Systematic of psychiatric disorders between categorical and dimensional approaches: Kraepelin's dichotomy and beyond

European Archives of Psychiatry and Clinical Neuroscience

Volumn 258, Issue SUPPL. 2, 2008, Pages 48-73

  Möller, Hans Jürgen ^a  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

Author keywords

Categorical approach; Classification; Dimensional approach; Kraepelin dichotomy; Syndromatology; Systematics of psychiatric disorders

Indexed keywords

CHRONIC DISEASE; CONFERENCE PAPER; DEVELOPMENT; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; DISEASE CLASSIFICATION; FOLLOW UP; GENETICS; INTERNATIONAL CLASSIFICATION OF DISEASES; KRAEPELIN DICHOTOMY; MEDICAL RESEARCH; MENTAL DISEASE; MOOD DISORDER; NEUROCHEMISTRY; NEUROIMAGING; PRIORITY JOURNAL; REMISSION; SCHIZOPHRENIA; VALIDITY;

DIAGNOSIS, DIFFERENTIAL; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; HUMANS; INTERNATIONAL CLASSIFICATION OF DISEASES; MENTAL DISORDERS; NEUROBIOLOGY; PSYCHIATRY; PSYCHOTIC DISORDERS; SCHIZOPHRENIA;

EID: 42449091794     PISSN: 09401334     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00406-008-2004-3     Document Type: Conference Paper

References (296)

1. Abi-Dargham A (2004) Do we still believe in the dopamine hypothesis? New data bring new evidence. Int J Neuropsychopharmacol 7(Suppl 1):S1-S5
2. Akiskal H (2005) The bipolar spectrum: history, description, boundaries, and validity. In: Kasper S, Hirschfeld RMA (eds) Handbook of bipolar disorder. Taylor & Francis, London, pp 49-68
3. Akiskal H (2007) The interface of affective and schizophrenic disorders: a cross between two spectra? In: Marneros A, Akiskal H (eds) The overlap of affective and schizophrenic spectra. Cambridge University Press, Cambridge, pp 277-291
4. Akiskal HS (1999) Bipolar disorder: outcome. New Engl J Med 341:1861-1862
5. Akiskal HS (2002) The bipolar spectrum-the shaping of a new paradigm in psychiatry. Curr Psychiatry Rep 4:1-3
6. Allardyce J, McCreadie RG, Morrison G, van Os J (2007) Do symptom dimensions or categorical diagnoses best discriminate between known risk factors for psychosis? Soc Psychiatry Psychiatr Epidemiol 42:429-437
7. American Psychiatric Association (APA) (1980) Diagnostic and statistical manual of mental disorders, DSM-III, 3rd edn. APA, Washington
8. American Psychiatric Association (APA) (1988) Diagnostic and statistical manual of mental disorders, DSM-III-R, 3rd edn. APA, Washington
9. American Psychiatric Association (APA) (1994) Diagnostic and statistical manual of mental disorders, (DSM-IV), 4th edn. APA, Washington
10. Andreasen NC, Olsen S (1982) Negative vs. positive schizophrenia. Definition and validation. Arch Gen Psychiatry 39:789-794
11. Angst J (2002) Historical aspects of the dichotomy between manic-depressive disorders and schizophrenia. Schizophr Res 57:5-13
12. Angst J (2002) Historical aspects of the dichotomy between manic-depressive disorders and schizophrenia. Schizophr Res 57:5-13
13. Angst J (2007) Psychiatric diagnoses: the weak component of modern research. World Psychiatry 6:30-31
14. Angst J, Felder W, Lohmeier B (1979) A genetic study on schizoaffective disorders. In: Obiols J, Ballus C, Gonzales Monclus E (eds) Biological psychiatry today. Elsevier/North Holland Biomedical Press, Amsterdam, pp 12-18
15. Angst J, Perris C (1968) Zur Nosologie endogener Depressionen. Arch Psychiatr Nervenkr 219:373-386
16. Angst J, Scharfetter C (1979) Subtypes of schizophrenia and affective disorders from a genetic viewpoint. In: Obiols J, Ballus C, Gonzales Monclus E (eds) Biolgical psychiatry today. Eslevier/North Holland Biomedical Press, Amsterdam, pp 351-357
17. Angst J, Sellaro R, Stassen HH, Gamma A (2005) Diagnostic conversion from depression to bipolar disorders: results of a long-term prospective study of hospital admissions. J Affect Disord 84:149-157
18. Apud JA, Weinberger DR (2007) Treatment of cognitive deficits associated with schizophrenia: potential role of catechol-O-methyltransferase inhibitors. CNS Drugs 21:535-557
19. Arbeitsgemeinschaft für Methodik und Dokumentation in der Psychiatrie (1995) Das AMDP-System. Manual zur Dokumentation psychiatrischer Befunde. 5. umgearb. Aufl. Springer, Berlin
20. Badner JA, Gershon ES (2002) Meta-analysis of whole-genome linkage scans of bipolar disorder and schizophrenia. Mol Psychiatry 7:405-411
21. Baghai TC, Binder EB, Schule C, Salyakina D, Eser D, Lucae S, Zwanzger P, Haberger C, Zill P, Ising M et al (2006) Polymorphisms in the angiotensin-converting enzyme gene are associated with unipolar depression, ACE activity and hypercortisolism. Mol Psychiatry 11:1003-1015
22. Baumann U (1987) Psychiatrische Klassifikation und Interpretation. In: Simhandl C, Berner P, Luccioni H, Alf C (eds) Moderne Psychiatrie. Klassifikationsprobleme in der Psychiatrie. Pukersdorf, Medizinisch- pharmazeutische Verlagsgesellschaft, pp 87-102
23. Baumann U, Stieglitz RD (1983) Testmanual zum AMDP-system. Springer, Berlin
24. Berrettini W (2003) Evidence for shared susceptibility in bipolar disorder and schizophrenia. Am J Med Genet C Semin Med Genet 123:59-64
25. Bleuler E (1950) Dementia praecox or the group of schizophrenias. International University Press, New York
26. Bleuler E (1972) Lehrbuch der Psychiatrie, 12th edn. Springer, Berlin
27. Bleuler M (1972) Die schizophrenen Geistesstörungen im Licht langjähriger Kranken- und Familiengeschichten. Thieme, Stuttgart
28. Bobon D (1983) Foreign adaptions of the AMDP-system. Mod Probl Pharmacopsychiatry 20:19-34
29. Bobon D, Ansseau M (1986) The AMDP-system in clinical psychopharmacology. Pharmacopsychiatry 19:55-57
30. Bobon D, Woggon B (1986) The AMDP-system in clinical psychopharmacology. Br J Psychiatry 148:467-468
31. Bogerts B, Falkai P, Haupts M et al (1990) Post-mortem volume measurement of limbic system and basal ganglia structures in chronic schizophrenics. Schizophr Res 3:295-301
32. Bogerts B, Lieberman J (1993) Neuropathology in the study of psychiatric disease. In: Costa e Silva ACJ, Nadelson CC (eds) International review of psychiatry, 1st edn. American Psychiatric Press, Washington
33. Bonhoeffer K (1912) Die Psychosen im Gefolge von akuten Infektionen, Allgemeinerkrankungen und inneren Erkrankungen. In: Aschaffenburg G (ed) Handbuch der Psychiatrie. Deutike, Leiptig Vienna, pp 1-118
34. Boteva K, Lieberman J (2003) Reconsidering the classification of schizophrenia and manic depressive illness-a critical analysis and new conceptual model. World J Biol Psychiatry 4:81-92
35. Boteva K, Lieberman J (2003) Reconsidering the classification of schizophrenia and manic depressive illness-a critical analysis and new conceptual model. World J Biol Psychiatry 4:81-92
36. Bottlender R, Sato T, Groll C, Jager M, Kunze I, Moller HJ (2003) Negative symptoms in depressed and schizophrenic patients: how do they differ? J Clin Psychiatry 64:954-958
37. Bottlender R, Wegner U, Wittmann J, Strauss A, Möller HJ (1999) Deficit syndromes in schizophrenic patients 15 years after their first hospitalisation: preliminary results of a follow-up study. Eur Arch Psychiatry Clin Neurosci 249(Suppl 4):27-36
38. Braff DL, Freedman R, Schork NJ, Gottesman II (2007) Deconstructing schizophrenia: an overview of the use of endophenotypes in order to understand a complex disorder. Schizophr Bull 33:21-32
39. Bressan RA, Chaves AC, Pilowsky LS, Shirakawa I, Mari JJ (2003) Depressive episodes in stable schizophrenia: crotical evaluation of the DSM-V and ICD-10 diagnostic criteria. Psychiatry Res 117:47-56
40. Brockington IF, Kendell RE, Leff JP (1978) Definitions of schizophrenia: concordance and prediction of outcome. Psychol Med 8:387-398
41. Brockington J (1981) The nosological status of schizoaffective psychosis. In: Perris C, Struwe G, Jansson B (eds) Biological psychiatry, vol 5. Elsevier/North Holland Biomedical Press, Amsterdam, pp 482-485
42. Buchanan RW, Davis M, Goff D, Green MF, Keefe RS, Leon AC, Nuechterlein KH, Laughren T, Levin R, Stover E et al (2005) A summary of the FDA-NIMH-MATRICS workshop on clinical trial design for neurocognitive drugs for schizophrenia. Schizophr Bull 31:5-19
43. Bumke O (1924) Ueber die gegenwärtigen Strömungen in der klinischen Psychiatrie. Münch Med Wochenschr 46:1595-1599
44. Busch H, von Cranach M, Gulbinat W, Renfordt E, Tegeler J (1980) Reliability of the AMDP-system. A preliminary report on a multicentre exercise on the reliability of psychopathological assessment. Acta Psychiatr Scand 62:382-392
45. Cahn W, Hulshoff Pol HE, Bongers M, Schnack HG, Mandl RC, Van Haren NE, Durston S, Koning H, Van Der Linden JA, Kahn RS (2002) Brain morphology in antipsychotic-naive schizophrenia: a study of multiple brain structures. Br J Psychiatry Suppl 43:s66-s72
46. Cahn W, Hulshoff Pol HE, Lems EB, Van Haren NE, Schnack HG, Van Der Linden JA, Schothorst PF, van Engeland H, Kahn RS (2002) Brain volume changes in first-episode schizophrenia: a 1-year follow-up study. Arch Gen Psychiatry 59:1002-1010
47. Cahn W, Van Haren NE, Hulshoff Pol HE, Schnack HG, Caspers E, Laponder DA, Kahn RS (2006) Brain volume changes in the first year of illness and 5-year outcome of schizophrenia. Br J Psychiatry 189:381-382
48. Cairns V, von Zerssen D, Stutte KH, Mombour W (1982) The stability of the symptom groupings in the inpatient multidimensional psychiatric scale (IMPS). J Psychiatr Res 17:19-28
49. Cannon M, Caspi A, Moffitt TE, Harrington H, Taylor A, Murray RM, Poulton R (2002) Evidence for early-childhood, pan-developmental impairment specific to schizophreniform disorder: results from a longitudinal birth cohort. Arch Gen Psychiatry 59:449-456
50. Cannon M, Jones PB, Murray RM (2002) Obstetric complications and schizophrenia: historical and meta-analytic review. Am J Psychiatry 159:1080-1092
51. Cannon TD, Keller MC (2006) Endophenotypes in the genetic analyses of mental disorders. Annu Rev Clin Psychol 2:267-290
52. Cardno AG, Rijsdijk FV, Sham PC, Murray RM, McGuffin P (2002) A twin study of genetic relationships between psychotic symptoms. Am J Psychiatry 159:539-545
53. Carlsson A (1978) Antipsychotic drugs, neurotransmitters, and schizophrenia. Am J Psychiatry 135:165-173
54. Carney MW, Roth M, Garside RF (1965) The diagnosis of depressive syndromes and the prediction of E.C.T. response. Br J Psychiatry 111:659-674
55. Carpenter WT Jr (1994) The deficit syndrome. Am J Psychiatry 151:327-329
56. Carpenter WT (2007) Deconstructing and reconstructing illness syndromes associated with psychosis. World Psychiatry 6:28-29
57. Carpenter WT (2007) Schizophrenia: diagnostic class or domains of pathology. Schizophr Res 33:203
58. Cichon S, Schumacher J, Muller DJ, Hurter M, Windemuth C, Strauch K, Hemmer S, Schulze TG, Schmidt-Wolf G, Albus M et al (2001) A genome screen for genes predisposing to bipolar affective disorder detects a new susceptibility locus on 8q. Hum Mol Genet 10:2933-2944
59. Conus P, Abdel-Baki A, Harrigan S, Lambert M, McGorry PD (2004) Schneiderian first rank symptoms predict poor outcome within first episode manic psychosis. J Affect Disord 81:259-268
60. Cooper JE, Kendell RE, Gurland BJ, Sharpe L, Copeland JRM, Simon R (1972) Psychiatric diagnosis in New York and London. Oxford University, London
61. Corfas G, Roy K, Buxbaum JD (2004) Neuregulin 1-erbB signaling and the molecular/cellular basis of schizophrenia. Nat Neurosci 7:575-580
62. Coryell W, Leon AC, Turvey C, Akiskal HS, Mueller T, Endicott J (2001) The significance of psychotic features in manic episodes: a report from the NIMH collaborative study. J Affect Disord 67:79-88
63. Costa P, McCrae R (1992) Manual for the revised NEO personality inventory (NEO-PI-R) and NEO five-factor inventory (NEO-FFI). Psychological Assessment Resources, Odessa
64. Costello CG (1970) Classification and psychopathology. In: Costello CG (ed) Symptoms of psychopathology. Wiley, New York, pp 1-26
65. Craddock N, O'Donovan MC, Owen MJ (2005) The genetics of schizophrenia and bipolar disorder: dissecting psychosis. J Med Genet 42:193-204
66. Craddock N, O'Donovan MC, Owen MJ (2006) Genes for schizophrenia and bipolar disorder? Implications for psychiatric nosology. Schizophr Bull 32:9-16
67. Craddock N, Owen MJ (2005) The beginning of the end for the Kraepelinian dichotomy. Br J Psychiatry 186:364-366
68. Craddock N, Owen MJ (2007) Rethinking psychosis: the disadvantages of a dichotomous classification now outweigh the advantages. World Psychiatry 6:20-27
69. Craig T, Hwang MY, Bromet EJ (2002) Obsessive-compulsive and panic symptoms in patients with first-admission psychosis. Am J Psychiatry 159:592-598
70. Crow TJ (1985) The two-syndrome concept: origins and current status. Schizophr Bull 11:471-486
71. Crow TJ (1987) Psychosis as a continuum and the virogene concept. Br Med Bull 43:754-767
72. Crow TJ (1990) Nature of the genetic contribution to psychotic illness-a continuum viewpoint. Acta Psychiatr Scand 81:401-408
73. Crow TJ (1990) The continuum of psychosis and its genetic origins. The sixty-fifth Maudsley lecture. Br J Psychiatry 156:788-797
74. Crow TJ (1995) A continuum of psychosis, one human gene, and not much else-the case for homogeneity. Schizophr Res 17:135-145
75. Crow TJ (2006) March 27, 1827 and what happened later-the impact of psychiatry on evolutionary theory. Prog Neuropsychopharmacol Biol Psychiatry 30:785-796
76. Crow TJ (2007) How and why genetic linkage has not solved the problem of psychosis: review and hypothesis. Am J Psychiatry 164:13-21
77. Crow TJ (2007) How and why genetic linkage has not solved the problem of psychosis: review and hypothesis. Am J Psychiatry 164:13-21
78. Den Boer JA, Vahlne JO, Post P, Heck AH, Daubenton F, Olbrich R (2000) Ritanserin as add-on medication to neuroleptic therapy for patients with chronic or subchronic schizophrenia. Hum Psychopharmacol 15:179-189
79. Diebold K, Engel T (1977) Symptomatology, syndromatology, and age of first illness of endogenous depressive and schizophrenic psychoses in relation to secondary or primary diagnoses and sex (author's transl). Nervenarzt 48:130-138
80. Dixon L (1999) Dual diagnosis of substance abuse in schizophrenia: prevalence and impact on outcomes. Schizophr Res Suppl 35:S93-S100
81. Dixon L, Green-Paden L, Delahanty J, Lucksted A, Postrado L, Hall J (2001) Variables associated with disparities in treatment of patients with schizophrenia and comorbid mood and anxiety disorders. Psychiatr Serv 52:1216-1222
82. Dunayevich E, Keck PE Jr (2000) Prevalence and description of psychotic features in bipolar mania. Curr Psychiatry Rep 2:286-290
83. Dutta R, Greene T, Addington J (2007) Biological, life course and cross-cultural studies all point towards the value of dimensional and developmental ratings in the classification of psychosis. Schizophr Bull 33(4):868-876
84. Everitt BS, Gourlay AJ, Kendell RE (1971) An attempt at validation of traditional psychiatric syndromes by cluster analysis. Br J Psychiatry 119:399-412
85. Eysenck HJ (1960) Classification and the problem of diagnosis. In: Eysenck HJ (ed) Handbook of abnormal psychology. Pitman, London, pp 1-31
86. Eysenck HJ (1970) A dimensional system of psychodiagnostics. In: Mahrer AR (ed) New approaches to personality classification. Columbia University Press, New York, pp 169-207
87. Fahrenberg J, Selg H, Hampel R (1978) Das Freiburger Persö nlichkeits-Inventar FPI. Hogrefe, Göttingen Toronto Zürich
88. Falret JP (1851) Marche de la folie. Gaz Hop 24:18-19
89. Feighner JP, Robins E, Guze SB, Woodruff RA Jr, Winokur G, Munoz R (1972) Diagnostic criteria for use in psychiatric research. Arch Gen Psychiatry 26:57-63
90. Fenton WS, McGlashan TH (1989) Testing systems for assessment of negative symptoms in schizophrnenia. Arch Gen Psychiatry 49:236-237
91. First MB (2006) Deconstructing psychosis. http://dsm5org/conference5cfm
92. Fish F (1963) The unitary psychosis-a neurophysiological model. Confin Psychiatr 23:155-170
93. Flor-Henry P, Lind JC, Koles ZJ (2004) A source-imaging (low-resolution electromagnetic tomography) study of the EEGs from unmedicated males with depression. Psychiatry Res 130:191-207
94. Foulds GA, Bedford A (1975) Hierarchy of classes of personal illness. Psychol Med 5:181-192
95. Frodl T, Meisenzahl EM, Zill P, Baghai T, Rujescu D, Leinsinger G, Bottlender R, Schüle C, Zwanzger P, Engel RR et al (2004) Reduced hippocampal volumes associated with the long variant of the serotonin transporter polymorphism in major depression. Arch Gen Psychiatry 61:177-183
96. Frodl T, Schaub A, Banac S, Charypar M, Jäger M, Kummler P, Bottlender R, Zetzsche T, Born C, Leinsinger G et al (2006) Reduced hippocampal volume correlates with executive dysfunctioning in major depression. J Psychiatry Neurosci 31:316-323
97. Gebhardt R, Pietzcker A (1983) Validity of the syndrome scales in the AMDP-system. Arch Psychiatr Nervenkr 233:509-523
98. Gebhardt R, Pietzcker A, Freudenthal K, Langer C (1981) Building syndromes in the AMP-system (author's transl). Arch Psychiatr Nervenkr 231:93-109
99. Goldberg DP, Cooper B, Eastwood MR, Kedward HB, Shepherd M (1970) A standardized psychiatric interview for use in community surveys. Br J Prev Soc Med 24:18-23
100. Goldberg JF, Harrow M, Grossman LS (1995) Course and outcome in bipolar affective disorders: a longitudinal follow-up study. Am J Psychiatry 152:379-385
101. Goldberg TE, Straub RE, Callicott JH, Hariri A, Mattay VS, Bigelow L, Coppola R, Egan MF, Weinberger DR (2006) The G72/G30 gene complex and cognitive abnormalities in schizophrenia. Neuropsychopharmacology 31:2022-2032
102. Goldberg TE, Straub RE, Callicott JH, Hariri A, Mattay VS, Bigelow L, Coppola R, Egan MF, Weinberger DR (2006) The G72/G30 gene complex and cognitive abnormalities in schizophrenia. Neuropsychopharmacology 31:2022-2032
103. Goldschmith RJ (1999) Overview of psychiatric comorbidity. Practical and theoretic considerations. Psychiatr Clin North Am 22:331-349
104. Gray JA, Roth BL (2007) Molecular targets for treating cognitive dysfunction in schizophrenia. Schizophr Bull 33:1100-1119
105. Green EK, Raybould R, Macgregor S, Gordon-Smith K, Heron J, Hyde S, Grozeva D, Hamshere M, Williams N, Owen MJ et al (2005) Operation of the schizophrenia susceptibility gene, neuregulin 1, across traditional diagnostic boundaries to increase risk for bipolar disorder. Arch Gen Psychiatry 62:642-648
106. Griesinger W (1845) Die Pathologie und Therapie der psychischen Krankheiten. Krabbe, Stuttgart
107. Gross G, Huber G, Klosterkötter J (1987) BSABS-Bonner Skala für die Beurteilung von Basissymptomen. Springer, Berlin
108. Grossman LS, Harrow M, Goldberg JF, Fichtner CG (1991) Outcome of schizoaffective disorder at two long-term follow-ups: comparisons with outcome of schizophrenia and affective disorders. Am J Psychiatry 148:1359-1365
109. Guillin O, Abi-Dargham A, Laruelle M (2007) Neurobiology of dopamine in schizophrenia. Int Rev Neurobiol 78:1-39
110. Guislain J (1833) Traite des phrenopathies ou doctrine nouvelle des maladies mentales. Etablissement Enceclopedique, Brüssel
111. Häfner H, Maurer K, Trendler G, an der HW, Schmidt M (2005) The early course of schizophrenia and depression*. Eur Arch Psychiatry Clin Neurosci 255:167-173
112. Harding CM, Brooks GW, Ashikaga T, Strauss JS, Breier A (1987) The Vermont longitudinal study of persons with severe mental illness, II: long-term outcome of subjects who retrospectively met DSM-III criteria for schizophrenia. Am J Psychiatry 144:727-735
113. Harrison G, Hopper K, Craig T, Laska E, Siegel C, Wanderling J, Dube KC, Ganev K, Giel R, an der HW et al (2001) Recovery from psychotic illness: a 15- and 25-year international follow-up study. Br J Psychiatry 178:506-517
114. Harrow M, Grossman LS, Herbener ES, Davies EW (2000) Ten-year outcome: patients with schizoaffective disorders, schizophrenia, affective disorders and mood-incongruent psychotic symptoms. Br J Psychiatry 177:421-426
115. Hegerl U, Juckel G, Muller-Schubert A, Pietzcker A, Gaebel W (1995) Schizophrenics with small P300: a subgroup with a neurodevelopmental disturbance and a high risk for tardive dyskinesia? Acta Psychiatr Scand 91:120-125
116. Heinrichs RW (2004) Meta-analysis and the science of schizophrenia: variant evidence or evidence of variants? Neurosci Biobehav Rev 28:379-394
117. Helzer JE, Brockington IF, Kendell RE (1981) Predictive validity of DSM-III and Feighner definitions of schizophrenia. A comparison with research diagnosis criteria and CATEGO. Arch Gen Psychiatry 38:791-797
118. Hoche P (1912) Die Bedeutung der Symptomkomplexe in der Psychiatrie. Z Gesamte Neurol Psychiatr 12:540-551
119. Hogarty GE, Ulrich RF, Mussare F, Aristigueta N (1976) Drug discontinuation among long term, successfully maintained schizophrenic outpatients. Dis Nerv Syst 37:494-500
120. Huber G, Gross G, Schuttler R, Linz M (1980) Longitudinal studies of schizophrenic patients. Schizophr Bull 6:592-605
121. Hurlemann R, Matusch A, Kuhn KU, Berning J, Elmenhorst D, Winz O, Kolsch H, Zilles K, Wagner M, Maier W et al (2008) 5-HT(2A) Receptor density is decreased in the at-risk mental state. Psychopharmacology (Berl) 195(4):579-590
122. Iritani S (2007) Neuropathology of schizophrenia: a mini review. Neuropathology 27:604-608
123. Jäger M, Bottlender R, Strauss A, Möller HJ (2004) Fifteen-year follow-up of ICD-10 schizoaffective disorders compared with schizophrenia and affective disorders. Acta Psychiatr Scand 109:30-37
124. Jäger M, Bottlender R, Strauss A, Möller HJ (2004) Klassifikation der funktionellen Psychosen. Die Bedeutung der ICD-10 Diagnosen (Forschungskriterien) für die Vorhersage des Langzeitverlaufes. Fortschr Neurol Psychiat 72:70-78
125. Jäger M, Bottlender R, Strauss A, Möller HJ (2004) The classification of functional psychoses: the impact of ICD-10 diagnoses (research diagnostic criteria) for the prediction of the long-term course. Fortschr Neurol Psychiatr 72:70-78
126. Jäger M, Hintermayr M, Bottlender R, Strauss A, Möller HJ (2003) Course and outcome of first-admitted patients with acute and transient psychotic disorders (ICD-10:F23). Focus on relapses and social adjustment. Eur Arch Psychiatry Clin Neurosci 253:209-215
127. Jakob R, Ustun B, Madden R, Sykes C (2007) The WHO Family of International Classifications. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 50:924-931
128. Jaspers K (1965) Allgemeine Psychopathologie, 8th edn. Springer, Berlin
129. Kahlbaum K (1863) Die Gruppierung der psychischen Krankheiten und die Einteilung der Seelenstörungen. AW Kafemann, Danzig
130. Kanowski S (1982) Clinical and pathological aspects of chronic organic brain syndrome. Exp Brain Res Suppl 5:223-234
131. Kasanin J (1994) The acute schizoaffective psychoses. 1933. Am J Psychiatry 151:144-154
132. Katschnig H, Nutzinger D, Schanda H (1986) Validating depressive subtypes. In: Hippius H, Klerman GL, Matussek N (eds) New results in depression. Springer, Berlin, pp 36-44
133. Katschnig H, Simhandl C (1987) Neuere Ansätze in der Klassifikation und Diagnostik psychischer Krankheiten. In: Simhandl C, Berner P, Luccioni H, Alf C (eds) Moderne psychiatrie. Klassifikationsprobleme in der Psychiatrie. Purkersdorf, Medizinisch-pharmazeutische Verlagsgesellschaft, pp 59-85
134. Katz MM, Cole JO, Barton WE (1966) The role and methodology of classification in psychiatry and psychopathology. Public health service publication no. 1584. National Institute of Mental Health
135. Keck PE Jr, McElroy SL, Havens JR, Altshuler LL, Nolen WA, Frye MA, Suppes T, Denicoff KD, Kupka R, Leverich GS et al (2003) Psychosis in bipolar disorder: phenomenology and impact on morbidity and course of illness. Compr Psychiatry 44:263-269
136. Keefe R (2008) Should cognitive impairment be included in the diagnostic criteria for schizophrenia? World Psychiatry (in press)
137. Kehrer F, Kretschmer E (1924) Die Veranlagung zu seelischen Störungen (Monographien aus dem Gesamtgebiete der neurologie 40). Springer, Berlin
138. Kendell RE (1975) The role of diagnosis in psychiatry. Blackwell, Oxford
139. Kendell RE (1978) The role of diagnosis in psychiatry. Blackwell, Oxford
140. Kendell RE (1981) The importance of diagnosic criteria for biological research. Presentation at the World Congress for Biological Psychiatry, Stockholm
141. Kendell RE (1988) Long-term followup studies: a commentary. Schizophr Bull 14:663-667
142. Kendell RE, Gourlay J (1970) The clinical distinction between the affective psychoses and schizophrenia. Br J Psychiatry 117:261-266
143. Kendler KS (2006) Reflections on the relationship between psychiatric genetics and psychiatric nosology. Am J Psychiatry 163:1138-1146
144. Keri S, Janka Z (2004) Critical evaluation of cognitive dysfunctions as endophenotypes of schizophrenia. Acta Psychiatr Scand 110:83-91
145. Kirkpatrick B, Fenton WS, Carpenter WT, Jr, Marder SR (2006) The NIMH-MATRICS consensus statement on negative symptoms. Schizophr Bull 32:214-219
146. Kleist K (1953) Die Gliederung der neuropsychischen Erkrankungen. Monatsschr Psychiatr Neurol 125:526-554
147. Klosterkotter J, Hellmich M, Steinmeyer EM, Schultze-Lutter F (2001) Diagnosing schizophrenia in the initial prodromal phase. Arch Gen Psychiatry 58:158-164
148. Kraepelin E (1899) Psychiatrie. Ein lehrbuch für Studierende und Ärzte, 6th edn. Johann Ambrosius Barth, Leipzig
149. Kraepelin E (1910) Psychiatire, 8th edn. (1st edn. 1883). Barth, Leipzig
150. Kraepelin E (1919) Dementia Praecox. E.S. Liningstone, Edinburgh
151. Kraepelin E (1920) Die Erscheinungsformen des Irreseins. Z Gesamte Neurol Psychiatr 62:1-29
152. Kreczmanski P, Heinsen H, Mantua V, Woltersdorf F, Masson T, Ulfig N, Schmidt-Kastner R, Korr H, Steinbusch HW, Hof PR et al (2007) Volume, neuron density and total neuron number in five subcortical regions in schizophrenia. Brain 130:678-692
153. Lapierre YD (1994) Schizophrenia and manic-depression: separate illnesses or a continuum? Can J Psychiatry 39:S59-S64
154. Laviolette SR (2007) Dopamine modulation of emotional processing in cortical and subcortical neural circuits: evidence for a final common pathway in schizophrenia? Schizophr Bull 33:971-981
155. Lenzenweger MF, McLachlan G, Rubin DB (2007) Resolving the latent structure of schizophrenia endophenotypes using expectation-maximization-based finite mixture modeling. J Abnorm Psychol 116:16-29
156. Leonhard K (1968) Aufteilung der endogenen Psychosen. Akademie Verlag, Berlin
157. Leonhard K (1968) Aufteilung der endogenen Psychosen. 4th edn. Akademie Verlag, Berlin
158. Lewis CM, Levinson DF, Wise LH, DeLisi LE, Straub RE, Hovatta I, Williams NM, Schwab SG, Pulver AE, Faraone SV et al (2003) Genome scan meta-analysis of schizophrenia and bipolar disorder, part II: Schizophrenia. Am J Hum Genet 73:34-48
159. Lieberman J, Chakos M, Wu H, Alvir J, Hoffman E, Robinson D, Bilder R (2001) Longitudinal study of brain morphology in first episode schizophrenia. Biol Psychiatry 49:487-499
160. Lieberman JA (2006) Neurobiology and the natural history of schizophrenia. J Clin Psychiatry 67:e14
161. Lieberman JA, Tollefson GD, Charles C, Zipursky R, Sharma T, Kahn RS, Keefe RS, Green AI, Gur RE, McEvoy J et al (2005) Antipsychotic drug effects on brain morphology in first-episode psychosis. Arch Gen Psychiatry 62:361-370
162. Lorr M (1966) Explorations in typing psychotics. Pergamon Press, Oxford
163. Lorr M (1974) Assessing psychotic behaviour by the IMPS. In: Pichot P, Olivier-Martin L (eds) Psychological measurements in psychopharmacology. Modern problems in pharmacopsychiatry. Karger, Basel, pp 50-63
164. Lu BY, Martin KE, Edgar JC, Smith AK, Lewis SF, Escamilla MA, Miller GA, Canive JM (2007) Effect of catechol O-methyltransferase val(158) met polymorphism on the p50 gating endophenotype in schizophrenia. Biol Psychiatry 62:822-825
165. Luria RE, Guziec RJ (1981) Comparative description of the SADS and PSE. Schizophr Bull 7:248-257
166. Maier W (2007) Common risk genes for affective and schizophrenic psychoses. Letten Saugstadt Supplement
167. Maier W, Hofgen B, Zobel A, Rietschel M (2005) Genetic models of schizophrenia and bipolar disorder: overlapping inheritance or discrete genotypes? Eur Arch Psychiatry Clin Neurosci 255:159-166
168. Maier W, Zobel A, Rietschel M (2003) Genetics of schizophrenia and affective disorders. Pharmacopsychiatry 36(Suppl 3):S195-S202
169. Maj M (2007) Towards ICD-11 and DSM-V: some current problems of diagnosis in psychiatry. European Psychiatry 22:S1
170. Marneros A (2000) Behandlung schizoaffektiver Psychosen. In: Möller HJ (ed) Therapie psychiatrischer Erkrankungen. Thieme, Stuttgart, pp 484-488
171. Marneros A (2003) Schizoaffective disorder: clinical aspects, differential diagnosis, and treatment. Curr Psychiatry Rep 5:202-205
172. Marneros A (2003) The schizoaffective phenomenon: the state of the art. Acta Psychiatr Scand Suppl 418:29-33
173. Marneros A (2007) Physis does not take leaps, neither does Psyche. World Psychiatry 6:32-33
174. Marneros A (2007) The paradigma of overlapping affective and schizophrenic spectra: schizoaffective conditions. In: Marneros A, Akiskal H (eds) The overlap of affective and schizophrenic spectra. Cambridge University Press, Cambridge, pp 1-24
175. Marneros A, Akiskal H (2007) The overlap of affective and schizophrenic spectra. Cambridge University Press, Cambridge
176. Marneros A, Angst J (2000) Bipolar Disorders. 100 years after manic-depressive insanity. Kluwer, Dordrecht
177. Marneros A, Deister A, Rohde A (1986) The Cologne study on schizoaffective disorders and schizophrenia suspecta. In: Marneros A, Tsuang MT (eds) Schizoaffective psychoses. Springer, Berlin, pp 123-142
178. Marneros A, Deister A, Rohde A (1988) Syndrome shift in the long-term course of schizoaffective disorders. Eur Arch Psychiatry Neurol Sci 238:97-104
179. Marneros A, Deister A, Rohde A (1991) Affektive, schizoaffektive und schizophrene Psychosen. Eine vergleichende langzeitstudie. Springer, Berlin
180. Marneros A, Deister A, Rohde A, Junemann H, Fimmers R (1988) Long-term course of schizoaffective disorders. Part I: definitions, methods, frequency of episodes and cycles. Eur Arch Psychiatry Neurol Sci 237:264-275
181. Marneros A, Roettig S, Roettig D, Tscharntke A, Brieger P (2007) The longitudinal polymorphism of bipolar I disorders and its theoretical implications. J Affect Disord 107(1-3):117-126
182. Marneros A, Röttig S, Röttig D, Tscharntke A, Brieger P (2008) Bipolar I disorder with mood-incongruent psychostic symptoms: A comparative longitudinal study. Eur Arch Psychiatry Clin Neurosci (in press)
183. Martin RL, Cloninger CR, Guze SB, Clayton PJ (1985) Frequency and differential diagnosis of depressive syndromes in schizophrenia. J Clin Psychiatry 46:9-13
184. Maziade M, Roy MA, Chagnon YC, Cliche D, Fournier JP, Montgrain N, Dion C, Lavallee JC, Garneau Y, Gingras N et al (2005) Shared and specific susceptibility loci for schizophrenia and bipolar disorder: a dense genome scan in Eastern Quebec families. Mol Psychiatry 10:486-499
185. McDonald C, Bullmore ET, Sham PC, Chitnis X, Wickham H, Bramon E, Murray RM (2004) Association of genetic risks for schizophrenia and bipolar disorder with specific and generic brain structural endophenotypes. Arch Gen Psychiatry 61:974-984
186. McGlashan TH (1988) A selective review of recent North American long-term studies of schizophrenia. Schizophr Bull 14:11-14
187. Meisenzahl EM, Seifert D, Jäger M, Bottlender R, Schmitt G, Zetzsche T, Koutouleris N, Burgermeister B, Teipel S, Born C et al. (2008) Hippocampal volume reductions in major depression and schizophrenia: a comparative structural MRI study (in press)
188. Meyer AE (1972) Klassifikation von Neurotisch-Kranken (Taxonomien) und von Neurose-Symptomen (Nosologie). In: Kisker KP, Meyer JE, Müller M, Strömgen E (eds) Psychiatrie der Gegenwart. Bd II/1,2, 2nd edn. Springer, Berlin, pp 663-685
189. Meyer-Lindenberg A, Weinberger DR (2006) Intermediate phenotypes and genetic mechanisms of psychiatric disorders. Nat Rev Neurosci 7:818-827
190. Möller HJ (1976) Methodische Grundprobleme der Psychiatrie. Kohlhammer, Stuttgart
191. Möller HJ (1987) Konsequenzen aus der klinischen Psychopharmakologie für die nosologische und syndromatologische Klassifikation funktioneller psychischer Störungen. In: Simhandl Ch, Berner P, Luccioni H, Alf C (eds) Klassifikationsprobleme in der Psychiatrie. Med.-pharmazeutische Verlagsgesellschaft, Pukersdorf, pp 163-188
192. Möller HJ (1995) The negative component in schizophrenia. Acta Psychiatr Scand 91(Suppl 388):11-14
193. Möller HJ (2000) Definition, psychopharmacological basis and clinical evaluation of novel/atypical neuoleptics: methodological issues and clinical consequences. World J Biol Psychiatry 1:75-91
194. Möller HJ (2001) Methodological issues in psychiatry: psychiatry as an empirical science. World J Biol Psychiatry 2:38-47
195. Möller HJ (2004) Course and long-term treatment of schizophrenic psychoses. Pharmacopsychiatry 37(Suppl 2):126-135
196. Möller HJ (2005) Antidepressive effects of traditional and second generation antipsychotics: a review of the clinical data. Eur Arch Psychiatry Clin Neurosci 255:83-93
197. Möller HJ (2005) Occurrence and treatment of depressive comorbidity/cosyndromality in schizophrenic psychoses: conceptual and treatment issues. World J Biol Psychiatry 6:247-263
198. Möller HJ (2005) Problems associated with the classification and diagnosis of psychiatric disorders. World J Biol Psychiatry 6:45-56
199. Möller HJ (2005) Problems associated with the classification and diagnosis of psychiatric disorders. World J Biol Psychiatry 6:45-56
200. Möller HJ (2007) Clinical evaluation of negative symptoms in schizophrenia. Eur Psychiatry 22:380-386
201. Möller HJ (2008) The assessment of cognitive impairment would be a relevant addition to the criteria for diagnosing schizophrenia. World Psychiatry 7(1):35-36
202. Möller HJ, Bottlender R, Groß A, Hoff P, Wittmann J, Wegner U, Strauss A (2002) The Kraepelinian dichotomy: preliminary results of a 15-year follow-up study on functional psychoses: focus on negative symptoms. Schizophr Res 56:87-94
203. Möller HJ, Bottlender R, Jäger M, Strauss A (2008) The Munich 15 years follow up study on first hospitalized patients with schizophrenia and affective psychosis: main outcome results (in preperation)
204. Möller HJ, Bottlender R, Wegner U, Wittmann J, Strauß A (2000) Long-term course of schizophrenic, affective and schizoaffective psychosis: focus on negative symptoms and their impact on global indicators of outcome. Acta Psychiatr Scand 102(Suppl 407):54-57
205. Möller HJ, Hohe-Schramm M, Cording-Tommel C, Schmid-Bode W, Wittchen HU, Zaudig M, von Zerssen D (1989) The classification of functional psychoses and its implications for prognosis. Br J Psychiatry 154:467-472
206. Möller HJ, Hohe-Schramm M, von Zerssen D (1988) Operationalisierte Diagnostik endogener Psychosen nach RDC und DSM-III: Übereinstimmung mit der ICD-Diagnostik und prognostische Bedeutung fÜr den längerfristigen Krankheitsverlauf. In: Beckmann H, Laux G (eds) Biologische Psychiatrie. Synopsis 1986/87. Springer, Berlin, pp 80-85
207. Möller HJ, Piree S, von Zerssen D (1978) Psychiatric classification (author's transl). Nervenarzt 49:445-455
208. Möller HJ, Schid-Bode W, Cording-Tommel C, Wittchen HU, Zerssen D (1988) Psychopathological and social outcome in schizophrenia versus affective/schizoaffective psychoses and prediction of poor outcome in schizophrenia. Results from a 5-8 year follow-up. Acta Psychiatr Scand 77:379-389
209. Möller HJ, Schmid Bode W, Cording-Tömmel C, Wittchen HU, Zaudig M, von Zerssen D (1988) Psychopathological and social outcome in schizophrenia versus affective/schizoaffective psychoses and prediction of poor outcome in schizophrenia. Results from a 5-8 year follow-up. Acta Psychiatr Scand 77:379-389
210. Möller HJ, Schmid Bode W, von Zerssen D (1986) Prediction of long-term outcome in schizophrenia by prognostic scales. Schizophr Bull 12:225-234
211. Möller HJ, von Zerssen D (1980) Probleme und Verbesserungsmö glichkeiten der psychiatrischen Diagnostik. In: Biefang S (ed) Evaluationsforschung in der Psychiatrie. Fragestellungen und Methoden. Enke, Stuttgart, pp 167-207
212. Möller HJ, von Zerssen D (1982) Psychopathometric methods: I. General part. Nervenarzt 53:493-503
213. Möller HJ, von Zerssen D (1983) Psychopathometric procedures: II. Standardized assessment procedures. Nervenarzt 54:1-16
214. Möller HJ, von Zerssen D (1986) Der Verlauf schizophrener Psychosen unter den gegenwärtigen Behandlungsbedingungen. Springer, Berlin
215. Möller HJ, von Zerssen D, Wuschner-Stockheim M, Werner-Eilert K (1981) The prognostic value of psychopathometric data about the psychopathological state of schizophrenic patients on admission and discharge (author's transl). Arch Psychiatr Nervenkr 231:13-34
216. Mombour W (1972) Procedure for standardization of psychopathological findings. 2. Psychiatr Clin (Basel) 5:137-157
217. Mombour W (1974) Syndromes in psychiatric illnesses. A comparative investigation with two rating scales (IMPS and AMP-scale) (author's transl). Arch Psychiatr Nervenkr 219:331-350
218. Mombour W (1975) Klassifikation, Patientenstatistik, Register. In: Kisker KP, Meyer AE, Müller M, Strömgen E (eds) Psychiatrie der Gegenwart. Bd III, 2nd edn. Springer, Berlin, pp 81-118
219. Mombour W (1976) Systematik psychischer Störungen. In: Pongratz LJ (ed) Handbuch der Psychologie, Bd 8, 1st edn. Göttingen, Hogrefe, pp 116-153
220. Mombour W, Gammel G, von Zerssen D, Heyse H (1973) Objectivation of psychiatric syndromes through the multifactorial analysis of the psychopathological status. Nervenarzt 44:352-358
221. Morey LC, Blashfield RK (1981) A symptom analysis of the DSM-III definition of schizophrenia. Schizophr Bull 7:258-268
222. Mulert C, Jager L, Pogarell O, Bussfeld P, Schmitt R, Juckel G, Hegerl U (2002) Simultaneous ERP and event-related fMRI: focus on the time course of brain activity in target detection. Methods Find Exp Clin Pharmacol 24(Suppl D):17-20
223. Müller N, Schwarz MJ (2007) The immunological basis of glutamatergic disturbance in schizophrenia: towards an integrated view. J Neural Transm Suppl 72:269-280
224. Murray RM, Dutta R (2007) The right answer for the wrong reasons? World Psychiatry 6:29-30
225. Murray RM, Sham P, van Os J, Zanelli J, Cannon M, McDonald C (2004) A developmental model for similarities and dissimilarities between schizophrenia and bipolar disorder. Schizophr Res 71:405-416
226. Neumeister A, Young T, Stastny J (2004) Implications of genetic research on the role of the serotonin in depression: emphasis on the serotonin type 1A receptor and the serotonin transporter. Psychopharmacol (Berl) 174:512-524
227. Overall HE, Klett CJ (1972) Applied multivaried analysis. McGraw-Hill, New York
228. Parker G (2000) Classifying depression: should paradigms lost be regained? Am J Psychiatry 157:1195-1203
229. Parker G (2002) Differential effectiveness of newer and older antidepressants appears mediated by an age effect on the phenotypic expression of depression. Acta Psychiatr Scand 106:168-170
230. Parker G, Roy K, Wilhelm K, Mitchell P (2001) Assessing the comparative effectiveness of antidepressant therapies: a prospective clinical practice study. J Clin Psychiatry 62:117-125
231. Paykel ES (1977) Response to treatmetn and depressive classification. In: Burrows GD (ed) Handbook of studies on depression. Excerpta Media, Amsterdam, pp 21-47
232. Phillip M, Maier W, Benkert O (1986) Dimensional classification as an instrument for biological research in endogenous depression. In: Hippius H, Klerman GL, Matussek N (eds) New results in depression. Springer, Berlin, pp 145-155
233. Phillip M, Maier W, Wilhelmi D (1986) Das polydiagnostische Interview (PODI). Psycho 12:394-395
234. Pietzcker A, Gebhardt R, Freudenthal K, Langer C (1981) The potential of psychopathological symptoms to differentiate diagnostic groups (author's transl). Arch Psychiatr Nervenkr 230:141-157
235. Pietzcker A, Gebhardt R, Strauss A, Stockel M, Langer C, Freudenthal K (1983) The syndrome scales in the AMDP-System. Mod Probl Pharmacopsychiatry 20:88-99
236. Pincus HA, Tew JD, First MB (2004) Psychiatric comorbidity: Is more less? World Psychiatry 3:18-23
237. Rapoport JL, Addington AM, Frangou S, Psych MR (2005) The neurodevelopmental model of schizophrenia: update 2005. Mol Psychiatry 10:434-449
238. Regier DA, Sirovatka P, Rubio-Stipec M, Narrow WE (2007) The future of psychiatric diagnosis: thr APA/WHO/NIH research planning for DSM and ICD. Die Psychiatrie 2:98-104
239. Reichenberg A, Weiser M, Rabinowitz J, Caspi A, Schmeidler J, Mark M, Kaplan Z, Davidson M (2002) A population-based cohort study of premorbid intellectual, language, and behavioral functioning in patients with schizophrenia, schizoaffective disorder, and nonpsychotic bipolar disorder. Am J Psychiatry 159:2027-2035
240. Rennert H (1977) Etiology and classification of mental disorders from viewpoint of "Universal genesis of psychoses". Psychiatr Neurol Med Psychol (Leipz) 29:9-13
241. Roth M, Garside R, Gurney C (1974) Classification of depressive disorders. In: Angst J (ed) Classification and prediction of outcome of depression. Schattauer, Stuttgart, pp 3-26
242. Ruhrmann S, Schultze-Lutter F, Klosterkotter J (2003) Early detection and intervention in the initial prodromal phase of schizophrenia. Pharmacopsychiatry 36(Suppl 3):S162-S167
243. Rujescu D, Bender A, Keck M, Hartmann AM, Ohl F, Raeder H, Giegling I, Genius J, McCarley RW, Moller HJ et al (2006) A pharmacological model for psychosis based on N-methyl-d-aspartate receptor hypofunction: molecular, cellular, functional and behavioral abnormalities. Biol Psychiatry 59:721-729
244. Rujescu D, Hartmann AM, Gonnermann C, Moller HJ, Giegling I (2003) M129V variation in the prion protein may influence cognitive performance. Mol Psychiatry 8:937-941
245. Rujescu D, Meisenzahl EM, Giegling I, Kirner A, Leinsinger G, Hegerl U, Hahn K, Moller HJ (2002) Methionine homozygosity at codon 129 in the prion protein is associated with white matter reduction and enlargement of CSF compartments in healthy volunteers and schizophrenic patients. Neuroimage 15:200-206
246. Rujescu D, Meisenzahl EM, Krejcova S, Giegling I, Zetzsche T, Reiser M, Born CM, Moller HJ, Veske A, Gal A et al (2007) Plexin B3 is genetically associated with verbal performance and white matter volume in human brain. Mol Psychiatry 12:190-194, 115
247. Saugstad LF (1994) The maturational theory of brain development and cerebral excitability in the multifactorially inherited manic-depressive psychosis and schizophrenia. Int J Psychophysiol 18:189-203
248. Saugstad LF (1999) A lack of cerebral lateralization in schizophrenia is within the normal variation in brain maturation but indicates late, slow maturation. Schizophr Res 19, 39:183-196
249. Saugstad LF (2001) Manic depressive psychosis and schizophrenia are neurological disorders at the extremes of CNS maturation and nutritional disorders associated with a deficit in marine fat. Med Hypotheses 57:679-692
250. Saugstad LF (2008) Kraepelin's dichotomy is true: contrasting brain dysfunction at the extremes, excitability, a fundamental property of nervous tissue, is affected. World J Biol Psychiatry (in press)
251. Saugstad LF (2007) What are Psychosis and where is it located in this supplement. Eur Arch Psychiatry Clin Neurosci 258 [Suppl 2]:111-117
252. Schmitt GJ, Meisenzahl EM, Dresel S, Tatsch K, Rossmuller B, Frodl T, Preuss UW, Hahn K, Moller HJ (2002) Striatal dopamine D2 receptor binding of risperidone in schizophrenic patients as assessed by 123I-iodobenzamide SPECT: a comparative study with olanzapine. J Psychopharmacol 16:200-206
253. Schonell H (1988) Efficiency of the AMDP anamnestic data in psychiatric research. Pharmacopsychiatry 21:456-457
254. Schou M (1980) Lithium-Behandlung der manisch-depressiven Krankheit. Thieme, Stuttgart
255. Schulze TG, Ohlraun S, Czerski PM, Schumacher J, Kassem L, Deschner M, Gross M, Tullius M, Heidmann V, Kovalenko S et al (2005) Genotype-phenotype studies in bipolar disorder showing association between the DAOA/G30 locus and persecutory delusions: a first step toward a molecular genetic classification of psychiatric phenotypes. Am J Psychiatry 162:2101-2108
256. Schulze TG, Ohlraun S, Czerski PM, Schumacher J, Kassem L, Deschner M, Gross M, Tullius M, Heidmann V, Kovalenko S et al (2005) Genotype-phenotype studies in bipolar disorder showing association between the DAOA/G30 locus and persecutory delusions: a first step toward a molecular genetic classification of psychiatric phenotypes. Am J Psychiatry 162:2101-2108
257. Schumacher J, Cichon S, Rietschel M, Nothen MM, Propping P (2002) Genetics of bipolar affective disorders. Current status of research for identification of susceptibility genes. Nervenarzt 73:581-592
258. Segurado R, Detera-Wadleigh SD, Levinson DF, Lewis CM, Gill M, Nurnberger JI Jr, Craddock N, DePaulo JR, Baron M, Gershon ES et al (2003) Genome scan meta-analysis of schizophrenia and bipolar disorder, part III: bipolar disorder. Am J Hum Genet 73:49-62
259. Spitzer RL, Endicott J, Robins E (1975) Prliminary report of the reliability of Research Diagnostic Criteria applied to psychiatric case reports. In: Sudilovsky A, Gershon S, Beer B (eds) Predictability in psychopharmacology and clinical correlations. Raven Press, New York, pp 1-47
260. Spitzer RL, Endicott J, Robins E (1978) Research diagnostic criteria: rationale and reliability. Arch Gen Psychiatry 35:773-782
261. Spitzer RL, Forman JB, Nee J (1979) DSM-III field trials: I. Initial interrater diagnostic reliability. Am J Psychiatry 136:815-817
262. Strakowski SM, Williams JR, Sax KW, Fleck DE, DelBello MP, Bourne ML (2000) Is impaired outcome following a first manic episode due to mood-incongruent psychosis? J Affect Disord 61:87-94
263. Strauss JS, Carpenter WT Jr, Bartko JJ (1974) The diagnosis and understanding of schizophrenia, Part III. Speculations on the processes that underlie schizophrenic symptoms and signs. Schizophr Bull 11:61-69
264. Subotnik KL, Nuechterlein KH, Asarnow RF, Fogelson DL, Goldstein MJ, Talovic SA (1997) Depressive symptoms in the early course of schizophrenia: relationship to familial psychiatric illness. Am J Psychiatry 154:1551-1556
265. Tamminga CA (2006) The neurobiology of cognition in schizophrenia. J Clin Psychiatry 67:e11
266. Thaker GK (2007) Schizophrenia endophenotypes as treatment targets. Expert Opin Ther Targets 11:1189-1206
267. Tsuang MT, Dempsey GM (1979) Long-term outcome of major psychoses. II. Schizoaffective disorder compared with schizophrenia, affective disorders, and a surgical control group. Arch Gen Psychiatry 36:1302-1304
268. van Os J, Fahy TA, Jones P, Harvey I, Sham P, Lewis S, Bebbington P, Toone B, Williams M, Murray R (1996) Psychopathological syndromes in the functional psychoses: associations with course and outcome. Psychol Med 26:161-176
269. van Os J, Gilvarry C, Bale R, Van Horn E, Tattan T, White I, Murray R (1999) A comparison of the utility of dimensional and categorical representations of psychosis. UK700 Group. Psychol Med 29:595-606
270. Van Praag HM, Asnis GM, Kahn RS, Brown SL, Korn M, Friedman JM, Wetzler S (1990) Nosological tunnel vision in biological psychiatry. A plea for a functional psychopathology. Ann N Y Acad Sci 600:501-510
271. van Rd V (1993) Reactualization of the concept of unitary psychosis introduced by Joseph Guislain. Acta Psychiatr Belg 93:203-219
272. Volz HP, Möller HJ (1994) Antidepressant drug therapy in the elderly-a critical review of the controlled clinical trials conducted since 1980. Pharmacopsychiatry 27:93-100
273. von Zerssen D, Pfister H, Koeller DM (1988) The Munich personality test (MPT)-a short questionnaire for self-rating and relatives' rating of personality traits: formal properties and clinical potential. Eur Arch Psychiatry Neurol Sci 238:73-93
274. Watt DC, Katz K, Shepherd M (1983) The natural history of schizophrenia: a 5-year prospective follow-up of a representative sample of schizophrenics by means of a standardized clinical and social assessment. Psychol Med 13:663-670
275. Weinberger DR, Wagner RL, Wyatt RJ (1983) Neuropathological studies of schizophrenia: a selective review. Schizophr Bull 9:193-212
276. Weis S, Llenos IC, Dulay JR, Elashoff M, Martinez-Murillo F, Miller CL (2007) Quality control for microarray analysis of human brain samples: the impact of postmortem factors, RNA characteristics, and histopathology. J Neurosci Methods 165:198-209
277. Williams GV, Castner SA (2006) Under the curve: critical issues for elucidating D1 receptor function in working memory. Neuroscience 139:263-276
278. Williams NA, Close JP, Giouzeli M, Crow TJ (2006) Accelerated evolution of protocadherin11X/Y: a candidate gene-pair for cerebral asymmetry and language. Am J Med Genet B Neuropsychiatr Genet 141:623-633
279. Williams NM, Green EK, Macgregor S, Dwyer S, Norton N, Williams H, Raybould R, Grozeva D, Hamshere M, Zammit S et al (2006) Variation at the DAOA/G30 locus influences susceptibility to major mood episodes but not psychosis in schizophrenia and bipolar disorder. Arch Gen Psychiatry 63:366-373
280. Wing JK, Cooper JE, Sartorius N (1974) Measurement and classification of psychiatric symptoms. Camebridge University Press, Camebridge
281. Wittchen HU, Semler G (1991) Composite international diagnostic interview (CIDI, Version 1.0). Beltz, Weinheim
282. Wittchen HU, Zaudig M, Spengler P, Mombour W, Hiller W, Essau CA, Rummler R, Spitzer RL, Williams J (1991) Wie zuverlässig ist operationalisierte Diagnostik? Die Test-Retest Reliabilität des Strukturierten Interviews für DSM-III-R. Z Klin Psychol 20:136-153
283. Wittenborn JR (1977) Stability of symptom ratings for schizophrenic men. Arch Gen Psychiatry 34:437-440
284. Wittorf A, Wiedemann G, Buchkremer G, Klingberg S (2008) Prediction of community outcome in schizophrenia one year after discharge from inpatient treatment. Eur Arch Psychiatry Clin Neurosci 258(1):48-58
285. Wittorf A, Wiedemann G, Buchkremer G, Klingberg S (2007) Prediction of community outcome in schizophrenia one year after discharge from inpatint treatment. Eur Arch Psychiatry Clin Neurosci 258(1):48-58
286. Woodward ND, Purdon SE, Meltzer HY, Zald DH (2005) A meta-analysis of neuropsychological change to clozapine, olanzapine, quetiapine, and risperidone in schizophrenia. Int J Neuropsychopharmacol 8:457-472
287. World Health Organization (WHO) (1973) The international pilot study of schizophrenia. WHO, Geneva
288. World Health Organization (WHO) (1991) Schedule for the clinical assessment in neuropsychiatry. WHO, Geneva
289. World Health Organization (WHO) (1992) International classification of mantal disorders. ICD-10, Chapt V (F). Clinical descriptions and diagnostic guidelines. WHO, Geneva
290. World Health Organization (WHO) (1992) International Statistical Classification of Diseases and Related Health Problems, 1oth revision. WHO, Geneva
291. World Health Organization (WHO) (1993) International classification of mantal disorders. ICD-10, Chapt V (F). Diagnostic criteria for research (DCR). WHO, Geneva
292. Zeller E (1837) Bericht über die Wirksamkeit der heilanstalt Winnenthal von ihrer Eröffnung den 1. März 1834 bis zum 28. Februar 1837. Beil med Corresp Bl Wurtemb ärztl Ver 7:321-335
293. Zerssen Dv (1973) Methoden der Konstitutions- und Typenforschung. In: Thiel M (ed) Enzyklopädie der geisteswissenschaftlichen Arbeitsmethoden, 9. Lieferung: Methoden der Anthropologie, Anthropologie, Völkerkunde und Religionswissenschaft. München, Wien, Oldenbourg, pp 35-143
294. Zerssen Dv (1973) Nosologie. In: Müller C (ed) Lexikon der Psychiatrie. Springer, Berlin, pp 355-357
295. Zerssen Dv (1973) Syndrom. In: Müller C (ed) Lexikon der Psychiatrie. Springer, Berlin, pp 508-509
296. Zerssen Dv (1973) Typus. In: Müller C (ed) Lexikon der Psychiatrie. Springer, Berlin, pp 540-542