Gamma heavy chain disease in a patient with diabetes and chronic renal insufficiency: Diagnostic assessment of the heavy chain fragment

Journal of Clinical Laboratory Analysis

Volumn 22, Issue 2, 2008, Pages 146-150

  Lee, Maria Teresa ^a   Parwani, Anil ^a   Humphrey, Richard ^a   Hamilton, Robert G ^a   Myers, Donna I ^a   Detrick, Barbara ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

IgG subclass; Kidney disease; Monoclonal gammopathy; Serum immunoglobulin; Urine immunofixation

Indexed keywords

IMMUNOGLOBULIN G; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN HEAVY CHAIN; PLASMA PROTEIN;

ADULT; ARTICLE; CASE REPORT; CHRONIC KIDNEY FAILURE; COMORBIDITY; ELECTROPHORESIS; FEMALE; HEAVY CHAIN DISEASE; HUMAN; IMMUNOGLOBULIN BLOOD LEVEL; NON INSULIN DEPENDENT DIABETES MELLITUS; PROTEIN URINE LEVEL;

BLOOD PROTEINS; DIABETES COMPLICATIONS; FEMALE; HEAVY CHAIN DISEASE; HUMANS; IMMUNOELECTROPHORESIS; IMMUNOGLOBULIN FRAGMENTS; IMMUNOGLOBULIN GAMMA-CHAINS; MIDDLE AGED; RENAL INSUFFICIENCY, CHRONIC; URINALYSIS;

EID: 42149146250     PISSN: 08878013     EISSN: 10982825     Source Type: Journal    
DOI: 10.1002/jcla.20233     Document Type: Article

References (10)

1. Franklin EC, Lowenstein J, Bigelow B, Meltzer M. Heavy chain disease - a new disorder of serum gamma-globulins: report of the first case. Am J Med 1964;37:332-350.
2. Witzig TE, Wahner-Roedler DL. Heavy chain disease. Curr Treat Options Oncol 2002;3:247-254.
3. Fermand JP, Brouet JC. Heavy-chain diseases. Hematol Oncol Clin North Am 1999;13:1281-1294.
4. Wahner-Roedler DL, Witzig TE, Loehrer LL, Kyle RA. Gamma-heavy chain disease: review of 23 cases. Medicine (Baltimore) 2003;82:236-250.
5. Hamilton RG. Human IgG subclass measurements in the clinical laboratory. Clin Chem 1987;33:1707-1725.
6. Fine KD, Stone MJ. Alpha-heavy chain disease, Mediterranean lymphoma, and immunoproliferative small intestinal disease: a review of clinicopathological features, pathogenesis, and differential diagnosis. Am J Gastroenterol 1999;94:1139-1152.
7. Kambham N, Markowitz GS, Appel GB, Kleiner MJ, Aucouturier P, D'Agati VD. Heavy chain deposition disease: the disease spectrum. Am J Kidney Dis 1999;33:954-962.
8. Osserman EF, Takatsuki K. Clinical and immunochemical studies of four cases of heavy (H-gamma-2) chain disease. Am J Med 1964;37:351-373.
9. Soma J, Sato K, Sakuma T, et al. Immunoglobulin gamma3-heavy-chain deposition disease: report of a case and relationship with hypocomplementemia. Am J Kidney Dis 2004;43:E10-E16.
10. Danevad M, Sletten K, Gaarder PI, Mellbye OJ, Husby G. The amino acid sequence of a monoclonal gamma 3-heavy chain from a patient with articular gamma-heavy chain deposition disease. Scand J Immunol 2000;51:602-606.