Systemic osteoprotegerin gene therapy restores tumor-induced bone loss in a therapeutic model of beast cancer bone metastasis

Molecular Therapy

Volumn 16, Issue 5, 2008, Pages 871-878

  Chanda, Diptiman ^a   Isayeva, Tatyana ^a   Kumar, Sanjay ^a   Siegal, Gene P ^a   Szafran, April A ^a   Zinn, Kurt R ^b   Reddy, Vishnu V B ^a   Ponnazhagan, Selvarangan ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b University of Alabama at Birmingham   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; FC RECEPTOR; GREEN FLUORESCENT PROTEIN; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPROTEGERIN; PARVOVIRUS VECTOR; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOLUMINESCENCE; BLOOD ANALYSIS; BONE INJURY; BONE METASTASIS; BONE REMODELING; BREAST CANCER; CALCIUM BLOOD LEVEL; CANCER GENE THERAPY; CANCER INHIBITION; CANCER MORTALITY; CANCER SURVIVAL; CONTROLLED STUDY; CORTICAL BONE; DRUG BLOOD LEVEL; FEMALE; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; HYPERCALCEMIA; LIVER TOXICITY; METASTASIS INHIBITION; MICRO-COMPUTED TOMOGRAPHY; MORBIDITY; MORPHOMETRICS; MOUSE; NONHUMAN; OSTEOCLAST; OSTEOLYSIS; PROTEIN PROTEIN INTERACTION; SURVIVAL TIME; TRABECULAR BONE; TRANSGENE; TUMOR GROWTH; VIRAL GENE DELIVERY SYSTEM;

MUS;

EID: 42549118918     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/mt.2008.48     Document Type: Article

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