Synthesis and biological evaluation of 14-alkoxymorphinans. Part 19: Effect of 14-O-benzylation on the opioid receptor affinity and antagonist potency of naltrexone

Helvetica Chimica Acta

Volumn 86, Issue 7, 2003, Pages 2335-2341

  Schüllner, Falko ^a   Meditz, Ruth ^a   Krassnig, Roland ^a   Morandell, Günther ^a   Kalinin, Valery N ^b   Sandler, Ellen ^a   Spetea, Mariana ^a   White, Angela ^c   Schmidhammer, Helmut ^a   Berzetei Gurske, Ilona P ^c  

^a UNIVERSITY OF INNSBRUCK   (Austria)

^b A N NESMEYANOV INSTITUTE OF ORGANOELEMENT COMPOUNDS   (Russian Federation)

^c SRI INTERNATIONAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; BIOASSAY; BIOCHEMISTRY;

LIGANDS;

AROMATIC COMPOUNDS;

14 O BENZYLNALTREXONE; 14BETA (BENZYLOXY) 17 (CYCLOPROPYLMETHYL) 4,5ALPHA EPOXY 3 HYDROXYMORPHINAN 6 ONE; GUANOSINE TRIPHOSPHATE; MORPHINAN DERIVATIVE; NALTREXONE DERIVATIVE; OPIATE RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; DRUG ACTIVITY; DRUG DETERMINATION; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; PRIORITY JOURNAL;

EID: 4244140123     PISSN: 0018019X     EISSN: None     Source Type: Journal    
DOI: 10.1002/hlca.200390187     Document Type: Article

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