A whey-protein supplement increases fat loss and spares lean muscle in obese subjects: A randomized human clinical study

Nutrition and Metabolism

Volumn 5, Issue 1, 2008, Pages

  Frestedt, Joy L ^a   Zenk, John L ^a   Kuskowski, Michael A ^b   Ward, Loren S ^c   Bastian, Eric D ^c  

^a Minnesota Applied Research Center   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c Glanbia Innovation Centre   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; FAT; LEUCINE;

ADULT; ANALYSIS OF COVARIANCE; ANTHROPOMETRY; ARTICLE; BEVERAGE; BIOLOGICAL ACTIVITY; BLOOD SAMPLING; BODY FAT; BODY WEIGHT; CALORIC INTAKE; CLINICAL STUDY; CONTROL GROUP; CONTROLLED STUDY; DIET SUPPLEMENTATION; DUAL ENERGY X RAY ABSORPTIOMETRY; EVALUATION; HUMAN; LEAN BODY WEIGHT; MAJOR CLINICAL STUDY; MILK; OBESITY; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; STUDENT T TEST; SUPPLEMENTATION; WEIGHT REDUCTION; WHEY;

EID: 42049123844     PISSN: None     EISSN: 17437075     Source Type: Journal    
DOI: 10.1186/1743-7075-5-8     Document Type: Article

References (30)

1. Curbing the obesity epidemic. Editorial, The Lancet 2006 367 1549 10.1016/S0140-6736(06)68664-9
2. Relationship of obesity and visceral adiposity with serum concentrations of CRP, TNF-alpha and IL-6. HS Park JY Park R Yu, Diabetes Res Clin Pract 2005 69 29 35 10.1016/j.diabres.2004.11.007 15955385
3. Medical consequences of obesity. GA Bray, J Clin Endocrinol Metab 2004 89 2583 2589 10.1210/jc.2004-0535 15181027
4. Effects of variation in protein and carbohydrate intake on body mass and composition during energy restriction: a meta-regression 1. JW Krieger HS Sitren MJ Daniels B Langkamp-Henken, Am J Clin Nutr 2006 83 260 274 16469983
5. A reduced ratio of dietary carbohydrate to protein improves body composition and blood lipid profiles during weight loss in adult women. DK Layman RA Boileau DJ Erickson JE Painter H Shiue C Sather DD Christou, J Nutr 2003 133 411 417 12566476
6. Dietary protein impact on glycemic control during weight loss. DK Layman JI Baum, J Nutr 2004 134 968S 73S. 15051856
7. Effect of an energy-restricted, high-protein, low-fat diet relative to a conventional high-carbohydrate, low-fat diet on weight loss, body composition, nutritional status, and markers of cardiovascular health in obese women. M Noakes JB Keogh PR Foster PM Clifton, Am J Clin Nutr 2005 81 1298 1306 15941879
8. Randomized trial on protein vs carbohydrate in ad libitum fat reduced diet for the treatment of obesity. AR Skov S Toubro B Ronn L Holm A Astrup, Int J Obes Relat Metab Disord 1999 23 528 536 10.1038/sj.ijo.0800867 10375057
9. The underappreciated role of muscle in health and disease. RR Wolfe, Am J Clin Nutr 2006 84 475 482 16960159
10. The role of leucine in weight loss diets and glucose homeostasis. DK Layman, J Nutr 2003 133 261S 267S. 12514305
11. Slow and fast dietary proteins differently modulate postprandial protein accretion. Y Boirie M Dangin P Gachon MP Vasson JL Maubois B Beaufrere, Proc Natl Acad Sci U S A 1997 94 14930 14935 9405716 10.1073/pnas.94.26.14930
12. Relation of nutrients and hormones in polycystic ovary syndrome. SE Kasim-Karakas WM Cunningham A Tsodikov, Am J Clin Nutr 2007 85 688 694 17344488
13. Calcium and dairy acceleration of weight and fat loss during energy restriction in obese adults. MB Zemel W Thompson A Milstead K Morris P Campbell, Obes Res 2004 12 582 590 15090625
14. Regulation of adiposity by dietary calcium. MB Zemel H Shi B Greer D Dirienzo PC Zemel, FASEB Journal 2000 14 1132 1138 10834935
15. Effects of calcium and dairy on body composition and weight loss in African-American adults. MB Zemel J Richards A Milstead P Campbell, Obes Res 2005 13 1218 1225 16076991
16. Calcium and dairy modulation of obesity risk. MB Zemel, Obes Res 2005 13 192 193 15761181
17. The role of dairy foods in weight management. MB Zemel, J Am Coll Nutr 2005 24 537S 46S. 16373953
18. Mechanisms of dairy modulation of adiposity. MB Zemel, J Nutr 2003 133 252S 256S. 12514303
19. Role of calcium and dairy products in energy partitioning and weight management. MB Zemel, Am J Clin Nutr 2004 79 907S 912S. 15113738
20. Dairy augmentation of total and central fat loss in obese subjects. MB Zemel J Richards S Mathis A Milstead L Gebhardt E Silva, Int J Obes Relat Metab Disord 2005 29 391 397 10.1038/sj.ijo.0802880
21. Calcium supplementation of chocolate: effect on cocoa butter digestibility and blood lipids in humans. Y Shahkhalili C Murset I Meirim E Duruz S Guinchard C Cavadini K Acheson, Am J Clin Nutr 2001 73 246 252 11157320
22. Effect of short-term high dietary calcium intake on 24-h energy expenditure, fat oxidation, and fecal fat excretion. R Jacobsen JK Lorenzen S Toubro I Krog-Mikkelsen A Astrup, Int J Obes Relat Metab Disord 2005 29 3 292 301 10.1038/sj.ijo.0802785 15672116
23. Bone minerals changes in obese women during a moderate weight loss with and without calcium supplementation. LB Jensen, J Bone Min Res 2001 16 141 147 10.1359/jbmr.2001.16.1.141
24. A high dairy protein, high-calcium diet minimizes bone turnover in overweight adults during weight loss. J Bowen M Noakes PM Clifton, J Nutr 2004 134 568 573 14988448
25. Intentional and unintentional weight loss increase bone loss and hip fracture risk in older women. KE Ensrud SK Ewing KL Stone JA Cauley PJ Bowman SR Cummings, J Am Geriatr Soc 2003 51 1740 1747 10.1046/j.1532-5415.2003.51558.x 14687352
26. Diet and blood pressure: The paradigm shift. DA McCarron, Science 1998 281 933 934 10.1126/science.281.5379.933 9722467
27. Dairy food consumption, blood pressure and stroke. LK Massey, J Nutr 2001 131 1875 1878 11435500
28. AHA Dietary Guidelines: revision 2000: A statement for healthcare professionals from the Nutrition Committee of the American Heart Association. RM Krauss RH Eckel B Howard LJ Appel SR Daniels RJ Deckelbaum JW Erdman P Kris-Etherton IJ Goldberg TA Kotchen AH Lichtenstein WE Mitch R Mullis K Robinson J Wylie-Rosett S St Jeor J Suttie DL Tribble TL Bazzarre, Circulation 2000 102 2284 2299 11056107
29. Carbohydrate analysis. NH Low, Introduction to the chemical analysis of foods Boston, MA, Jones and Bartlett Publishers, Nielsen SS, 1994 144
30. Popular diets: a scientific review. MR Freedman J King E Kennedy, Obes Res 2001 9 Suppl 1 1S 40S 11346661