Multisystemic abscesses in African green monkeys (Chlorocebus aethiops) with invasive Klebsiella pneumoniae - Identification of the hypermucoviscosity phenotype

Veterinary Pathology

Volumn 45, Issue 2, 2008, Pages 226-231

  Twenhafel, N A ^a   Whitehouse, C A ^a   Stevens, E L ^a   Hottel, H E ^a   Foster, C D ^a   Gamble, S ^a   Abbott, S ^b   Janda, J M ^b   Kreiselmeier, N ^a   Steele, K E ^a  

^a UNITED STATES ARMY MEDICAL RESEARCH INSTITUTE OF INFECTIOUS DISEASES   (United States)

^b CALIFORNIA DEPARTMENT OF PUBLIC HEALTH   (United States)

Author keywords

Abscess; African green monkeys; Hypermucoviscosity; Invasive; Klebsiella pneumoniae

Indexed keywords

RNA 16S; VIRUS DNA;

ABSCESS; ANIMAL; ANIMAL DISEASE; ARTICLE; CERCOPITHECUS; CHEMISTRY; DNA SEQUENCE; ENTEROBACTER INFECTION; FEMALE; GENETICS; KLEBSIELLA PNEUMONIAE; MALE; MICROBIOLOGY; MONKEY DISEASE; PATHOGENICITY; PATHOLOGY; PHENOTYPE; VIRULENCE; VISCOSITY;

ABSCESS; ANIMALS; CERCOPITHECUS AETHIOPS; DNA, VIRAL; FEMALE; KLEBSIELLA INFECTIONS; KLEBSIELLA PNEUMONIAE; MALE; MONKEY DISEASES; PHENOTYPE; RNA, RIBOSOMAL, 16S; SEQUENCE ANALYSIS, DNA; VIRULENCE; VISCOSITY;

ANIMALIA; BACTERIA (MICROORGANISMS); CERCOPITHECIDAE; CERCOPITHECUS AETHIOPS; KLEBSIELLA PNEUMONIAE; THESPESIA GRANDIFLORA;

EID: 42449151669     PISSN: 03009858     EISSN: 15442217     Source Type: Journal    
DOI: 10.1354/vp.45-2-226     Document Type: Article

References (19)

1. Brisse S, Grimont F, Grimond P: The Genus Klebsiella. In: The Prokaryotes Proteobacteria: Gamma Subclass, ed. Dworkin M, 3rd ed., pp. 159-196. Springer, New York, NY, 2006
2. Chang SC, Fang CT, Hsueh PR, Chen YC, Luh KT: Klebsiella pneumoniae isolates causing liver abscess in Taiwan. Diagn Microbiol Infect Dis 37:279-284, 2000
3. Cheng DL, Liu YC, Yen MY, Liu CY, Wang RS: Septic metastatic lesions of pyogenic liver abscess. Their association with Klebsiella pneumoniae bacteremia in diabetic patients. Arch Intern Med 151:1557-1559, 1991
4. Chuang YP, Fang CT, Lai SY, Chang SC, Wang JT: Genetic determinants of capsular serotype K1 of Klebsiella pneumoniae causing primary pyogenic liver abscess. J Infect Dis 193:645-654, 2006
5. Fang CT, Chuang YP, Shun CT, Chang SC, Wang JT: A novel virulence gene in Klebsiella pneumoniae strains causing primary liver abscess and septic metastatic complications. J Exp Med 199:697-705, 2004
6. Fang FC, Sandler N, Libby SJ: Liver abscess caused by magA+ Klebsiella pneumoniae in North America. J Clin Microbiol 43:991-992, 2005
7. Gozalo A, Montoyo E: Klebsiella pneumoniae infection in a New World nonhuman primate center. Lab Primate Newsletter 30:13-20, 1991
8. Janda JM, Abbott SL: The Genera Klebsiella and Raoultella. In: The Enterobacteria, 3rd ed., pp. 115-135. ASM Press, Washington, DC, 2005
9. Kawai T: Hypermucoviscosity: an extremely sticky phenotype of Klebsiella pneumoniae associated with emerging destructive tissue abscess syndrome. Clin Infect Dis 42:1359-1361, 2006
10. Ko WC, Paterson DL, Sagnimeni AJ, Hansen DS, Von Gottberg A, Mohapatra S, Casellas JM, Goossens H, Mulazimoglu L, Trenholme G, Klugman KP, McCormack JG, Yu VL: Community-acquired Klebsiella pneumoniae bacteremia: global differences in clinical patterns. Emerg Infect Dis 8:160-166, 2002
11. Lederman ER, Crum NF: Pyogenic liver abscess with a focus on Klebsiella pneumoniae as a primary pathogen: an emerging disease with unique clinical characteristics. Am J Gastroenterol 100:322-331, 2005
12. Podschun R, Ullmann U: Klebsiella spp. as nosocomial pathogens: epidemiology, taxonomy, typing methods, and pathogenicity factors. Clin Microbiol Rev 11:589-603, 1998
13. Rahimian J, Wilson T, Oram V, Holzman RS: Pyogenic liver abscess: recent trends in etiology and mortality. Clin Infect Dis 39:1654-1659, 2004
14. Snyder SB, Lund JE, Bone J, Soave OA, Hirsch DC: A study of Klebsiella infections in owl monkeys (Aotus trivirgatus). J Am Vet Med Assoc 157:1935-1939, 1970
15. Struve C, Bojer M, Nielsen EM, Hansen DS, Krogfelt KA: Investigation of the putative virulence gene magA in a worldwide collection of 495 Klebsiella isolates: magA is restricted to the gene cluster of Klebsiella pneumoniae capsule serotype K1. J Med Microbiol 54:1111-1113, 2005
16. Vasselon T, Sansonetti PJ, Nassif X: Nucleotide sequence of rmpB, a Klebsiella pneumoniae gene that positively controls, colanic biosynthesis in Escherichia coli. Res Microbiol 142:47-54, 1991
17. Wang JH, Liu YC, Lee SS, Yen MY, Chen YS, Wang JH, Wann SR, Lin HH: Primary liver abscess due to Klebsiella pneumoniae in Taiwan. Clin Infect Dis 26:1434-1438, 1998
18. Yeh KM, Kurup A, Siu LK, Koh YL, Fung CP, Lin JC, Chen TL, Chang FY, Koh TH: Capsular serotype K1 or K2, rather than magA and rmpA, is a major virulence determinant for Klebsiella pneumoniae liver abscess in Singapore and Taiwan. J Clin Microbiol 45:466-471, 2007
19. Yu WL, Ko WC, Cheng KC, Lee HC, Ke DS, Lee CC, Fung CP, Chuang YC: Association between rmpA and magA genes and clinical syndromes caused by Klebsiella pneumoniae in Taiwan. Clin Infect Dis 42:1351-1358, 2006