Plasma and urine aldosterone to plasma renin activity ratio in the diagnosis of primary aldosteronism

Journal of Hypertension

Volumn 26, Issue 5, 2008, Pages 981-988

  Bernini, Giampaolo ^a   Moretti, Angelica ^a   Orlandini, Cinzia ^a   Berti, Piero ^a   Miccoli, Paolo ^a   Bardini, Michele ^a   Taurino, Chiara ^a   Bernini, Matteo ^a   Salvetti, Antonio ^a  

^a UNIVERSITY OF PISA   (Italy)

Author keywords

Aldosterone; Aldosterone plasma renin activity ratio; Plasma renin activity; Primary aldosteronism

Indexed keywords

ALDOSTERONE;

ADENOMA; ADRENAL HYPERPLASIA; ADULT; ALDOSTERONE BLOOD LEVEL; ALDOSTERONE URINE LEVEL; ARTICLE; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; ESSENTIAL HYPERTENSION; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; PLASMA RENIN ACTIVITY; PRIMARY HYPERALDOSTERONISM; PRIORITY JOURNAL; RADIOIMMUNOASSAY; RECEIVER OPERATING CHARACTERISTIC; SCREENING;

EID: 42049112060     PISSN: 02636352     EISSN: None     Source Type: Journal    
DOI: 10.1097/HJH.0b013e3282f61f8c     Document Type: Article

References (50)

1. Mulatero P, Dluhy RG, Giacchetti G, Boscaro M, Veglio F, Stewart PM. Diagnosis of primary aldosteronism: from screening to subtype differentiation. Trends Endocrinol Metab 2005; 16:114-119.
2. Gordon RD, Ziesak MD, Tunny TJ, Stowasser M, Klemm SA. Evidence that primary aldosteronism may not be uncommon: 12% incidence among antihypertensive drug trial volunteers. Clin Exp Pharmacol Physiol 1993; 20:296-298.
3. Gordon RD, Stowasser M, Tunny TJ, Klemm SA, Rutherford JC. High incidence of primary aldosteronism in 199 patients referred with hypertension. Clin Exp Pharmacol Physiol 1994; 21:315-318.
4. Fardella CE, Mosso L, Gomez-Sanchez C, Cortes P, Soto J, Gomez L, et al. Primary hyperaldosteronism in essential hypertensives: prevalence, biochemical profile, and molecular biology. J Clin Endocrinol Metab 2000; 85:1863-1867.
5. Loh KC, Koay ES, Khaw MC, Emmanuel SC, Young WF Jr. Prevalence of primary aldosteronism among Asian hypertensive patients in Singapore. J Clin Endocrinol Metab 2000; 85:2854-2859.
6. Gordon RD, Stowasser M, Tunny TJ, Klemm SA, Rutherford JC. Mineralocorticoid hypertension. Lancet 1994; 344:240-243.
7. Rossi E, Regolisti G, Negro A, Sani C, Davoli S, Perazzoli F. High prevalence of primary aldosteronism using postcaptopril plasma aldosterone to renin ratio as a screening test among Italian hypertensives. Am J Hypertens 2002; 15:896-902.
8. Mulatero P, Rabbia F, Milan A, Paglieri C, Morello F, Chiandussi L, Veglio F. Drug effects on aldosterone/plasma renin activity ratio in primary aldosteronism. Hypertension 2002; 40:897-902.
9. Stowasser M, Gordon RD, Gunasekera TG, Cowley DC, Ward G, Archibald C, Smithers BM. High rate of detection of primary aldosteronism, including surgically treatable forms, after 'nonselective' screening of hypertensive patients. J Hypertens 2003; 21:2149-2157.
10. Mulatero P, Stowasser M, Loh KC, Fardella CE, Gordon RD, Mosso L, et al. Increased diagnosis of primary aldosteronism, including surgically correctable forms, in centers from five continents. J Clin Endocrinol Metab 2004; 89:1045-1050.
11. Fiquet-Kempf B, Launay-Mignot P, Bobrie G, Plouin PF. Is primary aldosteronism underdiagnosed in clinical practice? Clin Exp Pharmacol Physiol 2001; 28:1083-1086.
12. Kumar A, Lall SB, Ammini A, Peshin SS, Karmarkar MG, Talwar KK, Seth SD. Screening of a population of young hypertensives for primary hyperaldosteronism. J Hum Hypertens 1994; 8:731-732.
13. Lim PO, Dow E, Brennan G, Jung RT, MacDonald TM. High prevalence of primary aldosteronism in the Tayside hypertension clinic population. J Hum Hypertens 2000; 14:311-315.
14. Nishikawa T, Omura T. Clinical characteristics of primary aldosteronism: its prevalence and comparative studies on various causes of primary aldosteronism in Yokohama Rosai hospital. Biomed Pharmacother 2000; 54 (suppl 1):83-85.
15. Gallay BJ, Ahmad S, Xu L, Toivola B, Davidson RC. Screening for primary aldosteronism without discontinuing hypertensive medications: plasma aldosterone-renin ratio. Am J Kidney Dis 2001; 37:699-705.
16. Lim PO, Rodgers P, Cardale K, Watson AD, MacDonald TM. Potentially high prevalence of primary aldosteronism in a primary-care population. Lancet 1999; 353:40.
17. Jose A, Kaplan NM. Plasma renin activity in the diagnosis of primary aldosteronism: failure to distinguish primary aldosteronism from essential hypertension. Arch Intern Med 1969; 123:141-146.
18. McKenna TJ, Sequeira SJ, Heffernan A, Chambers J, Cunningham S. Diagnosis under random conditions of all disorders of the renin-angiotensin-aldosterone axis, including primary hyperaldosteronism. J Clin Endocrinol Metab 1991; 73:952-957.
19. Blumenfeld JD, Sealey JE, Schlussel Y, Vaughan ED Jr, Sos TA, Atlas SA, et al. Diagnosis and treatment of primary hyperaldosteronism. Ann Intern Med 1994; 121:877-885.
20. Montori VM, Schwartz GL, Chapman AB, Boerwinkle E, Turner ST. Validity of the aldosterone-renin ratio used to screen for primary aldosteronism. Mayo Clin Proc 2001; 76:877-882.
21. Hiramatsu K, Yamada T, Yukimura Y, Komiya I, Ichikawa K, Ishihara M, et al. A screening test to identify aldosterone-producing adenoma by measuring plasma renin activity. Results in hypertensive patients. Arch Intern Med 1981; 141:1589-1593.
22. Hamlet SM, Tunny TJ, Woodland E, Gordon RD. Is aldosterone/renin ratio useful to screen a hypertensive population for primary aldosteronism? Clin Exp Pharmacol Physiol 1985; 12:249-252.
23. Veglio F, Rabbia F, Mengozzi G, Mulatero P, Zocchi C, Martini G, et al. Assessment of a theresold value of the plasma aldosterone/plasma renin activity ratio in the screening for primary aldosteronism. Intern Med 1999; 7:65-71.
24. Schwartz GL, Turner ST. Screening for primary aldosteronism in essential hypertension: diagnostic accuracy of the ratio of plasma aldosterone concentration to plasma renin activity. Clin Chem 2005; 51:386-394.
25. Giacchetti G, Ronconi V, Lucarelli G, Boscaro M, Mantero F. Analysis of screening and confirmatory tests in the diagnosis of primary aldosteronism: need for a standardized protocol. J Hypertens 2006; 24:737-745.
26. Tiu SC, Choi CH, Shek CC, Ng YW, Chan FK, Ng CM, Kong AP. The use of aldosterone-renin ratio as a diagnostic test for primary hyperaldosteronism and its test characteristics under different conditions of blood sampling. J Clin Endocrinol Metab 2005; 90:72-78.
27. Lamarre-Cliche M, de Champlain J, Lacourciere Y, Poirier L, Karas M, Larochelle P. Effects of circadian rhythms, posture, and medication on renin-aldosterone interrelations in essential hypertensives. Am J Hypertens 2005; 18:56-64.
28. Doig J, Lees K, Reid J. The effect of drugs on the renin-angiotensin system in man. In: Robertson J, Nicholls M, editors. The renin-angiotensin system. London: Merk; 1993.
29. Johnston C. Angiotensin-converting enzyme inhibitors. In: Robertson J, Nicholls M, editors. The renin-angiotensin system. London: Merk; 1993.
30. Young WF Jr, Hogan MJ, Klee GG, Grant CS, van Heerden JA. Primary aldosteronism: diagnosis and treatment. Mayo Clin Proc 1990; 65:96-110.
31. Kaplan NM. Primary Aldosteronism. In: Kaplan NM, editor. Clinical hypertension. Baltimore, Maryland: Wilkins & Wilkins; 1998.
32. Young S, Shionoiri H, Takasaki I, Kihara M, Gotoh E. Hypertensive complications in patients with primary aldosteronism: a retrospective study. Curr Ther Res 1991; 50:317-324.
33. Nishimura M, Uzu T, Fujii T, Kuroda S, Nakamura S, Inenaga T, Kimura G. Cardiovascular complications in patients with primary aldosteronism. Am J Kidney Dis 1999; 33:261-266.
34. Tanabe A, Naruse M, Naruse K, Hase M, Yoshimoto T, Tanaka M, et al. Left ventricular hypertrophy is more prominent in patients with primary aldosteronism than in patients with other types of secondary hypertension. Hypertens Res 1997; 20:85-90.
35. Milliez P, Girerd X, Plouin PF, Blacher J, Safar ME, Mourad JJ. Evidence for an increased rate of cardiovascular events in patients with primary aldosteronism. J Am Coll Cardiol 2005; 45:1243-1248.
36. Castro OL, Yu X, Kem DC. Diagnostic value of the postcaptopril test in primary aldosteronism. Hypertension 2002; 39:935-938.
37. Agharazii M, Douville P, Grose JH, Lebel M. Captopril suppression versus salt loading in confirming primary aldosteronism. Hypertension 2001; 37:1440-1443.
38. Schirpenbach C, Seiler L, Maser-Gluth C, Rudiger F, Nickel C, Beuschlein F, Reincke M. Confirmatory testing in normokalaemic primary aldosteronism: the value of the saline infusion test and urinary aldosterone metabolites. Eur J Endocrinol 2006; 154:865-873.
39. Rossi GP, Belfiore A, Bernini G, Desideri G, Fabris B, Ferri C, et al. Prospective evaluation of the saline infusion test for excluding primary aldosteronism due to aldosterone-producing adenoma. J Hypertens 2007; 25:1433-1442.
40. Rossi GP, Bernini G, Caliumi C, Desideri G, Fabris B, Ferri C, et al. A prospective study of the prevalence of primary aldosteronism in 1125 hypertensive patients. J Am Coll Cardiol 2006; 48:2293-2300.
41. Sartori M, Calo LA, Mascagna V, Realdi A, Macchini L, Ciccariello L, et al. Aldosterone and refractory hypertension: a prospective cohort study. Am J Hypertens 2006; 19:373-379.
42. Chain S, Luciardi HL, Feldman G, Berman SG, Herrera RN, Ochoa J, et al. Diagnostic role of new Dopper index in assesment of renal artery stenosis. Cardiovasc Ultrasound 2006; 4:1-7.
43. Sealey JE, Gerten-Banes J, Laragh JH. The renin system: variations in man measured by radioimmunoassay or bioassay. Kidney Int 1972; 1:240-253.
44. Hanley JA, McNeil BJ. The meaning and use of the area under a receiver operating characteristic (ROC) curve. Radiology 1982; 143:29-36.
45. Nicholls M, Robertson J. Changes in renin secretion: physiological, pathophysiological, pharmacological, and epidemiological expression. In: Robertson J, Nicholls M, editors. The renin-angiotensin system. London: Merk; 1993.
46. Kem DC, Weinberger MH, Gomez-Sanchez C, Kramer NJ, Lerman R, Furuyama S, Nugent CA. Circadian rhythm of plasma aldosterone concentration in patients with primary aldosteronism. J Clin Invest 1973; 52:2272-2277.
47. Kem DC, Weinberger MH, Higgins JR, Kramer NJ, Gomez-Sanchez C, Holland OB. Plasma aldosterone response to ACTH in primary aldosteronism and in patients with low renin hypertension. J Clin Endocrinol Metab 1978; 46:552-560.
48. Irony I, Kater CE, Biglieri EG, Shackleton CH. Correctable subsets of primary aldosteronism. Primary adrenal hyperplasia and renin responsive adenoma. Am J Hypertens 1990; 3:576-582.
49. Tanabe A, Naruse M, Takagi S, Tsuchiya K, Imaki T, Takano K. Variability in the renin/aldosterone profile under random and standardized sampling conditions in primary aldosteronism. J Clin Endocrinol Metab 2003; 88:2489-2494.
50. Mulatero P, Milan A, Fallo F, Regolisti G, Pizzolo F, Fardella C, et al. Comparison of confirmatory tests for the diagnosis of primary aldosteronism. J Clin Endocrinol Metab 2006; 91:2618-2623.