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Volumn 6, Issue 2, 1996, Pages 45-53

Resistance to activated protein C due to a factor V gene mutation: The most common inherited risk factor of thrombosis

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD CLOTTING FACTOR 5; PROTEIN C; PROTEIN S;

EID: 4243738904     PISSN: 10501738     EISSN: None     Source Type: Journal    
DOI: 10.1016/1050-1738(95)00130-1     Document Type: Short Survey
Times cited : (22)

References (89)
  • 1
    • 84921237177 scopus 로고
    • Molecular mechanisms of activated protein C resistance based on studies using purified FV: Q506
    • in press
    • Aparicio C, Dahlbäck B: 1995. Molecular mechanisms of activated protein C resistance based on studies using purified FV: Q506. Biochemistry J (in press).
    • (1995) Biochemistry J
    • Aparicio, C.1    Dahlbäck, B.2
  • 3
    • 0029080220 scopus 로고
    • Management of patients with hereditary defects predisposing to thrombosis including pregnant women
    • Bauer KA: 1995. Management of patients with hereditary defects predisposing to thrombosis including pregnant women. Thromb Haemost 74:94-100.
    • (1995) Thromb Haemost , vol.74 , pp. 94-100
    • Bauer, K.A.1
  • 5
    • 0028314865 scopus 로고
    • Mutation in blood coagulation factor V associated with resistance to activated protein C
    • Bertina RM, Koeleman BPC, Koster T, et al.: 1994. Mutation in blood coagulation factor V associated with resistance to activated protein C. Nature 369:64-67.
    • (1994) Nature , vol.369 , pp. 64-67
    • Bertina, R.M.1    Koeleman, B.P.C.2    Koster, T.3
  • 6
    • 0029080341 scopus 로고
    • Resistance to activated protein C and factor V Leiden as risk factors for venous thrombosis
    • Bertina RM, Reitsma PH, Rosendaal FR, Vandenbroucke JP: 1995. Resistance to activated protein C and factor V Leiden as risk factors for venous thrombosis. Thromb Haemost 74:449-453.
    • (1995) Thromb Haemost , vol.74 , pp. 449-453
    • Bertina, R.M.1    Reitsma, P.H.2    Rosendaal, F.R.3    Vandenbroucke, J.P.4
  • 7
    • 0024507770 scopus 로고
    • The clinical spectrum of heterozygous protein C deficiency in a large New England kindred
    • Bovill EG, Bauer KA, Dickermann JD, Callas P, West B: 1989. The clinical spectrum of heterozygous protein C deficiency in a large New England kindred. Blood 73:712-717.
    • (1989) Blood , vol.73 , pp. 712-717
    • Bovill, E.G.1    Bauer, K.A.2    Dickermann, J.D.3    Callas, P.4    West, B.5
  • 8
    • 0000581205 scopus 로고
    • Hereditary protein C deficiency
    • Bertina RM, ed. Edinburgh, Churchill Livingstone
    • Broekmans AW, Conard J: 1988. Hereditary protein C deficiency. In Bertina RM, ed. Protein C and Related Proteins. Edinburgh, Churchill Livingstone, pp 160-181.
    • (1988) Protein C and Related Proteins , pp. 160-181
    • Broekmans, A.W.1    Conard, J.2
  • 9
    • 0028351510 scopus 로고
    • Frequency of a defective response to activated protein C in patients with a history of venous thrombosis
    • Cadroy Y, Sié P, Boneu B: 1994. Frequency of a defective response to activated protein C in patients with a history of venous thrombosis. Blood 83:2008-2009.
    • (1994) Blood , vol.83 , pp. 2008-2009
    • Cadroy, Y.1    Sié, P.2    Boneu, B.3
  • 10
    • 0028998202 scopus 로고
    • Factor V Leiden gene mutation and thrombin generation in relation to the development of acute stroke
    • Catto A, Carter A, Ireland H, et al.: 1995. Factor V Leiden gene mutation and thrombin generation in relation to the development of acute stroke. Arterioscler Thromb Vasc Biol 15:783-785.
    • (1995) Arterioscler Thromb Vasc Biol , vol.15 , pp. 783-785
    • Catto, A.1    Carter, A.2    Ireland, H.3
  • 11
    • 0021720421 scopus 로고
    • Recurrent thromboembolism in patients with a partial deficiency of protein S
    • Comp PC, Esmon CT: 1984. Recurrent thromboembolism in patients with a partial deficiency of protein S. N Engl J Med 311: 1525-1528.
    • (1984) N Engl J Med , vol.311 , pp. 1525-1528
    • Comp, P.C.1    Esmon, C.T.2
  • 12
    • 0343929872 scopus 로고
    • Risk of venous thrombosis in 51 women with resistance to activated protein C associated with factor V Leiden
    • Conard J, Trossaërt M, Horellou MH, Elalamy I, Cheloufi L, Samama MM: 1995. Risk of venous thrombosis in 51 women with resistance to activated protein C associated with factor V Leiden [abst]. Thromb Haemost 73:1375.
    • (1995) Thromb Haemost , vol.73 , pp. 1375
    • Conard, J.1    Trossaërt, M.2    Horellou, M.H.3    Elalamy, I.4    Cheloufi, L.5    Samama, M.M.6
  • 13
    • 0015909753 scopus 로고
    • Venous thromboembolism and other venous disease in the Tecumseh Community health study
    • Coon WW, Willis PW, Keller JB: 1973. Venous thromboembolism and other venous disease in the Tecumseh Community health study. Circulation 48:839-846.
    • (1973) Circulation , vol.48 , pp. 839-846
    • Coon, W.W.1    Willis, P.W.2    Keller, J.B.3
  • 14
    • 0028106532 scopus 로고
    • Plasma resistance to activated protein C in venous and arterial thrombosis
    • Cushman M, Bhushan F, Bovill E, Tracy R: 1994. Plasma resistance to activated protein C in venous and arterial thrombosis. Thromb Haemost 72:647.
    • (1994) Thromb Haemost , vol.72 , pp. 647
    • Cushman, M.1    Bhushan, F.2    Bovill, E.3    Tracy, R.4
  • 15
    • 0028832910 scopus 로고
    • The protein C anticoagulant system: Inherited defects as basis for venous thrombosis
    • Dahlbäck B: 1995. The protein C anticoagulant system: inherited defects as basis for venous thrombosis. Thromb Res 77:1-43.
    • (1995) Thromb Res , vol.77 , pp. 1-43
    • Dahlbäck, B.1
  • 16
    • 0028098218 scopus 로고
    • Inherited resistance to activated protein C is corrected by anticoagulant cofactor activity found to be a property of factor V
    • Dahlbäck B, Hildebrand B: 1994. Inherited resistance to activated protein C is corrected by anticoagulant cofactor activity found to be a property of factor V. Proc Natl Acad Sci USA 81:1396-1400.
    • (1994) Proc Natl Acad Sci USA , vol.81 , pp. 1396-1400
    • Dahlbäck, B.1    Hildebrand, B.2
  • 17
    • 0027446268 scopus 로고
    • Familial thrombophilia due to a previously unrecognized mechanism characterized by poor anticoagulant response to activated protein C: Prediction of a cofactor to activated protein C
    • Dahlbäck B, Carlsson M, Svensson PJ: 1993. Familial thrombophilia due to a previously unrecognized mechanism characterized by poor anticoagulant response to activated protein C: prediction of a cofactor to activated protein C. Proc Natl Acad Sci USA 90:1004-1008.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 1004-1008
    • Dahlbäck, B.1    Carlsson, M.2    Svensson, P.J.3
  • 18
    • 0029086642 scopus 로고
    • Biochemical and molecular aspects of the coagulation cascade
    • Davie EW: 1995. Biochemical and molecular aspects of the coagulation cascade. Thromb Haemost 74:1-6.
    • (1995) Thromb Haemost , vol.74 , pp. 1-6
    • Davie, E.W.1
  • 21
    • 0028651903 scopus 로고
    • Laboratory diagnosis of APC resistance: A critical evaluation of the test and the development of diagnostic criteria
    • De Ronde H, Bertina RM: 1994. Laboratory diagnosis of APC resistance: a critical evaluation of the test and the development of diagnostic criteria. Thromb Haemost 72:880-886.
    • (1994) Thromb Haemost , vol.72 , pp. 880-886
    • De Ronde, H.1    Bertina, R.M.2
  • 22
    • 0343058173 scopus 로고
    • Prevalence of venous thrombosis in pregnant women with APC resistance: A retrospective study
    • De Stefano V, Mastrangelo S, Paciaroni K, et al.: 1995. Prevalence of venous thrombosis in pregnant women with APC resistance: a retrospective study [abst]. Thromb Haemost 73:1375.
    • (1995) Thromb Haemost , vol.73 , pp. 1375
    • De Stefano, V.1    Mastrangelo, S.2    Paciaroni, K.3
  • 23
    • 0015538054 scopus 로고
    • President's address: The chair and venous thrombosis
    • Dexter L: 1973. President's address: the chair and venous thrombosis. Trans Am Clin Climatol Assoc 84:1-15.
    • (1973) Trans Am Clin Climatol Assoc , vol.84 , pp. 1-15
    • Dexter, L.1
  • 24
    • 0028888446 scopus 로고
    • Myocardial infarction, Arg506 to Gln factor V mutation, and activated protein C resistance
    • Emmerich J, Poirier O, Evans A, et al.: 1995. Myocardial infarction, Arg506 to Gln factor V mutation, and activated protein C resistance. Lancet 345:321.
    • (1995) Lancet , vol.345 , pp. 321
    • Emmerich, J.1    Poirier, O.2    Evans, A.3
  • 25
    • 0029073809 scopus 로고
    • Activated protein C resistance and graft occlusion after coronary artery bypass surgery
    • Eritsland J, Gjonnes G, Sandset PM, Seljeflot I, Arnesen H: 1995. Activated protein C resistance and graft occlusion after coronary artery bypass surgery. Thromb Res 79:223-226.
    • (1995) Thromb Res , vol.79 , pp. 223-226
    • Eritsland, J.1    Gjonnes, G.2    Sandset, P.M.3    Seljeflot, I.4    Arnesen, H.5
  • 26
    • 0026591793 scopus 로고
    • The protein C anticoagulant pathway
    • Esmon 1992: The protein C anticoagulant pathway. Arterioscler Thromb 12:135-145.
    • (1992) Arterioscler Thromb , vol.12 , pp. 135-145
    • Esmon1
  • 27
    • 0027742936 scopus 로고
    • Resistance to activated protein C in nine thrombophilic families: Interference in a protein S functional assay
    • Faioni EM, Franchi F, Asti D, Sacchi E, Bernardi F, Mannucci PM: 1993. Resistance to activated protein C in nine thrombophilic families: interference in a protein S functional assay. Thromb Haemost 70:1067-1071.
    • (1993) Thromb Haemost , vol.70 , pp. 1067-1071
    • Faioni, E.M.1    Franchi, F.2    Asti, D.3    Sacchi, E.4    Bernardi, F.5    Mannucci, P.M.6
  • 28
    • 0343929865 scopus 로고
    • Association between activated protein C resistance and postoperative deep vein thrombosis
    • Fauno P, Ravn HB, Lassen JF, Lund ED, Jensen ED: 1995. Association between activated protein C resistance and postoperative deep vein thrombosis [abst]. Thromb Haemost 73:1371.
    • (1995) Thromb Haemost , vol.73 , pp. 1371
    • Fauno, P.1    Ravn, H.B.2    Lassen, J.F.3    Lund, E.D.4    Jensen, E.D.5
  • 29
    • 0028911122 scopus 로고
    • Activated protein C resistance in cases of cerebral infarction
    • Forsyth PD, Dolan G: 1995. Activated protein C resistance in cases of cerebral infarction. Lancet 345:795.
    • (1995) Lancet , vol.345 , pp. 795
    • Forsyth, P.D.1    Dolan, G.2
  • 30
    • 0024292694 scopus 로고
    • The molecular basis of blood coagulation
    • Furie B, Furie BC: 1988. The molecular basis of blood coagulation. Cell 53:505-518.
    • (1988) Cell , vol.53 , pp. 505-518
    • Furie, B.1    Furie, B.C.2
  • 31
    • 0029050714 scopus 로고
    • Incidence of activated protein C resistance caused by the ARG 506 GLN mutation in factor V in 113 unrelated symptomatic protein C-deficient patients
    • Gandrille S, Greengard JS, Alhenc-Gelas M, et al.: 1995. Incidence of activated protein C resistance caused by the ARG 506 GLN mutation in factor V in 113 unrelated symptomatic protein C-deficient patients. Blood 86:219-224.
    • (1995) Blood , vol.86 , pp. 219-224
    • Gandrille, S.1    Greengard, J.S.2    Alhenc-Gelas, M.3
  • 32
    • 84965091000 scopus 로고
    • The incidence of venous thrombosis and its sequelae in certain districts in Sweden
    • Gjöres JE: 1956. The incidence of venous thrombosis and its sequelae in certain districts in Sweden. Acta Chir Scand (Suppl) 206:1-88.
    • (1956) Acta Chir Scand (Suppl) , vol.206 , pp. 1-88
    • Gjöres, J.E.1
  • 33
    • 0002596183 scopus 로고
    • Epidemiology of pulmonary embolism and deep vein thrombosis
    • Bloom AL, Forbes CD, Thomas DP, Tuddenham EGD, eds. Edinburgh, Churchill Livingstone
    • Goldhaber SZ: 1994. Epidemiology of pulmonary embolism and deep vein thrombosis. In Bloom AL, Forbes CD, Thomas DP, Tuddenham EGD, eds. Haemostasis and Thrombosis. Edinburgh, Churchill Livingstone, pp 1327-1333.
    • (1994) Haemostasis and Thrombosis , pp. 1327-1333
    • Goldhaber, S.Z.1
  • 34
    • 0027999556 scopus 로고
    • Brief report: Variability of thrombosis among homozygous siblings with resistance to activated protein C due to an Arg→Gln mutation in the gene for factor V
    • Greengard JS, Eichinger S, Griffin JH, Bauer KA: 1994a. Brief report: variability of thrombosis among homozygous siblings with resistance to activated protein C due to an Arg→Gln mutation in the gene for factor V. N Engl J Med 331:1559-1562.
    • (1994) N Engl J Med , vol.331 , pp. 1559-1562
    • Greengard, J.S.1    Eichinger, S.2    Griffin, J.H.3    Bauer, K.A.4
  • 37
    • 0027428481 scopus 로고
    • Anticoagulant protein C pathway defective in a majority of thrombophilic patients
    • Griffin JH, Evatt BL, Wideman C, Fernandez JA: 1993. Anticoagulant protein C pathway defective in a majority of thrombophilic patients. Blood 82:1989-1993.
    • (1993) Blood , vol.82 , pp. 1989-1993
    • Griffin, J.H.1    Evatt, B.L.2    Wideman, C.3    Fernandez, J.A.4
  • 38
    • 0028326025 scopus 로고
    • The prevalence of poor anticoagulant response to activated protein C (APC resistance) among patients suffering from stroke or venous thrombosis and among healthy subjects
    • Halbmayer WM, Haushofer A, Schön R, Fischer M: 1994. The prevalence of poor anticoagulant response to activated protein C (APC resistance) among patients suffering from stroke or venous thrombosis and among healthy subjects. Blood Coagul Fibrinol 5:51-57.
    • (1994) Blood Coagul Fibrinol , vol.5 , pp. 51-57
    • Halbmayer, W.M.1    Haushofer, A.2    Schön, R.3    Fischer, M.4
  • 39
    • 0029154596 scopus 로고
    • Population differences in the frequency of the factor V Leiden variant among people with clinically symptomatic protein c deficiency
    • Hallam PJ, Millar DS, Krawczak M, Kakkar VV, Cooper DN: 1995. Population differences in the frequency of the factor V Leiden variant among people with clinically symptomatic protein c deficiency. J Med Genet 32:543-545.
    • (1995) J Med Genet , vol.32 , pp. 543-545
    • Hallam, P.J.1    Millar, D.S.2    Krawczak, M.3    Kakkar, V.V.4    Cooper, D.N.5
  • 40
    • 0029048665 scopus 로고
    • Activated protein C resistance: Molecular mechanisms based on studies using purified Gln506-factor V
    • Heeb MJ, Kojima Y, Greengard JS, Griffin JH: 1995. Activated protein C resistance: molecular mechanisms based on studies using purified Gln506-factor V. Blood 85: 3405-3411.
    • (1995) Blood , vol.85 , pp. 3405-3411
    • Heeb, M.J.1    Kojima, Y.2    Greengard, J.S.3    Griffin, J.H.4
  • 41
    • 0025241268 scopus 로고
    • Deficiencies of coagulation-inhibiting and fibrinolytic proteins in outpatients with deep-vein thrombosis
    • Heijboer H, Brandjes D, Büller HR, Sturk A, ten Cate JW: 1990. Deficiencies of coagulation-inhibiting and fibrinolytic proteins in outpatients with deep-vein thrombosis. N Engl J Med 323:1512-1516.
    • (1990) N Engl J Med , vol.323 , pp. 1512-1516
    • Heijboer, H.1    Brandjes, D.2    Büller, H.R.3    Sturk, A.4    Ten Cate, J.W.5
  • 42
    • 0008366171 scopus 로고
    • Frequency of point mutation in factor V gene (1,691 G/A), which is associated with resistance to activated protein C, in coronary artery disease patients
    • Heinrich J, Schulte H, Funke H, Schönfeld R, Köhler E, Assmann G: 1995. Frequency of point mutation in factor V gene (1,691 G/A), which is associated with resistance to activated protein C, in coronary artery disease patients [abst]. Thromb Haemost 73:1125.
    • (1995) Thromb Haemost , vol.73 , pp. 1125
    • Heinrich, J.1    Schulte, H.2    Funke, H.3    Schönfeld, R.4    Köhler, E.5    Assmann, G.6
  • 43
    • 0029162113 scopus 로고
    • Resistance to activated protein C as a basis for venous thromboembolism associated with pregnancy and oral contraceptives
    • in press
    • Hellgren M, Svensson PJ, Dahlbäck B: 1995. Resistance to activated protein C as a basis for venous thromboembolism associated with pregnancy and oral contraceptives. Am J Obstet Gynecol (in press).
    • (1995) Am J Obstet Gynecol
    • Hellgren, M.1    Svensson, P.J.2    Dahlbäck, B.3
  • 44
    • 0028110974 scopus 로고
    • Myocardial infarction associated with homozygous resistance to activated protein C
    • Holm J, Zöller B, Svensson PJ, Berntorp E, Erhardt L, Dahlbäck B: 1994. Myocardial infarction associated with homozygous resistance to activated protein C. Lancet 344: 952-953.
    • (1994) Lancet , vol.344 , pp. 952-953
    • Holm, J.1    Zöller, B.2    Svensson, P.J.3    Berntorp, E.4    Erhardt, L.5    Dahlbäck, B.6
  • 45
    • 0030032237 scopus 로고    scopus 로고
    • Prevalence of factor V gene mutation among myocardial infarction patients and healthy controls higher in Sweden than in other countries
    • in press
    • Holm J, Zöller B, Svensson PJ, Berntorp E, Erhardt L, Dahlbäck B: 1996. Prevalence of factor V gene mutation among myocardial infarction patients and healthy controls higher in Sweden than in other countries. J Int Med (in press).
    • (1996) J Int Med
    • Holm, J.1    Zöller, B.2    Svensson, P.J.3    Berntorp, E.4    Erhardt, L.5    Dahlbäck, B.6
  • 46
    • 0029025477 scopus 로고
    • Factor V Leiden and thrombophilia
    • Hopmeier P, Krugluger W: 1995. Factor V Leiden and thrombophilia. N Engl J Med 332:1381-1382.
    • (1995) N Engl J Med , vol.332 , pp. 1381-1382
    • Hopmeier, P.1    Krugluger, W.2
  • 47
    • 0013417175 scopus 로고
    • Factor V Leiden as an independent risk factor for thrombosis in antithrombin deficiency type II: Heparin binding site
    • Ireland H, Bayston T, Chowdhury V, et al.: 1995. Factor V Leiden as an independent risk factor for thrombosis in antithrombin deficiency type II: heparin binding site [abst]. Thromb Haemost 73:1361.
    • (1995) Thromb Haemost , vol.73 , pp. 1361
    • Ireland, H.1    Bayston, T.2    Chowdhury, V.3
  • 48
    • 0028110027 scopus 로고
    • The mechanism of inactivation of human factor V and human factor Va by activated protein C
    • Kalafatis M, Rand MD, Mann KG: 1994. The mechanism of inactivation of human factor V and human factor Va by activated protein C. J Biol Chem 269:31,869-31,880.
    • (1994) J Biol Chem , vol.269 , pp. 31869-31880
    • Kalafatis, M.1    Rand, M.D.2    Mann, K.G.3
  • 49
    • 0028939318 scopus 로고
    • Characterization of the molecular defect in factor VR506Q
    • Kalafatis M, Bertina RM, Rand MD, Mann KG: 1995. Characterization of the molecular defect in factor VR506Q. J Biol Chem 270:4053-4057.
    • (1995) J Biol Chem , vol.270 , pp. 4053-4057
    • Kalafatis, M.1    Bertina, R.M.2    Rand, M.D.3    Mann, K.G.4
  • 50
    • 0029058581 scopus 로고
    • The incidence of activated protein C resistance among patients with deep vein thrombosis and healthy subjects in Osaka
    • Kambayashi J, Fujimura H, Kawasaki T, et al.: 1995. The incidence of activated protein C resistance among patients with deep vein thrombosis and healthy subjects in Osaka. Thromb Res 79:227-229.
    • (1995) Thromb Res , vol.79 , pp. 227-229
    • Kambayashi, J.1    Fujimura, H.2    Kawasaki, T.3
  • 51
    • 0023918199 scopus 로고
    • Blood coagulation factors V and VIII: Structural and functional similarities and their relationship to hemorrhagic and thrombotic disorders
    • Kane WH, Davie EW: 1988. Blood coagulation factors V and VIII: structural and functional similarities and their relationship to hemorrhagic and thrombotic disorders. Blood 71:539-555.
    • (1988) Blood , vol.71 , pp. 539-555
    • Kane, W.H.1    Davie, E.W.2
  • 52
    • 0028000665 scopus 로고
    • Activated protein C resistance as an additional risk factor for thrombosis in protein C-deficient families
    • Koeleman BPC, Reitsma PH, Allaart CF, Bertina RM: 1994. Activated protein C resistance as an additional risk factor for thrombosis in protein C-deficient families. Blood 84:1031-1035.
    • (1994) Blood , vol.84 , pp. 1031-1035
    • Koeleman, B.P.C.1    Reitsma, P.H.2    Allaart, C.F.3    Bertina, R.M.4
  • 53
    • 0028988219 scopus 로고
    • Arg506Gln factor V mutation (factor V Leiden) in patients with ischaemic cerebrovascular disease and survivors of myocardial infarction
    • Kontula K, Ylikorkala A, Miettinen H, et al.: 1995. Arg506Gln factor V mutation (factor V Leiden) in patients with ischaemic cerebrovascular disease and survivors of myocardial infarction. Thromb Haemost 73:558-560.
    • (1995) Thromb Haemost , vol.73 , pp. 558-560
    • Kontula, K.1    Ylikorkala, A.2    Miettinen, H.3
  • 55
    • 0028964841 scopus 로고
    • Portal vein thrombosis and factor V Arg 506 to Gln mutation
    • Levoir D, Emmerich J, Alhenc-Gelas M, et al.: 1995. Portal vein thrombosis and factor V Arg 506 to Gln mutation. Thromb Haemost 73:550-551.
    • (1995) Thromb Haemost , vol.73 , pp. 550-551
    • Levoir, D.1    Emmerich, J.2    Alhenc-Gelas, M.3
  • 56
    • 0029651797 scopus 로고
    • Budd-Chiari syndrome and factor V Leiden mutation
    • Mahmoud AEA, Wilde JT, Elias E: 1995. Budd-Chiari syndrome and factor V Leiden mutation. Lancet 345:526.
    • (1995) Lancet , vol.345 , pp. 526
    • Mahmoud, A.E.A.1    Wilde, J.T.2    Elias, E.3
  • 57
    • 0028765167 scopus 로고
    • Bad blood by mutation
    • Majerus PW: 1994. Bad blood by mutation. Nature 369:14-15.
    • (1994) Nature , vol.369 , pp. 14-15
    • Majerus, P.W.1
  • 58
    • 0026695880 scopus 로고
    • Thromboembolic disease: Critical evaluation of laboratory investigation
    • Malm J, Laurell M, Nilsson IM, Dahlbäck B: 1992. Thromboembolic disease: critical evaluation of laboratory investigation. Thromb Haemost 68:7-13.
    • (1992) Thromb Haemost , vol.68 , pp. 7-13
    • Malm, J.1    Laurell, M.2    Nilsson, I.M.3    Dahlbäck, B.4
  • 59
    • 0025244937 scopus 로고
    • Neonatal purpura fulminans due to homozygous protein C or protein S deficiencies
    • Marlar RA, Neumann A: 1990. Neonatal purpura fulminans due to homozygous protein C or protein S deficiencies. Semin Thromb Hemost 16:299-309.
    • (1990) Semin Thromb Hemost , vol.16 , pp. 299-309
    • Marlar, R.A.1    Neumann, A.2
  • 60
    • 0023233223 scopus 로고
    • Absence of thrombosis in subjects with heterozygous protein C deficiency
    • Miletich JP, Sherman L, Broze GJ Jr: 1987. Absence of thrombosis in subjects with heterozygous protein C deficiency. N Engl J Med 317:991-996.
    • (1987) N Engl J Med , vol.317 , pp. 991-996
    • Miletich, J.P.1    Sherman, L.2    Broze G.J., Jr.3
  • 61
    • 0028902044 scopus 로고
    • Mutation in coagulation factor V associated with resistance to activated protein C in patients with coronary artery disease
    • März W, Seydewitz H, Winkelmann B, Chen M, Nauck M: 1995. Mutation in coagulation factor V associated with resistance to activated protein C in patients with coronary artery disease. Lancet 345:526-527.
    • (1995) Lancet , vol.345 , pp. 526-527
    • März, W.1    Seydewitz, H.2    Winkelmann, B.3    Chen, M.4    Nauck, M.5
  • 63
  • 64
    • 0023851758 scopus 로고
    • Tissue factor and hemostasis
    • Nemerson Y: 1988. Tissue factor and hemostasis. Blood 71:1-8.
    • (1988) Blood , vol.71 , pp. 1-8
    • Nemerson, Y.1
  • 65
    • 0013425781 scopus 로고
    • Factor V (FV) Leiden mutation (APC resistance) increases the risk for venous thromboembolism in patients with a gene defect of the protein C (PC) or protein S (PS) gene
    • Pabinger I, Mustafa S, Rintelen C, Kyrle PA, Lechner K, Mannhalter C: 1995. Factor V (FV) Leiden mutation (APC resistance) increases the risk for venous thromboembolism in patients with a gene defect of the protein C (PC) or protein S (PS) gene [abst]. Thromb Haemost 73:1361.
    • (1995) Thromb Haemost , vol.73 , pp. 1361
    • Pabinger, I.1    Mustafa, S.2    Rintelen, C.3    Kyrle, P.A.4    Lechner, K.5    Mannhalter, C.6
  • 66
    • 4243629916 scopus 로고
    • APC resistance: Factor V is not involved in proteolytic inactivation of factor VIII by activated protein C
    • Pötzsch B, Rehling T, Knedla A, Müller-Berghaus G: 1995. APC resistance: factor V is not involved in proteolytic inactivation of factor VIII by activated protein C [abst]. Thromb Haemost 73:1121.
    • (1995) Thromb Haemost , vol.73 , pp. 1121
    • Pötzsch, B.1    Rehling, T.2    Knedla, A.3    Müller-Berghaus, G.4
  • 67
    • 0343494104 scopus 로고
    • Combined hereditary APC resistance and ATIII type II deficiency associated with venous thrombosis
    • Radtke KP, Lane DA, Greengard JS, Ehrenforth S, Griffin JH: 1995. Combined hereditary APC resistance and ATIII type II deficiency associated with venous thrombosis [abst]. Thromb Haemost 73:1377.
    • (1995) Thromb Haemost , vol.73 , pp. 1377
    • Radtke, K.P.1    Lane, D.A.2    Greengard, J.S.3    Ehrenforth, S.4    Griffin, J.H.5
  • 68
    • 0028810738 scopus 로고
    • World distribution of factor V Leiden
    • Rees DC, Cox M, Clegg JB: 1995. World distribution of factor V Leiden. Lancet 346: 1133-1134.
    • (1995) Lancet , vol.346 , pp. 1133-1134
    • Rees, D.C.1    Cox, M.2    Clegg, J.B.3
  • 69
    • 0026072398 scopus 로고
    • The spectrum of genetic defects in a panel of 40 Dutch families with symptomatic protein C deficiency type I: Heterogeneity and founder effects
    • Reitsma PH, Poort SR, Allaart CF, Briët E, Bertina RM: 1991. The spectrum of genetic defects in a panel of 40 Dutch families with symptomatic protein C deficiency type I: heterogeneity and founder effects. Blood 78:890-894.
    • (1991) Blood , vol.78 , pp. 890-894
    • Reitsma, P.H.1    Poort, S.R.2    Allaart, C.F.3    Briët, E.4    Bertina, R.M.5
  • 70
    • 0028910906 scopus 로고
    • Mutation in the gene coding for coagulation factor V and the risk of myocardial infarction, stroke, and venous thrombosis in apparently healthy men
    • Ridker PM, Hennekens CH, Lindpaintner K, Stampfer MJ, Eisenberg PR, Miletich JP: 1995. Mutation in the gene coding for coagulation factor V and the risk of myocardial infarction, stroke, and venous thrombosis in apparently healthy men. N Engl J Med 332:912-917.
    • (1995) N Engl J Med , vol.332 , pp. 912-917
    • Ridker, P.M.1    Hennekens, C.H.2    Lindpaintner, K.3    Stampfer, M.J.4    Eisenberg, P.R.5    Miletich, J.P.6
  • 71
    • 0028931717 scopus 로고
    • High risk of thrombosis in patients homozygous for factor V Leiden (activated protein C resistance)
    • Rosendaal FR, Koster T, Vandenbroucke JP, Reitsma PH: 1995. High risk of thrombosis in patients homozygous for factor V Leiden (activated protein C resistance). Blood 85: 1504-1508.
    • (1995) Blood , vol.85 , pp. 1504-1508
    • Rosendaal, F.R.1    Koster, T.2    Vandenbroucke, J.P.3    Reitsma, P.H.4
  • 72
    • 0028110455 scopus 로고
    • Resistance to activated protein C and risk of premature myocardial infarction
    • Samani N, Lodwick D, Martin D, Kimber P: 1994. Resistance to activated protein C and risk of premature myocardial infarction. Lancet 344:1709-1710.
    • (1994) Lancet , vol.344 , pp. 1709-1710
    • Samani, N.1    Lodwick, D.2    Martin, D.3    Kimber, P.4
  • 74
    • 0021343348 scopus 로고
    • Homozygous protein C deficiency manifested by massive thrombosis in the newborn
    • Seligsohn U, Berger A, Abend A, et al.: 1984 Homozygous protein C deficiency manifested by massive thrombosis in the newborn. N Engl J Med 310:559-562.
    • (1984) N Engl J Med , vol.310 , pp. 559-562
    • Seligsohn, U.1    Berger, A.2    Abend, A.3
  • 75
    • 0028290275 scopus 로고
    • Factor V and protein S as synergistic cofactors to activated protein C in degradation of factor VIIIa
    • Shen L, Dahlbäck B: 1994. Factor V and protein S as synergistic cofactors to activated protein C in degradation of factor Villa. J Biol Chem 269:18,735-18,738.
    • (1994) J Biol Chem , vol.269 , pp. 18
    • Shen, L.1    Dahlbäck, B.2
  • 76
    • 0028305045 scopus 로고
    • Blood coagulation factor Va abnormality associated with resistance to activated protein C in venous thrombophilia
    • Sun X, Evatt BL, Griffin JH: 1994. Blood coagulation factor Va abnormality associated with resistance to activated protein C in venous thrombophilia. Blood 83:3120-3125.
    • (1994) Blood , vol.83 , pp. 3120-3125
    • Sun, X.1    Evatt, B.L.2    Griffin, J.H.3
  • 77
    • 0028098210 scopus 로고
    • Resistance to activated protein C as a basis for venous thrombosis
    • Svensson PJ, Dahlbäck B: 1994. Resistance to activated protein C as a basis for venous thrombosis. N Engl J Med 330:517-521.
    • (1994) N Engl J Med , vol.330 , pp. 517-521
    • Svensson, P.J.1    Dahlbäck, B.2
  • 79
    • 0028951045 scopus 로고
    • Premature ischaemic heart disease and the gene for coagulation factor V
    • Van Bockxmeer FM, Baker RI, Taylor RR: 1995. Premature ischaemic heart disease and the gene for coagulation factor V. Nat Med 1:185.
    • (1995) Nat Med , vol.1 , pp. 185
    • Van Bockxmeer, F.M.1    Baker, R.I.2    Taylor, R.R.3
  • 80
    • 0342623881 scopus 로고
    • Interaction of factor V Leiden with inherited antithrombin deficiency
    • Van Boven HH, Reitsma PH, Rosendaal FR, et al.: 1995. Interaction of factor V Leiden with inherited antithrombin deficiency. [abst] Thromb Haemost 73: 1256.
    • (1995) Thromb Haemost , vol.73 , pp. 1256
    • Van Boven, H.H.1    Reitsma, P.H.2    Rosendaal, F.R.3
  • 81
    • 0028029477 scopus 로고
    • Increased risk of venous thrombosis in oral-contraceptive users who are carriers of factor V Leiden mutation
    • Vandenbroucke JP, Koster T, Briët E, Reitsma PH, Bertina RM, Rosendaal FR: 1994. Increased risk of venous thrombosis in oral-contraceptive users who are carriers of factor V Leiden mutation. Lancet 344: 1453-1457.
    • (1994) Lancet , vol.344 , pp. 1453-1457
    • Vandenbroucke, J.P.1    Koster, T.2    Briët, E.3    Reitsma, P.H.4    Bertina, R.M.5    Rosendaal, F.R.6
  • 82
    • 0028922594 scopus 로고
    • Influence of factor V and factor Va on APC-induced cleavage of human factor VIII
    • Vàradi K, Rosing J, Tans G, Schwarz HP: 1995. Influence of factor V and factor Va on APC-induced cleavage of human factor VIII. Thromb Haemost 73:730-731.
    • (1995) Thromb Haemost , vol.73 , pp. 730-731
    • Vàradi, K.1    Rosing, J.2    Tans, G.3    Schwarz, H.P.4
  • 83
    • 0343929861 scopus 로고
    • Prospective study on activates protein C resistance in patients with acute myocardial infarction
    • Viigimaa M, Saareoja Y: 1995. Prospective study on activates protein C resistance in patients with acute myocardial infarction [abst]. Thromb Haemost 73:1374.
    • (1995) Thromb Haemost , vol.73 , pp. 1374
    • Viigimaa, M.1    Saareoja, Y.2
  • 84
    • 0028243401 scopus 로고
    • Association of idiopathic thromboembolism with single point mutation at Arg506 of factor V
    • Voorberg J, Roelse J, Koopman R, et al.: 1994. Association of idiopathic thromboembolism with single point mutation at Arg506 of factor V. Lancet 343:1535-1536.
    • (1994) Lancet , vol.343 , pp. 1535-1536
    • Voorberg, J.1    Roelse, J.2    Koopman, R.3
  • 85
    • 0028291210 scopus 로고
    • Linkage between inherited resistance to activated protein C and factor V gene mutation in venous thrombosis
    • Zöller B, Dahlbäck B: 1994. Linkage between inherited resistance to activated protein C and factor V gene mutation in venous thrombosis. Lancet 343:1536-1538.
    • (1994) Lancet , vol.343 , pp. 1536-1538
    • Zöller, B.1    Dahlbäck, B.2
  • 86
    • 0028037137 scopus 로고
    • Identification of the same factor V gene mutation in 47 out of 50 thrombosis-prone families with inherited resistance to activated protein C
    • Zöller B, Svensson PJ, He X, Dahlbäck B: 1994. Identification of the same factor V gene mutation in 47 out of 50 thrombosis-prone families with inherited resistance to activated protein C. J Clin Invest 94:2521-2524.
    • (1994) J Clin Invest , vol.94 , pp. 2521-2524
    • Zöller, B.1    Svensson, P.J.2    He, X.3    Dahlbäck, B.4
  • 87
    • 0029016883 scopus 로고
    • Resistance to activated protein C as an additional genetic risk factor in hereditary deficiency of protein S
    • Zöller B, Berntsdotter A, Garcia de Frutos P, Dahlbäck B: 1995a. Resistance to activated protein C as an additional genetic risk factor in hereditary deficiency of protein S. Blood 85:3518-3523.
    • (1995) Blood , vol.85 , pp. 3518-3523
    • Zöller, B.1    Berntsdotter, A.2    Garcia De Frutos, P.3    Dahlbäck, B.4
  • 88
    • 0029022665 scopus 로고
    • Homozygous APC-resistance combined with inherited type I protein S deficiency in a young boy with severe thrombotic disease
    • Zöller B, He X, Dahlbäck B: 1995b. Homozygous APC-resistance combined with inherited type I protein S deficiency in a young boy with severe thrombotic disease. Thromb Haemost 73:743-745.
    • (1995) Thromb Haemost , vol.73 , pp. 743-745
    • Zöller, B.1    He, X.2    Dahlbäck, B.3
  • 89
    • 0029878085 scopus 로고    scopus 로고
    • Elevated levels of prothrombin activation fragment 1+2 in plasma from patients with heterozygous Arg 506 to Gln mutation in the factor V gene (APC resistance) and/or inherited protein S deficiency
    • in press
    • Zöller B, Holm J, Svensson PJ, Dahlbäck B: 1996. Elevated levels of prothrombin activation fragment 1+2 in plasma from patients with heterozygous Arg 506 to Gln mutation in the factor V gene (APC resistance) and/or inherited protein S deficiency. Thromb Haemost (in press).
    • (1996) Thromb Haemost
    • Zöller, B.1    Holm, J.2    Svensson, P.J.3    Dahlbäck, B.4


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