Determination of curcumol in plasma by HPLC-MS/MS method and its pharmacokinetics in Beagle dogs

Yaoxue Xuebao

Volumn 42, Issue 9, 2007, Pages 973-977

  Zhang, Rui ^a   Wang, Ben Jie ^a   Zhao, Heng Li ^b   Li, Xiao Li ^a   Wei, Chun Min ^a   Guo, Rui Chen ^a  

^a SHANDONG UNIVERSITY   (China)

^b SHANDONG UNIVERSITY   (China)

Author keywords

Curcumol; HPLC MS MS; Pharmacokinetics; Zedoary turmeric oil fat emulsion

Indexed keywords

CURCUMOL; HERBACEOUS AGENT; PLANT EXTRACT; SESQUITERPENE; TURMERIC EXTRACT; VEGETABLE OIL;

ANIMAL; AREA UNDER THE CURVE; ARTICLE; BLOOD; CHEMISTRY; CURCUMA LONGA; DOG; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOLATION AND PURIFICATION; MALE; MEDICINAL PLANT; METHODOLOGY; RANDOMIZATION; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY;

ANIMALS; AREA UNDER CURVE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CURCUMA; DOGS; DRUGS, CHINESE HERBAL; MALE; PLANT EXTRACTS; PLANT OILS; PLANTS, MEDICINAL; RANDOM ALLOCATION; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SESQUITERPENES; TANDEM MASS SPECTROMETRY;

EID: 42149136833     PISSN: 05134870     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (8)

1. Zhao Y, Yang RG, Luo M. Progress in pharmacological action and clinical application of zedoary turmeric oil [J]. Intern Med J Pract Tradit Chin Med Sci, 2006,20:125-126.
2. Xu SY, Bian RL, Chen X. Empirical Method of Pharmacology [M]. 3rd ed. Beijing; People's Health Press, 2002:202-204.
3. Zhang YX. New Introduction to Traditional Chinese Medicine Pharmacology[M]. Beijing- People's Health Press, 2004:42-46.
4. You J, Li QP, Yu YW, et al. Pharmacokinetic studies of zedoary oil by HPLC [J]. Chin Pharm J, 2005,40:380-382.
5. Yang SD, Chen JM, Chen YH. Determination of curcumol in zedoary turmeric oil of Curcumol wenyujin [J]. Acta Pharm Sin, 1979,14-356-360.
6. Tian SJ, Liang WF. Study of zedoary turmeric oil -determination of curcumol and curdione in Curcumol wenyujin with thin-layer scanning method [J]. Chin J Pharm Anal, 1985,5:136-138.
7. Gu XM, Yang Y. Determination of curcumol in zedoary turmeric oil and peppermint oil by vapor phase chromatography [J]. Chin J Pharm Anal, 1982, 2:75-78.
8. 3H-curcumol in normal rats and tumor-bearing mice [J]. Acta Pharm Sin, 1980,15:257-262.