PDGFRβ and HIF-1α inhibition with imatinib and radioimmunotherapy of experimental prostate cancer

Cancer Biology and Therapy

Volumn 6, Issue 11, 2007, Pages 1763-1772

  Kimura, Yu ^a   Inoue, Kotaro ^a   Abe, Michio ^b   Nearman, Jessica ^a   Baranowska Kortylewicz, Janina ^a,c  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b Public Central Hospital   (Japan)

^c NEBRASKA MEDICAL CENTER   (United States)

Author keywords

Hypoxia inducible factor 1 ; Imatinib; Insulin like growth factor 1; PC 3 xenografts; Platelet derived growth factor; Prostate cancer; Radioimmunotherapy

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA; IMATINIB; IODINE 131; MONOCLONAL ANTIBODY CC49 I 131; PLATELET DERIVED GROWTH FACTOR BB; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; RADIOPHARMACEUTICAL AGENT; SOMATOMEDIN C; VASCULOTROPIN; ANTINEOPLASTIC AGENT; HIF1A PROTEIN, MOUSE; PIPERAZINE DERIVATIVE; PLATELET DERIVED GROWTH FACTOR; PLATELET-DERIVED GROWTH FACTOR BB; PYRIMIDINE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIANGIOGENIC ACTIVITY; ARTICLE; CANCER IMMUNOTHERAPY; CANCER INHIBITION; CANCER RADIOTHERAPY; COMPARATIVE STUDY; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DOWN REGULATION; DRUG DISTRIBUTION; DRUG HALF LIFE; DRUG MECHANISM; DRUG TUMOR LEVEL; DRUG UPTAKE; INHIBITION KINETICS; MALE; MOUSE; MULTIPLE CYCLE TREATMENT; NONHUMAN; PROSTATE ADENOCARCINOMA; PROSTATE CANCER; PROTEIN EXPRESSION; PROTEIN FUNCTION; RADIOIMMUNOTHERAPY; RADIOSENSITIVITY; REGULATORY MECHANISM; SINGLE DRUG DOSE; TISSUE PRESSURE; TREATMENT RESPONSE; TUMOR GROWTH; TUMOR XENOGRAFT; ANIMAL; DOSE RESPONSE; DRUG ANTAGONISM; NUDE MOUSE; PATHOLOGY; PROSTATE TUMOR; TUMOR CELL LINE;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; DOSE-RESPONSE RELATIONSHIP, DRUG; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; INSULIN-LIKE GROWTH FACTOR I; MALE; MICE; MICE, NUDE; PIPERAZINES; PLATELET-DERIVED GROWTH FACTOR; PROSTATIC NEOPLASMS; PYRIMIDINES; RADIOIMMUNOTHERAPY; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR BETA;

EID: 42549126860     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.6.11.4854     Document Type: Article

References (75)