Proteome response in HT-29 human colorectal cancer cells to two apoptosis-inducing compounds with different mode of action

International Journal of Cancer

Volumn 122, Issue 10, 2008, Pages 2223-2232

  Winkelmann, Isabel ^a   Näßl, Anna Maria ^a   Daniel, Hannelore ^a   Wenzel, Uwe ^b,c  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b JUSTUS LIEBIG UNIVERSITY   (Germany)

^c Interdisciplinary Research Center   (Germany)

Author keywords

Apoptosis; HT 29 human colon cancer cells; Mitochondria; Nuclear membrane; Proteome

Indexed keywords

CAMPTOTHECIN; COPROPORPHYRINOGEN OXIDASE; CYTOCHROME; DNA TOPOISOMERASE; FLAVONE; NUCLEAR PROTEIN; PROTEOME; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE; ANTINEOPLASTIC AGENT; FLAVONOID; TUMOR MARKER;

ADAPTATION; APOPTOSIS; ARTICLE; CELL DIVISION; CELL NUCLEUS MEMBRANE; COLORECTAL CANCER; CONTROLLED STUDY; DRUG EXPOSURE; DRUG MECHANISM; HUMAN; HUMAN CELL; MITOCHONDRION; NUCLEOTIDE SEQUENCE; PH; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; RESPIRATORY CHAIN; SYNTHESIS; TWO DIMENSIONAL GEL ELECTROPHORESIS; CELL STRAIN HT29; COMPARATIVE STUDY; DRUG EFFECT; MASS SPECTROMETRY; METABOLISM; PHYSIOLOGY;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CAMPTOTHECIN; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; FLAVONOIDS; HT29 CELLS; HUMANS; PROTEOME; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TUMOR MARKERS, BIOLOGICAL;

EID: 42149127586     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.23387     Document Type: Article

References (39)

1. Pajak B, Orzechowski A. Overview how adenocarcinoma cancer cells avoid immune- and chemotherapy-induced apoptosis. Adv Med Sci 2006;51:39-45.
2. Hengartner MO. The biochemistry of apoptosis. Nature 2000;407:770-6.
3. Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000; 100:57-70.
4. Nicholson DW. ICE/CED3-like proteases as therapeutic targets for the control of inappropriate apoptosis. Nat Biotechnol 1996:14:297-301.
5. Nicholson DW. From bench to clinic with apoptosis-based therapeutic agents. Nature 1996;407,810-16.
6. Legarza K, Yang LX. New molecular mechanisms of action of camptothecin-type drugs. Anticancer Res 2006;26:3301-5.
7. Pommier Y. Topoisomerase I inhibitors: camptothecins and beyond. Nat Rev Cancer 2006;6:789-802.
8. Giles GI, Sharma RP. Topoisomerase enzymes as therapeutic targets for cancer chemotherapy. Med Chem 2005;1:383-94.
9. Wenzel U, Kuntz S, De Sousa UJ, Daniel H. Nitric oxide suppresses apoptosis in human colon cancer cells by scavenging mitochondrial superoxide anions. Int J Cancer 2003;106:666-75.
10. Wenzel U, Kuntz S, Daniel H. Nitric oxide levels in human preneoplastic colonocytes determine their susceptibility toward antineoplastic agents. Mol Pharmacol 2003;64:1494-502.
11. Winkelmann I, Diehl D, Oesterle D, Daniel H, Wenzel U. The suppression of aberrant crypt multiplicity in colonic tissue of 1,2-dimethylhydrazine-treated C57BL/6J mice by dietary flavone is associated with an increased expression of Krebs-cycle enzymes. Carcinogenesis 2007;28:1446-54.
12. Wenzel U, Schobert K, Lohner K, Daniel H. Activation of mitochondrial lactate uptake by flavone induces apoptosis in human colon cancer cells. J Cell Physiol 2005;202:379-90.
13. Rabilloud T. Use of thiourea to increase the solubility of membrane proteins in two-dimensional electrophoresis. Electrophoresis 1998; 19:758-60.
14. Gorg A, Obermaier C, Boguth G, Harder A, Scheibe B, Wildgruber R, Weiss W. The current state of two-dimensional electrophoresis with immobilized pH gradients. Electrophoresis 2000;21:1037-53.
15. Gorg A, Obermaier C, Boguth G, Weiss W. Recent developments in two-dimensional gel electrophoresis with immobilized pH gradients: wide pH gradients up to pH 12, longer separation distances and simplified procedures. Electrophoresis 1999;20:712-17.
16. Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970;227,680-5.
17. Gobom J, Schuerenberg M, Mueller M, Theiss D, Lehrach H, Nordhoff E. Alpha-cyano-4-hydroxycinnamic acid affinity sample preparation. A protocol for MALDI-MS peptide analysis in proteomics. Anal Chem 2001;73:434-8.
18. Schulmann K, Reiser M, Schmiegel W. Colonic cancer and polyps. Best Pract Res Clin Gastroenterol 2002;16:91-114.
19. Brooks GA. Lactate shuttles in nature. Biochem Soc Trans 2002;30:258-64.
20. Gatenby RA. The potential role of transformation-induced metabolic changes in tumor-host interaction. Cancer Res 1995;55:4151-6.
21. Gatenby RA, Gillies RJ. Why do cancers have high aerobic glycolysis? Nat Rev Cancer 2004;4:891-9.
22. Coghlin C, Carpenter B, Dundas SR, Lawrie LC, Telfer C, Murray GI. Characterization and over-expression of chaperonin t-complex proteins in colorectal cancer. J Pathol 2006;210:351-7.
23. Fuchs D, Erhard P, Turner R, Rimbach G, Daniel H, Wenzel U. Genistein reverses changes of the proteome induced by oxidized-LDL in EA.hy 926 human endothelial cells. J Proteome Res 2005;4:369-76.
24. Fuchs D, Erhard P, Rimbach G, Daniel H, Wenzel U. Genistein blocks homocysteine-induced alterations in the proteome of human endothelial cells. Proteomics 2005;5:2808-18.
25. Salinas AE, Wong MG. Glutathione S-transferases - a review. Curr Med Chem 1999;6:279-309.
26. Khalil AA, James P. Biomarker discovery: a proteomic approach for brain cancer profiling. Cancer Sci 2007;98:201-13.
27. Ren Y, Schulz H. Metabolic functions of the two pathways of oleate β-oxidation double bond metabolism during the β-oxidation of oleic acid in rat heart mitochondria. J Biol Chem 2003;278:111-16.
28. Wenzel U, Nickel A, Daniel H. Increased mitochondrial palmitoylcarnitine/carnitine countertransport by flavone causes oxidative stress and apoptosis in colon cancer cells. Cell Mol Life Sci 2005;62:3100-5.
29. Broers JL, Bronnenberg NM, Kuijpers HJ, Schutte B, Hutchison CJ, Ramaekers FC. Partial cleavage of A-type lamins concurs with their total disintegration from the nuclear lamina during apoptosis. Eur J Cell Biol 2002;81:677-91.
30. Radomski N, Jost E. Molecular cloning of a murine cDNA encoding a novel protein, p38-2G4, which varies with the cell cycle. Exp Cell Res 1995;220:434-45.
31. Yuan RH, Jeng YM, Chen HL, Lai PL, Pan HW, Hsieh FJ, Lin CY, Lee PH, Hsu HC. Stathmin overexpression cooperates with p53 mutation and osteopontin overexpression, and is associated with tumour progression, early recurrence, and poor prognosis in hepatocellular carcinoma. J Pathol 2006;209:549-58.
32. Nagata T, Kishi H, Liu QL, Yoshino T, Matsuda T, Jin ZX, Murayama K, Tsukada K, Muraguchi A. Possible involvement of cyclophilin B and caspase-activated deoxyribonuclease in the induction of chromosomal DNA degradation in TCR-stimulated thymocytes. J Immunol 2000;165:4281-9.
33. Schagger H, Pfeiffer K. Supercomplexes in the respiratory chains of yeast and mammalian mitochondria. EMBO J 2000;19:1777-83.
34. Woodard SI, Dailey HA. Multiple regulatory steps in erythroid heme biosynthesis. Arch. Biochem. Biophys. 2000;384:375-8.
35. Welsh SJ, Bellamy WT, Briehl MM, Powis G. The redox protein thioredoxin-1 (Trx-1) increases hypoxia-inducible factor 1α protein expression: Trx-1 overexpression results in increased vascular endothelial growth factor production and enhanced tumor angiogenesis. Cancer Res 2002;62:5089-95.
36. Stewart JJ, White JT, Yan X, Collins S, Drescher CW, Urban ND, Hood L, Lin B. Proteins associated with Cisplatin resistance in ovarian cancer cells identified by quantitative proteomic technology and integrated with mRNA expression levels. Mol Cell Proteomics 2006;5:433-43.
37. Dechat T, Shimi T, Adam SA, Rusinol AE, Andres DA, Spielmann HP, Sinensky MS, Goldman RD. Alterations in mitosis and cell cycle progression caused by a mutant lamin A known to accelerate human aging. Proc Natl Acad Sci USA 2007;104:4955-60.
38. Cavelier G, Amzel LM. Mechanism of NAD(P)H:quinone reductase: ab initio studies of reduced flavin. Proteins 2001;43:420-32.
39. Floryk D, Tollaksen SL, Giometti CS, Huberman E. Differentiation of human prostate cancer PC-3 cells induced by inhibitors of inosine 5′-monophosphate dehydrogenase. Cancer Res 2004;64:9049-56.