Evaluation of a venous-return assist device to treat severe post-thrombotic syndrome (VENOPTS): A randomized controlled trial

Thrombosis and Haemostasis

Volumn 99, Issue 3, 2008, Pages 623-629

  O'Donnell, Martin J ^a,d   McRae, Simon ^a   Kahn, Susan R ^b   Julian, Jim A ^a   Kearon, Clive ^a   MacKinnon, Betsy ^a   Magier, Debbie ^c   Strulovich, Carla ^b   Lyons, Theresa ^a   Robinson, Sandra ^c   Hirsh, Jack ^a   Ginsberg, Jeffrey S ^a,b  

^a MCMASTER UNIVERSITY   (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c HAMILTON HEALTH SCIENCES   (Canada)

^d HENDERSON RESEARCH CENTRE   (Canada)

Author keywords

Clinical studies; Deep vein thrombosis; Venous thrombosis

Indexed keywords

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; COMPRESSION GARMENT; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DEVICE; DISEASE SEVERITY; FEMALE; HUMAN; MALE; MULTICENTER STUDY; POSTTHROMBOSIS SYNDROME; PRIORITY JOURNAL; QUALITY OF LIFE; QUESTIONNAIRE; RANDOMIZATION; RANDOMIZED CONTROLLED TRIAL; RATING SCALE; THERAPY EFFECT; TREATMENT OUTCOME; VENOUS RETURN ASSIST DEVICE;

ADULT; AGED; CANADA; CROSS-OVER STUDIES; DOUBLE-BLIND METHOD; EQUIPMENT DESIGN; FEMALE; HUMANS; INTERMITTENT PNEUMATIC COMPRESSION DEVICES; MALE; MIDDLE AGED; PATIENT COMPLIANCE; PATIENT SATISFACTION; POSTTHROMBOTIC SYNDROME; QUALITY OF LIFE; QUESTIONNAIRES; SEVERITY OF ILLNESS INDEX; STOCKINGS, COMPRESSION; TIME FACTORS; TREATMENT OUTCOME;

EID: 42249093687     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH07-09-0546     Document Type: Article

References (17)

1. Prandoni P, Lensing AW, Cogo A, et al. The long-term clinical course of acute deep venous thrombosis. Ann Intern Med 1996; 125: 1-7.
2. Roumen-Klapper EM, de Heijer M, Janssen MC, et al. The post-thrombotic syndrome: incidence and prognostic value of non-invasive venous examinations in a six-year follow-up study. Thromb Haemost 2005; 94: 825-830.
3. Leizorovicz A. Long-term consequences of deep vein thrombosis. Haemostasis 1998; 28 (Suppl 3): 1-7.
4. Olin JW, Beusterien KM, Childs MB, et al. Medical costs of treating venous stasis ulcers: evidence from a retrospective cohort study. Vasc Med 1999; 4: 1-7.
5. Kahn SR, Ginsberg JS The Post-thrombotic syndrome: current knowledge, controversies, and directions for future research. Blood Rev 2002; 16: 155-165.
6. Kahn SR. The post-thrombotic syndrome: the forgotten morbidity of deep vein thrombosis. J Thromb Thrombolysis 2006; 21: 41-48.
7. Kahn SR, Hirsch A, Shrier I. Effect of post-thrombotic syndrome on health-related quality of life after deep venous thrombosis. Arch Intern Med 2002; 162: 1144-1148.
8. Kahn SR, Ducruet T, Lamping DL, et al. Prospective evaluation of health-related quality of life in patients with deep venous thrombosis. Arch Intern Med 2005; 165: 1173-1178.
9. Brandjes DPM, Büller HR, Heijboer H, et al. Randomised trial of effect of compression stockings in subjects with symptomatic proximal-vein thrombosis. Lancet 1997; 349: 759-762.
10. Prandoni P, Lensing AW, Prins MH, et al. Below-knee elastic compression stockings to prevent the post-thrombotic syndrome: a randomized, controlled trial. Ann Intern Med 2004; 141: 249-256.
11. Ginsberg JS, Hirsh J, Julian J, et al Prevention and treatment of Postphlebitic Syndrome. Results of a 3-Part Study. Arch Intern Med 2001; 161: 2105-2109.
12. Ginsberg JS, Magier D, McKinnon B, et al. Intermittent compression units for severe post-thrombotic syndrome: a randomized crossover study. CMAJ 1999; 160: 1303-1306.
13. O'Donnell M, Ginsberg JS, Saringer J, et al Effects of a novel Venous-return assist device ('Venowave') on lower limb venous flow in Subjects with post-thrombotic syndrome. Blood 2002; 100 (11 Suppl): 3950.
14. O'Donnell M, Ginsberg JS, Saringer J, et al. Evaluation of a venous-return assist device (Venowave) to treat post-thrombotic syndrome: A phase II study. Poster presentation at the International Society of Thrombosis and Haemostasis, July 2003.
15. Villalta S, Bagatella P, Piccioli A, et al. Assessment and validity and reproducibility of a clinical scale for the post-thrombotic syndrome. Hemostasis 1994; 24 (Suppl 1): 158a Abstract.
16. Lamping DL, Schroter S, Kurz X, et al. Evaluation of outcomes in chronic venous disorders of the leg: development of a scientifically rigorous, patient-reported measure of symptoms and quality of life. J Vasc Surg 2003; 37: 410-419.
17. Kahn SR, Lamping DL, Ducruet T, et al. VEINESQOL/Sym questionnaire was a reliable and valid disease-specific quality of life measure for deep venous thrombosis. J Clin Epidemiol 2006; 59: 1049-1056.