Corneal epithelial stem cells: Past, present, and future

Journal of Investigative Dermatology Symposium Proceedings

Volumn 9, Issue 3, 2004, Pages 202-207

  Sun, Tung Tien ^a   Lavker, Robert M ^b  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Limbal epithelium; Ocular surface disease; Transient amplifying cells; Wound repair

Indexed keywords

BIOLOGICAL MARKER; CELL MARKER;

BASEMENT MEMBRANE; CELL DIFFERENTIATION; CELL LABELING; CELLULAR DISTRIBUTION; CONFERENCE PAPER; CORNEA EPITHELIUM; EPITHELIUM CELL; IN VITRO STUDY; IN VIVO STUDY; LIMBIC CORTEX; NONHUMAN; PROTEIN EXPRESSION; SKIN CELL; STATISTICAL SIGNIFICANCE; STEM CELL; STEM CELL TRANSPLANTATION; TISSUE DIFFERENTIATION; TREATMENT INDICATION; WOUND HEALING;

EID: 4243073948     PISSN: 10870024     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1087-0024.2004.09311.x     Document Type: Conference Paper

References (65)

1. Anderson DE: Genetic study of eye cancer in cattle. J Hered 82:21-26, 1991
2. Bickenbach JR: Identification and behavior of label-retaining cells in oral mucosa and skin. J Dent Res 60:1611-1620, 1981
3. Bickenbach JR, Mackenzie BDS: Identification and behavior of label-retaining cells in hamster epithelia. J Invest Dermatol 82:618-622, 1984
4. Blau HM, Brazelton TR, Weimann JM: The evolving concept of a stem cell: Entity or function? Cell 105:829-841, 2001
5. Buck RC: Cell migration in repair of mouse corneal epithelium. Invest Opthalmol Vis Sci 18:767-784, 1979
6. Chen JJ, Tseng SC: Corneal epithelial wound healing in partial limbal deficiency. Invest Ophthalmol Vis Sci 31:1301-1314, 1990
7. Chen JJ, Tseng SC: Abnormal corneal epithelial wound healing in partial-thickness removal of limbal epithelium. Invest Ophthalmol Vis Sci 32:2219-2233, 1991
8. Chen T-T, Wu RL, Castro-Munozledo F, Sun T-T: Regulation of K3 keratin gene transcription by Sp1 and AP-2 in differentiating rabbit corneal epithelial cells. Mol Cell Biol 17:3056-3064, 1997
9. Chen WY, Mui MM, Kao WW, Lui CY, Tseng SC: Conjunctival epithelial cells do not transdifferentiate in organotypic cultures: Expression of K12 keratin is restricted to corneal epithelium. Curr Eye Res 13:765-768, 1994
10. Cotsarelis G, Cheng SZ, Dong G, Sun T-T, Lavker RM: Existence of slow-cycling limbal epithelial basal cells that can be preferentially stimulated to proliferate: Implications on epithelial stem cells. Cell 57:201-209, 1989
11. Davanger M, Evensen A: Role of the pericorneal papillary structure in renewal of corneal epithelium. Nature 229:560-561, 1971
12. Ebato B, Friend J, Thoft RA: Comparison of limbal and peripheral human corneal epithelium in tissue culture. Invest Ophthalmol Vis Sci 29:1533-1537, 1988
13. Espana EM, Di Pascuale M, Grueterich M, Solomon A, Tseng SCG: Keratolimbal allograft for corneal surface reconstruction. Eye 18:406-417, 2003
14. Ferraris C, Chevalier G, Favier B, Jahoda CA, Dhouailly D: Adult corneal epithelium basal cells possess the capacity to activate epidermal, pilosebaceous and sweat gland genetic programs in response to embryonic dermal stimuli. Development 127:5487-5495, 2000
15. Grueterich M, Espana EM, Tseng SCG: Ex vivo expansion of limbal stem cells: Amniotic membrane serving as a stem cell niche. Surv Ophthalmol 48:631-646, 2003
16. Holland E, Schwartz G: The evolution of epithelial transplantation for severe ocular surface disease and a proposed classification system. Cornea 15:549-556, 1996
17. Kenyon KR, Tseng SC: Limbal autograft transplantation for ocular surface disorders. Ophthalmology 96:709-722, 1989
18. Kim JC, Tseng SC: Transplantation of preserved human amniotic membrane for surface reconstruction in severely damaged rabbit corneas. Cornea 14:473-484, 1995
19. Koizumi N, Inatomi T, Suzuki T, Sotozono C, Kinoshita S: Cultivated corneal epithelial stem cell transplantation in ocular surface disorders. Ophthalmology 108:1569-1574, 2001
20. Kolega J, Manabe M, Sun TT: Basement membrane heterogeneity and variation in corneal epithelial differentiation. Differentiation 42:54-63, 1989
21. Kruse FE, Chen JJY, Tsai RJF, Tseng SCG: Conjunctival transdifferentiation is due to the incomplete removal of limbal basal epithelium. Invest Ophthalmol Vis Sci 31:1903-1913, 1990
22. Kruse FE, Volcker HE: Stem cells, wound healing, growth factors, and angiogenesis in the cornea. Curr Opin Ophthalmol 8:46-54, 1997
23. Kuwabara T, Perkins DG, Cogan DG: Sliding of the epithelium in experimental corneal wounds. Invest Opthalmol 15:4-14, 1976
24. Lavker RM, Sun T-T: Epidermal stem cells: Properties, markers, and location. Proc Nat Acad Sci USA 97:13473-13475, 2000
25. Lavker RM, Wei Z-G, Sun T-T: Phorbol ester preferentially stimulates mouse fornical conjunctival and limbal epithelial cells to proliferate in vivo. Invest Ophthalmol Vis Sci 39:101-107, 1998
26. Lehrer MS, Sun T-T, Lavker RM: Strategies of epithelial repair: Modulation of stem cell and transit amplifying cell proliferation. J Cell Sci 111:2867-2875, 1998
27. Lemp MA: What's new in ophthalmic surgery. J Am Coll Surg 195:361-363, 2002
28. Lindberg K, Brown ME, Chaves HV, Kenyan KR, Rheinwald JG: In vitro propagation of human ocular surface epithelial cells for transplantation. Invest Ophthalmol Vis Sci 34:2672-2679, 1993
29. Liu CY, Zhu G, Westerhausen LA, Converse R, Kao CW, Sun T-T, Kao WW: Cornea-specific expression of K12 keratin during mouse development. Curr Eye Res 12:963-974, 1993
30. Ljubimov AV, Burgeson RE, Betkowski RJ, Michael AF, Sun T-T, Kenney MC: Human corneal basement membrane heterogeneity: Topographical differences in the expression of type IV collagen and laminin isoforms. Lab Invest 72:461-473, 1995
31. Miller SJ, Lavker RM, Sun T-T: Keratinocyte stem cells of cornea, skin and hair follicle: Common and distinguishing features. Semin Dev Biol 4:217-240, 1993
32. Moll R, Franke WW, Schiller DL the catalog of human cytokeratins: Patterns of expression in normal epithelia, tumors and cultured cells. Cell 31:11-24, 1982
33. Morris RJ, Fischer SM, Slaga TJ: Evidence that the centrally and peripherally located cells in the murine epidermal proliferative unit are two distinct cell populations. J Invest Dermatol 84:277-281, 1985
34. Morrison SJ: Stem cell potential: Can anything make anything? Curr Biol 11:R7-R9, 2001
35. Moyer PD, Kaufman AH, Zhang Z, Kao CW, Spaulding AG, Kao WW: Conjunctival epithelial cells can resurface denuded cornea, but do not transdifferentiate to express cornea-specific keratin 12 following removal of limbal epithelium in mouse. Differentiation 60:31-38, 1996
36. Pellegrini G, Dellambra E, Golisano O, et al: p63 identifies keratinocyte stem cells. Proc Natl Acad Sci USA 98:3156-3161, 2001
37. Pellegrini G, Golisano O, Paterna P, Lambiase A, Bonini S, Rama P, DeLuca M: Location and clonal analysis of stem cells and their differentiated progeny in the human ocular surface. J Cell Biol 145:769-782, 1999
38. Pellegrini G, Traverso CE, Franzi AT, Zingirian M, Cancedda R, De Luca M: Long-term restoration of damaged corneal surfaces with autologous cultivated corneal epithelium. Lancet 349:990-993, 1997
39. Potten CS, Booth C: Keratinocyte stem cells: A commentary. J Invest Dermatol 119:888-899, 2002
40. Potten CS, Loeffler M: Stem cells: Attributes, cycles, spirals, pitfalls and uncertainties. Lessons for and from the crypt. Development 110:1001-1020, 1990
41. Reya T, Morrison SJ, Clarke MF, Weissman IL: Stem cells, cancer, and cancer stem cells. Nature 414:105-111, 2001
42. Schermer A, Galvin S, Sun T-T: Differentiation-related expression of a major 64K corneal keratin in vivo and in culture suggests limbal location of corneal epithelial stem cells. J Cell Biol 103:49-62, 1986
43. Schwab IR, Reyes M, Isseroff RR: Successful transplantation of bioengineered tissue replacements in patients with ocular surface disease. Cornea 19:421-426, 2000
44. Seaberg RM, van der Kooy D: Stem and progenitor cells: The premature desertion of rigorous definitions. Trends Neurosci 26:125-131, 2003
45. Srinivasan BD, Eakins KE: The reepithelialization of rabbit cornea following single and multiple denudation. Exp Eye Res 29:595-600, 1979
46. Sun L, Sun T-T, Lavker RM: Identification of a cytosolic NADP+-dependent isocitrate dehydrogenase that is preferentially expressed in bovine corneal epithelium: A corneal epithelial crystallin. J Biol Chem 274:17334-17341, 1999
47. Sun L, Sun T-T, Lavker RM: CLED: A calcium-linked protein associated with early epithelial differentiation. Exp Cell Res 259:96-106, 2000
48. Sun T-T, Eichner R, Schermer A, Cooper D, Nelson WG, Weiss RA: Classification, expression, and possible mechanisms of evolution of mammalian epithelial keratins: A unifying model. In: Levine A, Topp W, Woude G Vance, Watson JD (eds). Classification, Expression, and Possible Mechanisms of Evolution of Mammalian Epithelial Keratins: A Unifying Model. New York: Cold Spring Harbor, 1984; p 169-176
49. Tan DT, Ficker LA, Buckley RJ: Limbal transplantation. Ophthalmology 103:29-36, 1996
50. Tsai RJ, Li LM, Chen JK: Reconstruction of damaged corneas by transplantation of autologous limbal epithelial cells. N Engl J Med 343:86-93, 2000
51. Tsai RJ, Tseng SC: Human allograft limbal transplantation for corneal surface reconstruction. Cornea 13:389-400, 1994
52. Tseng SC: Significant impact of limbal epithelial stem cells. Int J Opthalmol 48:79-81, 2000
53. Tseng SC, Jarvinen MJ, Nelson WG, Huang JW, Woodcock-Mitchell J, Sun T-T: Correlation of specific keratins with different types of epithelial differentiation: Monoclonal antibody studies. Cell 30:361-372, 1982
54. Tseng SC, Prabhasawat P, Barton K, Gray T, Meller D: Amniotic membrane transplantation with or without limbal autografts for corneal surface reconstruction in patients with limbal stem cell deficiency. Arch Ophthalmol 116: 1998
55. Tseng SCG: Concept and application of limbal stem cells. Eye 3:141-157, 1989
56. Tsubota K: Corneal epithelial stem-cell transplantation. Lancet 349:990-993, 1997
57. Waring GO, Roth AM, Ekins MB: Clinical and pathologic description of 17 cases of corneal intraepithelial neoplasia. Am J Ophthalmol 97:547-559, 1984
58. Wei ZG, Cotsarelis G, Sun T-T, Lavker RM: Label-retaining cells are preferentially located in fornical epithelium: Implications on conjunctival epithelial homeostasis. Invest Ophthalmol Vis Sci 36:236-246, 1995
59. Wei ZG, Sun T-T, Lavker RM: Rabbit conjunctival and corneal epithelial cells belong to two separate lineages. Invest Ophthalmol Vis Sci 37:523-533, 1996
60. Wei ZG, Wu RL, Lavker RM, Sun T-T: In vitro growth and differentiation of rabbit bulbar, fornix, and palpebral conjunctival epithelia. Implications on conjunctival epithelial transdifferentiation and stem cells. Invest Ophthalmol Vis Sci 34:1814-1828, 1993
61. Wu RL, Chen T-T, Sun T-T: Functional importance of an Sp1- and an NFkB-related nuclear protein in a keratinocyte-specific promoter of rabbit K3 keratin gene. J Biol Chem 269:28450-28459, 1994
62. Wu RL, Galvin S, Wu SK, Xu C, Blumenberg M, Sun TT: A 300 bp 5′-upstream sequence of a differentiation-dependent rabbit K3 keratin gene can serve as a keratinocyte-specific promoter. J Cell Sci 105:303-316, 1993
63. Wu RL, Zhu G, Galvin S, et al: Lineage-specific and differentiation- dependent expression of K12 keratin in rabbit corneal/limbal epithelial cells: cDNA cloning and northern blot analysis. Differentiation 55:137-144, 1994
64. Zhu G, Ishizaki M, Haseba T, Wu RL, Sun T-T, Kao WW: Expression of K12 kertin in alkali-burned rabbit corneas. Curr Eye Res 11:875-887, 1994
65. Zieske JD, Bukusoglu G, Yankauckas MA, Wasson ME, Keutmann HT: Alpha-enolase is restricted to basal cells of stratified squamous epithelium. Dev Biol 151:18-26, 1992