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Volumn 51, Issue 4, 2008, Pages 402-409

Effects of antihypertensive drugs on capillary rarefaction in spontaneously hypertensive rats: Intravital microscopy and histologic analysis

Author keywords

blocker; ACE inhibitor; AT1 receptor antagonist; Calcium channel blocker; Capillary rarefaction; Intravital capillaroscopy; SHR

Indexed keywords

ATENOLOL; ENALAPRIL; LOSARTAN; NIFEDIPINE;

EID: 42449102706     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/FJC.0b013e3181673bc5     Document Type: Article
Times cited : (34)

References (49)
  • 1
    • 0344718782 scopus 로고    scopus 로고
    • World Health Organization (WHO)/International Society of Hypertension (ISH) statement on management of hypertension
    • Whitworth JA. 2003 World Health Organization (WHO)/International Society of Hypertension (ISH) statement on management of hypertension. J Hypertens. 2003;21:1983-1992.
    • (2003) J Hypertens , vol.2003 , Issue.21 , pp. 1983-1992
    • Whitworth, J.A.1
  • 2
    • 33646787126 scopus 로고    scopus 로고
    • Mechanisms of target organ damage caused by hypertension: Therapeutic potential
    • Cohuet G, Struijker-Boudier H. Mechanisms of target organ damage caused by hypertension: therapeutic potential. Pharmacol Ther. 2006;111: 81-98.
    • (2006) Pharmacol Ther , vol.111 , pp. 81-98
    • Cohuet, G.1    Struijker-Boudier, H.2
  • 3
    • 0032853121 scopus 로고    scopus 로고
    • Microcirculation and arterial hypertension
    • Vicaut E. Microcirculation and arterial hypertension. Drugs. 1999;58: 1-10.
    • (1999) Drugs , vol.58 , pp. 1-10
    • Vicaut, E.1
  • 5
    • 0032890953 scopus 로고    scopus 로고
    • Structural skin capillary rarefaction in essential hypertension
    • Antonios TF, Singer DR, Markandu ND, et al. Structural skin capillary rarefaction in essential hypertension. Hypertension. 1999;33:998-1001.
    • (1999) Hypertension , vol.33 , pp. 998-1001
    • Antonios, T.F.1    Singer, D.R.2    Markandu, N.D.3
  • 6
    • 33646118227 scopus 로고    scopus 로고
    • Increased skin capillary density in treated essential hypertensive patients
    • Debbabi H, Uzan L, Mourad JJ, et al. Increased skin capillary density in treated essential hypertensive patients. Am J Hypertens. 2006;19: 477-483.
    • (2006) Am J Hypertens , vol.19 , pp. 477-483
    • Debbabi, H.1    Uzan, L.2    Mourad, J.J.3
  • 7
    • 0026600669 scopus 로고
    • Reactivity of small blood vessels in hypertension: Relation with structural changes. State of the art lecture
    • Schiffrin EL. Reactivity of small blood vessels in hypertension: relation with structural changes. State of the art lecture. Hypertension. 1992;19: II1-9.
    • (1992) Hypertension , vol.19
    • Schiffrin, E.L.1
  • 8
    • 33751076238 scopus 로고    scopus 로고
    • Hypertension: A disease of the microcirculation?
    • Feihl F, Liaudet L, Waeber B, et al. Hypertension: a disease of the microcirculation? Hypertension. 2006;48:1012-1017.
    • (2006) Hypertension , vol.48 , pp. 1012-1017
    • Feihl, F.1    Liaudet, L.2    Waeber, B.3
  • 9
    • 0024557970 scopus 로고
    • Microvascular rarefaction and tissue vascular resistance in hypertension
    • Greene AS, Tonellato PJ, Lui J, et al. Microvascular rarefaction and tissue vascular resistance in hypertension. Am J Physiol. 1989;256:H126-31.
    • (1989) Am J Physiol , vol.256
    • Greene, A.S.1    Tonellato, P.J.2    Lui, J.3
  • 10
    • 33748053688 scopus 로고    scopus 로고
    • Importance of improving tissue perfusion during treatment of hypertension
    • Levy B. Importance of improving tissue perfusion during treatment of hypertension. J Hypertens Suppl. 2006;24:S6-9.
    • (2006) J Hypertens Suppl , vol.24
    • Levy, B.1
  • 12
    • 0035822604 scopus 로고    scopus 로고
    • Microcirculation in hypertension: A new target for treatment?
    • Levy BI, Ambrosio G, Pries AR, et al. Microcirculation in hypertension: a new target for treatment? Circulation. 2001;104:735-740.
    • (2001) Circulation , vol.104 , pp. 735-740
    • Levy, B.I.1    Ambrosio, G.2    Pries, A.R.3
  • 13
    • 0028928266 scopus 로고
    • Hypertension and the vasculature: Arterioles and the myogenic response
    • Izzard AS, Heagerty AM. Hypertension and the vasculature: arterioles and the myogenic response. J Hypertens. 1995;13:1-4.
    • (1995) J Hypertens , vol.13 , pp. 1-4
    • Izzard, A.S.1    Heagerty, A.M.2
  • 14
    • 0035569049 scopus 로고    scopus 로고
    • Impaired skin capillary recruitment in essential hypertension is caused by both functional and structural capillary rarefaction
    • Serne EH, Gans RO, ter Maaten JC, et al. Impaired skin capillary recruitment in essential hypertension is caused by both functional and structural capillary rarefaction. Hypertension. 2001;38:238-242.
    • (2001) Hypertension , vol.38 , pp. 238-242
    • Serne, E.H.1    Gans, R.O.2    ter Maaten, J.C.3
  • 15
    • 0032702004 scopus 로고    scopus 로고
    • Rarefaction of skin capillaries in borderline essential hypertension suggests an early structural abnormality
    • Antonios TF, Singer DR, Markandu ND, et al. Rarefaction of skin capillaries in borderline essential hypertension suggests an early structural abnormality. Hypertension. 1999;34:655-658.
    • (1999) Hypertension , vol.34 , pp. 655-658
    • Antonios, T.F.1    Singer, D.R.2    Markandu, N.D.3
  • 16
    • 0030949484 scopus 로고    scopus 로고
    • Impaired microvascular dilatation and capillary rarefaction in young adults with a predisposition to high blood pressure
    • Noon JP, Walker BR, Webb DJ, et al. Impaired microvascular dilatation and capillary rarefaction in young adults with a predisposition to high blood pressure. J Clin Invest. 1997;99:1873-1879.
    • (1997) J Clin Invest , vol.99 , pp. 1873-1879
    • Noon, J.P.1    Walker, B.R.2    Webb, D.J.3
  • 17
    • 0033404645 scopus 로고    scopus 로고
    • Visualization of dermal blood vessels- capillaroscopy
    • Hern S, Mortimer PS. Visualization of dermal blood vessels- capillaroscopy. Clin Exp Dermatol. 1999;24:473-478.
    • (1999) Clin Exp Dermatol , vol.24 , pp. 473-478
    • Hern, S.1    Mortimer, P.S.2
  • 18
    • 0037242152 scopus 로고    scopus 로고
    • Structural and functional changes of the microcirculation in hypertension: Influence of pharmacological therapy]
    • Agabiti-Rosei E. [Structural and functional changes of the microcirculation in hypertension: influence of pharmacological therapy]. Drugs. 2003;63:19-29.
    • (2003) Drugs , vol.63 , pp. 19-29
    • Agabiti-Rosei, E.1
  • 19
    • 33748056852 scopus 로고    scopus 로고
    • Is hypertension a tissue perfusion disorder? Implications for renal and myocardial perfusion
    • Mourad JJ, Laville M. Is hypertension a tissue perfusion disorder? Implications for renal and myocardial perfusion. J Hypertens Suppl. 2006; 24:S10-16.
    • (2006) J Hypertens Suppl , vol.24
    • Mourad, J.J.1    Laville, M.2
  • 20
    • 0035851219 scopus 로고    scopus 로고
    • Proangiogenic effect of angiotensin-converting enzyme inhibition is mediated by the bradykinin B(2) receptor pathway
    • Silvestre JS, Bergaya S, Tamarat R, et al. Proangiogenic effect of angiotensin-converting enzyme inhibition is mediated by the bradykinin B(2) receptor pathway. Circ Res. 2001;89:678-683.
    • (2001) Circ Res , vol.89 , pp. 678-683
    • Silvestre, J.S.1    Bergaya, S.2    Tamarat, R.3
  • 21
    • 11144237722 scopus 로고    scopus 로고
    • Dual effect of angiotensin-converting enzyme inhibition on angiogenesis in type 1 diabetic mice
    • Ebrahimian TG, Tamarat R, Clergue M, et al. Dual effect of angiotensin-converting enzyme inhibition on angiogenesis in type 1 diabetic mice. Arterioscler Thromb Vasc Biol. 2005;25:65-70.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 65-70
    • Ebrahimian, T.G.1    Tamarat, R.2    Clergue, M.3
  • 22
    • 0030638718 scopus 로고    scopus 로고
    • Blockade of bradykinin B2 receptors prevents the increase in capillary density induced by chronic angiotensin-converting enzyme inhibitor treatment in stroke-prone spontaneously hypertensive rats
    • Gohlke P, Kuwer I, Schnell A, et al. Blockade of bradykinin B2 receptors prevents the increase in capillary density induced by chronic angiotensin-converting enzyme inhibitor treatment in stroke-prone spontaneously hypertensive rats. Hypertension. 1997;29:478-482.
    • (1997) Hypertension , vol.29 , pp. 478-482
    • Gohlke, P.1    Kuwer, I.2    Schnell, A.3
  • 23
    • 0025148824 scopus 로고
    • Estimation of surface area and length with the orientator
    • Mattfeldt T, Mall G, Gharehbaghi H, et al. Estimation of surface area and length with the orientator. J Microsc. 1990;159:301-117.
    • (1990) J Microsc , vol.159 , pp. 301-117
    • Mattfeldt, T.1    Mall, G.2    Gharehbaghi, H.3
  • 24
    • 84985274513 scopus 로고
    • Orthogonal triplet probes: An efficient method for unbiased estimation of length and surface of objects with unknown orientation in space
    • Mattfeldt T, Mobius HJ, Mall G. Orthogonal triplet probes: an efficient method for unbiased estimation of length and surface of objects with unknown orientation in space. J Microsc. 1985;139:279-289.
    • (1985) J Microsc , vol.139 , pp. 279-289
    • Mattfeldt, T.1    Mobius, H.J.2    Mall, G.3
  • 25
    • 0016170686 scopus 로고
    • Observation of a decreased number of small arterioles in spontaneously hypertensive rats
    • Hutchins PM, Darnell AE. Observation of a decreased number of small arterioles in spontaneously hypertensive rats. Circ Res. 1974;24:1161-1165.
    • (1974) Circ Res , vol.24 , pp. 1161-1165
    • Hutchins, P.M.1    Darnell, A.E.2
  • 26
    • 0019614858 scopus 로고
    • Microvascular rarefaction in spontaneously hypertensive rat cremaster muscle
    • Chen, II, Prewitt RL, Dowell RF. Microvascular rarefaction in spontaneously hypertensive rat cremaster muscle. Am J Physiol. 1981; 241:H306-310.
    • (1981) Am J Physiol , vol.241
    • Chen, I.1    Prewitt, R.L.2    Dowell, R.F.3
  • 27
    • 0024272492 scopus 로고
    • Microcirculatory changes in cremaster muscle during early spontaneous hypertension in the rat
    • Struyker-Boudier HA le Noble JL, Slaaf DW, et al. Microcirculatory changes in cremaster muscle during early spontaneous hypertension in the rat. J Hypertens Suppl. 1988;6:S185-187.
    • (1988) J Hypertens Suppl , vol.6
    • Struyker-Boudier, H.A.1    le Noble, J.L.2    Slaaf, D.W.3
  • 28
    • 0020172485 scopus 로고
    • Development of microvascular rarefaction in the spontaneously hypertensive rat
    • Prewitt RL, Chen, II, Dowell R. Development of microvascular rarefaction in the spontaneously hypertensive rat. Am J Physiol. 1982; 243:H243-251.
    • (1982) Am J Physiol , vol.243
    • Prewitt, R.L.1    Chen, I.2    Dowell, R.3
  • 29
    • 0141928146 scopus 로고    scopus 로고
    • Training-induced, pressure-lowering effect in SHR: Wide effects on circulatory profile of exercised and nonexercised muscles
    • Melo RM, Martinho E Jr, Michelini LC. Training-induced, pressure-lowering effect in SHR: wide effects on circulatory profile of exercised and nonexercised muscles. Hypertension. 2003;42:851-857.
    • (2003) Hypertension , vol.42 , pp. 851-857
    • Melo, R.M.1    Martinho Jr, E.2    Michelini, L.C.3
  • 30
    • 0022312826 scopus 로고
    • Exercise-induced myocardial capillary growth in the spontaneously hypertensive rat
    • Crisman RP, Rittman B, Tomanek RJ. Exercise-induced myocardial capillary growth in the spontaneously hypertensive rat. Microvasc Res. 1985;30:185-194.
    • (1985) Microvasc Res , vol.30 , pp. 185-194
    • Crisman, R.P.1    Rittman, B.2    Tomanek, R.J.3
  • 31
    • 34250333351 scopus 로고    scopus 로고
    • Effects of angiotensin-converting enzyme inhibitor and exercise training on exercise capacity and skeletal muscle
    • Minami N, Li Y, Guo Q, et al. Effects of angiotensin-converting enzyme inhibitor and exercise training on exercise capacity and skeletal muscle. J Hypertens. 2007;25:1241-1248.
    • (2007) J Hypertens , vol.25 , pp. 1241-1248
    • Minami, N.1    Li, Y.2    Guo, Q.3
  • 32
    • 0024506357 scopus 로고
    • Effects of chronic ACE inhibition on cardiac hypertrophy and coronary vascular reserve in spontaneously hypertensive rats with developed hypertension
    • Clozel JP, Kuhn H, Hefti F. Effects of chronic ACE inhibition on cardiac hypertrophy and coronary vascular reserve in spontaneously hypertensive rats with developed hypertension. J Hypertens. 1989;7:267-275.
    • (1989) J Hypertens , vol.7 , pp. 267-275
    • Clozel, J.P.1    Kuhn, H.2    Hefti, F.3
  • 33
    • 0027457637 scopus 로고
    • Spirapril prevents left ventricular hypertrophy, decreases myocardial damage and promotes angiogenesis in spontaneously hypertensive rats
    • Olivetti G, Cigola E, Lagrasta C, et al. Spirapril prevents left ventricular hypertrophy, decreases myocardial damage and promotes angiogenesis in spontaneously hypertensive rats. J Cardiovasc Pharmacol. 1993;21:362-370.
    • (1993) J Cardiovasc Pharmacol , vol.21 , pp. 362-370
    • Olivetti, G.1    Cigola, E.2    Lagrasta, C.3
  • 34
    • 0026630420 scopus 로고
    • Effect of early onset angiotensin converting enzyme inhibition on myocardial capillaries
    • Unger T, Mattfeldt T, Lamberty V, et al. Effect of early onset angiotensin converting enzyme inhibition on myocardial capillaries. Hypertension. 1992;20:478-482.
    • (1992) Hypertension , vol.20 , pp. 478-482
    • Unger, T.1    Mattfeldt, T.2    Lamberty, V.3
  • 35
    • 0034109905 scopus 로고    scopus 로고
    • The effect of treatment with low dose ACE inhibitor and/or diuretic on coronary microvasculature in stroke-prone spontaneously hypertensive rats
    • Rakusan K, Cicutti N, Maurin A, et al. The effect of treatment with low dose ACE inhibitor and/or diuretic on coronary microvasculature in stroke-prone spontaneously hypertensive rats. Microvasc Res. 2000;59: 243-254.
    • (2000) Microvasc Res , vol.59 , pp. 243-254
    • Rakusan, K.1    Cicutti, N.2    Maurin, A.3
  • 36
    • 1642452756 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme inhibition and angiogenesis in myocardium of obese Zucker rats
    • Toblli JE, Cao G, DeRosa G, et al. Angiotensin-converting enzyme inhibition and angiogenesis in myocardium of obese Zucker rats. Am J Hypertens. 2004;17:172-180.
    • (2004) Am J Hypertens , vol.17 , pp. 172-180
    • Toblli, J.E.1    Cao, G.2    DeRosa, G.3
  • 37
    • 0023257146 scopus 로고
    • Systemic and regional hemodynamic profile of five angiotensin I converting enzyme inhibitors in the spontaneously hypertensive rat
    • Richer C, Doussau MP, Giudicelli JF. Systemic and regional hemodynamic profile of five angiotensin I converting enzyme inhibitors in the spontaneously hypertensive rat. Am J Cardiol. 1987;59:12D-17D.
    • (1987) Am J Cardiol , vol.59
    • Richer, C.1    Doussau, M.P.2    Giudicelli, J.F.3
  • 38
    • 12144256335 scopus 로고    scopus 로고
    • Update on the role of the AT2 receptor
    • Carey RM. Update on the role of the AT2 receptor. Curr Opin Nephrol Hypertens. 2005;14:67-71.
    • (2005) Curr Opin Nephrol Hypertens , vol.14 , pp. 67-71
    • Carey, R.M.1
  • 39
    • 34247844373 scopus 로고    scopus 로고
    • Angiotensin II induces angiogenesis in the hypoxic adult mouse heart in vitro through an AT2-B2 receptor pathway
    • Munk VC, Sanchez de Miguel L, Petrimpol M, et al. Angiotensin II induces angiogenesis in the hypoxic adult mouse heart in vitro through an AT2-B2 receptor pathway. Hypertension. 2007;49:1178-1185.
    • (2007) Hypertension , vol.49 , pp. 1178-1185
    • Munk, V.C.1    Sanchez de Miguel, L.2    Petrimpol, M.3
  • 40
    • 0031818850 scopus 로고    scopus 로고
    • Microvasculature in angiotensin II-dependent cardiac hypertrophy in the rat
    • Sabri A, Samuel JL, Marotte F, et al. Microvasculature in angiotensin II-dependent cardiac hypertrophy in the rat. Hypertension. 1998;32:371-375.
    • (1998) Hypertension , vol.32 , pp. 371-375
    • Sabri, A.1    Samuel, J.L.2    Marotte, F.3
  • 41
    • 0028261960 scopus 로고
    • Comparative effects of chronic angiotensin-converting enzyme inhibition and angiotensin II type 1 receptor blockade on cardiac remodeling after myocardial infarction in the rat
    • Schieffer B, Wirger A, Meybrunn M, et al. Comparative effects of chronic angiotensin-converting enzyme inhibition and angiotensin II type 1 receptor blockade on cardiac remodeling after myocardial infarction in the rat. Circulation. 1994;89:2273-2282.
    • (1994) Circulation , vol.89 , pp. 2273-2282
    • Schieffer, B.1    Wirger, A.2    Meybrunn, M.3
  • 42
    • 0027570436 scopus 로고
    • Similarities and differences between calcium antagonists: Pharmacological aspects
    • van Zwieten PA, Pfaffendorf M. Similarities and differences between calcium antagonists: pharmacological aspects. J Hypertens Suppl. 1993; 11:S3-11.
    • (1993) J Hypertens Suppl , vol.11
    • van Zwieten, P.A.1    Pfaffendorf, M.2
  • 43
    • 33746590315 scopus 로고    scopus 로고
    • Microcirculation in rat soleus muscle after eccentric exercise: The effect of nifedipine
    • Heap SJ, Fulgenzi GL, Hudlicka O. Microcirculation in rat soleus muscle after eccentric exercise: the effect of nifedipine. Eur J Appl Physiol. 2006; 97:687-694.
    • (2006) Eur J Appl Physiol , vol.97 , pp. 687-694
    • Heap, S.J.1    Fulgenzi, G.L.2    Hudlicka, O.3
  • 44
    • 0026349595 scopus 로고
    • What makes blood vessels grow?
    • Hudlicka O. What makes blood vessels grow? J Physiol. 1991;444:1-24.
    • (1991) J Physiol , vol.444 , pp. 1-24
    • Hudlicka, O.1
  • 45
    • 0024599070 scopus 로고
    • Development of blood pressure in spontaneously hypertensive rats after withdrawal of long-term treatment related to vascular structure
    • Christensen KL, Jespersen LT, Mulvany MJ. Development of blood pressure in spontaneously hypertensive rats after withdrawal of long-term treatment related to vascular structure. J Hypertens. 1989;7:83-90.
    • (1989) J Hypertens , vol.7 , pp. 83-90
    • Christensen, K.L.1    Jespersen, L.T.2    Mulvany, M.J.3
  • 46
    • 0346524356 scopus 로고
    • Effects of a beta-blocker or a converting enzyme inhibitor on resistance arteries in essential hypertension
    • Schiffrin EL, Deng LY, Larochelle P. Effects of a beta-blocker or a converting enzyme inhibitor on resistance arteries in essential hypertension. Hypertension. 1994;23:83-91.
    • (1994) Hypertension , vol.23 , pp. 83-91
    • Schiffrin, E.L.1    Deng, L.Y.2    Larochelle, P.3
  • 47
    • 0028929787 scopus 로고
    • Effect of antihypertensive treatment on small arteries of patients with previously untreated essential hypertension
    • Thybo NK, Stephens N, Cooper A, et al. Effect of antihypertensive treatment on small arteries of patients with previously untreated essential hypertension. Hypertension. 1995;25:474-481.
    • (1995) Hypertension , vol.25 , pp. 474-481
    • Thybo, N.K.1    Stephens, N.2    Cooper, A.3
  • 48
    • 0035019959 scopus 로고    scopus 로고
    • Vasodilatation, not hypotension, improves resistance vessel design during treatment of essential hypertension: A literature survey
    • Christensen KL, Mulvany MJ. Vasodilatation, not hypotension, improves resistance vessel design during treatment of essential hypertension: a literature survey. J Hypertens. 2001;19:1001-1006.
    • (2001) J Hypertens , vol.19 , pp. 1001-1006
    • Christensen, K.L.1    Mulvany, M.J.2
  • 49
    • 0029916051 scopus 로고    scopus 로고
    • Captopril inhibits angiogenesis and slows the growth of experimental tumors in rats
    • Volpert OV, Ward WF, Lingen MW, et al. Captopril inhibits angiogenesis and slows the growth of experimental tumors in rats. J Clin Invest. 1996; 98:671-679.
    • (1996) J Clin Invest , vol.98 , pp. 671-679
    • Volpert, O.V.1    Ward, W.F.2    Lingen, M.W.3


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