CT colonography and computer-aided detection: Effect of false-positive results on reader specificity and reading efficiency in a low-prevalence screening population

Radiology

Volumn 247, Issue 1, 2008, Pages 133-140

  Taylor, Stuart A ^a   Greenhalgh, Rebecca ^a   Ilangovan, Rajapandian ^b   Tam, Emily ^b   Sahni, Vikram A ^b   Burling, David ^b   Zhang, Jie ^c   Bassett, Paul ^b   Pickhardt, Perry J ^d   Halligan, Steve ^a  

^a UNIVERSITY COLLEGE HOSPITAL   (United Kingdom)

^b ST MARK S HOSPITAL   (United Kingdom)

^c CAPITAL MEDICAL UNIVERSITY   (China)

^d UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BARIUM; DIATRIZOATE; MEGLUMINE DIATRIZOATE;

ADULT; ARTICLE; CLINICAL ARTICLE; COMPUTED TOMOGRAPHIC COLONOGRAPHY; COMPUTER AIDED DESIGN; CONTROLLED STUDY; DIAGNOSTIC IMAGING; FEMALE; HUMAN; INTESTINE POLYP; MALE; PREVALENCE; PRIORITY JOURNAL; RECEIVER OPERATING CHARACTERISTIC; SENSITIVITY AND SPECIFICITY; ADENOMATOUS POLYP; AGED; COLON POLYP; COMPUTER ASSISTED DIAGNOSIS; LABORATORY DIAGNOSIS; MIDDLE AGED; OBSERVER VARIATION; RADIOGRAPHY; ROC CURVE;

ADENOMATOUS POLYPS; ADULT; AGED; AGED, 80 AND OVER; COLONIC POLYPS; COLONOGRAPHY, COMPUTED TOMOGRAPHIC; FALSE POSITIVE REACTIONS; FEMALE; HUMANS; MALE; MIDDLE AGED; OBSERVER VARIATION; RADIOGRAPHIC IMAGE INTERPRETATION, COMPUTER-ASSISTED; ROC CURVE; SENSITIVITY AND SPECIFICITY;

EID: 42449098496     PISSN: 00338419     EISSN: 15271315     Source Type: Journal    
DOI: 10.1148/radiol.2471070816     Document Type: Article

References (21)

1. Freer TW, Ulissey MJ. Screening mammography with computer-aided detection: prospective study of 12,860 patients in a community breast center. Radiology 2001;220:781-786.
2. Warren Burhenne LJ, Wood SA, D'Orsi CJ, et al. Potential contribution of computer-aided detection to the sensitivity of screening mammography. Radiology 2000;215:554-562.
3. Summers RM, Yao J, Pickhardt PJ, et al. Computed tomographic virtual colonoscopy computer-aided polyp detection in a screening population. Gastroenterology 2005;129:1832-1844.
4. Yoshida H, Nappi J, MacEneaney P, Rubin DT, Dachman AH. Computer-aided diagnosis scheme for detection of polyps at CT colonography. RadioGraphics 2002;22:963-979.
5. Yoshida H, Masutani Y, MacEneaney P, Rubin DT, Dachman AH. Computerized detection of colonic polyps at CT colonography on the basis of volumetric features: pilot study. Radiology 2002;222:327-336.
6. Taylor SA, Halligan S, Burling D, et al. Computer-assisted reader software versus expert reviewers for polyp detection on CT colonography. AJR Am J Roentgenol 2006;186:696-702.
7. Halligan S, Altman DG, Mallett S, et al. Computed tomographic colonography: assessment of radiologist performance with and without computer-aided detection. Gastroenterology 2006;131:1690-1699.
8. Summers RM, Jerebko AK, Franaszek M, Malley JD, Johnson CD. Colonic polyps: complementary role of computer-aided detection in CT colonography. Radiology 2002;225:391-399.
9. Pickhardt PJ, Taylor AJ, Kim DH, Reichelderfer M, Gopal DV, Pfau PR. Screening for colorectal neoplasia with CT colonography: initial experience from the 1st year of coverage by third-party payers. Radiology 2006;241:417-425.
10. Sonnenberg A, Delco F, Bauerfeind P. Is virtual colonoscopy a cost-effective option to screen for colorectal cancer? Am J Gastroenterol 1999;94:2268-2274.
11. Vijan S, Hwang I, Inadomi J, et al. The cost-effectiveness of CT colonography in screening for colorectal neoplasia. Am J Gastroenterol 2007;102:380-390.
12. Hukkinen K, Vehmas T, Pamilo M, Kivisaari L. Effect of computer-aided detection on mammographic performance: experimental study on readers with different levels of experience. Acta Radiol 2006;47:257-263.
13. Halligan S, Taylor SA, Dehmeshki J, et al. Computer-assisted detection for CT colonography: external validation. Clin Radiol 2006;61:758-763.
14. Zalis ME, Barish MA, Choi JR, et al. CT colonography reporting and data system: a consensus proposal. Radiology 2005;236:3-9.
15. Williams RL. A note on robust variance estimation for cluster-correlated data. Biometrics 2000;56:645-646.
16. Bogoni L, Cathier P, Dundar M, et al. Computer-aided detection (CAD) for CT colonography: a tool to address a growing need. Br J Radiol 2005;78(spec issue 1):S57-S62.
17. Nappi J, Yoshida H. Feature-guided analysis for reduction of false positives in CAD of polyps for computed tomographic colonography. Med Phys 2003;30:1592-1601.
18. Mani A, Napel S, Paik DS, et al. Computed tomography colonography: feasibility of computer-aided polyp detection in a "first reader" paradigm. J Comput Assist Tomogr 2004;28:318-326.
19. Dehmeshki J, Halligan S, Taylor SA, et al. Computer assisted detection software for CT colonography: effect of sphericity filter on performance characteristics for patients with and without fecal tagging. Eur Radiol 2007;17:662-668.
20. Taylor SA, Halligan S, Slater A, et al. Polyp detection with CT colonography: primary 3D endoluminal analysis versus primary 2D transverse analysis with computer-assisted reader software. Radiology 2006;239:759-767.
21. Wagner RF. An overview of contemporary ROC methodology in medical imaging and computer assist modalities. http://www.fda.gov/ohrms/dockets/ac/04/slides/ 4024s1-01-ROC-TUTORIAL.PPT. Published March 6, 2001. Accessed January 3, 2007.