Trp359 regulates flavin thermodynamics and coenzyme selectivity in Mycobacterium tuberculosis FprA

Biochemical Journal

Volumn 411, Issue 3, 2008, Pages 563-570

  Neeli, Rajasekhar ^a   Sabri, Muna ^a   McLean, Kirsty J ^a   Dunford, Adrian J ^a   Scrutton, Nigel S ^a   Leys, David ^a   Munro, Andrew W ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Adrenodoxin reductase; Coenzyme selectivity; Electron transfer; Flavoprotein reductase A; Mycobacterium tuberculosis

Indexed keywords

BACTERIA; CATALYST ACTIVITY; COENZYMES; ELECTRON TRANSITIONS;

ADRENODOXIN REDUCTASE; COENZYME SELECTIVITY; FLAVOPROTEIN REDUCTASE A; MYCOBACTERIUM TUBERCULOSIS;

ENZYME ACTIVITY;

CYTOCHROME B5 REDUCTASE; CYTOCHROME P450; FERREDOXIN NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE REDUCTASE; FLAVINE ADENINE NUCLEOTIDE; FLAVOPROTEIN REDUCTASE A; OXIDOREDUCTASE; QUERCETIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SEMIQUINONE; TRYPTOPHAN; FPRA PROTEIN, M TUBERCULOSIS; RIBOFLAVIN DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; COENZYME; FLUORESCENCE; MUTANT; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PH ELECTRODE; PHYLOGENY; PRIORITY JOURNAL; PROTEIN EXPRESSION; REDUCTION; STEADY STATE; THERMODYNAMICS; ULTRAVIOLET SPECTROSCOPY; WILD TYPE; AMINO ACID SEQUENCE; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; ENZYMOLOGY; GENETICS; HUMAN; KINETICS; METABOLISM; MOLECULAR GENETICS; MUTATION; NUCLEOTIDE SEQUENCE; PROTEIN TERTIARY STRUCTURE; SEQUENCE ALIGNMENT; SPECTROPHOTOMETRY;

MAMMALIA; MYCOBACTERIUM TUBERCULOSIS;

AMINO ACID SEQUENCE; ANIMALS; COENZYMES; CONSERVED SEQUENCE; FLAVINS; HUMANS; KINETICS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; MYCOBACTERIUM TUBERCULOSIS; NADH, NADPH OXIDOREDUCTASES; PHYLOGENY; PROTEIN STRUCTURE, TERTIARY; SEQUENCE ALIGNMENT; SPECTROPHOTOMETRY; THERMODYNAMICS; TRYPTOPHAN;

EID: 42449124751     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20071298     Document Type: Article

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