Toxicokinetic assessment of methylphenidate (Ritalin®) enantiomers in pregnant rats and rabbits

Biomedical Chromatography

Volumn 18, Issue 5, 2004, Pages 275-281

  Bakhtiar, Ray ^a,b   Tse, Francis L S ^a  

^a NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Atmospheric pressure chemical ionization; Enantioselective; Mass spectrometry; Methylphenidate; Ritalin ; Toxicokinetic; Vancomycin column

Indexed keywords

ATMOSPHERIC IONIZATION; ATMOSPHERIC PRESSURE; DRUG PRODUCTS; ENANTIOMERS; LIQUID CHROMATOGRAPHY; RATS; STEREOCHEMISTRY;

ATMOSPHERIC PRESSURE CHEMICAL IONIZATION; D-ISOMERS; ENANTIOSELECTIVE; METHYLPHENIDATE; PREGNANT RAT; RITALIN; RITALIN®; TOXICOKINETICS; VANCOMYCIN; VANCOMYCIN COLUMN;

MASS SPECTROMETRY;

METHYLPHENIDATE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATTENTION DEFICIT DISORDER; CONTROLLED STUDY; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG STRUCTURE; ENANTIOMER; FEMALE; LIQUID CHROMATOGRAPHY; MALE; NARCOLEPSY; NONHUMAN; PREGNANCY; PRESCRIPTION; RABBIT; RACEMIC MIXTURE; RAT; RAT STRAIN; STRUCTURE ANALYSIS; TANDEM MASS SPECTROMETRY; TOXICOKINETICS;

ORYCTOLAGUS CUNICULUS;

EID: 4243116487     PISSN: 02693879     EISSN: None     Source Type: Journal    
DOI: 10.1002/bmc.313     Document Type: Article

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