Toxicity, DNA binding, and cell proliferation in male F344 rats following short-term gavage exposures to trans-2-hexenal

Toxicologic Pathology

Volumn 36, Issue 2, 2008, Pages 232-246

  Stout, Matthew D ^a,d   Bodes, Elmarie ^a,e   Schoonhoven, Robert ^b,f   Upton, Patricia B ^b   Travlos, Gregory S ^c   Swenberg, James A ^a,b  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b University of North Carolina at Chapel Hill   (United States)

^c NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^d NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^e ASTRAZENECA   (United Kingdom)

^f MPI RESEARCH   (United States)

Author keywords

DNA adduct; Forestomach; Hexenal; Mass spectrometry; Proliferating cell nuclear antigen; Rat

Indexed keywords

DNA; HEXOBARBITAL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DISEASE ASSOCIATION; DNA ADDUCT; DNA BINDING; DNA DAMAGE; GASTRITIS; HISTOLOGY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; STOMACH ULCER; TOXICITY;

ADMINISTRATION, ORAL; ALDEHYDES; ANIMALS; BODY WEIGHT; CELL PROLIFERATION; CLINICAL CHEMISTRY TESTS; DEOXYGUANOSINE; DNA; DNA ADDUCTS; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; GASTRITIS; HEMATOLOGIC TESTS; LIPID PEROXIDATION; LIVER; MALE; MUTAGENS; PROLIFERATING CELL NUCLEAR ANTIGEN; RATS; RATS, INBRED F344; STOMACH; TOXICITY TESTS;

RATTUS;

EID: 42149170575     PISSN: 01926233     EISSN: 15331601     Source Type: Journal    
DOI: 10.1177/0192623307311758     Document Type: Article

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