Impact of blood sampling on the circulating matrix metalloproteinases 1, 2, 3, 7, 8, and 9

Clinical Chemistry

Volumn 54, Issue 4, 2008, Pages 772-774

  Jung, Klaus ^a   Klotzek, Silke ^a   Stephan, Carsten ^a   Mannello, Ferdinando ^b   Lein, Michael ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b UNIVERSITY OF URBINO   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CITRATE DISODIUM; COLLAGENASE 3; GELATINASE A; GELATINASE B; HEPARIN; INTERSTITIAL COLLAGENASE; MACROPHAGE ELASTASE; MATRILYSIN; MATRIX METALLOPROTEINASE; NEUTROPHIL COLLAGENASE; STROMELYSIN; TISSUE INHIBITOR OF METALLOPROTEINASE 1;

ADULT; BLOOD CLOTTING; BLOOD SAMPLING; CIRCULATION; CONTROLLED STUDY; DIAGNOSTIC PROCEDURE; FEMALE; HUMAN; HUMAN EXPERIMENT; LETTER; LEUKOCYTE; MALE; MONITORING; NON INVASIVE PROCEDURE; NORMAL HUMAN; THROMBOCYTE; VEIN PUNCTURE; BLOOD;

ADULT; BLOOD SPECIMEN COLLECTION; FEMALE; HUMANS; MALE; MATRIX METALLOPROTEINASE 1; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 3; MATRIX METALLOPROTEINASE 7; MATRIX METALLOPROTEINASE 8; MATRIX METALLOPROTEINASE 9; MATRIX METALLOPROTEINASES;

EID: 42449136580     PISSN: 00099147     EISSN: None     Source Type: Journal    
DOI: 10.1373/clinchem.2007.099937     Document Type: Letter

References (5)

1. Zucker S, Doshi K, Cao J. Measurement of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMP) in blood and urine: potential clinical applications. Adv Clin Chem 2004;38:37-85.
2. Jung K, Meisser A, Bischof P. Blood sampling as critical preanalytical determinant to use circulating MMP and TIMP as surrogate markers for pathological processes. Int J Cancer 2005;116:1000-1.
3. Mannello F, Tonti GA, Tanus-Santos JE, Gerlach RF. Silicate increases the release of MMP-9 forms in peripheral blood: why gelatin zymography differs significantly in citrate plasma and serum obtained with or without clot activators. Clin Chem 2007;53:1981-2.
4. Mannello F, Tonti GA. Gelatinase concentrations and zymographic profiles in human breast cancer: matrix metalloproteinases circulating in plasma are better markers for the subclassification and early prediction of cancer: the coagulation/fibrinolysis pathways alter the release, activation and recovery of different gelatinases in serum. Int J Cancer 2007;121:216-8.
5. Makowski GS, Ramsby ML. Use of citrate to minimize neutrophil matrix metalloproteinase-9 in human plasma. Anal Biochem 2003;322:283-6.