Fractional allelic imbalance could allow for the development of an equitable transplant selection policy for patients with hepatocellular carcinoma

Liver Transplantation

Volumn 14, Issue 4, 2008, Pages 443-450

  Dvorchik, Igor ^a,d   Schwartz, Myron ^b   Fiel, M Isabel ^b   Finkelstein, Sydney D ^c   Marsh, J Wallis ^a  

^a UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^b MOUNT SINAI MEDICAL CENTER   (United States)

^c RedPath Integrated Pathology   (United States)

^d UNIVERSITY OF PITTSBURGH GRADUATE SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ADULT; AGED; ALLELE; ARTICLE; CANCER CLASSIFICATION; CANCER INVASION; CANCER STAGING; CONTROLLED STUDY; FEMALE; FRACTIONAL ALLELIC IMBALANCE; GENE LOSS; GENETIC ANALYSIS; GENETIC MARKER; HEALTH CARE POLICY; HUMAN; HUMAN TISSUE; LIVER CELL CARCINOMA; LIVER TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; MICRODISSECTION; MUTATIONAL ANALYSIS; PATIENT SELECTION; PRIORITY JOURNAL; PROGNOSIS; RECURRENT CANCER; TUMOR GROWTH;

ADOLESCENT; ADULT; AGED; ALLELIC IMBALANCE; CARCINOMA, HEPATOCELLULAR; HUMANS; LIVER NEOPLASMS; LIVER TRANSPLANTATION; MICROSATELLITE REPEATS; MIDDLE AGED; NEOPLASM INVASIVENESS; NEOPLASM STAGING; PATIENT SELECTION;

EID: 42149095913     PISSN: 15276465     EISSN: 15276473     Source Type: Journal    
DOI: 10.1002/lt.21393     Document Type: Article

References (15)

1. Mazzaferro V, Regalia E, Doci R, Andreola S, Pulvirenti A, Bozzetti F, et al. Liver transplantation for the treatment of small hepatocellular carcinomas in patients with cirrhosis. New Engl J Med 1996;334:693-699.
2. Roberts JP. Role of adult living liver donation in patients with hepatocellular cancer. Liver Transpl 2003;9:S60-S63.
3. Gondolesi G, Munoz I, Matsumoto C, Fishbein T, Sheiner P, Emre S, et al. Hepatocellular carcinoma: a prime indication for living donor liver transplantation. J Gastrointest Surg 2002;6:102-107.
4. Kaihara S, Kiuchi T, Ueda M, Oike F, Fujimoto Y, Ogawa K, et al. Living donor liver transplantation for hepatocellular carcinoma. Transplantation 2003;75(Suppl): S37-S40.
5. Steinmuller T, Pascher A, Sauer I, Theruvath T, Muller A, Settmacher U, Neuhaus P. Living-donation liver transplantation for hepatocellular carcinoma: time to drop the limitation? Transplant Proc 2002;34:2263-2264.
6. Yao FY, Kinkhabwala M, LaBerge JM, Bass NM, Brown R Jr, Kerlan R et al. The impact of pre-operative loco-regional therapy on outcome after liver transplantation for hepatocellular carcinoma. Am J Transplant 2005;5(Pt 1):795-804.
7. Yao FY, Bass NM, Nikolai B, Merriman R, Davern TJ, Kerlan R, et al. A follow-up analysis of the pattern and predictors of dropout from the waiting list for liver transplantation in patients with hepatocellular carcinoma: implications for the current organ allocation policy. Liver Transpl 2003;9:684-692.
8. Marsh JW, Dvorchik I, Bonham CA, Iwatsuki S. Is the pathologic TNM staging system for patients with hepatoma predictive of outcome? Cancer 2000;88:538-543.
9. Yao FY, Ferrell L, Bass NM, Bacchetti P, Ascher NL, Roberts JP. Liver transplantation for hepatocellular carcinoma: comparison of the proposed UCSF criteria with the Milan criteria and the Pittsburgh modified TNM criteria., Liver Transpl 2002;8:765-774.
10. Llovet JM, Bruix J, Fuster J, Castells A, Garcia-Valdecasas JC, Grande L, et al. Liver transplantation for small hepatocellular carcinoma: the tumor-node-metastasis classification does not have prognostic power. Hepatology 1998;27:1572-1577.
11. Marsh JW, Finkelstein SD, Demetris AJ, Swalsky PA, Sasatomi E, Bandos A, et al. Genotyping of hepatocellular carcinoma in liver transplant recipients adds predictive power for determining recurrence-free survival, Liver Transpl 2003;9:664-671.
12. Finkelstein SD, Marsh W, Demetris AJ, Swalsky PA, Sasatomi E, Bonham A, et al. Microdissection-based allelotyping discriminates de novo tumor from intrahepatic spread in hepatocellular carcinoma, Hepatology 2003;37: 871-879.
13. Smith EH. Complications of percutaneous abdominal fine-needle biopsy. Rev Radiol 1991; 178:253-258.
14. Schotman SN, De Man RA, Stoker J, Zondervan PE, Ijzermans JN. Subcutaneous seeding of hepatocellular carcinoma after percutaneous needle biopsy. Gut 1999;45:626-627.
15. Huang GT, Sheu JC, Yang PM, Lee HS, Wang TH, Chen DS. Ultrasound-guided cutting biopsy for the diagnosis of hepatocellular carcinoma-a study based on 420 patients. J Hepatol 1996;25:334-338.