Synthesis of some new quinazolin-4-one derivatives and evaluation of their antimicrobial and antiinflammatory effects

Acta Poloniae Pharmaceutica - Drug Research

Volumn 65, Issue 1, 2008, Pages 11-20

  Fathalla, Omar Abd El Fattah M ^a   Kassem, Emad M M ^a   Ibrahem, Neama M ^a   Kamel, Mohsen M ^a  

^a NATIONAL RESEARCH CENTRE   (Egypt)

Author keywords

2 ((E) 2 furan 2 yl vinyl) quinazolin 4(3H) one derivatives; Anti inflammatory activity; Antimicrobial activity

Indexed keywords

2 (2 FURAN 2 YLVINYL) 3 [4 (3 THIOPHEN 2 YLACRYLOYL)PHENYL] 3H QUINAZOLIN 4 ONE; 2 (2 FURAN 2 YLVINYL) 3 [4 [3 (4 HYDROXYPHENYL)ACRYLOYL]PHENYL] 3H QUINAZOLIN 4 ONE; 2 (2 FURAN 2 YLVINYL) 3 [4 [3 (4 METHOXYPHENYL)ACRYLOYL]PHENYL] 3H QUINAZOLIN 4 ONE; 2 (2 FURAN 2 YLVINYL) 3 [4 [3 (4 PHENYL)ACRYLOYL]PHENYL] 3H QUINAZOLIN 4 ONE; 2 (2 FURAN 2 YLVINYL) 3 [4 [5 (4 DIMETHYLAMINOPHENYL) 4,5 DIHYDROISOXAZOL 3 YL]PHENYL] 3H QUINAZOLIN 4 ONE; 2 (2 FURAN 2 YLVINYL) 3 [4 [5 (4 METHOXYPHENYL) 4,5 DIHYDRO 1 PHENYLPYRAZOL 3 YL]PHENYL] 3H QUINAZOLIN 4 ONE; 2 (2 FURAN 2 YLVINYL) 3 [4 [5 (4 METHOXYPHENYL) 4,5 DIHYDRO 1H PYRAZOL 3 YL]PHENYL] 3H QUINAZOLIN 4 ONE; 2 (2 FURAN 2 YLVINYL) 3 [4 [5 (4 METHOXYPHENYL) 4,5 DIHYDROISOXAZOL 3 YL]PHENYL] 3H QUINAZOLIN 4 ONE; 2 (2 FURAN 2 YLVINYL)BENZO[D][1,3]OXAZINDE 4 ONE; 2 (2 FURAN 2 YLVINYL)QUINAZOLIN 4(3H) ONE DERIVATIVE; 3 (4 ACETYLPHENYL) 2 [2 (2 FURYL)VINYL] (3H) QUINAZOLIN 4 ONE; 3 [4 (OMEGA CHLOROPHENYLTHIOSEMICARBAZONE ALPHA ETHYL)PHENYL] 2 [2 (2 FURYL)VINYL] 3H QUINAZOLIN 4 ONE; 3 [4 (OMEGA CYCLOHEXYLTHIOSEMICARBAZONE ALPHA ETHYL)PHENYL] 2 [2 (2 FURYL)VINYL] 3H QUINAZOLIN 4 ONE; 3 [4 [1 [(3 BENZOYL 4 PHENYL 3H THIAZOL YLIDENE)HYDRAZONE]ETHYL]PHENYL] 2 [2 (2 FURAN 2 YLVINYL)] 3H QUINAZOLIN 4 ONE; 3 [4 [1 [[3 (4 CHLOROPHENYL) 4 PHENYL 3H THIAZOL YLIDENE]HYDRAZONE]ETHYL]PHENYL] 2 (2 FURAN 2 YLVINYL) 3H QUINAZOLIN 4 ONE; 3 [4 [3 (4 DIMETHYLAMINOPHENYL)ACRYLOYL]PHENYL] 2 (2 FURAN 2 YLVINYL) 3H QUINAZOLIN 4 ONE; 3 [4 [6 (4 DIMETHYLAMINOPHEYL) 2 OXO 1,2,5,6 TETRAHYDROPYRIMIDIN 4 YL]PHENYL] 2 (2 FURAN 2 YLVINYL) 3H QUINAZOLIN 4 ONE; 3 [4 [6 (4 DIMETHYLAMINOPHEYL) 2 THIOXO 1,2,5,6 TETRAHYDROPYRIMIDIN 4 YL]PHENYL] 2 (2 FURAN 2 YLVINYL) 3H QUINAZOLIN 4 ONE; 6 [4 [2 (2 FURAN 2 YLVINYL) 4 OXO 4H QUINAZOLIN 3 YL]PHENYL] 2 IMINO 4 HYDROXYPHENYL 1,2 DIHYDROPYRIDINE 3 CARBONITRILE; 6 [4 [2 (2 FURAN 2 YLVINYL) 4 OXO 4H QUINAZOLIN 3 YL]PHENYL] 2 IMINO 4 METHOXYPHENYL 1,2 DIHYDROPYRIDINE 3 CARBONITRILE; 6 [4 [2 (2 FURAN 2 YLVINYL) 4 OXO 4H QUINAZOLIN 3 YL]PHENYL] 2 IMINO 4 PHENYL 1,2 DIHYDROPYRIDINE 3 CARBONITRILE; 6 [4 [2 (2 FURAN 2 YLVINYL) 4 OXO 4H QUINAZOLIN 3 YL]PHENYL] 2 OXO 4 3,4,5 TRIMETHOXYPHENYL 1,2 DIHYDROPYRIDINE 3 CARBONITRILE; 6 [4 [2 (2 FURAN 2 YLVINYL) 4 OXO 4H QUINAZOLIN 3 YL]PHENYL] 2 OXO 4 HYDROXYPHENYL 1,2 DIHYDROPYRIDINE 3 CARBONITRILE; 6 [4 [2 (2 FURAN 2 YLVINYL) 4 OXO 4H QUINAZOLIN 3 YL]PHENYL] 2 OXO 4 METHOXYPHENYL 1,2 DIHYDROPYRIDINE 3 CARBONITRILE; 6 [4 [2 (2 FURAN 2 YLVINYL) 4 OXO 4H QUINAZOLIN 3 YL]PHENYL] 2 OXO 4 PHENYL 1,2 DIHYDROPYRIDINE 3 CARBONITRILE; INDOMETACIN; QUINAZOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIINFLAMMATORY ACTIVITY; ANTIMICROBIAL ACTIVITY; ARTICLE; ASPERGILLUS NIGER; CANDIDA ALBICANS; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; ESCHERICHIA COLI; INFRARED SPECTROSCOPY; ISOMERISM; MALE; NONHUMAN; PAW EDEMA; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; STAPHYLOCOCCUS AUREUS; THIN LAYER CHROMATOGRAPHY;

ANIMALS; ANTI-INFECTIVE AGENTS; ANTI-INFLAMMATORY AGENTS; INDOMETHACIN; MALE; MICROBIAL SENSITIVITY TESTS; QUINAZOLINES; RATS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 42549121088     PISSN: 00016837     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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