. Cancer Biol Ther 5: 22-27, 2006.
-
Dahut WL, Lakhani NJ, Gulley JL, Arlen PM, Kohn EC, Kotz H, McNally D, Parr A, Nquyen D, Yang SX, Steinberg SM, Ventiz, Sparreboom A and Figg WD: Phase I clinical trial of oral 2-methoxyestradiol, an antiangiogenic and apoptotic agent, in patients with solid tumors. Cancer Biol Ther 5: 22-27, 2006.
-
-
-
-
4
-
-
31544434859
-
The role of 17β-hydroxysteroid dehydrogenases in modulating the activity of 2-methoxyestradiol in breast cancer cells
-
Newman SP, Ireson CR, Tutill HJ, Day JM, Parsons MF, Leese MP, Potter BVL, Reed MJ and Purohit A: The role of 17β-hydroxysteroid dehydrogenases in modulating the activity of 2-methoxyestradiol in breast cancer cells. Cancer Res 66: 324-330, 2006.
-
(2006)
Cancer Res
, vol.66
, pp. 324-330
-
-
Newman, S.P.1
Ireson, C.R.2
Tutill, H.J.3
Day, J.M.4
Parsons, M.F.5
Leese, M.P.6
Potter, B.V.L.7
Reed, M.J.8
Purohit, A.9
-
5
-
-
17944382588
-
17 beta-hydroxysteroid dehydrogenase type 2 expression and enzyme activity in the human gastrointestinal tract
-
Sano T, Hirasawa G, Takeyama J, Darnel AD, Suzuki T, Moriya T,Kato K, Sekine H, Ohara S, Shimoseqawa T, Nakamura J, Yoshihama M, Harada N and Sasano H: 17 beta-hydroxysteroid dehydrogenase type 2 expression and enzyme activity in the human gastrointestinal tract. Clin Sci (Lond) 101: 485-491, 2001.
-
(2001)
Clin Sci (Lond)
, vol.101
, pp. 485-491
-
-
Sano, T.1
Hirasawa, G.2
Takeyama, J.3
Darnel, A.D.4
Suzuki, T.5
Moriya, T.6
Kato, K.7
Sekine, H.8
Ohara, S.9
Shimoseqawa, T.10
Nakamura, J.11
Yoshihama, M.12
Harada, N.13
Sasano, H.14
-
6
-
-
0034307330
-
Differential effects of estrone and estrone-3-O-sulfamate derivatives on mitotic arrest, apoptosis, and microtubule assembly in human breast cancer cells
-
MacCarthy-Morrogh L, Townsend PA, Purohit A, Hejaz HAM, Potter BVL, Reed MJ and Packham G: Differential effects of estrone and estrone-3-O-sulfamate derivatives on mitotic arrest, apoptosis, and microtubule assembly in human breast cancer cells. Cancer Res 60: 5441-5450, 2000.
-
(2000)
Cancer Res
, vol.60
, pp. 5441-5450
-
-
MacCarthy-Morrogh, L.1
Townsend, P.A.2
Purohit, A.3
Hejaz, H.A.M.4
Potter, B.V.L.5
Reed, M.J.6
Packham, G.7
-
7
-
-
24344456018
-
Inhibition of MDA-MB-231 cell cycle progression and cell proliferation by C-2-substituted oestradiol mono- and bis-3-O-sulphamates
-
Raobaikady B, Reed MJ, Leese MP, Potter BVL and Purohit A: Inhibition of MDA-MB-231 cell cycle progression and cell proliferation by C-2-substituted oestradiol mono- and bis-3-O-sulphamates. Int J Cancer 117: 150-159, 2005.
-
(2005)
Int J Cancer
, vol.117
, pp. 150-159
-
-
Raobaikady, B.1
Reed, M.J.2
Leese, M.P.3
Potter, B.V.L.4
Purohit, A.5
-
8
-
-
48149110838
-
2-MeOE2bisMATE and 2-EtE2bisMATE induce cell cycle arrest and apoptosis in breast cancer xenografts as shown by a novel ex vivo technique
-
in press
-
Foster PA, Ho YT, Newman SP, Kasprzyk PG, Leese MP, Potter BVL, Reed MJ and Purohit A: 2-MeOE2bisMATE and 2-EtE2bisMATE induce cell cycle arrest and apoptosis in breast cancer xenografts as shown by a novel ex vivo technique. Breast Cancer Res Treat, in press, 2007.
-
(2007)
Breast Cancer Res Treat
-
-
Foster, P.A.1
Ho, Y.T.2
Newman, S.P.3
Kasprzyk, P.G.4
Leese, M.P.5
Potter, B.V.L.6
Reed, M.J.7
Purohit, A.8
-
9
-
-
1542510122
-
Inhibition of in vitro angiogenesis by 2-methoxy- and 2-ethyl-estrogen sulfamates
-
Newman SP, Leese MP, Purohit A, James DR, Rennie CE, Potter BVL and Reed MJ: Inhibition of in vitro angiogenesis by 2-methoxy- and 2-ethyl-estrogen sulfamates. Int J Cancer 109: 533-540, 2004.
-
(2004)
Int J Cancer
, vol.109
, pp. 533-540
-
-
Newman, S.P.1
Leese, M.P.2
Purohit, A.3
James, D.R.4
Rennie, C.E.5
Potter, B.V.L.6
Reed, M.J.7
-
10
-
-
0033956376
-
The effect of 2-methoxyoestrone-3-O-sulphamate on the growth of breast cancer cells and induced mammary tumours
-
Purohit A, Hejaz HA, Walden L, MacCarthy-Morrogh L, Packham G, Potter BVL and Reed MJ: The effect of 2-methoxyoestrone-3-O-sulphamate on the growth of breast cancer cells and induced mammary tumours. Int J Cancer 85: 584-589, 2000.
-
(2000)
Int J Cancer
, vol.85
, pp. 584-589
-
-
Purohit, A.1
Hejaz, H.A.2
Walden, L.3
MacCarthy-Morrogh, L.4
Packham, G.5
Potter, B.V.L.6
Reed, M.J.7
-
11
-
-
0037321660
-
The effects of 2-substituted oestrogen sulphamates on the growth of prostate and ovarian cancer cells
-
Day JM, Newman SP, Comninos A, Solomon C, Purohit A, Leese MP, Potter BVL and Reed MJ: The effects of 2-substituted oestrogen sulphamates on the growth of prostate and ovarian cancer cells. J Steroid Biochem Mol Biol 84: 317-325, 2003.
-
(2003)
J Steroid Biochem Mol Biol
, vol.84
, pp. 317-325
-
-
Day, J.M.1
Newman, S.P.2
Comninos, A.3
Solomon, C.4
Purohit, A.5
Leese, M.P.6
Potter, B.V.L.7
Reed, M.J.8
-
12
-
-
1642319678
-
Pharmacokinetics and efficacy of 2-methoxyoestradiol and 2-methoxyoestradiol-bis-sulphamate in vivo in rodents
-
Ireson CR, Chander SK, Purohit A, Perera S, Newman SP, Parish D, Leese MP, Smith AC, Potter BVL and Reed MJ: Pharmacokinetics and efficacy of 2-methoxyoestradiol and 2-methoxyoestradiol-bis-sulphamate in vivo in rodents. Br J Cancer 90: 932-937, 2004.
-
(2004)
Br J Cancer
, vol.90
, pp. 932-937
-
-
Ireson, C.R.1
Chander, S.K.2
Purohit, A.3
Perera, S.4
Newman, S.P.5
Parish, D.6
Leese, M.P.7
Smith, A.C.8
Potter, B.V.L.9
Reed, M.J.10
-
13
-
-
0029114308
-
Inactivation of steroid sulfatase by an active site-directed inhibitor, estrone-3-O-sulfamate
-
Purohit A, Williams GJ, Howarth NM, Potter BVL and Reed MJ: Inactivation of steroid sulfatase by an active site-directed inhibitor, estrone-3-O-sulfamate. Biochemistry 34: 11508-11514, 1995.
-
(1995)
Biochemistry
, vol.34
, pp. 11508-11514
-
-
Purohit, A.1
Williams, G.J.2
Howarth, N.M.3
Potter, B.V.L.4
Reed, M.J.5
-
14
-
-
33845953699
-
2-substituted estradiol bis-sulfamates, multitargeted antitumor agents: Synthesis, in vitro SAR, protein crystallography, and in vivo activity
-
Leese MP, Leblond B, Smith A, Newman SP, Di Fiore A, De Simone G, Supuran CT, Purohit A, Reed MJ and Potter BVL: 2-substituted estradiol bis-sulfamates, multitargeted antitumor agents: synthesis, in vitro SAR, protein crystallography, and in vivo activity. J Med Chem 28: 7683-7696, 2006.
-
(2006)
J Med Chem
, vol.28
, pp. 7683-7696
-
-
Leese, M.P.1
Leblond, B.2
Smith, A.3
Newman, S.P.4
Di Fiore, A.5
De Simone, G.6
Supuran, C.T.7
Purohit, A.8
Reed, M.J.9
Potter, B.V.L.10
-
15
-
-
0030203364
-
Pharmacokinetics of oestrone-3-O-sulphamate
-
Hidalgo Aragones MI, Purohit A, Parish D, Sahm UG, Pouton CW, Potter BVL and Reed MJ: Pharmacokinetics of oestrone-3-O-sulphamate. J Steroid Biochem Mol Biol 58: 611-617, 1996.
-
(1996)
J Steroid Biochem Mol Biol
, vol.58
, pp. 611-617
-
-
Hidalgo Aragones, M.I.1
Purohit, A.2
Parish, D.3
Sahm, U.G.4
Pouton, C.W.5
Potter, B.V.L.6
Reed, M.J.7
-
16
-
-
10644273849
-
Effect of hydroxypropyl methylcellulose and hydrogenated castor oil on naproxen release from sustained-release tablets
-
Amaral MH, Lobo JM and Ferreira DC: Effect of hydroxypropyl methylcellulose and hydrogenated castor oil on naproxen release from sustained-release tablets. AAPS PharmSciTech 2: E6, 2001.
-
(2001)
AAPS PharmSciTech
, vol.2
-
-
Amaral, M.H.1
Lobo, J.M.2
Ferreira, D.C.3
|