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Volumn 105, Issue 12, 2008, Pages 4757-4762

ATP-dependent activation of p21WAF1/CIP1-associated Cdk2 by Cdc6

Author keywords

Cy motif; DNA damage; Intra S checkpoint; MMS; Walker B domain

Indexed keywords

ADENOSINE TRIPHOSPHATE; CELL CYCLE PROTEIN 6; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE INHIBITOR 1; ADENOSINE TRIPHOSPHATASE; CDC6 PROTEIN, RAT; CELL CYCLE PROTEIN; CYCLIN DEPENDENT KINASE INHIBITOR 1A; CYCLIN DEPENDENT KINASE INHIBITOR 1B; CYCLINE; MESYLIC ACID METHYL ESTER; NONHISTONE PROTEIN; UNCLASSIFIED DRUG;

EID: 42449133406     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0706392105     Document Type: Article
Times cited : (18)

References (34)
  • 1
    • 0033756308 scopus 로고    scopus 로고
    • Chromatin association of human origin recognition complex, cdc6, and minichromosome maintenance proteins during the cell cycle: Assembly of prereplication complexes in late mitosis
    • Mendez J, Stillman B (2000) Chromatin association of human origin recognition complex, cdc6, and minichromosome maintenance proteins during the cell cycle: Assembly of prereplication complexes in late mitosis. Mol Cell Biol 20:8602-8612.
    • (2000) Mol Cell Biol , vol.20 , pp. 8602-8612
    • Mendez, J.1    Stillman, B.2
  • 2
    • 0037022387 scopus 로고    scopus 로고
    • Analysis of Cdc6 function in the assembly of mammalian prereplication complexes
    • Cook JG, et al. (2002) Analysis of Cdc6 function in the assembly of mammalian prereplication complexes. Proc Natl Acad Sci USA 99:1347-1352.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 1347-1352
    • Cook, J.G.1
  • 3
    • 0035997368 scopus 로고    scopus 로고
    • DNA replication in eukaryotic cells
    • Bell SP, Dutta A (2002) DNA replication in eukaryotic cells. Annu Rev Biochem 71:333-374.
    • (2002) Annu Rev Biochem , vol.71 , pp. 333-374
    • Bell, S.P.1    Dutta, A.2
  • 4
    • 0033790340 scopus 로고    scopus 로고
    • Regulation of chromosome replication
    • Kelly TJ, Brown GW (2000) Regulation of chromosome replication. Annu Rev Biochem 69:829-880.
    • (2000) Annu Rev Biochem , vol.69 , pp. 829-880
    • Kelly, T.J.1    Brown, G.W.2
  • 5
    • 0035012849 scopus 로고    scopus 로고
    • Initiating DNA synthesis: From recruiting to activating the MCM complex
    • Lei M, Tye BK (2001) Initiating DNA synthesis: From recruiting to activating the MCM complex. J Cell Sci 114:1447-1454.
    • (2001) J Cell Sci , vol.114 , pp. 1447-1454
    • Lei, M.1    Tye, B.K.2
  • 6
    • 0032807099 scopus 로고    scopus 로고
    • The Cdc6 nucleotide-binding site regulates its activity in DNA replication in human cells
    • Herbig U, Marlar CA, Fanning E (1999) The Cdc6 nucleotide-binding site regulates its activity in DNA replication in human cells. Mol Cell Biol 10:2631-2645.
    • (1999) Mol Cell Biol , vol.10 , pp. 2631-2645
    • Herbig, U.1    Marlar, C.A.2    Fanning, E.3
  • 7
    • 0034063607 scopus 로고    scopus 로고
    • ATPase switches controlling DNA replication initiation
    • Lee DG, Bell SP (2000) ATPase switches controlling DNA replication initiation. Curr Opin Cell Biol 12:280-285.
    • (2000) Curr Opin Cell Biol , vol.12 , pp. 280-285
    • Lee, D.G.1    Bell, S.P.2
  • 8
    • 0033556238 scopus 로고    scopus 로고
    • Phosphorylation of mammalian CDC6 by cyclin A/CDK2 regulates its subcellular localization
    • Petersen BO, Lukas J, Sørensen CS, Bartek J, Helin K (1999) Phosphorylation of mammalian CDC6 by cyclin A/CDK2 regulates its subcellular localization. EMBO J 18:396-401.
    • (1999) EMBO J , vol.18 , pp. 396-401
    • Petersen, B.O.1    Lukas, J.2    Sørensen, C.S.3    Bartek, J.4    Helin, K.5
  • 9
    • 0034641724 scopus 로고    scopus 로고
    • Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro
    • Matsuoka S, et al. (2000) Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro. Proc Natl Acad Sci USA 97:10389-10394.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 10389-10394
    • Matsuoka, S.1
  • 10
    • 3943107573 scopus 로고    scopus 로고
    • Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints
    • Sancar A, Lindsey-Boltz LA, Unsal-Kacmaz K, Linn S (2004) Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints. Annu Rev Biochem 73:39-85.
    • (2004) Annu Rev Biochem , vol.73 , pp. 39-85
    • Sancar, A.1    Lindsey-Boltz, L.A.2    Unsal-Kacmaz, K.3    Linn, S.4
  • 12
    • 17044413219 scopus 로고    scopus 로고
    • The S phase checkpoint: When the crowd meets at the fork
    • Gottifredi V, Prives C (2005) The S phase checkpoint: When the crowd meets at the fork. Semin Cell Dev Biol 16:355-368.
    • (2005) Semin Cell Dev Biol , vol.16 , pp. 355-368
    • Gottifredi, V.1    Prives, C.2
  • 13
    • 85047680162 scopus 로고    scopus 로고
    • p53 accumulates but is functionally impaired when DNA synthesis is blocked
    • Gottifredi V, Shieh S, Taya Y, Prives C (2001) p53 accumulates but is functionally impaired when DNA synthesis is blocked. Proc Natl Acad Sci USA 98:1036-1041.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 1036-1041
    • Gottifredi, V.1    Shieh, S.2    Taya, Y.3    Prives, C.4
  • 14
    • 33846908937 scopus 로고    scopus 로고
    • p53-dependent p21 mRNA elongation is impaired when DNA replication is stalled
    • Mattia M, Gottifredi V, McKinney K, Prives C (2007) p53-dependent p21 mRNA elongation is impaired when DNA replication is stalled. Mol Cell Biol 27:1309-1320.
    • (2007) Mol Cell Biol , vol.27 , pp. 1309-1320
    • Mattia, M.1    Gottifredi, V.2    McKinney, K.3    Prives, C.4
  • 15
    • 44449084595 scopus 로고    scopus 로고
    • Chemical DNA damage activates p21(WAF1/CIP1)-dependent intra-S checkpoint
    • Kan Q, Jinno S, Yamamoto H, Okayama H (2007) Chemical DNA damage activates p21(WAF1/CIP1)-dependent intra-S checkpoint. FEBS Lett 581:5879-5884.
    • (2007) FEBS Lett , vol.581 , pp. 5879-5884
    • Kan, Q.1    Jinno, S.2    Yamamoto, H.3    Okayama, H.4
  • 17
    • 0037034864 scopus 로고    scopus 로고
    • Cdc6 requires anchorage for its expression
    • Jinno S, Yageta M, Nagata A, Okayama H (2002) Cdc6 requires anchorage for its expression. Oncogene 21:1777-1784.
    • (2002) Oncogene , vol.21 , pp. 1777-1784
    • Jinno, S.1    Yageta, M.2    Nagata, A.3    Okayama, H.4
  • 18
    • 0031921561 scopus 로고    scopus 로고
    • Human CDC6/Cdc18 associates with Orc1 and cyclin-cdk and is selectively eliminated from the nucleus at the onset of S phase
    • Saha P, et al. (1998) Human CDC6/Cdc18 associates with Orc1 and cyclin-cdk and is selectively eliminated from the nucleus at the onset of S phase. Mol Cell Biol 18:2758-2767.
    • (1998) Mol Cell Biol , vol.18 , pp. 2758-2767
    • Saha, P.1
  • 20
    • 33746860263 scopus 로고    scopus 로고
    • Structural basis for ATP-dependent DnaA assembly and replication-origin remodeling
    • Erzberger JP, Mott ML, Berger JM (2006) Structural basis for ATP-dependent DnaA assembly and replication-origin remodeling. Nat Struct Mol Biol 13:676-683.
    • (2006) Nat Struct Mol Biol , vol.13 , pp. 676-683
    • Erzberger, J.P.1    Mott, M.L.2    Berger, J.M.3
  • 21
    • 0035911969 scopus 로고    scopus 로고
    • Cyclin E uses Cdc6 as a chromatin-associated receptor required for DNA replication
    • Furstenthal L, Kaiser BK, Swanson C, Jackson PK (2001) Cyclin E uses Cdc6 as a chromatin-associated receptor required for DNA replication. J Cell Biol 152:1267-1278.
    • (2001) J Cell Biol , vol.152 , pp. 1267-1278
    • Furstenthal, L.1    Kaiser, B.K.2    Swanson, C.3    Jackson, P.K.4
  • 22
    • 2442528837 scopus 로고    scopus 로고
    • Interaction of the S-phase cyclin Clb5 with an "RXL" docking sequence in the initiator protein Orc6 provides an origin-localized replication control switch
    • Wilmes GM, et al. (2004) Interaction of the S-phase cyclin Clb5 with an "RXL" docking sequence in the initiator protein Orc6 provides an origin-localized replication control switch. Gene Dev 18:981-991.
    • (2004) Gene Dev , vol.18 , pp. 981-991
    • Wilmes, G.M.1
  • 23
    • 0030010591 scopus 로고    scopus 로고
    • Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors
    • Nakayama K, et al. (1996) Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors. Cell 85:707-720.
    • (1996) Cell , vol.85 , pp. 707-720
    • Nakayama, K.1
  • 25
    • 0029948612 scopus 로고    scopus 로고
    • p21 contains independent binding sites for cyclin and cdk2: Both sites are required to inhibit cdk2 kinase activity
    • Fotedar R, et al. (1996) p21 contains independent binding sites for cyclin and cdk2: both sites are required to inhibit cdk2 kinase activity. Oncogene 12:2155-2164.
    • (1996) Oncogene , vol.12 , pp. 2155-2164
    • Fotedar, R.1
  • 26
    • 0028983384 scopus 로고
    • CIP1- related domain to bind cyclin/cdk2 and regulate interactions with E2F
    • CIP1- related domain to bind cyclin/cdk2 and regulate interactions with E2F. Genes Dev 9:1740-1752.
    • (1995) Genes Dev , vol.9 , pp. 1740-1752
    • Zhu, L.1    Harlow, E.2    Dynlacht, B.D.3
  • 27
    • 0029973557 scopus 로고    scopus 로고
    • Identification of a cyclin-cdk2 recognition motif present in substrates and p21-like cyclin-dependent kinase inhibitors
    • Adams PD, et al. (1996) Identification of a cyclin-cdk2 recognition motif present in substrates and p21-like cyclin-dependent kinase inhibitors. Mol Cell Biol 16:6623-6633.
    • (1996) Mol Cell Biol , vol.16 , pp. 6623-6633
    • Adams, P.D.1
  • 28
    • 14844307019 scopus 로고    scopus 로고
    • The structure of cyclin E1/CDK2: Implications for CDK2 activation and CDK2-independent roles
    • Honda R, et al. (2005) The structure of cyclin E1/CDK2: Implications for CDK2 activation and CDK2-independent roles. EMBO J 24:452-463.
    • (2005) EMBO J , vol.24 , pp. 452-463
    • Honda, R.1
  • 30
    • 0028169236 scopus 로고
    • p21-containing cyclin kinases exist in both active and inactive states
    • Zhang H, Hannon GJ, Beach D (1994) p21-containing cyclin kinases exist in both active and inactive states. Genes Dev 8:1750-1758.
    • (1994) Genes Dev , vol.8 , pp. 1750-1758
    • Zhang, H.1    Hannon, G.J.2    Beach, D.3
  • 31
    • 0028986639 scopus 로고
    • Cip1 in muscle and other terminally differentiating cells
    • Cip1 in muscle and other terminally differentiating cells. Science 267:1024-1027.
    • (1995) Science , vol.267 , pp. 1024-1027
    • Parker, S.B.1
  • 32
    • 34548500580 scopus 로고    scopus 로고
    • Cdc6 stability is regulated by the Huwe1 ubiquitin ligase after DNA damage
    • Hall JR, et al. (2007) Cdc6 stability is regulated by the Huwe1 ubiquitin ligase after DNA damage. Mol Biol Cell 18:3340-3350.
    • (2007) Mol Biol Cell , vol.18 , pp. 3340-3350
    • Hall, J.R.1
  • 33
    • 0026860032 scopus 로고
    • Oncogenic signal-induced ability to enter S phase in the absence of anchorage is the mechanism for the growth of transformed NRK cells in soft agar
    • Kume K, et al. (1992) Oncogenic signal-induced ability to enter S phase in the absence of anchorage is the mechanism for the growth of transformed NRK cells in soft agar. New Biol 4:504-511.
    • (1992) New Biol , vol.4 , pp. 504-511
    • Kume, K.1
  • 34
    • 0027024350 scopus 로고
    • Nuclear protein import using digitonin-permeabilized cells
    • Adam SA, Sterne-Marr R, Gerace L (1992) Nuclear protein import using digitonin-permeabilized cells. Methods Enzymol 219:97-110.
    • (1992) Methods Enzymol , vol.219 , pp. 97-110
    • Adam, S.A.1    Sterne-Marr, R.2    Gerace, L.3


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