Clevudine is efficiently phosphorylated to the active triphosphate form in primary human hepatocytes

Antiviral Therapy

Volumn 13, Issue 2, 2008, Pages 263-269

  Niu, Congrong ^a   Murakami, Eisuke ^a   Furman, Phillip A ^a  

^a PHARMASSET INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CLEVUDINE; DRUG METABOLITE; NUCLEOSIDE DERIVATIVE;

ADULT; AGED; ARTICLE; CELL LINE; CLINICAL ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EXPOSURE; DRUG HALF LIFE; DRUG METABOLISM; FEMALE; HEPATITIS B VIRUS; HEPATOMA CELL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IN VITRO STUDY; ISOTOPE LABELING; LIVER; LIVER CELL; MALE; PHOSPHORYLATION; PRIORITY JOURNAL;

ADOLESCENT; AGED; ANTIVIRAL AGENTS; ARABINOFURANOSYLURACIL; CELL LINE, TUMOR; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HALF-LIFE; HEPATOCYTES; HUMANS; MALE; MIDDLE AGED; PHOSPHORYLATION; POLYPHOSPHATES;

EID: 42149178596     PISSN: 13596535     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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