CARPs are E3 ligases that target apical caspases and p53

Cancer Biology and Therapy

Volumn 6, Issue 11, 2007, Pages 1676-1683

  Yang, Wensheng ^a   El Deiry, Wafik S ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Cancer; CARP1; CARP2; CARPs; Caspase; E3 ligase; hRFI; IAP; p53; Rififylin; Sakura

Indexed keywords

ANTINEOPLASTIC AGENT; CASPASE; CASPASE 8 10 ASSOCIATED RING PROTEIN 1; CASPASE 8 10 ASSOCIATED RING PROTEIN 2; INHIBITOR OF APOPTOSIS PROTEIN; PROTEIN P53; SERINE; UBIQUITIN PROTEIN LIGASE E3;

APOPTOSIS; CANCER CELL; CANCER CHEMOTHERAPY; CELL DEATH; CELL SURVIVAL; DNA DAMAGE; DRUG CYTOTOXICITY; ENDOSOME; ENZYME LOCALIZATION; ENZYME SPECIFICITY; ENZYME SUBSTRATE; GENE OVEREXPRESSION; GENE SILENCING; HUMAN; NONHUMAN; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN STRUCTURE; PROTEIN TARGETING; REGULATORY MECHANISM; REVIEW; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; UBIQUITINATION;

EID: 42549089229     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.6.11.4939     Document Type: Review

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