Aberrant expression of α-fetoprotein in intrahepatic cholangiocarcinoma: An exceptional occurrence

International Journal of Surgical Pathology

Volumn 16, Issue 2, 2008, Pages 194-198

  Vij, Kiran ^a   Wang, Hanlin L ^a,b  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Cedars Sinai Medical Center   (United States)

Author keywords

fetoprotein; Cholangiocarcinoma; Liver

Indexed keywords

ALPHA FETOPROTEIN; CA 19-9 ANTIGEN; CYTOKERATIN 19;

ADULT; ARTICLE; BILE DUCT CARCINOMA; CASE REPORT; COMPUTER ASSISTED TOMOGRAPHY; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; TUMOR CELL;

ADULT; ALPHA-FETOPROTEINS; BILE DUCT NEOPLASMS; BILE DUCTS, INTRAHEPATIC; CHOLANGIOCARCINOMA; HUMANS; MALE; NEOPLASM PROTEINS; TOMOGRAPHY, X-RAY COMPUTED; TUMOR MARKERS, BIOLOGICAL;

EID: 42249088062     PISSN: 10668969     EISSN: None     Source Type: Journal    
DOI: 10.1177/1066896907304519     Document Type: Article

References (12)

1. Gitlin D., Pericelli A., Gitlin M. Synthesis of alpha-fetoprotein by liver, yolk sac and gastrointestinal tract of the human conceptus. Cancer Res. 1972 ; 32: 979-982.
2. Johnson PJ The role of serum alpha-fetoprotein estimation in the diagnosis and management of hepatocellular carcinoma. Clin Liver Dis. 2001 ; 5: 145-159.
3. Wee A. Diagnostic utility of immunohistochemistry in hepatocellular carcinoma, its variants and their mimics. Appl Immunohistochem Mol Morphol. 2006 ; 14: 266-272.
4. Okuda K. ; Liver Cancer Study Group of Japan. Primary liver cancers in Japan. Cancer. 1980 ; 45: 2663-2669.
5. Yamamoto M., Ariizumi S., Otsubo T., et al. Intrahepatic cholangiocarcinoma diagnosed preoperatively as hepatocellular carcinoma. J Surg Oncol. 2004 ; 87: 80-83.
6. Lau SK, Prakash S., Geller SA, Alsabeh R. Comparative immunohistochemical profile of hepatocellular carcinoma, cholangiocarcinoma, and metastatic adenocarcinoma. Hum Pathol. 2002 ; 33: 1175-1181.
7. Porcell AI, De Young BR, Proca DM, Frankel WL Immunohistochemical analysis of hepatocellular and adenocarcinoma in the liver: MOC31 compares favorably with other putative markers. Mod Pathol. 2000 ; 13: 773-778.
8. Nonomura A., Mizukami Y., Matsubara F., et al. Human chorionic gonadotropin and alpha-fetoprotein in cholangiocarcinoma in relation to the expression of ras p21: an immunohistochemical study. Liver. 1989 ; 9: 205-215.
9. Kono K., Amemiya H., Sekikawa T., et al. Clinicopathologic features of gastric cancers producing alpha-fetoprotein. Dig Surg. 2002 ; 19: 359-365.
10. Ooi A., Nakanishi I., Sakamoto N., et al. α-fetoprotein (AFP)-producing gastric carcinoma: is it hepatoid differentiation ? Cancer. 1990 ; 65: 1741-1747.
11. Sell S., Dunsford HA Evidence for the stem cell origin of hepatocellular carcinoma and cholangiocarcinoma. Am J Pathol. 1989 ; 134: 1347-1363.
12. Vessey CJ, de la Hall PM Hepatic stem cells: a review. Pathology. 2001 ; 33: 130-141.