Divided doses for methadone maintenance

American Journal of Psychiatry

Volumn 165, Issue 3, 2008, Pages 303-305

  Adinoff, Bryon ^a,b,c  

^a VA NORTH TEXAS HEALTH CARE SYSTEM   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BUPRENORPHINE; METHADONE; OPIATE; NARCOTIC ANALGESIC AGENT;

AMYGDALOID NUCLEUS; DRUG DEPENDENCE; DRUG EFFECT; EDITORIAL; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HIPPOCAMPUS; INSULA; MAINTENANCE DRUG DOSE; NERVE POTENTIAL; PRIORITY JOURNAL; WITHDRAWAL SYNDROME; DOSE RESPONSE; DRUG ADMINISTRATION; HEROIN DEPENDENCE; HUMAN; METABOLISM; NOTE;

ANALGESICS, OPIOID; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; HEROIN DEPENDENCE; HUMANS; METHADONE;

EID: 42449154277     PISSN: 0002953X     EISSN: None     Source Type: Journal    
DOI: 10.1176/appi.ajp.2007.07121944     Document Type: Editorial

References (9)

1. Lowinson JH, Marion I, Joseph H, Langrod J, Salsitz EA, Payte JT, Dole VP: Methadone maintenance, in Substance Abuse: A Comprehensive Textbook. Edited by Lowinson JH, Ruiz P, Millman RB, Langrod JG. Philadelphia, Lippincott Williams and Wilkins, 2005, pp 616-633
2. Sinha R, Lacadie C, Skudlarski P, Fulbright RK, Rounsaville BJ, Kosten TR, Wexler BE: Neural activity associated with stress-induced cocaine craving: a functional magnetic resonance imaging study. Psychopharmacology (Berl) 2005; 183:171-180
3. Grusser SM, Wrase J, Klein S, Hermann D, Smolka MN, Ruf M, Weber-Fahr W, Flor H, Mann K, Braus DF, Heinz A: Cue-induced activation of the striatum and medial prefrontal cortex is associated with subsequent relapse in abstinent alcoholics. Psychopharmacology (Berl) 2004; 175:296-302
4. Dole VP, Nyswander ME, Kreek MJ: Narcotic blockade. Arch Intern Med 1966; 118:304-309
5. Dyer KR, White JM: Patterns of symptom complaints in methadone maintenance patients. Addiction 1997; 92:1445-1455
6. Kreek MJ: Medical safety and side effects of methadone in tolerant individuals. JAMA 1973; 223:665-668
7. Leavitt SB: Methadone dosing and safety in the treatment of opioid addiction (special report). Addiction Treatment Forum 2003; (Sept):1-8
8. Melichar JK, Hume SP, Williams TM, Daglish MR, Taylor LG, Ahmad R, Malizia AL, Brooks DJ, Myles JS, Lingford-Hughes A, Nutt DJ: Using [11C]diprenorphine to image opioid receptor occupancy by methadone in opioid addiction: clinical and preclinical studies. J Pharmacol Exp Ther 2005; 312:309-315
9. Rosado J, Walsh SL, Bigelow GE, Strain EC: Sublingual buprenorphine/naloxone precipitated withdrawal in subjects maintained on 100 mg of daily methadone. Drug Alcohol Depend 2007; 90:261-269