An ultrastructural investigation of tissue-engineered pulp constructs implanted within endodontically treated teeth

Journal of the American Dental Association

Volumn 139, Issue 4, 2008, Pages 457-465

  Gotlieb, Eric L ^a   Murray, Peter E ^b   Namerow, Kenneth M ^b   Kuttler, Sergio ^b   Garcia Godoy, Franklin ^b  

^a Exeter Endodontics   (United States)

^b NOVA SOUTHEASTERN UNIVERSITY   (United States)

Author keywords

Dental pulp tissue constructs; Endodontics; Pulpitis; Root canal; Stem cells

Indexed keywords

EID: 42349088258     PISSN: 00028177     EISSN: None     Source Type: Journal    
DOI: 10.14219/jada.archive.2008.0189     Document Type: Article

References (33)

1. Mao JJ, Giannobile WV, Helms JA, et al. Craniofacial tissue engineering by stem cells. J Dent Res 2006;85(11):966-979.
2. Rao MS. Stem sense: a proposal for the classification of stem cells. Stem Cells Dev 2004;13(5):452-455.
3. Gronthos S, Brahim J, Li W, et al. Stem cell properties of human dental pulp stem cells. J Dent Res 2002;81(8):531-535.
4. Murray PE, Garcia-Godoy F. Stem cell responses in tooth regeneration. Stem Cells Dev 2004;13(3):255-262.
5. Miura M, Gronthos S, Zhao M, et al. SHED: stem cells from human exfoliated deciduous teeth. Proc Natl Acad Sci U S A 2003;100(10): 5807-5812.
6. Shi S, Bartold PM, Miura M, Seo BM, Robey PG, Gronthos S. The efficacy of mesenchymal stem cells to regenerate and repair dental structures. Orthod Craniofac Res 2005;8(3):191-199.
7. Zhang W, Walboomers XF, van Kuppevelt TH, Daamen WF, Bian Z, Jansen JA. The performance of human dental pulp stem cells on different three-dimensional scaffold materials. Biomaterials 2006;27(33): 5658-5668.
8. Hee CK, Jonikas MA, Nicoll SB. Influence of three-dimensional scaffold on the expression of osteogenic differentiation markers by human dermal fibroblasts. Biomaterials 2006;27(6):875-884.
9. Taylor MS, Daniels AU, Andriano KP, Heller J. Six bioabsorbable polymers: in vitro acute toxicity of accumulated degradation products. J Appl Biomater 1994;5(2):151-157.
10. Athanasiou KA, Niederauer GG, Agrawal CM. Sterilization, toxicity, biocompatibility and clinical applications of polylactic acid/polyglycolic acid copolymers. Biomaterials 1996;17(2):93-102.
11. Bhang SH, Lim JS, Choi CY, Kwon YK, Kim BS. The behavior of neural stem cells on biodegradable synthetic polymers. J Biomater Sci Polym Ed 2007;18(2):223-239.
12. Buurma B, Gu K, Rutherford RB. Transplantation of human pulpal and gingival fibroblasts attached to synthetic scaffolds. Eur J Oral Sci 1999;107(4):282-289.
13. Young CS, Terada S, Vacanti JP, Honda M, Bartlett JD, Yelick PC. Tissue engineering of complex tooth structures on biodegradable polymer scaffolds. J Dent Res 2002;81(10):695-700.
14. Duailibi MT, Duailibi SE, Young CS, Bartlett JD, Vacanti JP, Yelick PC. Bioengineered teeth from cultured rat tooth bud cells. J Dent Res 2004;83(7):523-528.
15. Gomillion CT, Burg KJ. Stem cells and adipose tissue engineering. Biomaterials 2006;27(36):6052-6063.
16. Smith AJ, Matthews JB, Hall RC. Transforming growth factor-betal (TGF-betal) in dentine matrix. Ligand activation and receptor expression. Eur J Oral Sci 1998;106(suppl 1):179-184.
17. Smith AJ, Murray PE, Sloan AJ, Matthews JB, Zhao S. Transdentinal stimulation of tertiary dentinogenesis. Adv Dent Res 2001; 15:51-54.
18. Nakashima M, Reddi AH. The application of bone morphogenetic proteins to dental tissue engineering. Nat Biotechnol 2003;21(9): 1025-1032.
19. Nakashima M, Nagasawa H, Yamada Y, Reddi AH. Regulatory role of transforming growth factor-beta, bone morphogenetic protein-2, and protein-4 on gene expression of extracellular matrix proteins and differentiation of dental pulp cells. Dev Biol 1994;162(1):18-28.
20. Sloan AJ, Smith AJ. Stimulation of the dentine-pulp complex of rat incisor teeth by transforming growth factor-beta isoforms 1-3 in vitro. Arch Oral Biol 1999;44(2): 149-156.
21. Nakashima M. Bone morphogenetic proteins in dentin regeneration for potential use in endodontic therapy. Cytokine Growth Factor Rev 2005;16(3):369-376.
22. Murray PE, Garcia-Godoy F, Hargreaves KM. Regenerative endodontics: a review of current status and a call for action. J Endod 2007;33(4):377-390.
23. Shabahang S, Torabinejad M. Effect of MTAD on Enterococcus faecalis-contaminated root canals of extracted human teeth. J Endod 2003;29(9):576-597.
24. Nakashima M. Induction of dentine in amputated pulp of dogs by recombinant human bone morphogenetic proteins-2 and -4 with collagen matrix. Arch Oral Biol 1994;39(12):1085-1089.
25. Banchs F, Trope M. Revascularization of immature permanent teeth with apical periodontitis: new treatment protocol? J Endod 2004;30(4): 196-200.
26. Chueh LH, Huang GT. Immature teeth with periradicular periodontitis or abscess undergoing apexogenesis: a paradigm shift. J Endod 2006;32(12):1205- 1213.
27. Hørsted P, Nygaard-Ostby B. Tissue formation in the root canal after total pulpectomy and partial root filling. Oral Surg Oral Med Oral Pathol 1978;46(2):275-282.
28. Nygaard-Ostby B, Hjortdal O. Tissue formation in the root canal following pulp removal. Scand J Dent Res 1971;79(5):333-349.
29. Nie X, Tian W, Zhang Y, et al. Induction of transforming growth factor-beta 1 on dentine pulp cells in different culture patterns. Cell Biol Int 2006;30(4):295-300.
30. Hoshino E, Kurihara-Ando N, Sato I, et al. In-vitro antibacterial susceptibility of bacteria taken from infected root dentine to a mixture of ciprofloxacin, metronidazole and minocycline. Int Endod J 1996;29(2):125-130.
31. Bueno EM, Laevsky G, Barabino GA. Enhancing cell seeding of scaffolds in tissue engineering through manipulation of hydrodynamic parameters. J Biotechnol 2007;129(3):516-531.
32. Polykandriotis E, Arkudas A, Horch RE, Stürzl M, Kneser U. Autonomously vascularized cellular constructs in tissue engineering: opening a new perspective for biomedical science. J Cell Mol Med 2007;11(1):6-20.
33. Sonoyama W, Liu Y, Fang D, et al. Mesenchymal stem cell-mediated functional tooth regeneration in swine. PLoS ONE 2006;1:e79.