Deficiency of bradykinin receptor B2 is not detrimental in experimental stroke

Hypertension

Volumn 51, Issue 5, 2008, Pages

  Kleinschnitz, Christoph ^a   Austinat, Madeleine ^a   Bader, Michael ^b   Renné, Thomas ^a   Stoll, Guido ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BRADYKININ B2 RECEPTOR; TRIPHENYLTETRAZOLIUM;

DISEASE COURSE; EXPERIMENTAL STUDY; LASER DOPPLER FLOWMETRY; LETTER; MIDDLE CEREBRAL ARTERY OCCLUSION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFICIENCY; STAINING; STROKE; VOLUMETRY;

ANIMALS; BRAIN; DISEASE MODELS, ANIMAL; INFARCTION, MIDDLE CEREBRAL ARTERY; MICE; MICE, KNOCKOUT; RECEPTOR, BRADYKININ B2; STROKE; TIME FACTORS;

EID: 42349095662     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.107.109090     Document Type: Letter

References (5)

1. Sobey CG. Bradykinin B2 receptor antagonism: a new direction for acute stroke therapy? Br J Pharmacol. 2003;139:1369-1371.
2. Xia CF, Smith RS Jr, Shen B, Yang ZR, Borlongan CV, Chao L, Chao J. Postischemic brain injury is exacerbated in mice lacking the kinin B2 receptor. Hypertension. 2006;47:752-761.
3. Paxinos G, Franklin K. The Mouse Brain in Stereotaxic Coordinates. 2nd ed. San Diego, CA: Academic Press; 2004
4. Kleinschnitz C, Stoll G, Bendszus M, Schuh K, Pauer HU, Burfeind P, Renné C, Gailani D, Nieswandt B, Renné T. Targeting coagulation factor XII provides protection from pathological thrombosis in cerebral ischemia without interfering with hemostasis. J Exp Med. 2006;2033:513-518.
5. Prüss H, Prass K, Ghaeni L, Milosevic M, Muselmann C, Freyer D, Royl G, Reuter U, Baeva N, Dirnagl U, Meisel A, Priller J. Inducible nitric oxide synthase does not mediate brain damage after transient focal cerebral ischemia in mice. J Cereb Blood Flow Metab. Epub ahead of print, doi: 10.1038/sj.jcbfm.9600550.