Prospective cohort study of HIV post-exposure prophylaxis for sexual assault survivors

Antiviral Therapy

Volumn 13, Issue 1, 2008, Pages 87-95

  Loutfy, Mona Rafik ^a,b   Macdonald, Sheila ^c,d   Myhr, Terri ^b   Husson, Heather ^b   Du Mont, Janice ^b,d   Balla, Shannon ^b   Antoniou, Tony ^e   Rachlis, Anita ^a,f  

^a UNIVERSITY OF TORONTO   (Canada)

^b WOMEN S COLLEGE HOSPITAL   (Canada)

^c Ontario Network of Sexual Assault/Domestic Violence Treatment Centres   (Canada)

^d UNIVERSITY OF TORONTO   (Canada)

^e ST MICHAEL'S HOSPITAL   (Canada)

^f SUNNYBROOK RESEARCH INSTITUTE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

LAMIVUDINE PLUS ZIDOVUDINE; LOPINAVIR PLUS RITONAVIR;

ADOLESCENT; ADULT; AGED; ANXIETY; ARTICLE; BLOOD DYSCRASIA; CANADA; CHILD; COHORT ANALYSIS; CONFIDENCE INTERVAL; DIARRHEA; DRUG WITHDRAWAL; FATIGUE; FEMALE; FOLLOW UP; HEADACHE; HEALTH PROGRAM; HIGH RISK POPULATION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INFECTION PREVENTION; INFECTION RISK; MAJOR CLINICAL STUDY; MALE; MOOD CHANGE; MULTIVARIATE LOGISTIC REGRESSION ANALYSIS; NAUSEA; OUTCOME ASSESSMENT; PATIENT ATTITUDE; PATIENT COUNSELING; PREDICTION; PRIORITY JOURNAL; PROSPECTIVE STUDY; RISK REDUCTION; SEXUAL CRIME; SIDE EFFECT; SURVIVOR; SYMPTOM; VOMITING;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANTI-HIV AGENTS; CHILD; CHILD, PRESCHOOL; COHORT STUDIES; DRUG COMBINATIONS; FEMALE; HIV INFECTIONS; HUMANS; LAMIVUDINE; MALE; MIDDLE AGED; ONTARIO; PYRIMIDINONES; RAPE; RISK FACTORS; ZIDOVUDINE;

EID: 42149140530     PISSN: 13596535     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Centers for Disease Control and Prevention (CDC). 2001. Updated US Public Health Service Guidelines for the Management of Occupational Exposures to HBV, HCV and HIV and Recommendations for Postexposure Prophylaxis. MMWR 2001; 50:1-54.
2. Centers for Disease Control and Prevention (CDC). 2005. Updated U.S. Public Health Service Guidelines for the Management of Occupational Exposures to HIV and Recommendations for Postexposure Prophylaxis. MMWR 2005; 54:1-17.
3. Smith DK, Grohskopf LA, Black RJ, et al. Antiretroviral Postexposure Prophylaxis After Sexual, Injection-Drug Use, or Other Non-occupational Exposure to HIV in the United States: Recommendations from the U.S. Department of Health and Human Services. MMWR Recomm Rep 2005; 54(RR-2):1-20.
4. Wiebe ER, Comay SE, McGregor M, Ducceschi S. Offering HIV prophylaxis to people who have been sexually assaulted: 16 months' experience in a sexual assault service. CMAJ 2000; 162:641-645.
5. Myles JE, Hirozawa A, Katz MH, Kimmerling R, Bamberger JD. Post-exposure prophylaxis for HIV after sexual assault. JAMA 2000; 284:1516- 1518.
6. Templeton DJ, Davies SC, Garvin AL, Garsia RJ. The uptake of HIV post-exposure prophylaxis within a sexual assault setting in Sydney, Australia. Int J STD AIDS 2005; 16:108-111.
7. Limb S, Kawsar M, Forster GE. HIV post-exposure prophylaxis after sexual assault: the experience of a sexual assault service in London. Int J STD AIDS 2002; 13:602-605.
8. Neu N, Heffernan-Vacca S, Millery M, Stimell M, Brown J. Postexposure prophylaxis for HIV in children and adolescents after sexual assault: a prospective observational study in an urban medical center. Sex Transm Dis 2007; 34:65-68.
9. Olshen E, Hsu K, Woods ER, Harper M, Harnisch B, Samples CL. Use of human immunodeficiency virus postexposure prophylaxis in adolescent sexual assault victims. Arch Pediatr Adolesc Med 2006; 160:674-680.
10. Garcia MT, Figueiredo RM, Moretti ML, et al. Postexposure prophylaxis after sexual assaults: a prospective cohort study. Sex Transm Dis 2005; 32:214-219.
11. Speight CG, Klufio A, Kilonzo SN, et al. Piloting postexposure prophylaxis in Kenya raises specific concerns for the management of childhood rape. Trans R Soc Trop Med Hyg 2006; 110:14-18.
12. Hachey M, van As AB. HIV postexposure prophylaxis in victims of child sexual abuse. Ann Emerg Med 2005; 46:97-98.
13. New York State Department of Health AIDS Institute (NYSDOH AI). HIV Prophylaxis Following Non-Occupational Exposure Including Sexual Assault. (Updated December 2005. Accessed 8 January 2008.) Available from http://www.hivguidelines.org/GuidelineDocuments/a-npep.pdf
14. Nonoccupational HIV PEP Task Force, Brown University AIDS Program, and the Rhode Island Department of Health. Nonoccupational human immunodeficiency virus post-exposure prophylaxis guidelines for Rhode Island healthcare practitioners, September 2002. (Accessed 8 January 2008.) Available from http://aidsetc.org/pdf/guidelines/ri_npep_glines.pdf
15. Myles JE, Bamberger J. Offering HIV prophylaxis following sexual assault: recommendations for the State of California. 2001. Prepared for the Housing and Urban Health of San Francisco Department of Public Health and the California HIV PEP after Sexual Assault Task Force in conjunction with The California State Office of AIDS. (Accessed 8 January 2008.) Available from http://www.dhs.ca. gov/AIDS/Reports/PDF/HIVProphylaxis FollowingSexualAssault.pdf
16. Massachusetts (Commonwealth of) Department of Public Health. 2005. HIV Prophylaxis Following Non-Occupational Exposures Recommended Protocol Components. (Accessed 8 January 2008.) Available from http://www.mass.gov/? pageID=eohhs2terminal&L=6&L0=Home&Ll=ProviderScL2= Guidelines+and+Resources&L3=Guidelines+for+Clinical+Treatment&L4= Diseases+%26+Conditions&L5=HIV%26%2347%3bAIDS&sid=Eeohhs2&b= terminalcontent&f=dph_aids_p_exposure_nonoccupational&csid=Eeohhs2
17. Roland, M. HIV post-exposure prophylaxis following non-occupational exposures: background paper for WHO consultation. September 3-5, 2005. University of California, San Francisco, San Francisco General Hospital Positive Health (AIDS) Program. (Accessed 8 January 2008) Available from http://hivinsite.ucsf.edu/pdf/p01-kb-new/kbr-07-02-07-roland.pdf
18. European Project on Non-Occupational Post Exposure Prophylaxis (EURO-NONOPEP). April 10, 2002. Management of non-occupational post exposure prophylaxis to HIV (NONPEP): sexual, injection drug user or other exposures. (Accessed 8 January 2008.) Available from http://www.gencat.net/salut/portal/ cat/edrceescat.pdf
19. Carrieri MP, Bendiane MK, Moatti JP, Rey D. Access to HIV prophylaxis for survivors of sexual assault: the tip of the iceberg. Antivir Ther 2006; 11:391-392.
20. Wasserheit JN. Epidemiological synergy: interrelationships between human immunodeficiency virus infection and other sexually transmitted diseases. Sex Transm Dis 1992; 19:61-77.
21. Laga M, Manoka A, Kivuvu M, et al. Non-ulcerative sexually transmitted diseases as risk factors for HIV-1 transmission in women: results from a cohort study. AIDS 1993; 7:95-102.
22. Bamberger JD, Waldo CR, Gerberding L, Katz MK. Postexposure prophylaxis for human immunodeficiency virus (HIV) infection following sexual assault. Am J Med 1999; 106:323-326.
23. Fong C. Post-exposure prophylaxis for HIV infection after sexual assault: when is it indicated? Emerg Med J 2001; 18:242-245.
24. Ontario Network of Sexual Assault/Domestic Violence Treatment Centres. Available at www.satcontario.com/HIVPEP
25. AIDS Clinical Trials Group. Table of grading severity of adult adverse experiences. Rockville, MD, USA: Division of AIDS, National Institute of Allergy and Infectious Diseases 2004.
26. Pinkerton SD, Holtgrave DR, Bloom FR. Cost-effectiveness of post-exposure prophylaxis following sexual exposure to HIV. AIDS 1998; 12:1067-1078.
27. Rabaud C, Burty C, Grandidier M, et al. Tolerability of postexposure prophylaxis with the combination of zidovudine-lamivudine and lopinavir-ritonavir for HIV infection. Clin Infect Dis 2005; 40:303-305.