Inefficient mismatch repair: Genetic defects and down regulation

Journal of Genetics

Volumn 78, Issue 1, 1999, Pages 21-28

  Brégeon, Damien ^a   Matic, Ivan ^a   Radman, Miroslav ^a,b   Taddei, François ^a,c  

^a INSTITUT JACQUES MONOD   (France)

^b UNIVERSITÉ PARIS DESCARTES   (France)

^c INSERM   (France)

Author keywords

Cancer; Escherichia coli; Evolution; Mismatch repair; Mutator

Indexed keywords

EID: 4243248242     PISSN: 00221333     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02994699     Document Type: Article

References (68)

1. Chao L. and Cox E. C. 1983 Competition between high and low mutating strains of Escherichia coli. Evolution 37, 125-134.
2. Conrad S. E., Dussik K. T. and Siegel E. C. 1976 Bacteriophage Mu-1-induced mutation to mutT in Escherichia coli. J. Bacteriol. 125, 1018-1023.
3. Cox E. C. and Gibson T. G. 1974 Selection for high mutation rates in chemostats. Genetics 77, 169-184.
4. Damagnez V., Doutriaux M. P. and Radman M. 1989 Saturation of mismatch repair in the mutD5 mutator strain of Escherichia coli. J. Bacteriol. 171, 4494-4497.
5. Degnen G. E. and Cox E. C. 1974 Conditional mutator gene in Escherichia coli: isolation, mapping, and effector studies. J. Bacteriol. 117, 477-487.
6. Drake J. W. 1991 A constant rate of spontaneous mutation in DNA-based microbes. Proc. Natl. Acad. Sci. USA 88, 7160-7164.
7. Eisen J. A. 1998 Evolution of the MutS family of proteins: gene duplication, functional divergence and gene loss. Nucl. Acids Res. 26, 4291-4300.
8. Feng G., Tsui H. C. and Winkler M. E. 1996 Depletion of the cellular amounts of the MutS and MutH methyl-directed mismatch repair proteins in stationary-phase Escherichia coli K-12 cells. J. Bacteriol. 178, 2388-2396.
9. Foster P. L. 1998 Adaptive mutation: has the unicorn landed? Genetics 148, 1453-1459.
10. Foster P. L. and Rosche W. A. 1999 Mechanisms of mutation in non-dividing cells: Insights from the study of adaptive mutation in Escherichia coli. Ann. N. Y. Acad. Sci. (in press).
11. Foster P. L. and Trimarchi J. M. 1994 Adaptive reversion of a frameshift mutation in Escherichia coli by simple base deletions in homopolymeric runs. Science 265, 407-409.
12. Friedberg E. C., Walker G. C. and Siede W. 1995 DNA repair and mutagenesis. ASM Press, Washington, DC.
13. Gibson T. C., Scheppe M. L. and Cox E. C. 1970 Fitness of an E. coli mutator gene. Science 169, 686-688.
14. Glickman B. W. and Radman M. 1980 Escherichia coli mutator mutants deficient in methylation-instructed DNA mismatch correction. Proc. Natl. Acad. Sci. USA 77, 1063-1067.
15. Goldstein A. and Smoot J. S. 1955 A strain of Escherichia coli with an unusually high rate of auxotrophic mutation. J. Bacteriol. 70, 588-595.
16. Gross M. D. and Siegel E. C. 1981 Incidence of mutator strains in Escherichia coli and coliforms in nature. Mutat. Res. 91, 107-110.
17. Hanahan D. 1983 Studies on transformation of Escherichia coli with plasmids. J. Mol. Biol. 166, 557-580.
18. Harris R. S., Feng G., Ross K. J., Sidhu R., Thulin C., Longerich S., Szigety S. K., Winkler M. E. and Rosenberg S. M. 1997 Mismatch repair protein MutL becomes limiting during stationary-phase mutation. Genes Dev. 11, 2426-2437.
19. Hoess R. H. and Herman R. K. 1975 Isolation and characterization of mutator strains of E. coli K-12. J. Bacteriol. 122, 474-484.
20. Horiuchi T., Maki H. and Sekiguchi M. 1978 A new conditional lethal mutator (dnaQ49) in Escherichia coli K-12. Mol. Gen. Genet. 163, 277-283.
21. Horst J. P., Wu T. H. and Marinus M. G. 1999 Escherichia coli mutator genes. Trends Microbiol. 7, 29-36.
22. Inouye M. and Inouye S. 1992 Retrons and multicopy single-stranded DNA. J. Bacteriol. 174, 2419-2424.
23. Jyssum K. 1960 Observation of two types of genetic instability in Escherichia coli. Acta. Pathol. Microbiol. Immunol. Scand. 48, 113-120.
24. Kimura M. 1967 On the evolutionary adjustment of spontaneous mutation rates. Genet. Res. 9, 23-34.
25. Kunkel T. A. and Loeb L. A. 1984 Mutational specificity of depurination. Proc. Natl. Acad. Sci. USA 81, 1494-1498.
26. LeClerc J. E., Li B., Payne W. L. and Cebula T. A. 1996 High mutation frequencies among Escherichia coli and Salmonella pathogens. Science 274, 1208-1211.
27. LeClerc J. E., Payne W. L., Kupchella E. and Cebula T. A. 1998 Detection of mutator subpopulations in Salmonella typhimurium LT2 by reversion of his alleles. Mutat. Res. 400, 89-97.
28. Leigh E. G. 1973 The evolution of mutation rates. Genetics 73, 1-18.
29. Liberfarb R. M. and Bryson V. 1970 Isolation, characterization, and genetic analysis of mutator genes in Escherichia coli B and K-12. J. Bacteriol. 104, 363-375.
30. Loeb L. A. 1998 Cancer cells exhibit a mutator phenotype. Adv. Cancer Res. 72, 25-56.
31. Maas W. K., Wang C., Lima T., Zubay G. and Lim D. 1994 Multicopy single-stranded DNAs with mismatched base pairs are mutagenic in Escherichia coli. Mol. Microbiol. 14, 437-441.
32. Maas W. K., Wang C., Lima T., Hach A. and Lim D. 1996 Multicopy single-stranded DNA of Escherichia coli enhances mutation and recombination frequencies by titrating MutS protein. Mol. Microbiol. 19, 505-509.
33. Magnasco M. O. and Thaler D. S. 1996 Changing the pace of evolution. Phys. Lett. A221, 287-292.
34. Mao E. F., Lane L., Lee J. and Miller J. H. 1997 Proliferation of mutators in a cell population. J. Bacteriol. 179, 417-422.
35. Matic I., Rayssiguier C. and Radman M. 1995 Interspecies gene exchange in bacteria: The role of SOS and mismatch repair systems in evolution of species. Cell 80, 507-515.
36. Matic I., Radman M., Taddei F., Picard B., Doit C., Bingen E. et al. 1997 Highly variable mutation rates in commensal and pathogenic E. coli. Science 277, 1833-1834.
37. Mergeay M. and Gerits J. 1983 Transduction of Escherichia coli trp genes in Salmonella typhimurium and effect of N-methyl-N′-nitro-N-nitrosoguanidine on transduction with heterogenotic DNA. J. Gen. Microbiol. 129, 321-335.
38. Miller J. H. 1996 Spontaneous mutators in bacteria: insight into pathways of mutagenesis and repair. Annu. Rev. Microbiol. 50, 625-643.
39. Modrich P. and Lahue R. 1996 Mismatch repair in replication fidelity, genetic recombination, and cancer biology. Annu. Rev. Biochem. 65, 101-133.
40. Moxon E. R., Rainey P. B., Nowak M. A. and Lenski R. E. 1994 Adaptive evolution of highly mutable loci in pathogenic bacteria. Curr. Biol. 4, 24-33.
41. Ninio J. 1991 Transient mutators: a semiquantitative analysis of the influence of translation and transcription errors on mutation rates. Genetics 129, 957-962.
42. Pang P. P., Lundberg A. S. and Walker G. C. 1985 Identification and characterization of the mutL and mutS gene products of Salmonella typhimurium LT2. J. Bacteriol. 163, 1007-1015.
43. Radman M., Dohet C., Bourguignon M.-F., Doubleday O. P. and Lecomte P. 1981 High fidelity devices in the reproduction of DNA. In Chromosome damage and repair (ed. E. Seeberg and K. Kleppe), pp. 431-445. Plenum, New York.
44. Radman M., Matic I., Halliday J. A. and Taddei F. 1995 Editing DNA replication and recombination by mismatch repair: from bacterial genetics to mechanisms of predisposition to cancer in humans. Philos. Trans. R. Soc. London B347, 97-103.
45. Rayssiguier C., Thaler D. S. and Radman M. 1989 The barrier to recombination between Escherichia coli and Salmonella typhimurium is disrupted in mismatch-repair mutants. Nature 342, 396-401.
46. Richards B., Zhang H., Phear G. and Meuth M. 1997 Conditional mutator phenotypes in hMSH2-deficient tumor cell lines. Science 277, 1523-1526.
47. Rosenberg S., Longerich S., Gee P. and Harris R. 1994 Adaptive mutation by deletions in small mononucleotide repeats. Science 265, 405-407.
48. Rosenberg S. M., Thulin C. and Harris R. S. 1998 Transient and heritable mutators in adaptive evolution in the lab and in nature. Genetics 148, 1559-1566.
49. Schaaper R. M. 1988 Mechanisms of mutagenesis in the Escherichia coli mutator mutD5: role of DNA mismatch repair. Proc. Natl. Acad. Sci. USA 85, 8126-8130.
50. Schaaper R. M. 1989 Escherichia coli mutator mutD5 is defective in the mutHLS pathway of mismatch repair. Genetics 121, 205-212.
51. Schaaper R. M. and Radman M. 1989 The extreme mutator effect of Escherichia coli mutD5 results from saturation of mismatch repair by excessive DNA replication errors. EMBO J. 8, 3511-3516.
52. Shanabruch W. G., Behlau I. and Walker G. C. 1981 Spontaneous mutators of Salmonella typhimurium LT2 generated by insertion of transposable elements. J. Bacteriol 147, 827-835.
53. Siegel E. C. 1983 The Escherichia coli uvrD gene is not inducible by DNA damage. Mol. Gen. Genet. 191, 397-400.
54. Siegel E. C. and Bryson V. 1964 Selection of resistant strains of Escherichia coli by antibiotics and antibacterial agents: role of normal and mutator strain. In Antimicrobial agents and chemotherapy 1963 (ed. J. C. Sylvester), pp. 629-634. American Society for Microbiology, Ann Arbor.
55. Siegel E. C., Wain S. L., Meltzer S. F., Binion M. L. and Steinberg J. L. 1982 Mutator mutations in Escherichia coli induced by the insertion of phage mu and the transposable resistance elements Tn5 and Tn10. Mutat. Res. 93, 25-33.
56. Sniegowski P. D., Gerrish P. J. and Lenski R. E. 1997 Evolution of high mutation rates in experimental populations of E. coli. Nature 387, 703-705.
57. Stahl F. 1988 A unicorn in the garden. Nature 335, 112-113.
58. Taddei F., Radman M., Maynard Smith J., Toupance B., Gouyon P. H. and Godelle B. 1997a Role of mutators in adaptive evolution. Nature 387, 700-702.
59. Taddei F., Vulic M., Radman M. and Matic I. 1997b Genetic variability and adaptation to stress. In Environmental stress, adaptation, and evolution (ed. R. Bijlsma and V. Loeschcke), pp. 271-290. Birkhäuser, Basel.
60. Tenaillon O., Toupance B., Le Nagard H., Taddei F. and Godelle B. 1999 Mutators, population size, adaptive landscape, and the adaptation of asexual populations of bacteria. Genetics (in press).
61. Torkelson J., Harris R. S., Lombardo M.-J., Nagendran J., Thulin C. et al. 1997 Genome-wide hypermutation in a sub-population of stationary-phase cells underlies recombination-dependent adaptive mutation. EMBO J. 16, 3303-3311.
62. Treffers H. P., Spinelli V. and Belser N. O. 1954 A factor (or mutator gene) influencing mutation rates in E. coli. Proc. Natl. Acad. Sci USA 40, 1064-1071.
63. Tsui H.-C. T., Zhao G., Feng G., Leung H.-C. E. and Winkler M. E. 1994 The mutL repair gene of Escherichia coli K-12 forms a superoperon with a gene encoding a new cell-wall amidase. Mol. Microbiol. 11, 189-202.
64. Tsui H.-C. T., Feng G. and Winkler M. E. 1997 Negative regulation of mutS and mutH repair gene expression by the Hfq and RpoS global regulators of Escherichia coli K-12. J. Bacteriol. 179, 7476-7487.
65. Varlet I., Canard B., Brooks P., Cerovic G. and Radman M. 1996 Mismatch repair in Xenopus egg extracts: DNA strand breaks act as signals rather than excision points. Proc. Natl. Acad. Sci. USA 93, 10156-10161.
66. Vulic M., Dionisio F., Taddei F. and Radman M. 1997 Molecular keys to speciation: DNA polymorphism and the control of genetic exchange in enterobacteria. Proc. Natl. Acad. Sci. USA 94, 9763-9767.
67. Wu T.-H. and Marinus M. G. 1994 Dominant negative mutations in the mutS gene of Escherichia coli. J. Bacteriol. 176, 5393-5400.
68. Zamenhof P. J. 1966 A genetic locus responsible for generalized high mutability in Escherichia coli. Proc. Natl. Acad. Sci. USA 56, 845-852.