Transcriptional interruption of cAMP response element binding protein modulates superoxide dismutase and neuropeptide Y-mediated feeding behavior in freely moving rats

Journal of Neurochemistry

Volumn 105, Issue 4, 2008, Pages 1438-1449

  Hsieh, Yih Shou ^a   Yang, Shun Fa ^a   Chu, Shu Chen ^b   Ho, Ying Jui ^a   Kuo, Chih Sheng ^a   Kuo, Dong Yih ^a  

^a CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^b CENTRAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

Author keywords

Brain; Oxidative stress; Phenylpropanolamine; Signal transduction

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; NEUROPEPTIDE Y; PHENYLPROPANOLAMINE; SUPEROXIDE DISMUTASE;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANOREXIA; ARTICLE; BRAIN; CONTROLLED STUDY; DNA RESPONSIVE ELEMENT; DRUG EFFECT; DRUG INHIBITION; FEEDING BEHAVIOR; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN BINDING; RAT; SIGNAL TRANSDUCTION;

ANIMALS; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; FEEDING BEHAVIOR; MALE; NEUROPEPTIDE Y; PHENYLPROPANOLAMINE; RATS; RATS, WISTAR; SUPEROXIDE DISMUTASE; TRANSCRIPTION, GENETIC;

RATTUS;

EID: 42549086208     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2008.05246.x     Document Type: Article

References (56)

1. Akabayashi A., Zaia C. T., Gabriel S. M., Silva I., Cheung W. K. Leibowitz S. F. (1994) Intracerebroventricular injection of dibutyryl cyclic adenosine 3′,5′-monophosphate increases hypothalamic levels of neuropeptide Y. Brain Res. 660, 323 328.
2. Alexander M., Rothman R. B., Baumann M. H., Endres C. J., Brasic J. R. Wong D. F. (2005) Noradrenergic and dopaminergic effects of (+)-amphetamine-like stimulants in the baboon Papio anubis. Synapse 56, 94 99.
3. Andersson M., Konradi C. Cenci M. A. (2001) cAMP response element-binding protein is required for dopamine-dependent gene expression in the intact but not the dopamine-denervated striatum. J. Neurosci. 21, 9930 9943.
4. Borovicka M. C., Fuller M. A., Konicki P. E., White J. C., Steele V. M. Jaskiw G. E. (2002) Phenylpropanolamine appears not to promote weight loss in patients with schizophrenia who have gained weight during clozapine treatment. J. Clin. Psychiatry 63, 345 348.
5. Brenhouse H. C., Howe M. L. Stellar J. R. (2007) Differential activation of cAMP response element binding protein in discrete nucleus accumbens subregions during early and late cocaine sensitization. Behav. Neurosci. 121, 212 217.
6. Chance W. T., Sheriff S. Balasubramaniam A. (2000) Antagonism of NPY-induced feeding by pretreatment with cyclic AMP response element binding protein antisense oligonucleotide. Neuropeptides 34, 167 172.
7. Chen P. N., Chu S. C., Chiou H. L., Kuo W. H., Chiang C. L. Hsieh Y. S. (2006) Mulberry anthocyanins, cyanidin 3-rutinoside and cyaniding 3-glucoside, exhibited an inhibitory effect on the migration and invasion of a human lung cancer cell line. Cancer Lett. 235, 248 259.
8. Cheng J. T. Kuo D. Y. (2003) Both α1-adrenergic and D1-dopaminergic neurotransmissions are involved in phenylpropanolamine-mediated feeding suppression in mice. Neurosci. Lett. 347, 136 138.
9. Chiasson B. J., Hooper M. L., Murphy P. R. Robertson H. A. (1992) Antisense oligonucleotide eliminates in vivo expression of c-fos in mammalian brain. Eur. J. Pharmacol. 227, 451 453.
10. Choi K. H., Whisler K., Graham D. L. Self D. W. (2006) Antisense-induced reduction in nucleus accumbens cyclic AMP response element binding protein attenuates cocaine reinforcement. Neuroscience 137, 373 383.
11. Chomczynski P. Sacchi N. (1987) Single-step method of RNA isolation by acid quanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162, 156 159.
12. Colman E. (2005) Anorectics on trial: a half century of federal regulation of prescription appetite suppressants. Ann. Intern. Med. 143, 380 385.
13. Cooper T. V., Klesges R. C., Debon M. W., Zbikowski S. M., Johnson K. C. Clemens L. H. (2005) A placebo controlled randomized trial of the effects of phenylpropanolamine and nicotine gum on cessation rates and postcessation weight gain in women. Addict. Behav. 30, 61 75.
14. Das S., Grunert M., Williams L. Vincent S. R. (1997) NMDA and D1 receptors regulate the phosphorylation of CREB and the induction of c-fos in striatal neurons in primary culture. Synapse 25, 227 233.
15. Diepvens K., Westerterp K. R. Westerterp-Plantenga M. S. (2007) Obesity and thermogenesis related to the consumption of caffeine, ephedrine, capsaicin, and green tea. Am. J. Physiol. Regul. Integr. Comp. Physiol. 292, R77 R85.
16. Dominguez G. Kuhar M. J. (2004) Transcriptional regulation of the CART promoter in CATH.a cells. Brain Res. Mol. Brain Res. 126, 22 29.
17. Ghosh M. K. Cohen J. S. (1992) Oligodeoxynucleotides as antisense inhibitors of gene expression. Prog. Nucl. Acid Res. Mol. Biol. 42, 79 126.
18. Griffioen G. Thevelein J. M. (2002) Molecular mechanisms controlling the localization of protein kinase A. Curr. Genet. 41, 199 207.
19. Habener J. F., Miller C. P. Vallejo M. (1995) cAMP-dependent regulation of gene transcription by cAMP response element-binding protein and cAMP response element modulator. Vitam. Horm. 51, 1 57.
20. Hsieh Y. S., Hsu J. D., Yang S. F. Kuo D. Y. (2004) Immunohistochemical and genomic evidence for the involvement of hypothalamic neuropeptide Y in phenylpropranolamine-mediated appetite suppression. Peptides 25, 2155 2161.
21. Hsieh Y. S., Yang S. F., Chiou H. L. Kuo D. Y. (2005) Transcriptional involvement of protein kinase C-alpha isozyme in amphetamine-mediated appetite suppression. Eur. J. Neurosci. 22, 715 723.
22. Hsieh Y. S., Yang S. F., Chiou H. L. Kuo D. Y. (2006) Activations of c-fos/c-jun signaling are involved in the modulation of hypothalamic superoxide dismutase (SOD) and neuropeptide Y (NPY) gene expression in amphetamine-mediated appetite suppression. Toxicol. Appl. Pharm. 212, 99 109.
23. Hsieh Y. S., Yang S. F. Kuo D. Y. (2007) Intracerebral administration of protein kinase A or c-AMP response element binding protein antisense oligonucleotide can modulate amphetamine-mediated appetite suppression in free-moving rats. Am. J. Physiol. Endoc. Metab. 292, 123 131.
24. Hu D., Cao P., Thiels E., Chu C. T., Wu G. Y., Oury T. D. Klann E. (2007) Hippocampal long-term potentiation, memory, and longevity in mice that overexpress mitochondrial superoxide dismutase. Neurobiol. Learn. Mem. 87, 372 384.
25. Hull K. M., Sanderson W. D. Maher T. J. (1993) Effect of phenylpropanolamine and related compounds on beta-adrenoceptor-induced activation of adenylyl cyclase. Life Sci. 52, 1287 1294.
26. Hulsey M. G., Pless C. M., White B. D. Martin R. J. (1995) ICV administration of anti-NPY antisense oligonucleotide: effects on feeding behavior, body weight, peptide content and peptide release. Regul. Peptides 59, 207 214.
27. Jones D. C. Kuhar M. J. (2006) Cocaine-amphetamine-regulated transcript expression in the rat nucleus accumbens is regulated by adenylyl cyclase and the cyclic adenosine 5′-monophosphate/protein kinase a second messenger system. J. Pharmacol. Exp. Ther. 317, 454 461.
28. Kacew S., Narbaitz R. Stevenson A. J. (1977) The effects of chlorphentermine and phentermine on certain metabolic parameters associated with development of rat kidney and liver. Chem. Biol. Interact. 19, 61 76.
29. Konradi C., Cole R. L., Heckers S. Hyman S. E. (1994) Amphetamine regulates gene expression in rat striatum via transcription factor CREB. J. Neurosci. 14, 5623 5634.
30. Lambert P. D., Couceyro P. R., McGirr K. M., Dall Vechia S. E., Smith Y. Kuhar M. J. (1998) CART peptides in the central control of feeding and interactions with neuropeptide Y. Synapse 29, 293 298.
31. Larhammar D., Ericsson A. Persson H. (1987) Structure and expression of the rat neuropeptide Y gene. Proc. Natl Acad. Sci. USA 84, 2068 2072.
32. Levin O. S. (2005) 'Ephedron' encephalopathy. Zh. Nevrol. Psikhiatr. Im. S S Korsakova (Russ.) 105, 12 20.
33. Magni P. Barnea A. (1992) Forskolin and phorbol ester stimulation of neuropeptide Y (NPY) production and secretion by aggregating fetal brain cells in culture: evidence for regulation of NPY biosynthesis at transcriptional and posttranscriptional levels. Endocrinology 130, 976 984.
34. McDaid J., Graham M. P. Napier T. C. (2006) Methamphetamine-induced sensitization differentially alters pCREB and δFosB throughout the limbic circuit of the mammalian brain. Mol. Pharmacol. 70, 2064 2074.
35. Morris B. J. (1989) Neuronal localization of neuropeptide Y gene expression in rat brain. J. Comp. Neurol. 290, 358 368.
36. Nair A. Vaidya V. A. (2006) Cyclic AMP response element binding protein and brain-derived neurotrophic factor: molecules that modulate our mood? J. Biosci. 31, 423 434.
37. Nelson D. L. Gehlert D. R. (2006) Central nervous system biogenic amine targets for control of appetite and energy expenditure. Endocrine 29, 49 60.
38. Ogawa S. Pfaff D. W. (1998) Current status of antisense DNA methods in behavioral studies. Chem. Senses 23, 249 255.
39. Ogawa S., Brown H. E., Okano H. J. Pfaff D. W. (1995) Cellular uptake of intracerebrally administered oligodeoxynucleotides in mouse brain. Regul. Peptides 59, 143 149.
40. Pandey S. C. (2003) Anxiety and alcohol abuse disorders: a common role for CREB and its target, the neuropeptide Y gene. Trends Pharmacol. Sci. 24, 456 460.
41. Paxinos G. Watson C. (1986) The rat Brain in Stereotaxic Coordinates, 2nd Edn. Academic Press, Sydney, NSW.
42. Richard D. (1995) Exercise and the neurobiological control of food intake and energy expenditure. Int. J. Obes. 19, S73 S79.
43. Ritter R. C., Slusser P. G. Stone S. (1981) Glucoreceptors controlling feeding and blood glucose: location in the hindbrain. Science 213, 451 452.
44. Saito S. Y., Maruyama Y., Kamiyama S., Nakahata N. Ohizumi Y. (2004) Ephedrae herba in Mao-Bushi-Saishin-To inhibits IgE-mediated histamine release and increases cAMP content in RBL-2H3 cells. J. Pharmacol. Sci. 95, 41 46.
45. Schteingart D. E. (1992) Effectiveness of phenylpropanolamine in the management of moderate obesity. Int. J. Obes. 16, 487 493.
46. Scott L., Leddy M., Bernay F. Davot J. L. (2002) Evaluation of phenylpropanolamine in the treatment of urethral sphincter mechanism incompetence in the bitch. J. Small Anim. Pract. 43, 493 496.
47. Sheng P., Wang X. B., Ladenheim B., Epstein C. Cadet J. L. (1996) AP-1 DNA-binding activation by methamphetamine involves oxidative stress. Synapse 24, 213 217.
48. Sheriff S., Chance W. T., Fischer J. E. Balasubramaniam A. (1997) Neuropeptide Y treatment and food deprivation increase cyclic AMP response element-binding in rat hypothalamus. Mol. Pharmacol. 51, 597 604.
49. Sheriff S., Chance W. T., Iqbal S., Rizvi T. A., Xiao C., Kasckow J. W. Balasubramaniam A. (2003) Hypothalamic administration of cAMP agonist/PKA activator inhibits both schedule feeding and NPY-induced feeding in rats. Peptides 24, 245 254.
50. Shimizu-Albergine M., Ippolito D. L. Beavo J. A. (2001) Downregulation of fasting-induced cAMP response element-mediated gene induction by leptin in neuropeptide Y neurons of the arcuate nucleus. J. Neurosci. 21, 1238 1246.
51. Wellman P. J. Davies B. T. (1992) Reversal of cirazoline- and phenylpropanolamine-induced anorexia by the α1-adrenergic receptor antagonist prazosin. Pharmacol. Biochem. Behav. 42, 97 100.
52. Widnell K. L., Self D. W., Lane S. B., Russell D. S., Vaidya V., Miserendino M. J. D., Rubin C. S., Duman R. S. Nestler E. J. (1996) Regulation of CREB expression: in vivo evidence for a functional role in morphine action in the nucleus accumbens. J. Pharmacol. Exp. Ther. 276, 306 315.
53. Williams G., Bing C., Cai X. J., Harrold J. A., King P. J. Liu X. H. (2001) The hypothalamus and the control of energy homeostasis: different circuits, different purposes. Physiol. Behav. 74, 683 701.
54. Wynne K., Stanley S., McGowan B. Bloom S. (2005) Appetite control. J. Endocrinol. 184, 291 318.
55. Yee F., Ericson H., Reis D. J. Wahlestedt C. (1994) Cellular uptake of intracerebroventricularly administered biotin- or digoxigenin-labeled antisense oligodeoxynucleotides in the rat. Cell. Mol. Neurobiol. 14, 475 486.
56. Zhang M. Creese I. (1993) Antisense oligodeoxynucleotide reduces brain dopamine D2 receptors: behavioral correlates. Neurosci. Lett. 161, 223 226.