Adolescent cholesterol metabolism predicts coronary risk factors at middle age: the Cardiovascular Risk in Young Finns Study

Translational Research

Volumn 151, Issue 5, 2008, Pages 260-266

  Miettinen, Tatu A ^a   Gylling, Helena ^b   Raitakari, Olli T ^c   Hallikainen, Maarit ^d   Viikari, Jorma ^e  

^a UNIVERSITY OF HELSINKI   (Finland)

^b UNIVERSITY OF EASTERN FINLAND   (Finland)

^c KUOPIO UNIVERSITY HOSPITAL   (Finland)

^d UNIVERSITY OF TURKU   (Finland)

^e NONE

Author keywords

[No Author keywords available]

Indexed keywords

HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; STEROL; TRIACYLGLYCEROL;

ADOLESCENT; ADULT; ARTICLE; BODY MASS; CHOLESTEROL METABOLISM; CHOLESTEROL SYNTHESIS; CONTROLLED STUDY; CORONARY RISK; FOLLOW UP; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SCHOOL CHILD; SYSTOLIC BLOOD PRESSURE; TRIACYLGLYCEROL BLOOD LEVEL;

EID: 42149107383     PISSN: 19315244     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.trsl.2008.02.003     Document Type: Article

References (21)

1. Berenson G.S., Srinivasan S.R., Bao W., Newman III W.P., Tracy R.E., and Wattigney W.A. Association between multiple cardiovascular risk factors and atherosclerosis in children and young adults. N Engl J Med 338 (1998) 1650-1656
2. Li S., Chen W., Srinivasan S.R., Bond M.G., Tang R., Urbina E.M., and Berenson G.S. Childhood cardiovascular risk factors and carotid vascular changes in adulthood: the Bogalusa Heart Study. JAMA 290 (2003) 2271-2276
3. Raitakari O.T., Juonala M., Kähönen M., et al. Cardiovascular risk factors in childhood as predictors of carotid artery intima-media thickness in adulthood: the Cardiovascular Risk in Young Finns Study. JAMA 290 (2003) 2277-2283
4. Juonala M., Järvisalo M.J., Mäki-Torkko N., Kähönen M., Viikari J.S.A., and Raitakari O.T. Risk factors identified in childhood and decreased carotid artery elasticity in adulthood. The Cardiovascular Risk in Young Finns Study. Circulation 112 (2005) 1486-1493
5. Johnson H.M., Douglas P.S., Srinivasan S.R., et al. Predictors of carotid intima-media thickness progression in young adults. The Bogalusa Heart Study. Stroke 38 (2007) 900-905
6. Bao W., Srinivasan S.R., Wattigney W.A., and Berenson G.S. Persistence of multiple cardiovascular risk clustering related to syndrome X from childhood to young adulthood: The Bogalusa Heart Study. Arch Intern Med 154 (1994) 1842-1847
7. Raitakari O.T., Juonala M., and Viikari J.S. Obesity in childhood and vascular changes in adulthood: insights into the Cardiovascular Risk in Young Finns Study. Int J Obes (London) 29 Suppl 2 (2005) S101-S104
8. Srinivasan S.R., Frontini M.G., Xu J., and Berenson G.S. Utility of childhood non-high-density lipoprotein cholesterol levels in predicting adult dyslipidemia and other cardiovascular risks: the Bogalusa Heart Study. Pediatrics 118 (2006) 201-206
9. Tzou W.S., Douglas P.S., Srinivasan S.R., et al. Increased subclinical atherosclerosis in young adults with metabolic syndrome: the Bogalusa Heart Study. J Am Coll Cardiol 46 (2005) 457-463
10. Miettinen T.A., Tilvis R.S., and Kesäniemi Y.A. Serum cholestanol and plant sterol levels in relation to cholesterol metabolism in middle-aged men. Metabolism 38 (1989) 136-140
11. Miettinen T.A., Tilvis R.S., and Kesäniemi Y.A. Serum plant sterols and cholesterol precursors reflect cholesterol absorption and synthesis in volunteers of a randomly selected male population. Am J Epidemiol 131 (1990) 20-31
12. Gylling H., and Miettinen T.A. Inheritance of cholesterol metabolism of probands with high or low cholesterol absorption. J Lipid Res 43 (2002) 1472-1476
13. Kesäniemi Y.A., and Miettinen T.A. Cholesterol absorption efficiency regulates plasma cholesterol level in the Finnish population. Eur J Clin Invest 17 (1987) 391-395
14. Miettinen T.A., Gylling H., Viikari J., Lehtimäki T., and Raitakari O.T. Synthesis and absorption of cholesterol in Finnish boys by serum non-cholesterol sterols. THE CARDIOVASCULAR RISK IN YOUNG FINNS STUDY. Atherosclerosis (2008) Jan 4 [Epub ahead of print].
15. Åkerblom H.K., Viikari J., Uhari M., et al. Atherosclerosis precursors in Finnish children and adolescents. I. General description of the cross-sectional study of 1980, and an account of the children's and families' state of health. Acta Pediatr Scand 318 Suppl (1985) 49-63
16. Friedewald W.T., Levy R.I., and Fredrickson D.S. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 18 (1972) 499-502
17. Porkka K.V., Raitakari O.T., Leino A., et al. Trends in serum lipid levels during 1980-1992 in children and young adults. The Cardiovascular Risk in Young Finns Study. Am J Epidemiol 146 (1997) 64-77
18. Miettinen T.A. Cholesterol metabolism during ketoconazole treatment in man. J Lipid Res 29 (1988) 43-51
19. Miettinen T.A., and Gylling H. Cholesterol absorption efficiency and sterol metabolism in obesity. Atherosclerosis 153 (2000) 241-248
20. Viikari J., Åkerblom H.K., Nikkari T., et al. Atherosclerosis precursors in Finnish children and adolescents. IV. Serum lipids in newborns, children and adolescents. Acta Paediatr Scand 318 Suppl (1985) 127-133
21. Juonala M., Viikari J.S., Hutri-Kähönen N., et al. The 21-year follow-up of the Cardiovascular Risk in Young Finns Study: risk factor levels, secular trends and east-west difference. J Intern Med 255 (2004) 457-468