Sensing tension: Epithelial sodium channel/acid-sensing ion channel proteins in cardiovascular homeostasis

Hypertension

Volumn 51, Issue 5, 2008, Pages 1265-1271

  Drummond, Heather A ^a   Jernigan, Nikki L ^b   Grifoni, Samira C ^a  

^a UNIVERSITY OF MISSISSIPPI SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NEW MEXICO SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALDOSTERONE; AMILORIDE; BENZAMIL; EPITHELIAL SODIUM CHANNEL; EPLERENONE; SEMATILIDE; SPIRONOLACTONE;

BLOOD PRESSURE REGULATION; CAENORHABDITIS ELEGANS; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; DROSOPHILA; DRUG INHIBITION; HEART PROTECTION; HOMEOSTASIS; HUMAN; HYPERTENSION; HYPOTENSION; MECHANORECEPTOR; MECHANOTRANSDUCTION; NONHUMAN; ORGAN INJURY; PRESSORECEPTOR; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INTERACTION; RANDOMIZED CONTROLLED TRIAL; REVIEW; SALT LOSING NEPHRITIS; VASCULAR RESISTANCE; VASOCONSTRICTION; WATER TRANSPORT; XENOPUS;

ANIMALS; CARDIOVASCULAR DISEASES; CARDIOVASCULAR PHYSIOLOGY; EPITHELIAL SODIUM CHANNEL; HOMEOSTASIS; HUMANS; MECHANOTRANSDUCTION, CELLULAR; MEMBRANE PROTEINS; NERVE TISSUE PROTEINS; SODIUM CHANNELS;

EID: 42349100626     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.107.093401     Document Type: Review

References (58)

1. Kellenberger S, Schild L. Epithelial sodium channel/degenerin family of ion channels: a variety of functions for a shared structure. Physiol Rev. 2002;82:735-767.
2. Syntichaki P, Tavernarakis N. Genetic models of mechanotransduction: the nematode Caenorhabditis elegans. Physiol Rev. 2004;84:1097-1153.
3. Ji HL, Su XF, Kedar S, Li J, Barbry P, Smith PR, Matalon S, Benos DJ. Delta-subunit confers novel biophysical features to alpha beta gamma-human epithelial sodium channel (ENaC) via a physical interaction. J Biol Chem. 2006;281:8233-8241.
4. Waldmann R, Champigny G, Bassilana F, Voilley N, Lazdunski M. Molecular cloning and functional expression of a novel amiloride- sensitive Na+ channel. J Biol Chem. 1995;270:27411-27414.
5. Brockway LM, Zhou ZH, Bubien JK, Jovov B, Benos DJ, Keyser KT. Rabbit retinal neurons and glia express a variety of ENaC/DEG subunits. Am J Physiol Cell Physiol. 2002;283:C126-C134.
6. Babini E, Geisler HS, Siba M, Grunder S. A new subunit of the epithelial Na+ channel identifies regions involved in Na+ self-inhibition. J Biol Chem. 2003;278:28418-28426.
7. Bonny O, Chraibi A, Loffing J, Jaeger NF, Grunder S, Horisberger JD, Rossier BC. Functional expression of a pseudohypoaldosteronism type I mutated epithelial Na+ channel lacking the pore-forming region of its alpha subunit. J Clin Invest. 1999;104:967-974.
8. Grifoni SC, Jernigan NL, Hamilton G, Drummond HA. ASIC proteins regulate smooth muscle cell migration. Microvasc Res. 2008;75:202-210.
9. Awayda MS, Ismailov II, Berdiev BK, Benos DJ. A cloned renal epithelial Na+ channel protein displays stretch activation in planar lipid bilayers. Am J Physiol. 1995;268:C1450-C1459.
10. Kizer N, Guo X-L, Hruska K. Reconstitution of stretch-activated cation channels by expression of the α-subunit of the epithelial sodium channel cloned from osteoblasts. Proc Natl Acad Sci U S A. 1997;94:1013-1018.
11. Palmer LG, Frindt G. Gating of Na channels in the rat cortical collecting tubule: effects of voltage and membrane stretch. J Gen Physiol. 1996;107:35-45.
12. Ma HP, Li L, Zhou ZH, Eaton DC, Warnock DG. ATP masks stretch activation of epithelial sodium channels in A6 distal nephron cells. Am J Physiol Renal Physiol. 2002;282:F501-F505.
13. Awayda MS, Subramanyam M. Regulation of the epithelial Na+ channel by membrane tension. J Gen Physiol. 1998;112:97-111.
14. Ji H-L, Fuller CM, Benos DJ. Osmotic pressure regulates αβγ-rENaC expressed in Xenopus oocytes. Am J Physiology. 1998;275:C1182-C1190.
15. Carattino MD, Sheng S, Kleyman TR. Epithelial Na+ channels are activated by laminar shear stress. J Biol Chem. 2004;279:4120-4126.
16. Satlin LM, Sheng S, Woda CB, Kleyman TR. Epithelial Na(+) channels are regulated by flow. Am J Physiol Renal Physiol. 2001;280:F1010-F1018.
17. Waldmann R, Champigny G, Lingueglia E, De Weille JR, Heurteaux C, Lazdunski M. H(+)-gated cation channels. Ann N Y Acad Sci. 1999;868:67-76.
18. Barker PM, Nguyen MS, Gatzy JT, Grubb B, Norman H, Hummler E, Rossier B, Boucher RC, Koller B. Role of gammaENaC subunit in lung liquid clearance and electrolyte balance in newborn mice. Insights into perinatal adaptation and pseudohypoaldosteronism. J Clin Invest. 1998;102:1634-1640.
19. Hummler E, Barker P, Gatzy J, Beermann F, Verdumo C, Schmidt A, Boucher R, Rossier BC. Early death due to defective neonatal lung liquid clearance in alpha- ENaC-deficient mice. Nat Genet. 1996;12:325-328.
20. McDonald FJ, Yang B, Hrstka RF, Drummond HA, Tarr DE, McCray PB Jr, Stokes JB, Welsh MJ, Williamson RA. Disruption of the beta subunit of the epithelial Na+ channel in mice: hyperkalemia and neonatal death associated with a pseudohypoaldosteronism phenotype. Proc Natl Acad Sci U S A. 1999;96:1727-1731.
21. Kleyman TR, Cragoe EJ Jr. Amiloride and its analogs as tools in the study of ion transport. J Membr Biol. 1988;105:1-21.
22. Drummond HA, Price MP, Welsh MJ, Abboud FM. A molecular component of the arterial baroreceptor mechanotransducer. Neuron. 1998;21:1435-1441.
23. Drummond HA, Abboud FM, Welsh MJ. Localization of beta and gamma subunits of ENaC in sensory nerve endings in the rat foot pad. Brain Res. 2000;884:1-12.
24. Fricke B, Lints R, Stewart G, Drummond H, Dodt G, Driscoll M, von During M. Epithelial Na+ channels and stomatin are expressed in rat trigeminal mechanosensory neurons. Cell Tissue Res. 2000;299:327-334.
25. Molliver DC, Immke DC, Fierro L, Pare M, Rice FL, McCleskey EW. ASIC3, an acid-sensing ion channel, is expressed in metaboreceptive sensory neurons. Mol Pain. 2005;1:35.
26. Lu Y, Whiteis CA, Benson CJ, Chapleau MW, Abboud FM. Expression and localization of acid-sensing ion channels in mouse nodose ganglia. FASEB J. 2006;20:A775.
27. Snitsarev V, Whiteis CA, Abboud FM, Chapleau MW. Mechanosensory transduction of vagal and baroreceptor afferents revealed by study of isolated nodose neurons in culture. Auton Neurosci. 2002;98:59-63.
28. Sabharwal R, Stauss HM, Lazartigues E, Whiteis CA, Davisson RL, Price MP, Welsh MJ, Abboud FM, Chapleau MW. Abnormalities in baroreflex sensitivity and autonomic control in conscious ASIC2-/- mice. FASEB J. 2006;20:A1186.
29. Bidani AK, Griffin KA. Pathophysiology of hypertensive renal damage: implications for therapy. Hypertension. 2004;44:595-601.
30. Smeda JS, Payne GW. Alterations in autoregulatory and myogenic function in the cerebrovasculature of Dahl salt-sensitive rats. Stroke. 2003;34:1484-1490.
31. Drummond HA, Gebremedhin D, Harder DR. Degenerin/epithelial Na+ channel proteins: components of a vascular mechanosensor. Hypertension. 2004;44:643-648.
32. Jernigan NL, Drummond HA. Vascular ENaC proteins are required for renal myogenic constriction. Am J Physiol Renal Physiol. 2005;289:F891-F901.
33. Jernigan NL, Drummond HA. Myogenic vasoconstriction in mouse renal interlobar arteries: role of endogenous beta and gammaENaC. Am J Physiol Renal Physiol. 2006;291:F1184-F1191.
34. Gannon KP, Galmiche L, Drummond HA. ASIC2 protein is required for pressure-induced constriction in mouse middle cerebral artery. Am J Physiol Heart Circ Physiol. 2008;Feb 22 [Epub ahead of print].
35. Oyabe A, Masumoto N, Ueta K, Nakayama K. Amiloride-sensitive pressure-induced myogenic contraction in rat cerebral artery. Fundam Clin Pharmacol. 2000;14:369-377.
36. Guan ZCA, Inscho E. Effect of ENaC blockade on the myogenic response of rat juxtamedullary afferent arterioles. FASEB J. 2007;21:595.15. Abstract.
37. Meltzer RH, Kapoor N, Qadri YJ, Anderson SJ, Fuller CM, Benos DJ. Heteromeric assembly of acid-sensitive ion channel and epithelial sodium channel subunits. J Biol Chem. 2007;282:25548-25559.
38. Berdiev BK, Xia J, McLean LA, Markert JM, Gillespie GY, Mapstone TB, Naren AP, Jovov B, Bubien JK, Ji HL, Fuller CM, Kirk KL, Benos DJ. Acid-sensing ion channels in malignant gliomas. J Biol Chem. 2003;278:15023-15034.
39. Van Renterghem C, Lazdunski M. A new non-voltage-dependent, epithelial-like Na+ channel in vascular smooth muscle cells. Pflugers Arch. 1991;419:401-408.
40. Hughey RP, Bruns JB, Kinlough CL, Harkleroad KL, Tong Q, Carattino MD, Johnson JP, Stockand JD, Kleyman TR. Epithelial sodium channels are activated by furin-dependent proteolysis. J Biol Chem. 2004;279:18111-18114.
41. Caldwell RA, Boucher RC, Stutts MJ. Serine protease activation of near-silent epithelial Na+ channels. Am J Physiol Cell Physiol. 2004;286:C190-C194.
42. Tan ZY, Lu Y, Whiteis CA, Benson CJ, Chapleau MW, Abboud FM. Acid-sensing ion channels contribute to transduction of extracellular acidosis in rat carotid body glomus cells. Circ Res. 2007;101:1009-1019.
43. Sabharwal R, Chapleau MW, Price MP, Welsh MJ, Abboud FM. Molecular mechanisms of baro- and chemoreceptor activation: evidence that ASIC1 and ASIC3 contribute to chemoreceptor activation. Hypertension. 2005;46:832. Abstract.
44. Benson CJ, Eckert SP, McCleskey EW. Acid-evoked currents in cardiac sensory neurons: a possible mediator of myocardial ischemic sensation. Circ Res. 1999;84:921-928.
45. Sutherland SP, Benson CJ, Adelman JP, McCleskey EW. Acid-sensing ion channel 3 matches the acid-gated current in cardiac ischemia-sensing neurons. Proc Natl Acad Sci U S A. 2001;98:711-716.
46. Li J, Maile MD, Sinoway AN, Sinoway LI. Muscle pressor reflex: potential role of vanilloid type 1 receptor and acid-sensing ion channel. J Appl Physiol. 2004;97:1709-1714.
47. Hayes SG, Kindig AE, Kaufman MP. Blockade of acid sensing ion channels attenuates the exercise pressor reflex in cats. J Physiol. 2007;581:1271-1282.
48. Guyton AC, Hall JE. Textbook of Medical Physiology. 11th ed. Philadelphia, PA: Elsevier Saunders; 2006.
49. Immke DC, McCleskey EW. Lactate enhances the acid-sensing Na+ channel on ischemia-sensing neurons. Nat Neurosci. 2001;4:869-870.
50. Sluka KA, Price MP, Breese NM, Stucky CL, Wemmie JA, Welsh MJ. Chronic hyperalgesia induced by repeated acid injections in muscle is abolished by the loss of ASIC3, but not ASIC1. Pain. 2003;106:229-239.
51. Clapham DE, Runnels LW, Strubing C. The TRP ion channel family. Nat Rev Neurosci. 2001;2:387-396.
52. Pitt B, Zannad F, Remme WJ, Cody R, Castaigne A, Perez A, Palensky J, Wittes J. The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators. N Engl J Med. 1999;341:709-717.
53. Pitt B, Remme W, Zannad F, Neaton J, Martinez F, Roniker B, Bittman R, Hurley S, Kleiman J, Gatlin M. Eplerenone, a selective aldosterone blocker, in patients with left ventricular dysfunction after myocardial infarction. N Engl J Med. 2003;348:1309-1321.
54. Wang W. Chronic administration of aldosterone depresses baroreceptor reflex function in the dog. Hypertension. 1994;24:571-575.
55. Yee KM, Struthers AD. Aldosterone blunts the baroreflex response in man. Clin Sci (Lond). 1998;95:687-692.
56. Rigsby CS, Pollock DM, Dorrance AM. Spironolactone improves structure and increases tone in the cerebral vasculature of male spontaneously hypertensive stroke-prone rats. Microvasc Res. 2007;73:198-205.
57. Gekle M, Freudinger R, Mildenberger S, Silbernagl S. Rapid actions of aldosterone on cells from renal epithelium: the possible role of EGF-receptor signaling. Steroids. 2002;67:499-504.
58. Grossmann C, Freudinger R, Mildenberger S, Krug AW, Gekle M. Evidence for epidermal growth factor receptor as negative-feedback control in aldosterone-induced Na+ reabsorption. Am J Physiol Renal Physiol. 2004;286:F1226-F1231.