Gastric cytoprotection and adaptation to ethanol

Alcohol and the Gastrointestinal Tract

Volumn , Issue , 2017, Pages 123-141

  Konturek, Stanisław J ^a   Stachura, Jerzy ^a   Konturek, Jan W ^a  

^a JAGIELLONIAN UNIVERSITY MEDICAL COLLEGE   (Poland)

Author keywords

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Indexed keywords

EID: 4243813284     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.4324/9781315149844     Document Type: Chapter

References (72)

1. Oates, P. J., Gastric blood flow and mucosal defense, in Gastric Cytoprotection. A Clinicians Guide. Hollander, D. and Tarnawski. A. S., Eds. Plenum Medical Book Company, New York. 1989. chap. 7.
2. Tepperman, B. L. and Jacobson, E. D., Circulatory factors in gastric mucosal defense and repair, in Physiology of the Gastrointestinal Tract. Johnson. L. R. Ed., Raven Press, New York, 1994, 1331.
3. Robert, A., Nezamis, J. T., Davies, J. P., Field, S. A., and Hanchar, A. J., Mild irritant prevent gastric necrosis through “adaptive cytoproiection" mediated by prostaglandins. Ant. J. Physiol., 245, G113, 1983.
4. Konturek, S. J., Brzozowski, T., Piastucki, I., Radecki, T., and Dembinska-Kiec, A., Role of locally generated prostaglandins in adaptive gastric cytoprotection. Dig. Dis. Sci., 27, 967, 1982.
5. Tepperman, B. L., Soper, B. D., and Morris, G. P., Effect of sialoadenectomy on adaptive cytoprotection in the rat, Gastroenterology, 97, 123, 1989.
6. Konturek, S. J., Brzozowski, T., Majka, J., Szlachcic, A., and Czarnobilski, K., Nitric oxide in gastroprotection by sucralfate, mild irritant and nocloprost. Role of mucosal blood flow, Dig. Dis. Sci., 39, 593, 1994.
7. Matsumoto, J., Veshima, K., Takeuchi, K., and Okabe, S., Capsaicin-sensitive afferent neurons in adaptive responses of the rat stomach induced by a mild irritant, Jpn. J. Pharmacol., 55. 181, 1991.
8. Konturek, S. J. and Konturek, J. W., Gastric adaptation. Basic and clinical aspects, Digestion, 55, 131, 1994.
9. Tarnawski, A., Lu, S. Y., Stachura, J., and Sarfeh, I. J., Adaptation of gastric mucosa to chronic alcohol administration is associated with increased mucosal expression of growth factors and their receptors, Scand. J. Gastroenterol., 193 (Suppl.), 59, 1992.
10. Chari, S., Teyssen, S., and Singer, M. U., Alcohol and gastric acid secretion in humans, Gut, 34, 843, 1993.
11. Konturek, S. J., Mach, T., Konturek, J. W., Bogdal, J., and Stachura, J., Comparison of sucralfate and ranitidine in gastroprotection against alcohol in humans, Am. J. Med., 86, 55, 1989.
12. Pares, X., Cederlung, E., Moreno, A., Helmquist, L., Farres, J., and Jornvall, H., Mammalian class IV alcohol dehydrogenase (stomach alcohol dehydrogenase); structure, origin and correlation with enzymology, Proc. Natl. Acad. Sci. U.S.A., 91, 1893, 1994.
13. Seitz, H. K., Egerer, G., Simanowski, V. A., Waldherr, R., Eckey, R., Agarwal, D. P., Gredde, H. W., and Warthburg, J. P., Human gastric alcoholic dehydrogenase activity: effect of age, sex and alcoholism, Gut, 34, 1433, 1933.
14. Lim, R. T., Gentry, R. T., Ito, D., Tokoyama, H., Baraona, E., and Lieber, G. S., First-pass metabolism of ethanol is predominantly gastric. Alcoholism: Clin. Exp. Res., 17, 1337, 1993.
15. Goldstein, D. B., Pharmacology of Alcohol, Oxford University Press, New York, 1983, 3.
16. Stachura, J., Pathomorphology of gastric mucosal injury, in Gastric Cytoprotection. A Clinicians Guide, Hollander. D. and Tarnawski, A., Eds., Plenum Press, New York, 1989, 33.
17. Solcia, E., Capella, C., Buffa, R., Usellini, L., Fiocca, R., and Sessa, T., Endocrine cells in the digestive system, in Physiology of the Gastrointestinal Tract, Johnson, L. R., Ed„ Raven Press, New York, 1987, 111.
18. Stachura, J., Tarnawski, A., and Dabros, W., Apoptosis: genetically programmed physiologic cell loss in normal gastric oxyntic mucosa and in mucosa of grossly healed gastric ulcer, J. Clin. Gastroenterol., 17, S70, 1993.
19. Johnson, L. R. and McCormack, S. A., Regulation of gastrointestinal mucosal growth, in Physiology of the Gastrointestinal Tract, Johnson, L. R. Ed. Raven Press, New York, 1994, 611.
20. Piasecki, C., Evidence for an infarctive pathogenesis of acute and chronic gastroduodenal ulceration, J. Physiol. Pharmacol., 43, 99, 1992.
21. Ito, S. and Lacy, E. R., Morphology of rat gastric mucosal damage. Defense and restitution in the presence of luminal ethanol. Gastroenterology, 88, 250. 1985.
22. Lacy, E. R., Gastric mucosal resistance to a repeated ethanol insult, Scand. J. Gastroenterol., 20 (Suppl. 1). 63, 1985.
23. Tarnawski, A., Stachura, J., Hollander, D., Sarfeh, I. J., and Bogdal, J., Cellular aspects of alcohol-induced injury of the human gastric mucosa. Focus on the mucosal microvessels, J. Clin. Gastroenterol, 10 (Suppl. I). 553, 1988.
24. Tarnawski, A., Stachura, J., Gergely, H., and Hollander, D., Microvascular endothelium — a major target for alcohol injury of the human gastric mucosa. Histochemical and ultrastructural study, J. din. Gastroenterol., 10 (Suppl. 1), 553, 1988.
25. Robert, A., Cytoprotection by prostaglandins, Gastroenterology, 77, 761, 1979.
26. Robert, A., Nezamis, J. E., Lancaster, C., and Hanchar, A. J., Cytoprotection by prostaglandins in rats. Prevention of gastric necrosis produced by alcohol, HC1, NaOH, hypertonic NaCl and thermal injury, Gastroenterology, 77, 433, 1979.
27. Lacy, E. R. and Ito, S., Microscopic analysis of ethanol damage to rat gastric mucosa after treatment with prostaglandin. Gastroenterology, 83, 619. 1982.
28. Lacy, E. R. and Ito, S., Rapid epithelial restitution of the rat gastric mucosa after ethanol injury, Lab. Invest., 51. 573, 1984.
29. Ito, S., Lacy, E. R., Rutten, M. J., Critchlow, J., and Silen, W., Rapid repair of injured gastric mucosa, Scand. J. Gastroenterol., 19 (Suppl. 101), 87, 1984.
30. Konturek, S. J., Mechanisms of gastroprotection, Scand. J. Gastroenterol., 25 (Suppl. 174), 15, 1990.
31. Konturek, S. J., Brzozowski, T., Drozdowicz, D., and Pytko, J., Gastroprotection by cholecystokinin (CCK) against ethanol damage. Role of CCK-A and CCK-B receptors and nitric oxide (NO), Gastroenterology, 106, 4, A110, 1994.
32. Tarnawski, A., Hollander, D., Stachura, J., Krause, W. J., and Gergely, H., Prostaglandin protection of the gastric mucosa against alcohol injury — a dynamic tile-related process. Role of muscular proliferative zone. Gastroenterology, 88, 334. 1985.
33. Wallace, J. L. and Whittle, B. J., Role of mucus in the repair of gastric epithelial damage in the rat. Inhibition of epithelial recovery by mucolytic agents, Gastroenterology, 91. 603, 1986.
34. Paimela, H., Goddard, P. J., Carter, K., Khakee, R., McNeil, P. L., Ito, S., and Silen, W., Restitution of frog gastric mucosa in vitro: effect of basic fibroblast growth factor. Gastroenterology, 104, 1337, 1993.
35. 2, Br. J. Pharmacol., 86, 838, 1985.
36. Guth, P. H., Paulsen, G., and Nagata, H., Histological and microcirculatory changes in alcohol-induced gastric lesions in rats: effect of prostaglandin cytoprotection, Gastroenterology, 87. 1083, 1984.
37. Leung, F. W., Robert, A., and Guth, P. H., Gastric mucosal blood flow in rats after administration of 16,16-dimethyl prostaglandin Ei at a cytoprotective dose, Gastroenterology, 88, 1948. 1985.
38. Rowe, P. H., Starlinger, M. J., Kasdon, E., Marrone, G., and Silen, W., Effect of simulated systemic administration of aspirin, salicylate and indomethacin on amphibian gastric mucosa, Gastroenterology, 90, 559, 1986.
39. Tarnawski, A., Brzozowski, T., Sarfeh, I. J., Krause, W. J., Ulich, T. R., Gergely, H., and Hollander, D., Prostaglandin protection of human isolated gastric glands. Evidence for direct cellular action of prostaglandin. J. Clin. Invest., 81, 1091, 1988.
40. Kvietys, P. R., Twohig, B., Danzell, J., and Specian, D. N., Ethanol-induced injury to the rat gastric mucosa. Role of neutrophils and xantine oxidase-derived radicals, Gastroenterology, 98, 909. 1990.
41. Wallace, J. E., Arfors, K.-E., and McNight, G. W., A monoclonal antibody against the CD 18 leukocyte adhesion molecule prevents indomethacin-induced gastric damage in the rabbit. Gastroenterology, 100, 878, 1991.
42. Wallace, J. L., Increased resistance of the rat gastric mucosa to hemorrhagic damage after exposure to an irritant. Role of “mucoid cap” and prostaglandin synthesis, Gastroenterology, 94, 22, 1988.
43. Hawkey, C. J., Kemp, R. T., Walt, R. P., Bhaskar, N. K., Davies, J., and Filipowicz, B., Evidence that adaptive cytoprotection in rats is not mediated by prostaglandins, Gastroenterology, 94. 948, 1988.
44. 2 and thiosulfate increase gastric mucosal penetration of hypertonic NaCI and increase net transmucosal water flux. Gastroenterology, 94, A354, 1988.
45. Tarnawski, A., Hollander, D., Stachura, J., and Krause, W., Arachidonic acid protection of gastric mucosa against alcohol injury: sequential analysis of morphologic and functional changes, J. Lab. Clin. Med., 102, 340, 1983.
46. Svanes, K., Gislason, H., Guttu, K., Herfjord, J. K., Fevang, J., and Gronbech, J. E., Role of blood flow in adaptive protection of the cat gastric mucosa, Gastroenterology, 100, 1249, 1991.
47. Endo, K., Kao, J., Bomek, M. J., and Leung, F. W., Mechanism of gastric hyperemia induced by intragastric hypertonic saline in rats, Gastroenterology, 104. 114, 1993.
48. Konturek, S. J., Brzozowski, T., Majka, J., Szlachcic, A., Nauert, Ch., and Słomiany, B., Nitric oxide in gastroprotection by aluminum-containing antacids, Eitr. J. Pharmacol., 229, 155, 1992.
49. Whittle, B. J. R., Lopez-Belmonte, J., and Moncada, S., Regulation of gastric mucosal integrity by endogenous nitric oxide; interactions with prostanoids and sensory neuropeptides in the rat. Br. J. Pharmacol., 99, 607. 1990.
50. Whittle, B. J. R., Nitric oxide in gastrointestinal physiology and pathology, in Physiology of the Gastrointestinal Tract, Johnson, L. R. Ed., Raven Press, New York, 1994, 267.
51. Brzozowski, T., Drozdowicz, D., Szlachcic, A., Pytko-Polonczyk, J., Majka, J., and Konturek, S. J., Role of nitric oxide and prostaglandins in gastroprotection induced by capsaicin and papaverine, Digestion, 54, 24, 1993.
52. Konturek, S. J., Radecki, T., Piastucki, I., Brzozowski, T., and Drozdowicz, D., Gastroprotection by colloidal bismuth subcitrate (De-Nol) and sucralfate. Role of endogenous prostaglandins, Gut, 28. 201, 1987.
53. Konturek, S. J., Brzozowski, T., Marks, N. J., Miederer, S., Peskar, B. M., Preclik, G., and Weberg, R., Antacids and mucosal protection. Eur. J. Gastroenterol. Hepatol., 4, 954. 1992.
54. Konturek, S. J., Piastucki, I., Brzozowski, T., Dembinska-Kiec, A., and Gryglewski, R., Role of prostaglandins in the formation of apirin-induced gastric ulcers, Gastroenterology, 80, 4. 1981.
55. Rainford, K. D. and Willis, C., Relationship of gastric mucosal damage induced in pigs by antiinflammatory drugs to their effect on prostaglandin production. Dig. Dis. Sci., 27, 624, 1992.
56. Wallace, J. L., Non-steroidal anti-inflammatory drug gastropathy and cytoprotection. Pathogenesis and mechanisms re-examined. Stand. J. Gastroenterol., 27 (Suppl. 192), 3, 1992.
57. St. John, D. J. B., Yeomans, N. D., McDermott, F. T., and de Boer, W. G. R. M., Adaptation of the gastric mucosal to repeated administration of aspirin in the rat, Am. J. Dig. Dis., 18, 881, 1973.
58. Graham, D. Y., Smith, J. L., and Dobbs, S. M., Gastric adaptation occurs with aspirin administration in man. Am. J. Dig. Dis., 28, I, 1983.
59. Robert, A., Lancaster, C., Olafsson, A. S., Gilberston-Beadling, S., and Zhang, W., Gastric adaptation to the ulcerogenic effect of aspirin. Gastroenterology, 1, 73, 1991.
60. Konturek, S. J., Brzozowski, T., Konturek, J. W., and Domschke, W., Role of prostaglandins, sensory nerves, nitric oxide and growth factors in gastric adaptation to topical irritants, J. Physiol. Pharmacol., 44 (Suppl. 2), 69, 1993.
61. Wright, N. A., Pike, C., and Elia, G., Induction of an epithelial growth factor-secreting lineage by mucosal ulceration in human gastrointestinal stem cells, Nature, 343, 82, 1990.
62. Polk, W. H., Dempsey, P. J., Russel, W. E., Brown, P. I., Beauchamp, R. D., Bernard, J. A., and Coffey, R. J., Increased production of transforming growth factor alpha following acute gastric injury, Gastroenterology, 102, 1467, 1992.
63. Robert, A., Lancaster, C., Olafson, A. S., and Zhang, W., Gastric adaptation of repeated administrations of a necrotizing agent, in Mechanisms of Injury Protection and Repair of the Upper Gastrointestinal Tract, Garner. A. and O'Brien. P. G. Eds., Chichester, Wiley, 1991, 357.
64. Lacy, E. K., Cowart, K. S., and Hund, P., Effects of chronic superficial injury on the rat gastric mucosa. Gastroenterology, 103, 1179, 1992.
65. Ivey, K. J., Tarnawski, A., and Stachura, J., The induction of gastric mucosal tolerance to alcohol by chronic administration, J. Lab. Clin. Med., 96. 922, 1980.
66. Goldstein, D. B., Ethanol-induced adaptation in biological membranes, Ann. N.Y. Acad. Sci., 492. 103, 1987.
67. Brzozowski, T., Drozdowicz, D., Stachura, J., and Konturek, S. J., Gastric mucosa adapted to aspirin (ASA) or stress is more resistant to the damage induced by strong irritants, Gastroenterology, 106, A58, 1994.
68. Morson, B. C. and Dawson, I. M. P., Gastrointestinal Pathology, Blackwell Science Publishers, Oxford. 1990. 94.
69. Whitehead, R., Mucosal Biopsy of the Gastrointestinal Tract, W. B. Saunders, Philadelphia, 1990, 84.
70. Dinoso, V. P., Jr., Chey, W. Y., and Braverman, S. P., Gastric secretion and gastric mucosal morphology in chronic alcoholics. Arch. Intern. Med., 130. 715. 1972.
71. Brown, R. C., Hardy, G. J., and Temperly, J. M., Gastritis and cirrhosis: no association, J. Clin. Pathol34. 744. 1981.
72. Quinn, C. M., Bjarnason, I., and Price, A. B., Gastritis in patients on non-steroidal anti-inflammatory drugs. Histopathology, 23, 341, 1993.