메뉴 건너뛰기




Volumn 3, Issue 2, 2008, Pages 119-125

Targeted therapies and surgical issues in gastrointestinal cancers

Author keywords

Angiogenesis; Bevacizumab; Cetuximab; Complications; Epidermal growth factor; Panitumumab; Targeted therapy; Vascular endothelial growth factor

Indexed keywords


EID: 42449148230     PISSN: 17762596     EISSN: 1776260X     Source Type: Journal    
DOI: 10.1007/s11523-008-0075-8     Document Type: Article
Times cited : (10)

References (46)
  • 1
    • 0035253739 scopus 로고    scopus 로고
    • Phase i safety and pharmacokinetic study of recombinant human anti-vascular endothelial growth factor in patients with advanced cancer
    • 3
    • Gordon MS et al (2001) Phase I safety and pharmacokinetic study of recombinant human anti-vascular endothelial growth factor in patients with advanced cancer. J Clin Oncol 19(3):843-850
    • (2001) J Clin Oncol , vol.19 , pp. 843-850
    • Gordon, M.S.1
  • 2
    • 34447108810 scopus 로고    scopus 로고
    • Vascular endothelial growth factor: Biology and therapeutic applications
    • 7-8
    • Ho QT, Kuo CJ (2007) Vascular endothelial growth factor: biology and therapeutic applications. Int J Biochem Cell Biol 39(7-8):1349-1357
    • (2007) Int J Biochem Cell Biol , vol.39 , pp. 1349-1357
    • Ho, Q.T.1    Kuo, C.J.2
  • 4
    • 24344442899 scopus 로고    scopus 로고
    • Surgical wound healing complications in metastatic colorectal cancer patients treated with bevacizumab
    • 3
    • Scappaticci FA et al (2005) Surgical wound healing complications in metastatic colorectal cancer patients treated with bevacizumab. J Surg Oncol 91(3):173-180
    • (2005) J Surg Oncol , vol.91 , pp. 173-180
    • Scappaticci, F.A.1
  • 5
    • 24644454338 scopus 로고    scopus 로고
    • Surgical resection after downsizing of colorectal liver metastasis in the era of bevacizumab
    • 22
    • Ellis LM, Curley SA, Grothey A (2005) Surgical resection after downsizing of colorectal liver metastasis in the era of bevacizumab. J Clin Oncol 23(22):4853-4855
    • (2005) J Clin Oncol , vol.23 , pp. 4853-4855
    • Ellis, L.M.1    Curley, S.A.2    Grothey, A.3
  • 6
    • 33846603686 scopus 로고    scopus 로고
    • Lack of evidence for increased operative morbidity after hepatectomy with perioperative use of bevacizumab: A matched case-control study
    • 2
    • D'Angelica M et al (2007) Lack of evidence for increased operative morbidity after hepatectomy with perioperative use of bevacizumab: a matched case-control study. Ann Surg Oncol 14(2):759-765
    • (2007) Ann Surg Oncol , vol.14 , pp. 759-765
    • D'Angelica, M.1
  • 8
    • 37249002806 scopus 로고    scopus 로고
    • Addition of bevacizumab to irinotecan- and oxaliplatin-based preoperative chemotherapy regimens does not increase morbidity after resection of colorectal liver metastases
    • 1
    • Reddy SK et al (2008) Addition of bevacizumab to irinotecan- and oxaliplatin-based preoperative chemotherapy regimens does not increase morbidity after resection of colorectal liver metastases. J Am Coll Surg 206(1):96-106
    • (2008) J Am Coll Surg , vol.206 , pp. 96-106
    • Reddy, S.K.1
  • 9
    • 2542561964 scopus 로고    scopus 로고
    • Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
    • 23
    • Hurwitz H et al (2004) Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med 350(23):2335-2342
    • (2004) N Engl J Med , vol.350 , pp. 2335-2342
    • Hurwitz, H.1
  • 10
    • 34248173883 scopus 로고    scopus 로고
    • Bevacizumab in combination with oxaliplatin, fluorouracil, and leucovorin (FOLFOX4) for previously treated metastatic colorectal cancer: Results from the Eastern Cooperative Oncology Group Study E3200
    • 12
    • Giantonio BJ et al (2007) Bevacizumab in combination with oxaliplatin, fluorouracil, and leucovorin (FOLFOX4) for previously treated metastatic colorectal cancer: results from the Eastern Cooperative Oncology Group Study E3200. J Clin Oncol 25(12):1539-1544
    • (2007) J Clin Oncol , vol.25 , pp. 1539-1544
    • Giantonio, B.J.1
  • 11
    • 34249894171 scopus 로고    scopus 로고
    • Gastrointestinal perforation due to bevacizumab in colorectal cancer
    • 6
    • Saif MW, Elfiky A, Salem RR (2007) Gastrointestinal perforation due to bevacizumab in colorectal cancer. Ann Surg Oncol 14(6):1860-1869
    • (2007) Ann Surg Oncol , vol.14 , pp. 1860-1869
    • Saif, M.W.1    Elfiky, A.2    Salem, R.R.3
  • 12
    • 40149096054 scopus 로고    scopus 로고
    • Management of bevacizumab-associated bowel perforation: A case series and review of the literature
    • DOI 10.1093/annonc/mdm508
    • Badgwell BD et al (2007) Management of bevacizumab-associated bowel perforation: a case series and review of the literature. Ann Oncol. DOI 10.1093/annonc/mdm508
    • (2007) Ann Oncol
    • Badgwell, B.D.1    Al, E.2
  • 13
    • 34249902080 scopus 로고    scopus 로고
    • Incidence of gastrointestinal perforations and bleeding in patients starting bevacizumab treatment in first-line mCRC without primary tumor resection: Preliminary results from the First BEATrial
    • Abstract 248
    • Kretzschmar A, Cunningham D, Berry S (2006) Incidence of gastrointestinal perforations and bleeding in patients starting bevacizumab treatment in first-line mCRC without primary tumor resection: preliminary results from the First BEATrial. 2006 American Society of Clinical Oncology Gastrointestinal Cancer Symposium, Abstract 248
    • (2006) 2006 American Society of Clinical Oncology Gastrointestinal Cancer Symposium
    • Kretzschmar, A.1    Cunningham, D.2    Berry, S.3
  • 14
    • 42449126355 scopus 로고    scopus 로고
    • Risk factors for gastrointestinal perforations in patients with metastatic colorectal cancer receiving bevacizumab plus chemotherapy
    • Abstract 3535
    • Sugrue M, Kozloff M, Hainsworth J (2006) Risk factors for gastrointestinal perforations in patients with metastatic colorectal cancer receiving bevacizumab plus chemotherapy. 2006 American Society of Clinical Oncology Annual Meeting, Abstract 3535
    • (2006) 2006 American Society of Clinical Oncology Annual Meeting
    • Sugrue, M.1    Kozloff, M.2    Hainsworth, J.3
  • 15
    • 34447502449 scopus 로고    scopus 로고
    • Experience with bevacizumab in the management of epithelial ovarian cancer
    • 20
    • Burger RA (2007) Experience with bevacizumab in the management of epithelial ovarian cancer. J Clin Oncol 25(20):2902-2908
    • (2007) J Clin Oncol , vol.25 , pp. 2902-2908
    • Burger, R.A.1
  • 16
    • 38649143684 scopus 로고    scopus 로고
    • Incidence, consequences, and risk factors for anastomotic dehiscence after colorectal surgery: A prospective monocentric study
    • 3
    • Buchs NC et al (2008) Incidence, consequences, and risk factors for anastomotic dehiscence after colorectal surgery: a prospective monocentric study. Int J Colorectal Dis 23(3):265-270
    • (2008) Int J Colorectal Dis , vol.23 , pp. 265-270
    • Buchs, N.C.1
  • 17
    • 20544478429 scopus 로고    scopus 로고
    • Addition of bevacizumab to bolus fluorouracil and leucovorin in first-line metastatic colorectal cancer: Results of a randomized phase II trial
    • 16
    • Kabbinavar FF et al (2005) Addition of bevacizumab to bolus fluorouracil and leucovorin in first-line metastatic colorectal cancer: results of a randomized phase II trial. J Clin Oncol 23(16):3697-3705
    • (2005) J Clin Oncol , vol.23 , pp. 3697-3705
    • Kabbinavar, F.F.1
  • 18
    • 24644450665 scopus 로고    scopus 로고
    • Treatment strategy for patients with colorectal cancer and synchronous irresectable liver metastases
    • 9
    • Benoist S et al (2005) Treatment strategy for patients with colorectal cancer and synchronous irresectable liver metastases. Br J Surg 92(9):1155-1160
    • (2005) Br J Surg , vol.92 , pp. 1155-1160
    • Benoist, S.1
  • 19
    • 33846592819 scopus 로고    scopus 로고
    • Asymptomatic colorectal cancer with un-resectable liver metastases: Immediate colorectal resection or up-front systemic chemotherapy?
    • 2
    • Muratore A et al (2007) Asymptomatic colorectal cancer with un-resectable liver metastases: immediate colorectal resection or up-front systemic chemotherapy? Ann Surg Oncol 14(2):766-770
    • (2007) Ann Surg Oncol , vol.14 , pp. 766-770
    • Muratore, A.1
  • 20
    • 0032699922 scopus 로고    scopus 로고
    • Nonoperative management of primary colorectal cancer in patients with stage IV disease
    • 7
    • Scoggins CR et al (1999) Nonoperative management of primary colorectal cancer in patients with stage IV disease. Ann Surg Oncol 6(7):651-657
    • (1999) Ann Surg Oncol , vol.6 , pp. 651-657
    • Scoggins, C.R.1
  • 21
    • 0033038014 scopus 로고    scopus 로고
    • Effect of vascular endothelial growth factor on hepatic regenerative activity following partial hepatectomy in rats
    • 5
    • Assy N et al (1999) Effect of vascular endothelial growth factor on hepatic regenerative activity following partial hepatectomy in rats. J Hepatol 30(5):911-915
    • (1999) J Hepatol , vol.30 , pp. 911-915
    • Assy, N.1
  • 22
    • 0038778618 scopus 로고    scopus 로고
    • Chronobiology of the proliferative events related to angiogenesis in mice liver regeneration after partial hepatectomy
    • 4
    • Furnus CC et al (2003) Chronobiology of the proliferative events related to angiogenesis in mice liver regeneration after partial hepatectomy. Cell Biol Int 27(4):383-386
    • (2003) Cell Biol Int , vol.27 , pp. 383-386
    • Furnus, C.C.1
  • 23
    • 0035860182 scopus 로고    scopus 로고
    • Vascular endothelial growth factor and angiopoietin in liver regeneration
    • 1
    • Kraizer Y et al (2001) Vascular endothelial growth factor and angiopoietin in liver regeneration. Biochem Biophys Res Commun 287(1):209-215
    • (2001) Biochem Biophys Res Commun , vol.287 , pp. 209-215
    • Kraizer, Y.1
  • 24
    • 33750957147 scopus 로고    scopus 로고
    • Liver histology and surgical outcomes after preoperative chemotherapy with fluorouracil plus oxaliplatin in colorectal cancer liver metastases
    • 31
    • Aloia T et al (2006) Liver histology and surgical outcomes after preoperative chemotherapy with fluorouracil plus oxaliplatin in colorectal cancer liver metastases. J Clin Oncol 24(31):4983-4990
    • (2006) J Clin Oncol , vol.24 , pp. 4983-4990
    • Aloia, T.1
  • 25
    • 0347481231 scopus 로고    scopus 로고
    • Perioperative complications in patients undergoing major liver resection with or without neoadjuvant chemotherapy
    • 8
    • Parikh AA et al (2003) Perioperative complications in patients undergoing major liver resection with or without neoadjuvant chemotherapy. J Gastrointest Surg 7(8):1082-1088
    • (2003) J Gastrointest Surg , vol.7 , pp. 1082-1088
    • Parikh, A.A.1
  • 26
    • 33646457231 scopus 로고    scopus 로고
    • Chemotherapy regimen predicts steatohepatitis and an increase in 90-day mortality after surgery for hepatic colorectal metastases
    • 13
    • Vauthey JN et al (2006) Chemotherapy regimen predicts steatohepatitis and an increase in 90-day mortality after surgery for hepatic colorectal metastases. J Clin Oncol 24(13):2065-2072
    • (2006) J Clin Oncol , vol.24 , pp. 2065-2072
    • Vauthey, J.N.1
  • 27
    • 39149139499 scopus 로고    scopus 로고
    • Bevacizumab plus XELOX as neoadjuvant therapy for patients with potentially curable metastatic colorectal cancer
    • 2007 ASCO Annual Meeting Proceedings Part I
    • Gruenberger T, Tamandi D, Puhalla H, Scheithauer W, Zielinski C, Gruenberger B (2007) Bevacizumab plus XELOX as neoadjuvant therapy for patients with potentially curable metastatic colorectal cancer. J Clin Oncol 25(18S) (2007 ASCO Annual Meeting Proceedings Part I):4064
    • (2007) J Clin Oncol , vol.25 , Issue.18 , pp. 4064
    • Gruenberger, T.1    Tamandi, D.2    Puhalla, H.3    Scheithauer, W.4    Zielinski, C.5    Gruenberger, B.6
  • 28
    • 37048998995 scopus 로고    scopus 로고
    • Bevacizumab improves pathologic response and protects against hepatic injury in patients treated with oxaliplatin-based chemotherapy for colorectal liver metastases
    • 12
    • Ribero D et al (2007) Bevacizumab improves pathologic response and protects against hepatic injury in patients treated with oxaliplatin-based chemotherapy for colorectal liver metastases. Cancer 110(12):2761-2767
    • (2007) Cancer , vol.110 , pp. 2761-2767
    • Ribero, D.1
  • 29
    • 23044510046 scopus 로고    scopus 로고
    • Safety and pharmacokinetics of the dual action Raf kinase and vascular endothelial growth factor receptor inhibitor, BAY 43-9006, in patients with advanced, refractory solid tumors
    • 15
    • Clark JW et al (2005) Safety and pharmacokinetics of the dual action Raf kinase and vascular endothelial growth factor receptor inhibitor, BAY 43-9006, in patients with advanced, refractory solid tumors. Clin Cancer Res 11(15):5472-5480
    • (2005) Clin Cancer Res , vol.11 , pp. 5472-5480
    • Clark, J.W.1
  • 30
    • 27144527372 scopus 로고    scopus 로고
    • Phase i study to determine the safety and pharmacokinetics of the novel Raf kinase and VEGFR inhibitor BAY 43-9006, administered for 28 days on/7 days off in patients with advanced, refractory solid tumors
    • 10
    • Moore M et al (2005) Phase I study to determine the safety and pharmacokinetics of the novel Raf kinase and VEGFR inhibitor BAY 43-9006, administered for 28 days on/7 days off in patients with advanced, refractory solid tumors. Ann Oncol 16(10):1688-1694
    • (2005) Ann Oncol , vol.16 , pp. 1688-1694
    • Moore, M.1
  • 31
    • 33749017926 scopus 로고    scopus 로고
    • Phase II study of sorafenib in patients with advanced hepatocellular carcinoma
    • 26
    • Abou-Alfa GK et al (2006) Phase II study of sorafenib in patients with advanced hepatocellular carcinoma. J Clin Oncol 24(26):4293-4300
    • (2006) J Clin Oncol , vol.24 , pp. 4293-4300
    • Abou-Alfa, G.K.1
  • 32
    • 58149496852 scopus 로고    scopus 로고
    • Sorafenib and surgical complications: A case report of adverse reaction to sorafenib during treatment for renal cell carcinoma
    • DOI 10.1016/j.ejso.2007.09.009
    • Eng FC et al (2007) Sorafenib and surgical complications: a case report of adverse reaction to sorafenib during treatment for renal cell carcinoma. Eur J Surg Oncol DOI 10.1016/j.ejso.2007.09.009
    • (2007) Eur J Surg Oncol
    • Eng, F.C.1    Al, E.2
  • 34
    • 32044464123 scopus 로고    scopus 로고
    • Epidermal growth factor receptor (EGFR) signaling in cancer
    • 1
    • Normanno N et al (2006) Epidermal growth factor receptor (EGFR) signaling in cancer. Gene 366(1):2-16
    • (2006) Gene , vol.366 , pp. 2-16
    • Normanno, N.1
  • 35
    • 33746485766 scopus 로고    scopus 로고
    • Epidermal growth factor receptor targeting in cancer
    • 4
    • Mendelsohn J, Baselga J (2006) Epidermal growth factor receptor targeting in cancer. Semin Oncol 33(4):369-385
    • (2006) Semin Oncol , vol.33 , pp. 369-385
    • Mendelsohn, J.1    Baselga, J.2
  • 36
    • 42449113089 scopus 로고    scopus 로고
    • ImClone Systems Inc./Bristol-Myers Squibb Co.
    • Erbitux (Cetuximab) Package Insert; ImClone Systems Inc./Bristol-Myers Squibb Co.
    • Erbitux (Cetuximab) Package Insert
  • 37
    • 3242720345 scopus 로고    scopus 로고
    • Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer
    • 4
    • Cunningham D et al (2004) Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer. N Engl J Med 351(4):337-345
    • (2004) N Engl J Med , vol.351 , pp. 337-345
    • Cunningham, D.1
  • 38
    • 34447264101 scopus 로고    scopus 로고
    • Randomized phase III study of irinotecan and 5-FU/FA with or without cetuximab in the first-line treatment of patients with metastatic colorectal cancer (mCRC): The CRYSTAL trial
    • 2007 ASCO Annual Meeting Proceedings Part I
    • Van Cutsem E, Nowacki M, Lang I, Cascinu S, Shchepotin I, Maurel J, Rougier P, Cunningham D, Nippgen J, Köhne C (2007) Randomized phase III study of irinotecan and 5-FU/FA with or without cetuximab in the first-line treatment of patients with metastatic colorectal cancer (mCRC): The CRYSTAL trial. J Clin Oncol 25(18S) (2007 ASCO Annual Meeting Proceedings Part I):4000
    • (2007) J Clin Oncol , vol.25 , Issue.18 , pp. 4000
    • Van Cutsem, E.1    Nowacki, M.2    Lang, I.3    Cascinu, S.4    Shchepotin, I.5    Maurel, J.6    Rougier, P.7    Cunningham, D.8    Nippgen, J.9    Köhne, C.10
  • 39
    • 33750905700 scopus 로고    scopus 로고
    • Phase III study of irinotecan/5FU/LV (FOLFIRI) or oxaliplatin/5FU/LV (FOLFOX) ± cetuximab for patients (pts) with untreated metastatic adenocarcinoma of the colon or rectum (MCRC): CALGB 80203 preliminary results
    • 2006 ASCO Annual Meeting Proceedings Part I
    • Venook A et al (2006) Phase III study of irinotecan/5FU/LV (FOLFIRI) or oxaliplatin/5FU/LV (FOLFOX) ± cetuximab for patients (pts) with untreated metastatic adenocarcinoma of the colon or rectum (MCRC): CALGB 80203 preliminary results. J Clin Oncol 24(18S) (2006 ASCO Annual Meeting Proceedings Part I):3509
    • (2006) J Clin Oncol , vol.24 , Issue.18 , pp. 3509
    • Venook, A.1    Al, E.2
  • 40
    • 0030774045 scopus 로고    scopus 로고
    • Induction of apoptosis and cell cycle arrest by CP-358,774, an inhibitor of epidermal growth factor receptor tyrosine kinase
    • 21
    • Moyer JD et al (1997) Induction of apoptosis and cell cycle arrest by CP-358,774, an inhibitor of epidermal growth factor receptor tyrosine kinase. Cancer Res 57(21):4838-4848
    • (1997) Cancer Res , vol.57 , pp. 4838-4848
    • Moyer, J.D.1
  • 41
    • 42449143142 scopus 로고    scopus 로고
    • Genentech Biooncology Inc.
    • Tarceva Package Insert; Genentech Biooncology Inc.
    • Tarceva Package Insert
  • 44
    • 34548782293 scopus 로고    scopus 로고
    • Gastrointestinal stromal tumours: Clinical overview, surgery and recent advances in imatinib mesylate therapy
    • 8
    • Samelis GF, Ekmektzoglou KA, Zografos GC (2007) Gastrointestinal stromal tumours: clinical overview, surgery and recent advances in imatinib mesylate therapy. Eur J Surg Oncol 33(8):942-950
    • (2007) Eur J Surg Oncol , vol.33 , pp. 942-950
    • Samelis, G.F.1    Ekmektzoglou, K.A.2    Zografos, G.C.3
  • 45
    • 33845633389 scopus 로고    scopus 로고
    • Surgical resection of gastrointestinal stromal tumors after treatment with imatinib
    • 1
    • Andtbacka RH et al (2007) Surgical resection of gastrointestinal stromal tumors after treatment with imatinib. Ann Surg Oncol 14(1):14-24
    • (2007) Ann Surg Oncol , vol.14 , pp. 14-24
    • Andtbacka, R.H.1
  • 46
    • 34250632828 scopus 로고    scopus 로고
    • Surgical interventions for focal progression of advanced gastrointestinal stromal tumors during imatinib therapy
    • 3
    • Hasegawa J et al (2007) Surgical interventions for focal progression of advanced gastrointestinal stromal tumors during imatinib therapy. Int J Clin Oncol 12(3):212-217
    • (2007) Int J Clin Oncol , vol.12 , pp. 212-217
    • Hasegawa, J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.