Comparison of breath testing with fructose and high fructose corn syrups in health and IBS

Neurogastroenterology and Motility

Volumn 20, Issue 5, 2008, Pages 505-511

  Skoog, S M ^a   Bharucha, A E ^a,b   Zinsmeister, A R ^a  

^a MAYO CLINIC   (United States)

^b Clinical Enteric Neuroscience Translational and Epidemiological Research Mayo Clinic   (United States)

Author keywords

Bloating; Fructose intolerance; Functional bowel disorder; High fructose corn syrup; Irritable bowel syndrome

Indexed keywords

FRUCTOSE CORN SYRUP; HYDROGEN; SWEETENING AGENT; UNCLASSIFIED DRUG;

ADULT; ARTICLE; BLOATING; BREATH ANALYSIS; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DISEASE ASSOCIATION; DOUBLE BLIND PROCEDURE; FEMALE; FOOD INTAKE; GASTROINTESTINAL SYMPTOM; HEREDITARY FRUCTOSE INTOLERANCE; HUMAN; HYDROGEN BREATH TEST; IRRITABLE COLON; MALE; MEDICAL ASSESSMENT; PREVALENCE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SCORING SYSTEM; VISUAL ANALOG SCALE;

ADULT; BREATH TESTS; CROSS-OVER STUDIES; DOUBLE-BLIND METHOD; FEMALE; FRUCTOSE; FRUCTOSE INTOLERANCE; HEALTH STATUS; HUMANS; IRRITABLE BOWEL SYNDROME; MALE; ZEA MAYS;

EID: 42249083760     PISSN: 13501925     EISSN: 13652982     Source Type: Journal    
DOI: 10.1111/j.1365-2982.2007.01074.x     Document Type: Article

References (28)

1. Park YK, Yetley EA. Intakes and food sources of fructose in the United States. Am J Clin Nutr 1993 58:737S 47S.
2. Vuilleumier S. Worldwide production of high-fructose syrup and crystalline fructose. Am J Clin Nutr 1993 58:733S 6S.
3. Wasserman D, Hoekstra JH, Tolia V et al. Molecular analysis of the fructose transporter gene (GLUT5) in isolated fructose malabsorption. J Clin Invest 1996 98:2398 402.
4. Holdsworth CD, Dawson AM. Absorption of fructose in man. Proc Soc Exp Biol Med 1965 118:142 5.
5. Rumessen JJ, Gudmand-Hoyer E. Absorption capacity of fructose in healthy adults. Comparison with sucrose and its constituent monosaccharides. Gut 1986 27:1161 8.
6. Ravich WJ, Bayless TM, Thomas M. Fructose: incomplete intestinal absorption in humans. Gastroenterology 1983 84:26 9.
7. Truswell AS, Seach JM, Thorburn AW. Incomplete absorption of pure fructose in healthy subjects and the facilitating effect of glucose. Am J Clin Nutr 1988 48:1424 30.
8. Rumessen JJ, Gudmand-Hoyer E. Functional bowel disease: malabsorption and abdominal distress after ingestion of fructose, sorbitol, and fructose-sorbitol mixtures. Gastroenterology 1988 95:694 700.
9. Fernandez-Banares F, Esteve-Pardo M, Humbert P, de Leon R, Llovet JM, Gassull MA. Role of fructose-sorbitol malabsorption in the irritable bowel syndrome [comment] Gastroenterology 1991 101:1453 4.
10. Fernandez-Banares F, Esteve-Pardo M, de Leon R et al. Sugar malabsorption in functional bowel disease: clinical implications. Am J Gastroenterol 1993 88:2044 50.
11. Choi YK, Johlin FC Jr., Summers RW, Jackson M, Rao SS. Fructose intolerance: an under-recognized problem. Am J Gastroenterol 2003 98:1348 53.
12. Holdsworth CD, Dawson AM. The absorption of monosaccharides in man. Clin Sci 1964 27:371 9.
13. Kneepkens CM, Vonk RJ, Fernandes J. Incomplete intestinal absorption of fructose. Arch Dis Child 1984 59:735 8.
14. Hanover LM, White JS. Manufacturing, composition, and applications of fructose. Am J Clin Nutr 1993 58:724S 32S.
15. Drossman DA, Camilleri M, Mayer EA, Whitehead WE. AGA technical review on irritable bowel syndrome. Gastroenterology 2002 123:2108 31.
16. Zigmond A, Snaith R. The Hospital Anxiety and Depression Scale. Acta Psychiatr Scand 1982 67:361 70.
17. Bharucha AE, Locke GR, Seide B, Zinsmeister AR. A new questionnaire for constipation and fecal incontinence. Aliment Pharmacol Ther 2004 20:355 64.
18. Strocchi A, Corazza G, Ellis CJ, Gasbarrini G, Levitt MD. Detection of malabsorption of low doses of carbohydrate: accuracy of various breath H2 criteria [see comment] Gastroenterology 1993 105:1404 10.
19. Bardhan KD, Bodemar G, Geldof H et al. A double-blind, randomized, placebo-controlled dose-ranging study to evaluate the efficacy of alosetron in the treatment of irritable bowel syndrome. Aliment Pharmacol Ther 2000 14:23 34.
20. Design of Treatment Trials Committee:Irvine EJ, Whitehead WE, Chey WD et al. Design of treatment trials for functional gastrointestinal disorders. Gastroenterology 2006 130:1538 51.
21. Thompson WG, Longstreth GF, Drossman DA, Heaton KW, Irvine EJ, Muller-Lissner SA. Functional bowel disorders and functional abdominal pain. Gut 1999 45:1143 7.
22. Romagnuolo J, Schiller D, Bailey RJ. Using breath tests wisely in a gastroenterology practice: an evidence-based review of indications and pitfalls in interpretation. Am J Gastroenterol 2002 97:1113 26.
23. Summers RW, Johlin FC Jr. Fructose intolerance is due to rapid orocecal transit and not small bowel bacterial overgrowth. Gastroenterology 2001 120:A-1369.
24. Evans PR, Piesse C, Bak YT, Kellow JE. Fructose-sorbitol malabsorption and symptom provocation in irritable bowel syndrome: relationship to enteric hypersensitivity and dysmotility. Scand J Gastroenterol 1998 33:1158 63.
25. Fine KD, Santa Ana CA, Porter JL, Fordtran JS. Mechanism by which glucose stimulates the passive absorption of small solutes by the human jejunum in vivo. Gastroenterology 1994 107:389 95.
26. Hoekstra JH, van den Aker JH. Facilitating effect of amino acids on fructose and sorbitol absorption in children. J Pediatr Gastroenterol Nutr 1996 23:118 24.
27. Shi X, Schedl HP, Summers RM et al. Fructose transport mechanisms in humans. Gastroenterology 1997 113:1171 9.
28. Elias E, Gibson GJ, Greenwood LF, Hunt JN, Tripp JH. The slowing of gastric emptying by monosaccharides and disaccharides in test meals. J Physiol 1968 194:317 26.