Molecular mechanism of reversing multi-drug resistance of K562/AO2 by puerarin

Journal of Central South University (Medical Sciences)

Volumn 33, Issue 3, 2008, Pages 216-221

  Chen, Jin Wei ^a   Tao, Shi ^a   Luo, Rong ^a   Zhang, Guang Sen ^a   Xu, Yun Xiao ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

K562 AO2; Molecular mechanism; Multi drug resistance; Puerarin; Reversal

Indexed keywords

ANTINEOPLASTIC AGENT; BIRC5 PROTEIN, HUMAN; GLYCOPROTEIN P; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; ISOFLAVONE DERIVATIVE; MICROTUBULE ASSOCIATED PROTEIN; PUERARIN;

ARTICLE; BIOSYNTHESIS; CELL STRAIN K 562; DRUG EFFECT; DRUG RESISTANCE; GENETICS; HUMAN; METABOLISM; MULTIDRUG RESISTANCE;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; HUMANS; ISOFLAVONES; K562 CELLS; MICROTUBULE-ASSOCIATED PROTEINS; NF-KAPPA B; P-GLYCOPROTEINS;

EID: 42149186404     PISSN: 16727347     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (9)

1. Yu Z. Induction of apoptosis by puerarin in colon cancer HT-29 cells [J]. Cancer lett, 2005, 35 (2): 245-251.
2. JIAO Lu. Study on the differentiation and migration of cell -cycle of HL-60 cell line induced by the effect of S86019 of puerarin [J]. Chin J Hematol, 1990, 11 (2): 83-85.
3. κB activity on K562/AO2 cells and effect of puerarin in reversing the multidrug resistance of K562/ AO2 cell [J]. Chin J Hematol, 2006, 27 (7): 482-484.
4. κB signaling pathway may contribute to the mediation of paclitaxel - induced apoptosis in solid tumor cells [J]. Cancer Res, 2000, 60 (1): 4426-4432.
5. κB sensitizes non-small cell lung cancer cells to chemotherapy-induced apoptosis [J]. Ann Thorac Surg, 2000, 70 (3): 930-936.
6. κB and death responses in A 20 deficient mice[J]. Science, 2000, 289 (10): 2350-2354.
7. Prasain J K, Jones K, Kirk M, et al. Profiling and quantification of isoflavo - noids in kudzu dietary supplements by high-performance liquid chromatography and electrospray ionization tandem mass spectrometry [J]. Agric Food Chem, 2003, 51 (15): 4213-4218.
8. κB activation induced by various carcinogens and inflamatory agents through inhibithion of IkBa kinase and P65 phosphorylation [J]. Biol Chem, 2004, 279 (6): 4750-4759.
9. + lymphocytes [J]. Immunology, 2000, 165 (4): 1743-1754.