Lack of association among polymorphic xenobiotic-metabolizing enzyme genotypes and the occurrence and progression of oral carcinoma in a Brazilian population

Anticancer Research

Volumn 28, Issue 2 A, 2008, Pages 1023-1028

  Losi Guembarovski, Roberta ^a,b   Cólus, Ilce Mara De Syllos ^b   De Menezes, Rodrigo Paes ^b   Poliseli, Fernando ^b   Chaves, Vivian Nappi ^b   Kuasne, Hellen ^b   Leichsenring, Andrei ^a   Guembarovski, Alda Losi ^b   Oliveira, Benedito W ^d   Ramos, Gyl ^d   Cavalcanti, Teresa C S ^a,d   Mizuno, Lauro Toyshi ^c   Cavalli, Iglenir João ^a   Ribeiro, Enilze Maria De Souza Fonseca ^a,e  

^a FEDERAL UNIVERSITY OF PARANÁ   (Brazil)

^b STATE UNIVERSITY OF LONDRINA   (Brazil)

^c Centro Odontológico Norte do Paraná   (Brazil)

^d Hospital Erasto Gaertner   (Brazil)

^e Laboratório de Citogenética Humana e Oncogenética   (Brazil)

Author keywords

CYP1A1; GSTM1; GSTT1; Oral cancer; Susceptibility genes

Indexed keywords

CYTOCHROME P450 1A1; XENOBIOTIC AGENT;

ADULT; ARTICLE; BRAZIL; CANCER GROWTH; CANCER PATIENT; CANCER STAGING; CASE CONTROL STUDY; CONFIDENCE INTERVAL; ENZYME METABOLISM; ETHNICITY; FEMALE; GENETIC ANALYSIS; GENETIC POLYMORPHISM; GENETIC SUSCEPTIBILITY; GENOTYPE; HISTOPATHOLOGY; HUMAN; LYMPH NODE; MAJOR CLINICAL STUDY; MALE; MOUTH CARCINOMA; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SMOKING; SQUAMOUS CELL CARCINOMA; STATISTICAL SIGNIFICANCE; TUMOR DIFFERENTIATION; TUMOR VOLUME;

BRAZIL; CARCINOMA, SQUAMOUS CELL; CASE-CONTROL STUDIES; CELL DIFFERENTIATION; CYTOCHROME P-450 CYP1A1; DISEASE PROGRESSION; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; GLUTATHIONE TRANSFERASE; HUMANS; LINKAGE DISEQUILIBRIUM; MALE; MIDDLE AGED; MOUTH NEOPLASMS; NEOPLASM METASTASIS; POLYMORPHISM, GENETIC; XENOBIOTICS;

EID: 42549114751     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (34)

1. Zienolddiny S, Aguelon AM, Mironov N, Mathew B, Thomas G, Sankaranarayanan R and Yamasaki H: Genomic instability in oral squamous cell carcinoma: relationship to betel-quid chewing. Oral Oncol 40: 298-303, 2004.
2. Vecchia C, Lucchini F, Negri E and Levi F: Trends in oral cancer mortality in Europe. Oral Oncol 40: 433-439, 2004.
3. Scully C, Field JK and Tanzawa H: Genetic aberrations in oral or head and neck squamous cell carcinoma (SCCHN): 1. Carcinogen metabolism, DNA repair and cell cycle control. Oral Oncol 36: 256-263, 2000.
4. Vineis P, Veglia F, Anttila S, Benhamou S, Clapper ML, Dolzan V, Ryberg D, Hirvonen A, Kremers P, Le Marchand L, Pastorelli R, Rannug A, Romkes M, Schoket B, Strange RC, Garte S and Taioli E: CYP1A1, GSTM1 and GSTT1 polymorphisms and lung cancer: a pooled analysis of gene-gene interactions. Biomarkers 9: 298-305, 2004.
5. Sato M, Sato T, Izumo T and Amagasa T: Genetic polymorphism of drug-metabolizing enzymes and susceptibility to oral cancer. Carcinogenesis 20: 1927-1931, 1999.
6. Sato M, Sato T, Izumob T and Amagasa T: Genetically high susceptibility to oral squamous cell carcinoma in terms of combined genotyping of CYP1A1 and GSTM1 genes. Oral Oncol 36: 267-271, 2000.
7. Tanimoto K, Hayashi SI, Yoshiga K and Ichikawa T: Polymorphisms of the CYP1A1 and GSTM1 gene involved in oral squamous cell carcinoma in association with a cigarette dose. Oral Oncol 35: 191-196, 1999.
8. Hatagima A: Genetic polymorphisms and metabolism of endocrine disruptors in cancer susceptibility. Cad Saude Publica 18: 357-377, 2002.
9. Cascorbi I: Genetic basis of toxic reactions to drugs and chemicals. Toxicol Lett 162: 16-28, 2006.
10. Bartsch H, Rojas M, Nair U, Nair J and Alexandrov K: Genetic cancer susceptibility and DNA adducts: studies in smokers, tobacco chewers, and coke oven workers. Cancer Detect Prev 23: 445-453, 1999.
11. Alexandrov K, Cascorbi I, Rojas M, Bouvier G, Kriek E and Bartsch H: CYP1A1 and GSTM1 genotypes affect benzo[a]pyrene DNA adducts in smokers' lung: comparison with aromatic/hydrophobic adduct formation. Carcinogenesis 23: 1969-1977, 2002.
12. Nair UJ, Nair J, Mathew B and Bartsch H: Glutathione S-transferase M1 and T1 null genotypes as risk factors for oral leukoplakia in ethnic Indian betel quid/tobacco chewers. Carcinogenesis 20: 743-748, 1999.
13. Jourenkova-Mironova N, Voho A, Bouchardy, Wikman H, Dayer P, Benhamou S and Hirvonen A: Glutathione S-transferase GSTM3 and GSTP1 genotypes and larynx cancer risk. Cancer Epidemiol Biomarkers Prev 8: 185-188, 1999.
14. Buch CS, Notani PN and Bhisey RA: Polymorphism at GSTM1, GSTM3 and GSTT1 gene loci and susceptibility to oral cancer in an Indian population. Carcinogenesis 23: 803-807, 2002.
15. Drummond SN, Marco L, Noronha JCN and Gomez RS: GSTM1 polymorphism and oral squamous cell carcinoma. Oral Oncol 40: 52-55, 2004.
16. Miller SA, Dykes DD and Polesky HF: A simple salting out procedure for extraction DNA from human nucleated cell. Nucleic Acids Res 16: 1215, 1988.
17. Abdel-Rahman SZ, El-Zein RA, Anwar WA and Au WW: A multiplex PCR procedures for polymorphic analysis of GSTM1 and GSTT1 genes in population studies. Cancer Lett 107: 229-233, 1996.
18. Carstensen U, Alexandrie AK, Högstedt B, Rannug A, Bratt I and Hagmar L: B- and T-lymphocyte micronulei in chimney sweeps with respect to genetic polymorphism for CYP1A1 and GSTT1 (class Mu). Mutat Res 289: 187-195, 1993.
19. Knudsen LE, Loft SH and Autrup H: Risk assessment: the importance of genetic polymorphisms in man. Mutat Res 482: 83-88, 2001.
20. Idle JR: Is environmental carcinogenesis modulated by host polymorphism? Mutat Res 247: 259-266, 1991.
21. Nebert DW: Role of genetics and drug metabolism in human cancer risk. Mutat Res 247: 267-281, 1991.
22. Omenn GS: Future research directions in cancer ecogenetics. Mutat Res 247: 283-291, 1991.
23. Gattas GJ, de Carvalho MB, Siraque MS, Curioni OA, Kohler P, Eluf-Neto J and Wunsch-Filho V: Genetic polymorphisms of CYP1A1, CYP2E1, GSTM1 and GSTT1 associated with head and neck cancer. Head Neck 28: 819-826, 2006.
24. Leichsenring A, Losi-Guembarovski R, Maciel ME, Oliveira BW, Ramos G, Cavalcanti TCS, Bicalho MG, Cavalli IJ, Cólus IMS and Ribeiro EMF: CYP1A1 and GSTP1 polymorphisms in an oral cancer case-control study. Braz J Med Biol Res 39: 1569-1574, 2006.
25. Matthias C, Bockmuhl U, Jahnke V, Jones PW, Hayes JD, Alldersea J, Gilford J, Bailey L, Bath J, Worrall SF, Hand P, Fryer AA and Strange RC: Polymorphism in cytochrome P450 CYP2D6, CYP1A1, CYP2E1 and glutathione S-transferase, GSTM1, GSTM3, GSTT1 and susceptibility to tabaco-related cancers: studies in upper aerodigestive tract cancers. Pharmacogenetics 8: 91-100, 1998.
26. Gronau S, Koenig-Greger D, Jerg M and Riechelmann H: GSTM1 enzyme concentration and enzyme activity in correlation to the genotype of detoxification enzymes in squamous cell carcinoma of the oral cavity. Oral Dis 9: 62-67, 2003.
27. Hahn M, Hagedorn G, Kuhlisch E, Schackert HK and Eckelt U: Genetic polymorphisms of drug-metabolizing enzymes and susceptibility to oral cavity cancer. Oral Oncol 38: 486-490, 2002.
28. Marques CF, Koifman S, Koifman RJ, Boffetta P, Brennan P and Hatagima A: Influence of CYP1A1, CYP2E1, GSTM3 and NAT2 genetic polymorphisms in oral cancer susceptibility: results from a case control study in Rio de Janeiro. Oral Oncol 42: 632-637, 2006.
29. Naccarati A, Soucek P, Stetina R, Haufroid V, Kumar R, Vodickova L, Trtkova K, Dusinska M, Hemminki K and Vodicka P: Genetic polymorphisms and possible gene-gene interactions in metabolic and DNA repair genes: Effects on DNA damage. Mutat Res 593: 22-31, 2006.
30. Olshan AF, Weissler MC, Watson MA and Bell DA: GSTM1, GSTT1, GSTP1, CYP1A1, and NAT1 polymorphisms, tobacco use, and the risk of head and neck cancer. Cancer Epidemiol Biomarkers Prev 9: 185-191, 2000.
31. Hashibe M, Brennan P, Strange RC, Bhisey R, Cascorbi I, Lazarus P, Ophuis MBO, Benhamou S, Foulkes WD, Katoh T, Coutelle C, Romkes M, Gaspari L, Taioli E and Boffetta P: Meta- and pooled analyses of GSTM1, GSTT1, GSTP1, and CYP1A1. Genotypes and risk of head and neck cancer. Cancer Epidemiol Biomarkers Prev 12: 1509-1517, 2003.
32. Pharoah PDP, Dunning AM, Ponder BAJ and Easton DF: Association studies for finding cancer-susceptibility genetic variants. Nat Rev Cancer 4: 850-860, 2004.
33. Arruda VR, Grignolli CE, Gonçalves MS, Soares MC, Menezes R, Saad ST and Costa FF: Prevalence of homozygosity for the deleted alleles of glutathione S-transferase mu (GSTM1) and theta (GSTT1) among distinct ethnic groups from Brazil: relevance to environmental carcinogenesis? Clin Genet 54: 210-214, 1998.
34. Losi-Guembarovski R, D'Arce LPG and Cólus IMS: Glutathione S-transferase Mu (GSTM1) null genotype in relation to gender, age and smoking status in a healthy Brazilian population. Genet and Mol Biol 25: 357-360, 2002.