Novel pharmacokinetic measurement using electron paramagnetic resonance spectroscopy and simulation of in vivo decay of various nitroxyl spin probes in mouse blood

Journal of Pharmacology and Experimental Therapeutics

Volumn 310, Issue 3, 2004, Pages 1076-1083

  Matsumoto, Ken Ichiro ^a   Krishna, Murali C ^a,b   Mitchell, James B ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,2,6,6 TETRAMETHYLPIPERIDINE 1 OXYL; 3 CARBAMOYL 2,2,5,5 TETRAMETHYLPYRROLIDINE 1 OXYL; 4 OXO 2,2,6,6 TETRAMETHYLPIPERIDINE N OXYL; 4 TRIMETHYLAMMONIUM 2,2,6,6 TETRAMETHYLPIPERIDINE N OXYL; HYDROXYLAMINE; PIPERIDINE DERIVATIVE; PIPERIDINE NITROXYL DERIVATIVE; PYRROLIDINE DERIVATIVE; PYRROLIDINE NITROXYL; RADICAL; TEMPAMINE; TEMPOL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHEMICAL MODIFICATION; CIRCULATION; CONTROLLED STUDY; ELECTRON SPIN RESONANCE; FEMALE; IN VIVO STUDY; MOLECULAR PROBE; MOUSE; NONHUMAN; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; RADIATION PROTECTION; SPIN PROBE;

ANIMALS; ANTIOXIDANTS; COMPUTER SIMULATION; ELECTRON SPIN RESONANCE SPECTROSCOPY; INJECTIONS, INTRAVENOUS; MICE; NITROGEN OXIDES; SPIN LABELS; TIME FACTORS;

EID: 4243193691     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.104.066647     Document Type: Article

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