-
1
-
-
0020958077
-
Phase I study of 4-demethoxydaunorubicin
-
Bonfante, V., Ferrari, L., Villani, F. and Bonadonna, G. (1983) Phase I study of 4-demethoxydaunorubicin. Invest New Drugs, 1, pp. 161-168.
-
(1983)
Invest New Drugs
, vol.1
, pp. 161-168
-
-
Bonfante, V.1
Ferrari, L.2
Villani, F.3
Bonadonna, G.4
-
2
-
-
0026586008
-
Cytarabine plus IDA or daunorubicin as induction and consolidation therapy for previously untreated adult patients with acute myeloid leukemia
-
Wiernik, P. H., Banks, P. L., Case Jr, D. C., Arlin, Z. A., Periman, P. O. and Todd, M. B. (1992) Cytarabine plus IDA or daunorubicin as induction and consolidation therapy for previously untreated adult patients with acute myeloid leukemia. Blood, 79, pp. 313-319.
-
(1992)
Blood
, vol.79
, pp. 313-319
-
-
Wiernik, P.H.1
Banks, P.L.2
Case Jr., D.C.3
Arlin, Z.A.4
Periman, P.O.5
Todd, M.B.6
-
3
-
-
0025907179
-
Results of a randomized trial comparing IDA and cytosine arabinoside with daunorubicin and cytosine arabinoside in adult patients with newly diagnosed acute myelogenous leukemia
-
Berman, E., Heller, G., Santorsa, J., McKenzie, S., Gee, T. and Kempin, S. (1991) Results of a randomized trial comparing IDA and cytosine arabinoside with daunorubicin and cytosine arabinoside in adult patients with newly diagnosed acute myelogenous leukemia. Blood, 77, pp. 1666-1674.
-
(1991)
Blood
, vol.77
, pp. 1666-1674
-
-
Berman, E.1
Heller, G.2
Santorsa, J.3
McKenzie, S.4
Gee, T.5
Kempin, S.6
-
4
-
-
0026650021
-
A phase III trial comparing idarubicin and daunorubicin in combination with cytarabine in acute myelogenous leukemia: A Southeastern Cancer Study Group Study
-
Vogler, W. R., Velez-Garcia, E., Weiner, R. S., Flaum, M. A., Bartolucci, A. A. and Omura, G. A. (1992) A phase III trial comparing idarubicin and daunorubicin in combination with cytarabine in acute myelogenous leukemia: A Southeastern Cancer Study Group Study. J Clin Oncol, 10, pp. 1103-1111.
-
(1992)
J Clin Oncol
, vol.10
, pp. 1103-1111
-
-
Vogler, W.R.1
Velez-Garcia, E.2
Weiner, R.S.3
Flaum, M.A.4
Bartolucci, A.A.5
Omura, G.A.6
-
5
-
-
0018192615
-
Comparative mammalian metabolism of adriamycin and daunorubicin
-
Lovless, H., Arena, E., Felsted, R. L. and Bachur, N. R. (1978) Comparative mammalian metabolism of adriamycin and daunorubicin. Cancer Res, 38, pp. 593-598.
-
(1978)
Cancer Res
, vol.38
, pp. 593-598
-
-
Lovless, H.1
Arena, E.2
Felsted, R.L.3
Bachur, N.R.4
-
6
-
-
0020348768
-
Human liver daunorubicin reductases
-
Felsted, R. L. and Bachur, N. R. (1982) Human liver daunorubicin reductases. Prog Clin Biol Res, 114, pp. 291-305.
-
(1982)
Prog Clin Biol Res
, vol.114
, pp. 291-305
-
-
Felsted, R.L.1
Bachur, N.R.2
-
7
-
-
0023768323
-
Human carbonyl reductase. Nucleotide sequence analysis of a cDNA and amino acid sequence of the encoded protein
-
Wermuth, B., Bohren, K. M., Heinemann, G., von Wartburg, J. P. and Gabbay, K. H. (1988) Human carbonyl reductase. Nucleotide sequence analysis of a cDNA and amino acid sequence of the encoded protein. J Biol Chem, 263, pp. 16185-16188.
-
(1988)
J Biol Chem
, vol.263
, pp. 16185-16188
-
-
Wermuth, B.1
Bohren, K.M.2
Heinemann, G.3
von Wartburg, J.P.4
Gabbay, K.H.5
-
8
-
-
0024333867
-
The aldo-keto reductase superfamily. cDNAs and deduced amino acid sequences of human aldehyde and aldose reductases
-
Bohren, K. M., Bullock, B., Wermuth, B. and Gabbay, K. H. (1989) The aldo-keto reductase superfamily. cDNAs and deduced amino acid sequences of human aldehyde and aldose reductases. J Biol Chem, 264, pp. 9547-9551.
-
(1989)
J Biol Chem
, vol.264
, pp. 9547-9551
-
-
Bohren, K.M.1
Bullock, B.2
Wermuth, B.3
Gabbay, K.H.4
-
9
-
-
0026476532
-
Immunohistochemical localization of carbonyl reductase in human tissues
-
Wirth, H. and Wermuth, B. (1992) Immunohistochemical localization of carbonyl reductase in human tissues. J Histochem Cytochem, 40, pp. 1857-1863.
-
(1992)
J Histochem Cytochem
, vol.40
, pp. 1857-1863
-
-
Wirth, H.1
Wermuth, B.2
-
11
-
-
0026576715
-
Anthracyclines and their C-13 alcohol metabolites: Growth inhibition and DNA damage following incubation with human tumor cells in culture
-
Kuffel, M. J., Reid, J. M. and Ames, M. M. (1992) Anthracyclines and their C-13 alcohol metabolites: Growth inhibition and DNA damage following incubation with human tumor cells in culture. Cancer Chemother Pharmacol, 30, pp. 51-57.
-
(1992)
Cancer Chemother Pharmacol
, vol.30
, pp. 51-57
-
-
Kuffel, M.J.1
Reid, J.M.2
Ames, M.M.3
-
12
-
-
0023684933
-
Different cytotoxicity and metabolism of doxorubicin, daunorubicin, epirubicin, esorubicin and idarubicin in cultured human and rat hepatocytes
-
Bot, M A Le, Begue, J. M., Kernaleguen, D., Robert, J., Ratanasavanh, D. and Airiau, J. (1988) Different cytotoxicity and metabolism of doxorubicin, daunorubicin, epirubicin, esorubicin and idarubicin in cultured human and rat hepatocytes. Biochem Pharmacol, 37, pp. 3877-3887.
-
(1988)
Biochem Pharmacol
, vol.37
, pp. 3877-3887
-
-
Le Bot, M.A.1
Begue, J.M.2
Kernaleguen, D.3
Robert, J.4
Ratanasavanh, D.5
Airiau, J.6
-
13
-
-
0028843727
-
Protection against daunorubicin cytotoxicity by expression of a cloned human carbonyl reductase cDNA in K562 leukemia cells
-
Gonzalez, B., Akman, S., Doroshow, J., Rivera, H., Kaplan, W. D. and Forrest, G. L. (1995) Protection against daunorubicin cytotoxicity by expression of a cloned human carbonyl reductase cDNA in K562 leukemia cells. Cancer Res, 55, pp. 4646-4650.
-
(1995)
Cancer Res
, vol.55
, pp. 4646-4650
-
-
Gonzalez, B.1
Akman, S.2
Doroshow, J.3
Rivera, H.4
Kaplan, W.D.5
Forrest, G.L.6
-
14
-
-
0030070454
-
Induction of daunorubicin carbonyl reducing enzymes by daunorubicin in sensitive and resistant pancreas carcinoma cells
-
Soldan, M., Netter, K. J. and Maser, E. (1996) Induction of daunorubicin carbonyl reducing enzymes by daunorubicin in sensitive and resistant pancreas carcinoma cells. Biochem Pharmacol, 51, pp. 117-123.
-
(1996)
Biochem Pharmacol
, vol.51
, pp. 117-123
-
-
Soldan, M.1
Netter, K.J.2
Maser, E.3
-
15
-
-
0033988708
-
Development of daunorubicin resistance in tumour cells by induction of carbonyl reduction
-
Ax, W., Soldan, M., Koch, L. and Maser, E. (2000) Development of daunorubicin resistance in tumour cells by induction of carbonyl reduction. Biochem Pharmacol, 59, pp. 293-300.
-
(2000)
Biochem Pharmacol
, vol.59
, pp. 293-300
-
-
Ax, W.1
Soldan, M.2
Koch, L.3
Maser, E.4
-
16
-
-
0028940571
-
Acute induction of adriamycin-resistance in human colon carcinoma HT-29 cells exposed to a sublethal dose of adriamycin
-
Tomida, A., Naito, M. and Tsuruo, T. (1995) Acute induction of adriamycin-resistance in human colon carcinoma HT-29 cells exposed to a sublethal dose of adriamycin. Cancer Sci, 86, pp. 224-232.
-
(1995)
Cancer Sci
, vol.86
, pp. 224-232
-
-
Tomida, A.1
Naito, M.2
Tsuruo, T.3
-
17
-
-
0028224534
-
Cell biological mechanisms of multidrug resistance in tumors
-
Simon, S. M. and Schindler, M. (1994) Cell biological mechanisms of multidrug resistance in tumors. Proc Natl Acad Sci USA, 2691, pp. 3497-3504.
-
(1994)
Proc Natl Acad Sci USA
, vol.2691
, pp. 3497-3504
-
-
Simon, S.M.1
Schindler, M.2
-
18
-
-
0028675262
-
Cellular resistance to cancer chemotherapy
-
Skovsgaard, T., Nielsen, D., Maare, C. and Wassermann, K. (1994) Cellular resistance to cancer chemotherapy. Int Rev Cytol, 156, pp. 77-157.
-
(1994)
Int Rev Cytol
, vol.156
, pp. 77-157
-
-
Skovsgaard, T.1
Nielsen, D.2
Maare, C.3
Wassermann, K.4
-
19
-
-
0027095653
-
Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line
-
Cole, S. P., Bhardwaj, G., Gerlach, J. H., Mackie, J. E., Grant, C. E. and Almquist, K. C. (1992) Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line. Science, 258, pp. 1650-1654.
-
(1992)
Science
, vol.258
, pp. 1650-1654
-
-
Cole, S.P.1
Bhardwaj, G.2
Gerlach, J.H.3
Mackie, J.E.4
Grant, C.E.5
Almquist, K.C.6
-
20
-
-
0027466646
-
Overexpression of a M(r) 110,000 vesicular protein in non-P-glycoprotein-mediated multidrug resistance
-
Scheper, R. J., Broxterman, H. J., Scheffer, G. L., Kaaijk, P., Dalton, W. S. and van Heijningen, T. H. (1993) Overexpression of a M(r) 110,000 vesicular protein in non-P-glycoprotein-mediated multidrug resistance. Cancer Res, 53, pp. 1475-1479.
-
(1993)
Cancer Res
, vol.53
, pp. 1475-1479
-
-
Scheper, R.J.1
Broxterman, H.J.2
Scheffer, G.L.3
Kaaijk, P.4
Dalton, W.S.5
van Heijningen, T.H.6
-
21
-
-
0028574352
-
Influence of idarubicinol on the antileukemic effect of idarubicin
-
Fukushima, T., Kawai, Y., Urasaki, Y., Yoshida, A., Ueda, T. and Nakamura, T. (1994) Influence of idarubicinol on the antileukemic effect of idarubicin. Leuk Res, 18, pp. 943-947.
-
(1994)
Leuk Res
, vol.18
, pp. 943-947
-
-
Fukushima, T.1
Kawai, Y.2
Urasaki, Y.3
Yoshida, A.4
Ueda, T.5
Nakamura, T.6
-
22
-
-
0023581669
-
Pharmacokinetic study of intravenous and oral idarubicin in cancer patients
-
Tamassia, V., Pacciarini, M. A., Moro, E., Piazza, E., Vago, G. and Libretti, A. (1987) Pharmacokinetic study of intravenous and oral idarubicin in cancer patients. Int J Clin Pharmacol Res, 7, pp. 419-426.
-
(1987)
Int J Clin Pharmacol Res
, vol.7
, pp. 419-426
-
-
Tamassia, V.1
Pacciarini, M.A.2
Moro, E.3
Piazza, E.4
Vago, G.5
Libretti, A.6
-
23
-
-
0027470227
-
Clinical pharmacokinetics of idarubicin
-
Robert, J. (1993) Clinical pharmacokinetics of idarubicin. Clin Pharmacokinet, 24, pp. 275-288.
-
(1993)
Clin Pharmacokinet
, vol.24
, pp. 275-288
-
-
Robert, J.1
-
24
-
-
0035488468
-
A pharmacokinetic study of idarubicin in Japanese patients with malignant lymphoma: Relationship with leukocytopenia and neutropenia
-
Fukushima, T., Yamashita, T., Goto, N., Ueda, T., Okabe, K. I. and Kuraishi, Y. (2001) A pharmacokinetic study of idarubicin in Japanese patients with malignant lymphoma: Relationship with leukocytopenia and neutropenia. Int J Hematol, 74, pp. 297-302.
-
(2001)
Int J Hematol
, vol.74
, pp. 297-302
-
-
Fukushima, T.1
Yamashita, T.2
Goto, N.3
Ueda, T.4
Okabe, K.I.5
Kuraishi, Y.6
-
25
-
-
0014533113
-
Fluorometric determination of serum levels and urinary excretion of daunomycin (NSC-82151) in mice and rats
-
Finkel, J. M., Knapp, K. T. and Mulligan, L. T. (1969) Fluorometric determination of serum levels and urinary excretion of daunomycin (NSC-82151) in mice and rats. Cancer Chemother Rep, 53, pp. 159-164.
-
(1969)
Cancer Chemother Rep
, vol.53
, pp. 159-164
-
-
Finkel, J.M.1
Knapp, K.T.2
Mulligan, L.T.3
-
26
-
-
0028894549
-
Studies on the quantitative autoradiography. I. Radioluminography for quantitative autoradiography of 14C
-
Motoji, N., Hayama, E. and Shigematsu, A. (1995) Studies on the quantitative autoradiography. I. Radioluminography for quantitative autoradiography of 14C. Biol Pharm Bull, 18, pp. 89-93.
-
(1995)
Biol Pharm Bull
, vol.18
, pp. 89-93
-
-
Motoji, N.1
Hayama, E.2
Shigematsu, A.3
-
27
-
-
0021102196
-
High-performance liquid chromatographic method for pharmacokinetic studies on the new anthracycline 4-demethoxydaunorubicin and its 13-dihydro derivative
-
Moro, E., Bellotti, V., Jannuzzo, M. G., Stegnjaich, S. and Valzelli, G. (1983) High-performance liquid chromatographic method for pharmacokinetic studies on the new anthracycline 4-demethoxydaunorubicin and its 13-dihydro derivative. J Chromatogr, 274, pp. 281-287.
-
(1983)
J Chromatogr
, vol.274
, pp. 281-287
-
-
Moro, E.1
Bellotti, V.2
Jannuzzo, M.G.3
Stegnjaich, S.4
Valzelli, G.5
-
28
-
-
0026634126
-
High-performance liquid chromatographic analysis of idarubicin and fluorescent metabolites in biological fluids
-
Camaggi, C. M., Carisi, P., Strocchi, E. and Pannuti, F. (1992) High-performance liquid chromatographic analysis of idarubicin and fluorescent metabolites in biological fluids. Cancer Chemother Pharmacol, 30, pp. 303-306.
-
(1992)
Cancer Chemother Pharmacol
, vol.30
, pp. 303-306
-
-
Camaggi, C.M.1
Carisi, P.2
Strocchi, E.3
Pannuti, F.4
-
29
-
-
71849104860
-
Protein measurement with the folin phenol reagent
-
Lowry, O. H., Rosebrough, N. J., Farr, A. L. and Randall, R. J. (1951) Protein measurement with the folin phenol reagent. J Biol Chem, 193, pp. 265-275.
-
(1951)
J Biol Chem
, vol.193
, pp. 265-275
-
-
Lowry, O.H.1
Rosebrough, N.J.2
Farr, A.L.3
Randall, R.J.4
-
30
-
-
0037377917
-
Modeling the metabolism of idarubicin to idarubicinol in rat heart: Effect of rutin and phenobarbital
-
Kang, W. and Weiss, M. (2003) Modeling the metabolism of idarubicin to idarubicinol in rat heart: Effect of rutin and phenobarbital. Drug Metab Dispos, 31, pp. 462-468.
-
(2003)
Drug Metab Dispos
, vol.31
, pp. 462-468
-
-
Kang, W.1
Weiss, M.2
-
31
-
-
0027200184
-
Action mechanism of idarubicin (4-demethoxydaunorubicin) as compared with daunorubicin in leukemic cells
-
Fukushima, T., Ueda, T., Uchida, M. and Nakamura, T. (1993) Action mechanism of idarubicin (4-demethoxydaunorubicin) as compared with daunorubicin in leukemic cells. Int J Hematol, 57, pp. 121-130.
-
(1993)
Int J Hematol
, vol.57
, pp. 121-130
-
-
Fukushima, T.1
Ueda, T.2
Uchida, M.3
Nakamura, T.4
|