PET image denoising using a synergistic multiresolution analysis of structural (MRI/CT) and functional datasets

Journal of Nuclear Medicine

Volumn 49, Issue 4, 2008, Pages 657-666

  Turkheimer, Federico E ^a,b   Boussion, Nicolas ^c   Anderson, Alexander N ^b   Pavese, Nicola ^b   Piccini, Paola ^a,b   Visvikis, Dimitris ^c  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b HAMMERSMITH HOSPITAL   (United Kingdom)

^c CHU MORVAN   (France)

Author keywords

Denoising; Fusion; Multimodality; PET; PET CT; PET MRI; Sensitivity; Synergistic; Wavelets

Indexed keywords

N SEC BUTYL 1 (2 CHLOROPHENYL) N METHYL 3 ISOQUINOLINECARBOXAMIDE C 11; TRACER; UNCLASSIFIED DRUG;

ALGORITHM; ARTICLE; BRAIN FUNCTION; COMPUTER ASSISTED TOMOGRAPHY; COMPUTER SIMULATION; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HUMAN; HUMAN EXPERIMENT; HUNTINGTON CHOREA; IMAGE QUALITY; ISOTOPE LABELING; MICROGLIA; NEUROANATOMY; NEUROIMAGING; NUCLEAR MAGNETIC RESONANCE IMAGING; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RADIOACTIVITY; SIGNAL NOISE RATIO; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; UNCERTAINTY;

CARBON RADIOISOTOPES; DATABASES AS TOPIC; FLUORODEOXYGLUCOSE F18; HUMANS; ISOQUINOLINES; MAGNETIC RESONANCE IMAGING; POSITRON-EMISSION TOMOGRAPHY; TOMOGRAPHY, X-RAY COMPUTED;

EID: 42049112567     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: 10.2967/jnumed.107.041871     Document Type: Article

References (28)

1. Cherry SR. Of mice and men (and positrons): Advances in PET imaging technology. J Nucl Med. 2006;47:1735-1745.
2. Cherry SR, Dahlbom M, Hoffman EJ. 3D PET using a conventional multislice tomograph without septa. J Comput Assist Tomogr. 1991;15:655-668.
3. Melcher CL, Schweitzer JS. Cerium-doped lutetium oxyorthosilicate: a fast, efficient new scintillator. IEEE Trans Nucl Sci. 1992;39:502-505.
4. Turkheimer FE, Banati RB, Visvikis D, Aston JA, Gunn RN, Cunningham VJ. Modeling dynamic PET-SPECT studies in the wavelet domain. J Cereb Blood Flow Metab. 2000;20:879-893.
5. Turkheimer FE, Brett M, Visvikis D, Cunningham VJ. Multiresolution analysis of emission tomography images in the wavelet domain. J Cereb Blood Flow Metab. 1999;19:1189-1208.
6. Turkheimer FE, Brett M, Aston JA, et al. Statistical modeling of positron emission tomography images in wavelet space. J Cereb Blood Flow Metab. 2000;20:1610-1618.
7. Alpert NM, Reilhac A, Chio TC, Selesnick I. Optimization of dynamic measurement of receptor kinetics by wavelet denoising. Neuroimage. 2006;30:444-451.
8. Mallat SG. A theory of multiresolution signal decomposition: the wavelet representation. IEEE Trans Pattern Anal Mach Intell. 1989;11:673-693.
9. Turkheimer FE, Aston JA, Asselin MC, Hinz R. Multi-resolution Bayesian regression in PET dynamic studies using wavelets. Neuroimage. 2006;32:111-121.
10. Boussion N, Hatt M, Lamare F, et al. A multiresolution image based approach for correction of partial volume effects in emission tomography. Phys Med Biol. 2006;51:1857-1876.
11. Wilson DW, Tsui BMW. Noise properties of filtered-backprojection and ML-EM reconstructed emission tomography images. IEEE Trans Nucl Sci. 1993;40:1198-1203.
12. Sparks DN. Euclidean cluster analysis. J R Stat Soc Ser C Appl Stat. 1973;22:126-130.
13. Hoffman EJ, Cutler PD, Digby WM, Mazziotta JC. 3-D phantom to simulate cerebral blood flow and metabolic images for PET. IEEE Trans Nucl Sci. 1990;37:616-620.
14. Lamare F, Turzo A, Bizais Y, Le Rest CC, Visvikis D. Validation of a Monte Carlo simulation of the Philips Allegro/GEMINI PET systems using GATE. Phys Med Biol. 2006;51:943-962.
15. Reader AJ, Ally S, Bakatselos F, et al. One-pass list-mode EM algorithm for high-resolution 3-D PET image reconstruction into large arrays. IEEE Trans Nucl Sci. 2002;49:693-699.
16. 18F]FDG uptake in PET. Eur J Nucl Med Mol Imaging. 2003;30:344-353.
17. 18F]FDG PET. Eur J Nucl Med. 2001;28:1326-1335.
18. Pavese N, Gerhard A, Tai YF, et al. Microglial activation correlates with severity in Huntington disease: a clinical and PET study. Neurology. 2006;66:1638-1643.
19. Gebicke-Haerter PJ. Microarrays and expression profiling in microglia research and in inflammatory brain disorders. J Neurosci Res. 2005;81:327-341.
20. Banati RB. Visualising microglial activation in vivo. Glia. 2002;40:206-217.
21. Sapp E, Kegel KB, Aronin N, et al. Early and progressive accumulation of reactive microglia in the Huntington disease brain. J Neuropathol Exp Neurol. 2001;60:161-172.
22. Spinks TJ, Jones T, Bloomfield PM, et al. Physical characteristics of the ECAT EXACT3D positron tomograph. Phys Med Biol. 2000;45:2601-2618.
23. Gunn RN, Lammertsma AA, Hume SP, Cunningham VJ. Parametric imaging of ligand-receptor binding in PET using a simplified reference region model. Neuroimage. 1997;6:279-287.
24. 11C]-(R)-PK11195 brain studies. J Nucl Med. 2007;48:158-167.
25. Woods RP, Mazziotta JC, Cherry SR. MRI-PET registration with automated algorithm. J Comput Assist Tomogr. 1993;17:536-546.
26. Beyer T, Townsend DW, Brun T, et al. A combined PET/CT scanner for clinical oncology. J Nucl Med. 2000;41:1369-1379.
27. Shao Y, Cherry SR, Farahani K, et al. Simultaneous PET and MR imaging. Phys Med Biol. 1997;42:1965-1970.
28. Aston JA, Cunningham VJ, Asselin MC, Hammers A, Evans AC, Gunn RN. Positron emission tomography partial volume correction: estimation and algorithms. J Cereb Blood Flow Metab. 2002;22:1019-1034.