Renal cytokine profile in an endotoxemic porcine model

Acta Anaesthesiologica Scandinavica

Volumn 52, Issue 5, 2008, Pages 614-620

  Granfeldt, A ^a   Ebdrup, L ^a   Tonnesen E ^a   Wogensen, L ^a  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

Author keywords

Acute kidney failure; Cytokines; Endotoxemia; Immunohistochemistry; Swine

Indexed keywords

INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 10; INTERLEUKIN 1BETA; TUMOR NECROSIS FACTOR ALPHA;

ANESTHESIA; ANIMAL CELL; ANIMAL TISSUE; ARTERIOLE; ARTICLE; ARTIFICIAL VENTILATION; CELLULAR DISTRIBUTION; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENDOTHELIUM CELL; ENDOTOXEMIA; EUTHANASIA; GLOMERULUS; GLOMERULUS FILTRATION; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; KIDNEY TUBULE ABSORPTION; KIDNEY TUBULE CELL; LEUKOCYTE; MESANGIUM CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SWINE;

ANALYSIS OF VARIANCE; ANIMALS; CYTOKINES; DISEASE MODELS, ANIMAL; ENDOTOXEMIA; ESCHERICHIA COLI; IMMUNOHISTOCHEMISTRY; KIDNEY; LEUKOCYTES; LIPOPOLYSACCHARIDES; RANDOM ALLOCATION; SINGLE-BLIND METHOD; SWINE;

EID: 42249109180     PISSN: 00015172     EISSN: 13996576     Source Type: Journal    
DOI: 10.1111/j.1399-6576.2008.01625.x     Document Type: Article

References (41)

1. Klenzak J, Himmelfarb J. Sepsis and the kidney. Crit Care Clin 2005 21 : 211 22.
2. Rangel-Frausto MS, Pittet D, Costigan M et al. The natural history of the systemic inflammatory response syndrome (SIRS). A prospective study. JAMA 1995 273 : 117 23.
3. Bagshaw SM, Uchino S, Bellomo R et al. Septic acute kidney injury in critically ill patients: clinical characteristics and outcomes. Clin J Am Soc Nephrol 2007 2 : 431 9.
4. Schrier RW, Wang W. Acute renal failure and sepsis. N Engl J Med 2004 351 : 159 69.
5. Langenberg C, Bellomo R, May C et al. Renal blood flow in sepsis. Crit Care 2005 9 : R363 74.
6. Chawla LS, Seneff MG, Nelson DR et al. Elevated plasma concentrations of IL-6 and elevated APACHE II score predict acute kidney injury in patients with severe sepsis. Clin J Am Soc Nephrol 2007 2 : 22 30.
7. Brix-Christensen V, Vestergaard C, Andersen SK et al. Evidence that acute hyperinsulinaemia increases the cytokine content in essential organs after an endotoxin challenge in a porcine model. Acta Anaesthesiol Scand 2005 49 : 1429 35.
8. Kohan DE. Role of endothelin and tumour necrosis factor in the renal response to sepsis. Nephrol Dial Transplant 1994 9 (Suppl. 4) : 73 7.
9. Cunningham PN, Wang Y, Guo R et al. Role of toll-like receptor 4 in endotoxin-induced acute renal failure. J Immunol 2004 172 : 2629 35.
10. Cunningham PN, Dyanov HM, Park P et al. Acute renal failure in endotoxemia is caused by TNF acting directly on TNF receptor-1 in kidney. J Immunol 2002 168 : 5817 23.
11. Knotek M, Rogachev B, Wang W et al. Endotoxemic renal failure in mice: role of tumor necrosis factor independent of inducible nitric oxide synthase. Kidney Int 2001 59 : 2243 9.
12. Scumpia PO, Moldawer LL. Biology of interleukin-10 and its regulatory roles in sepsis syndromes. Crit Care Med 2005 33 : S468 71.
13. Irikura VM, Lagraoui M, Hirsh D. The epistatic interrelationships of IL-1, IL-1 receptor antagonist, and the type I IL-1 receptor. J Immunol 2002 169 : 393 8.
14. Poole S, Bird TA, Selkirk S et al. Fate of injected interleukin 1 in rats: sequestration and degradation in the kidney. Cytokine 1990 2 : 416 22.
15. Reimers J, Wogensen LD, Welinder B et al. The pharmacokinetics, distribution and degradation of human recombinant interleukin 1 beta in normal rats. Scand J Immunol 1991 34 : 597 610.
16. Baud L, Oudinet JP, Bens M et al. Production of tumor necrosis factor by rat mesangial cells in response to bacterial lipopolysaccharide. Kidney Int 1989 35 : 1111 8.
17. Brix-Christensen V, Andersen SK, Andersen R et al. Acute hyperinsulinemia restrains endotoxin-induced systemic inflammatory response: an experimental study in a porcine model. Anesthesiology 2004 100 : 861 70.
18. Muller AM, Hermanns MI, Skrzynski C et al. Expression of the endothelial markers PECAM-1, vWf, and CD34 in vivo and in vitro. Exp Mol Pathol 2002 72 : 221 9.
19. Holthofer H, Sainio K, Miettinen A. The glomerular mesangium: studies of its developmental origin and markers in vivo and in vitro. APMIS 1995 103 : 354 66.
20. Hoste EA, Kellum JA. Acute kidney injury: epidemiology and diagnostic criteria. Curr Opin Crit Care 2006 12 : 531 7.
21. Kita T, Tanaka N, Nagano T. The immunocytochemical localization of tumour necrosis factor and leukotriene in the rat kidney after treatment with lipopolysaccharide. Int. J. Exp. Pathol. 1993 74 : 471 479.
22. Kayama F, Yoshida T, Kodama Y, Matsul T, Matheson JM, Luster MI. Pro-inflammatory cytokines and interleukin 6 in the renal response to bacterial endotoxin. Cytokine 1997 9 : 688 95.
23. Fouqueray B, Boutard V, Philippe C et al. Mesangial cell-derived interleukin-10 modulates mesangial cell response to lipopolysaccharide. Am J Pathol 1995 147 : 176 82.
24. Noiri E, Kuwata S, Nosaka K et al. Tumor necrosis factor-alpha mRNA expression in lipopolysaccharide-stimulated rat kidney. Chronological analysis of localization. Am J Pathol 1994 144 : 1159 66.
25. Volk T, Kox WJ. Endothelium function in sepsis. Inflamm. Res. 2000 49 : 185 198.
26. Niemir ZI, Stein H, Dworacki G et al. Podocytes are the major source of IL-1 alpha and IL-1 beta in human glomerulonephritides. Kidney Int 1997 52 : 393 403.
27. Cunningham PN, Holers VM, Alexander JJ et al. Complement is activated in kidney by endotoxin but does not cause the ensuing acute renal failure. Kidney Int 2000 58 : 1580 7.
28. Wu X, Guo R, Wang Y et al. The role of ICAM-1 in endotoxin-induced acute renal failure. Am J Physiol Renal Physiol 2007 293 : 1262 71.
29. Linas SL, Whittenburg D, Repine JE. Role of neutrophil derived oxidants and elastase in lipopolysaccharide-mediated renal injury. Kidney Int 1991 39 : 618 23.
30. Ferraiolo BL, McCabe J, Hollenbach S et al. Pharmacokinetics of recombinant human tumor necrosis factor-alpha in rats. Effects of size and number of doses and nephrectomy. Drug Metab Dispos 1989 17 : 369 72.
31. Bocci V. Metabolism of protein anticancer agents. Pharmacol Ther 1987 34 : 1 49.
32. Kudo S, Mizuno K, Hirai Y et al. Clearance and tissue distribution of recombinant human interleukin 1 beta in rats. Cancer Res 1990 50 : 5751 5.
33. Newton RC, Uhl J, Covington M et al. The distribution and clearance of radiolabeled human interleukin-1 beta in mice. Lymphokine Res 1988 7 : 207 16.
34. Mariano F, Guida G, Donati D et al. Production of platelet-activating factor in patients with sepsis-associated acute renal failure. Nephrol Dial Transplant 1999 14 : 1150 7.
35. Brenner BM, Bohrer MP, Baylis C et al. Determinants of glomerular permselectivity: insights derived from observations in vivo. Kidney Int 1977 12 : 229 37.
36. Chang RL, Ueki IF, Troy JL et al. Permselectivity of the glomerular capillary wall to macromolecules. II. Experimental studies in rats using neutral dextran. Biophys J 1975 15 : 887 906.
37. Andersen SR, Lambrecht LJ, Swan SK et al. Disposition of recombinant human interleukin-10 in subjects with various degrees of renal function. J Clin Pharmacol 1999 39 : 1015 20.
38. Chiu PJ, Radwanski E, Tetiloff G et al. Interleukin-10 pharmacokinetics in intact and nephrectomized mice. Eur Cytokine Netw 1996 7 : 67 9.
39. Kim DC, Reitz B, Carmichael DF et al. Kidney as a major clearance organ for recombinant human interleukin-1 receptor antagonist. J Pharm Sci 1995 84 : 575 80.
40. Nielsen JS, Larsson A, Brix-Christensen V, Nyengaard JR, Ledet T, Tonnesen E. Endotoxemia-induced lymphocyte apoptosis is augmented by a hyperinsulinemic-euglycemic clamp. Anesthesiology 2005 102 : 768 73.
41. Dalmose AL, Hvistendahl JJ, Olsen LH, Eskild-Jensen A, Djurhuus JC, Swindle MM. Surgically induced urologic models in swine. J Invest Surg 2000 13 : 133 45.