-
1
-
-
0032433127
-
The central role of CD4(+) T cells in the antitumor immune response
-
Hung K, Hayashi R, Lafond-Walker A, Lowenstein C, Pardoll D, Levitsky H. The central role of CD4(+) T cells in the antitumor immune response. J Exp Med 1998;188:2357-68.
-
(1998)
J Exp Med
, vol.188
, pp. 2357-2368
-
-
Hung, K.1
Hayashi, R.2
Lafond-Walker, A.3
Lowenstein, C.4
Pardoll, D.5
Levitsky, H.6
-
2
-
-
0034541167
-
Tumor-specific CD4(+) T cells have a major "post-licensing" role in CTL mediated anti-tumor immunity
-
Marzo AL, Kinnear BF, Lake RA, et al. Tumor-specific CD4(+) T cells have a major "post-licensing" role in CTL mediated anti-tumor immunity. J Immunol 2000;165:6047-55.
-
(2000)
J Immunol
, vol.165
, pp. 6047-6055
-
-
Marzo, A.L.1
Kinnear, B.F.2
Lake, R.A.3
-
3
-
-
23244447692
-
Phenotype and homing of CD4 tumor-specific T cells is modulated by tumor bulk
-
Benigni F, Zimmermann VS, Hugues S, et al. Phenotype and homing of CD4 tumor-specific T cells is modulated by tumor bulk. J Immunol 2005;175:739-48.
-
(2005)
J Immunol
, vol.175
, pp. 739-748
-
-
Benigni, F.1
Zimmermann, V.S.2
Hugues, S.3
-
4
-
-
0029979997
-
Melanoma-specific CD4+ T cells recognize nonmutated HLA-DR-restricted tyrosinase epitopes
-
Topalian SL, Gonzales MI, Parkhurst M, et al. Melanoma-specific CD4+ T cells recognize nonmutated HLA-DR-restricted tyrosinase epitopes. J Exp Med 1996;183:1965-71.
-
(1996)
J Exp Med
, vol.183
, pp. 1965-1971
-
-
Topalian, S.L.1
Gonzales, M.I.2
Parkhurst, M.3
-
5
-
-
0033103192
-
Melanoma cells present a MAGE-3 epitope to CD4(+) cytotoxic T cells in association with histocompatibility leukocyte antigen DR11 [see comments]
-
Manici S, Sturniolo T, Imro MA, et al. Melanoma cells present a MAGE-3 epitope to CD4(+) cytotoxic T cells in association with histocompatibility leukocyte antigen DR11 [see comments]. J Exp Med 1999;189:871-6.
-
(1999)
J Exp Med
, vol.189
, pp. 871-876
-
-
Manici, S.1
Sturniolo, T.2
Imro, M.A.3
-
6
-
-
0033103147
-
Biochemical identification of a mutated human melanoma antigen recognized by CD4(+) T cells [see comments]
-
Pieper R, Christian RE, Gonzales MI, et al. Biochemical identification of a mutated human melanoma antigen recognized by CD4(+) T cells [see comments]. J Exp Med 1999;189:757-66.
-
(1999)
J Exp Med
, vol.189
, pp. 757-766
-
-
Pieper, R.1
Christian, R.E.2
Gonzales, M.I.3
-
7
-
-
33645787216
-
Identification of novel subdominant epitopes on the carcinoembryonic antigen recognized by CD4+ T cells of lung cancer patients
-
Crosti M, Longhi R, Consogno G, Melloni G, Zannini P, Protti MP. Identification of novel subdominant epitopes on the carcinoembryonic antigen recognized by CD4+ T cells of lung cancer patients. J Immunol 2006;176:5093-9.
-
(2006)
J Immunol
, vol.176
, pp. 5093-5099
-
-
Crosti, M.1
Longhi, R.2
Consogno, G.3
Melloni, G.4
Zannini, P.5
Protti, M.P.6
-
8
-
-
0032477815
-
Induction of antigen-specific T cell anergy: An early event in the course of tumor progression
-
Staveley-O'Carroll K, Sotomayor E, Montgomery J, et al. Induction of antigen-specific T cell anergy: an early event in the course of tumor progression. Proc Natl Acad Sci U S A 1998;95:1178-83.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 1178-1183
-
-
Staveley-O'Carroll, K.1
Sotomayor, E.2
Montgomery, J.3
-
9
-
-
0032984347
-
Conversion of tumor-specific CD4+ T-cell tolerance to T-cell priming through in vivo ligation of CD40
-
Sotomayor EM, Borrello I, Tubb E, et al. Conversion of tumor-specific CD4+ T-cell tolerance to T-cell priming through in vivo ligation of CD40. Nat Med 1999;5:780-7.
-
(1999)
Nat Med
, vol.5
, pp. 780-787
-
-
Sotomayor, E.M.1
Borrello, I.2
Tubb, E.3
-
10
-
-
38449094324
-
Tumors hamper the immunogenic competence of CD4+ T cell-directed dendritic cell vaccination
-
Zimmermann VS, Casati A, Schiering C, et al. Tumors hamper the immunogenic competence of CD4+ T cell-directed dendritic cell vaccination. J Immunol 2007;179:2899-909.
-
(2007)
J Immunol
, vol.179
, pp. 2899-2909
-
-
Zimmermann, V.S.1
Casati, A.2
Schiering, C.3
-
11
-
-
0031941423
-
Vaccination of melanoma patients with peptide- or tumor lysatepulsed dendritic cells
-
Nestle FO, Alijagic S, Gilliet M, et al. Vaccination of melanoma patients with peptide- or tumor lysatepulsed dendritic cells. Nat Med 1998;4:328-32.
-
(1998)
Nat Med
, vol.4
, pp. 328-332
-
-
Nestle, F.O.1
Alijagic, S.2
Gilliet, M.3
-
12
-
-
1642577047
-
Functional analysis of tumor-specific Th cell responses detected in melanoma patients after dendritic cell-based immunotherapy
-
Schultz ES, Schuler-Thurner B, Stroobant V, et al. Functional analysis of tumor-specific Th cell responses detected in melanoma patients after dendritic cell-based immunotherapy. J Immunol 2004;172:1304-10.
-
(2004)
J Immunol
, vol.172
, pp. 1304-1310
-
-
Schultz, E.S.1
Schuler-Thurner, B.2
Stroobant, V.3
-
13
-
-
0032473562
-
Specific T helper cell requirement for optimal induction of cytotoxic T lymphocytes against major histocompatibility complex class II negative tumors
-
Ossendorp F, Mengede E, Camps M, Filius R, Melief CJ. Specific T helper cell requirement for optimal induction of cytotoxic T lymphocytes against major histocompatibility complex class II negative tumors. J Exp Med 1998;187:693-702.
-
(1998)
J Exp Med
, vol.187
, pp. 693-702
-
-
Ossendorp, F.1
Mengede, E.2
Camps, M.3
Filius, R.4
Melief, C.J.5
-
14
-
-
0034975140
-
Immunization with a tumor-associated CTL epitope plus a tumor-related or unrelated Th1 helper peptide elicits protective CTL immunity
-
Casares N, Lasarte JJ, de Cerio AL, et al. Immunization with a tumor-associated CTL epitope plus a tumor-related or unrelated Th1 helper peptide elicits protective CTL immunity. Eur J Immunol 2001;31:1780-9.
-
(2001)
Eur J Immunol
, vol.31
, pp. 1780-1789
-
-
Casares, N.1
Lasarte, J.J.2
de Cerio, A.L.3
-
15
-
-
0029078151
-
Immunization with a single T helper cell epitope abrogates Friend virus-induced early erythroid proliferation and prevents late leukemia development
-
Miyazawa M, Fujisawa R, Ishihara C, et al. Immunization with a single T helper cell epitope abrogates Friend virus-induced early erythroid proliferation and prevents late leukemia development. J Immunol 1995;155:748-58.
-
(1995)
J Immunol
, vol.155
, pp. 748-758
-
-
Miyazawa, M.1
Fujisawa, R.2
Ishihara, C.3
-
16
-
-
1642352727
-
CD4-directed peptide vaccination augments an antitumor response, but efficacy is limited by the number of CD8+ T cell precursors
-
Hanson HL, Kang SS, Norian LA, Matsui K, O'Mara LA, Allen PM. CD4-directed peptide vaccination augments an antitumor response, but efficacy is limited by the number of CD8+ T cell precursors. J Immunol 2004;172:4215-24.
-
(2004)
J Immunol
, vol.172
, pp. 4215-4224
-
-
Hanson, H.L.1
Kang, S.S.2
Norian, L.A.3
Matsui, K.4
O'Mara, L.A.5
Allen, P.M.6
-
17
-
-
17144417748
-
Dendritic cells as therapeutic vaccines against cancer
-
Banchereau J, Palucka AK, Dendritic cells as therapeutic vaccines against cancer. Nat Rev Immunol 2005;5:296-306.
-
(2005)
Nat Rev Immunol
, vol.5
, pp. 296-306
-
-
Banchereau, J.1
Palucka, A.K.2
-
18
-
-
34247212403
-
Engineering artificial antigen-presenting cells to express a diverse array of co-stimulatory molecules
-
Suhoski MM, Golovina TN, Aqui NA, et al. Engineering artificial antigen-presenting cells to express a diverse array of co-stimulatory molecules. Mol Ther 2007;15:981-8.
-
(2007)
Mol Ther
, vol.15
, pp. 981-988
-
-
Suhoski, M.M.1
Golovina, T.N.2
Aqui, N.A.3
-
19
-
-
0037377321
-
T cell stimulation and expansion using anti-CD3/CD28 beads
-
Trickett A, Kwan YL. T cell stimulation and expansion using anti-CD3/CD28 beads. J Immunol Methods 2003;275:251-5.
-
(2003)
J Immunol Methods
, vol.275
, pp. 251-255
-
-
Trickett, A.1
Kwan, Y.L.2
-
20
-
-
0031563897
-
Artificial cell surface constructs for studying receptor-ligand contributions to lymphocyte activation
-
Curtsinger J, Deeths MJ, Pease P, Mescher MF. Artificial cell surface constructs for studying receptor-ligand contributions to lymphocyte activation. J Immunol Methods 1997;209:47-57.
-
(1997)
J Immunol Methods
, vol.209
, pp. 47-57
-
-
Curtsinger, J.1
Deeths, M.J.2
Pease, P.3
Mescher, M.F.4
-
21
-
-
0035283051
-
Activation of antigen-specific T cells by artificial cell constructs having immobilized multimeric peptide-class I complexes and recombinant B7-Fc proteins
-
Tham EL, Jensen PL, Mescher MF. Activation of antigen-specific T cells by artificial cell constructs having immobilized multimeric peptide-class I complexes and recombinant B7-Fc proteins. J Immunol Methods 2001;249:111-9.
-
(2001)
J Immunol Methods
, vol.249
, pp. 111-119
-
-
Tham, E.L.1
Jensen, P.L.2
Mescher, M.F.3
-
22
-
-
1642576146
-
Phase I trial of large multivalent immunogen derived from melanoma lysates in patients with disseminated melanoma
-
Mitchell MS, Kan-Mitchell J, Morrow PR, Darrah D, Jones VE, Mescher MF. Phase I trial of large multivalent immunogen derived from melanoma lysates in patients with disseminated melanoma. Clin Cancer Res 2004;10:76-83.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 76-83
-
-
Mitchell, M.S.1
Kan-Mitchell, J.2
Morrow, P.R.3
Darrah, D.4
Jones, V.E.5
Mescher, M.F.6
-
23
-
-
0038587735
-
Ex vivo induction and expansion of antigen-specific cytotoxic T cells by HLA-Ig-coated artificial antigen-presenting cells
-
Oelke M, Maus MV, Didiano D, June CH, Mackensen A, Schneck JP. Ex vivo induction and expansion of antigen-specific cytotoxic T cells by HLA-Ig-coated artificial antigen-presenting cells. Nat Med 2003;9:619-24.
-
(2003)
Nat Med
, vol.9
, pp. 619-624
-
-
Oelke, M.1
Maus, M.V.2
Didiano, D.3
June, C.H.4
Mackensen, A.5
Schneck, J.P.6
-
24
-
-
0037288512
-
HLA tetramer-based artificial antigen-presenting cells for stimulation of CD4+ T cells
-
Maus MV, Riley JL, Kwok WW, Nepom GT, June CH. HLA tetramer-based artificial antigen-presenting cells for stimulation of CD4+ T cells. Clin Immunol 2003;106:16-22.
-
(2003)
Clin Immunol
, vol.106
, pp. 16-22
-
-
Maus, M.V.1
Riley, J.L.2
Kwok, W.W.3
Nepom, G.T.4
June, C.H.5
-
25
-
-
0033012235
-
Liposomes with incorporated MHC class II/peptide complexes as antigen presenting vesicles for specific T cell activation
-
van Rensen AJ, Wauben MH, Grosfeld-Stulemeyer MC, van Eden W, Crommelin DJ. Liposomes with incorporated MHC class II/peptide complexes as antigen presenting vesicles for specific T cell activation. Pharm Res 1999;16:198-204.
-
(1999)
Pharm Res
, vol.16
, pp. 198-204
-
-
van Rensen, A.J.1
Wauben, M.H.2
Grosfeld-Stulemeyer, M.C.3
van Eden, W.4
Crommelin, D.J.5
-
26
-
-
0034536760
-
Artificial antigen-presenting cells as a tool to exploit the immune 'synapse'
-
Prakken B, Wauben M, Genini D, et al. Artificial antigen-presenting cells as a tool to exploit the immune 'synapse'. Nat Med 2000;6:1406-10.
-
(2000)
Nat Med
, vol.6
, pp. 1406-1410
-
-
Prakken, B.1
Wauben, M.2
Genini, D.3
-
27
-
-
0026708528
-
Augmentation of in vivo cytotoxic T lymphocyte activity and reduction of tumor growth by large multivalent immunogen
-
Rogers J, Mescher MF. Augmentation of in vivo cytotoxic T lymphocyte activity and reduction of tumor growth by large multivalent immunogen. J Immunol 1992;149:269-76.
-
(1992)
J Immunol
, vol.149
, pp. 269-276
-
-
Rogers, J.1
Mescher, M.F.2
-
28
-
-
0031172792
-
Stimulation of tumor-specific immunity using tumor cell plasma membrane antigen
-
Mescher MF, Savelieva E. Stimulation of tumor-specific immunity using tumor cell plasma membrane antigen. Methods 1997;12:155-64.
-
(1997)
Methods
, vol.12
, pp. 155-164
-
-
Mescher, M.F.1
Savelieva, E.2
-
29
-
-
0037220792
-
In vivo augmentation of tumor-specific CTL responses by class I/peptide antigen complexes on microspheres (large multivalent immunogen)
-
Goldberg J, Shrikant P, Mescher MF. In vivo augmentation of tumor-specific CTL responses by class I/peptide antigen complexes on microspheres (large multivalent immunogen). J Immunol 2003;170:228-35.
-
(2003)
J Immunol
, vol.170
, pp. 228-235
-
-
Goldberg, J.1
Shrikant, P.2
Mescher, M.F.3
-
30
-
-
2442714006
-
Extensive replicative capacity of human central memory T cells
-
Maus MV, Kovacs B, Kwok WW, et al. Extensive replicative capacity of human central memory T cells. J Immunol 2004;172:6675-83.
-
(2004)
J Immunol
, vol.172
, pp. 6675-6683
-
-
Maus, M.V.1
Kovacs, B.2
Kwok, W.W.3
-
31
-
-
0034502179
-
Selective activation and expansion of high-affinity CD4+ T cells in resistant mice upon infection with Leishmania major
-
Malherbe L, Filippi C, Julia V, et al. Selective activation and expansion of high-affinity CD4+ T cells in resistant mice upon infection with Leishmania major. Immunity 2000;13:771-82.
-
(2000)
Immunity
, vol.13
, pp. 771-782
-
-
Malherbe, L.1
Filippi, C.2
Julia, V.3
-
32
-
-
0025697469
-
Induction by antigen of intrathymic apoptosis of CD4+CD8+TCRlo thymocytes in vivo
-
Murphy KM, Heimberger AB, Loh DY. Induction by antigen of intrathymic apoptosis of CD4+CD8+TCRlo thymocytes in vivo. Science 1990;250:1720-3.
-
(1990)
Science
, vol.250
, pp. 1720-1723
-
-
Murphy, K.M.1
Heimberger, A.B.2
Loh, D.Y.3
-
33
-
-
0038079749
-
Critical impact of the kinetics of dendritic cells activation on the in vivo induction of tumor-specific T lymphocytes
-
Camporeale A, Boni A, Iezzi G, et al. Critical impact of the kinetics of dendritic cells activation on the in vivo induction of tumor-specific T lymphocytes. Cancer Res 2003;63:3688-94.
-
(2003)
Cancer Res
, vol.63
, pp. 3688-3694
-
-
Camporeale, A.1
Boni, A.2
Iezzi, G.3
-
34
-
-
0027421675
-
Normal sequence of phenotypic transitions in one cohort of 5-bromo-2′-deoxyuridine-pulse-labeled thymocytes. Correlation with T cell receptor expression
-
Lucas B, Vasseur F, Penit C. Normal sequence of phenotypic transitions in one cohort of 5-bromo-2′-deoxyuridine-pulse-labeled thymocytes. Correlation with T cell receptor expression. J Immunol 1993;151:4574-82.
-
(1993)
J Immunol
, vol.151
, pp. 4574-4582
-
-
Lucas, B.1
Vasseur, F.2
Penit, C.3
-
35
-
-
0028262128
-
Determination of lymphocyte division by flow cytometry
-
Lyons AB, Parish CR. Determination of lymphocyte division by flow cytometry. J Immunol Methods 1994;171:131-7.
-
(1994)
J Immunol Methods
, vol.171
, pp. 131-137
-
-
Lyons, A.B.1
Parish, C.R.2
-
36
-
-
14644444117
-
IL-7: Maintaining T-cell memory and achieving homeostasis
-
Bradley LM, Haynes L, Swain SL. IL-7: maintaining T-cell memory and achieving homeostasis. Trends Immunol 2005;26:172-6.
-
(2005)
Trends Immunol
, vol.26
, pp. 172-176
-
-
Bradley, L.M.1
Haynes, L.2
Swain, S.L.3
-
37
-
-
22144437688
-
Central memory self/tumor-reactive CD8+ T cells confer superior antitumor immunity compared with effector memory T cells
-
Klebanoff CA, Gattinoni L, Torabi-Parizi P, et al. Central memory self/tumor-reactive CD8+ T cells confer superior antitumor immunity compared with effector memory T cells. Proc Natl Acad Sci U S A 2005;102:9571-6.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 9571-9576
-
-
Klebanoff, C.A.1
Gattinoni, L.2
Torabi-Parizi, P.3
-
38
-
-
20444499355
-
Acquisition of full effector function in vitro paradoxically impairs the in vivo antitumor efficacy of adoptively transferred CD8(+) T cells
-
Gattinoni L, Klebanoff CA, Palmer DC, et al. Acquisition of full effector function in vitro paradoxically impairs the in vivo antitumor efficacy of adoptively transferred CD8(+) T cells. J Clin Invest 2005;115:1616-26.
-
(2005)
J Clin Invest
, vol.115
, pp. 1616-1626
-
-
Gattinoni, L.1
Klebanoff, C.A.2
Palmer, D.C.3
-
39
-
-
11844306664
-
Functional heterogeneity of memory CD4 T-cell responses in different conditions of antigen exposure and persistence
-
Harari A, Vallelian F, Meylan PR, Pantaleo G. Functional heterogeneity of memory CD4 T-cell responses in different conditions of antigen exposure and persistence. J Immunol 2005;174:1037-45.
-
(2005)
J Immunol
, vol.174
, pp. 1037-1045
-
-
Harari, A.1
Vallelian, F.2
Meylan, P.R.3
Pantaleo, G.4
-
40
-
-
15744397592
-
Immune surveillance and anti-tumor immune responses: An anatomical perspective
-
Zimmermann VS, Benigni F, Mondino A. Immune surveillance and anti-tumor immune responses: an anatomical perspective. Immunol Lett 2005;98:1-8.
-
(2005)
Immunol Lett
, vol.98
, pp. 1-8
-
-
Zimmermann, V.S.1
Benigni, F.2
Mondino, A.3
-
41
-
-
34548138945
-
Identification of T-cell epitopes for cancer immunotherapy
-
Kessler JH, Melief CJ. Identification of T-cell epitopes for cancer immunotherapy. Leukemia 2007;21:1859-74.
-
(2007)
Leukemia
, vol.21
, pp. 1859-1874
-
-
Kessler, J.H.1
Melief, C.J.2
-
42
-
-
1642504308
-
MHC Class II tetramers and the pursuit of antigen-specific T cells: Define, deviate, delete
-
Mallone R, Nepom GT. MHC Class II tetramers and the pursuit of antigen-specific T cells: define, deviate, delete. Clin Immunol 2004;110:232-42.
-
(2004)
Clin Immunol
, vol.110
, pp. 232-242
-
-
Mallone, R.1
Nepom, G.T.2
-
43
-
-
36348961303
-
Potent costimulation of human CD8 T cells by anti-4-1BB and anti-CD28 on synthetic artificial antigen presenting cells
-
Rudolf D, Silberzahn T, Walter S, et al. Potent costimulation of human CD8 T cells by anti-4-1BB and anti-CD28 on synthetic artificial antigen presenting cells. Cancer Immunol Immunother 2007;53:175-83.
-
(2007)
Cancer Immunol Immunother
, vol.53
, pp. 175-183
-
-
Rudolf, D.1
Silberzahn, T.2
Walter, S.3
-
44
-
-
42349097028
-
4-1BB is superior to CD28 costimulation for generating CD8+ cytotoxic lymphocytes for adoptive immunotherapy
-
Zhang H, Snyder KM, Suhoski MM, et al. 4-1BB is superior to CD28 costimulation for generating CD8+ cytotoxic lymphocytes for adoptive immunotherapy. J Immunol 2007;179:4910-8.
-
(2007)
J Immunol
, vol.179
, pp. 4910-4918
-
-
Zhang, H.1
Snyder, K.M.2
Suhoski, M.M.3
-
45
-
-
10744233636
-
Blockade of T-cell activation using a surface-linked single-chain antibody to CTLA-4 (CD152)
-
Griffin MD, Hong DK, Holman PO, et al. Blockade of T-cell activation using a surface-linked single-chain antibody to CTLA-4 (CD152). J Immunol 2000;164:4433-42.
-
(2000)
J Immunol
, vol.164
, pp. 4433-4442
-
-
Griffin, M.D.1
Hong, D.K.2
Holman, P.O.3
|