The interfering effect and probable mechanism of neuregulin-1 β on cerebral ischemia reperfusion injury in mice

Acta Anatomica Sinica

Volumn 39, Issue 1, 2008, Pages 35-39

  Wang, Tao ^a   Du, Fang ^a   Guo, Yun Liang ^a   Qin, Li Hua ^b   Luan, Li Ju ^b   Ning, Li Xia ^a  

^a QINGDAO UNIVERSITY MEDICAL COLLEGE   (China)

^b PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

Apoptosis; Brain edema; Cerebral ischemia; Immunohistochemistry; Mouse; Neuregulin; Reperfusion injury

Indexed keywords

AQUAPORIN 4; GROWTH FACTOR; NEUREGULIN 1BETA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ASTROCYTE; BRAIN EDEMA; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; BRAIN NERVE CELL; BRAIN WATER; CELL COUNT; CONTROLLED STUDY; DRUG MECHANISM; IMMUNOFLUORESCENCE TEST; IMMUNOHISTOCHEMISTRY; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NEUROPROTECTION; NONHUMAN; PROTEIN EXPRESSION; REPERFUSION INJURY; STATISTICAL SIGNIFICANCE;

MUS;

EID: 42049108405     PISSN: 05291356     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. Guo YL. The biological effects of neuregulins[J]. Acta Academiae Medicinae Qingdao Universitatis, 2006, 42(1):1-3.
2. Wang T, Du F, Guo YL. Neuregulins and their signal transduction mechanism [J]. International Journal of Pathology and Clinical Medicine, 2006, 26(1):48-51.
3. Wang T, Do F, Guo YL. The Neuroprotective effects of neuregulins in cerebral ischemia [J]. International Journal of Cerebrovascular Diseases, 2006, 14(10):789-792.
4. Xu Z, Jiang J, Ford G, et al. Neuregulin-1 is neuroprotective and attenuates inflammatory responses induced by ischemic stroke [J]. Biochem Biophys Res Commun, 2004, 322(2):440-446.
5. Burden S, Yarden Y. Neuregulins and their receptors: a versatile signaling module in organogenesis and oncogenesis[J]. Neuron, 1997, 18(6): 847-855.
6. Bederson JB, Pitts LH, Tsuji M, et al. Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination[J]. Stroke, 1986, 17(3):472-476.
7. Liu XJ, Sui QL, Kong LQ, et al. Evaluation of cerebral ischemia and reperfusion injury with magnetic resonance diffusion weighted imaging in rabbits[J]. Acta Anatomica Sinaca, 2006, 37(6):700-704.
8. Wang T, Du F, Yang XW, et al. Establishment and evaluation of model with middle celebral artery occusion in mice[J]. Chinese Journal of Clinical Nearosciences, 2007, 15(1):71-75.
9. Longa EZ, Weinstein PR, Carlson S, et al. Reversible middle cerebral artery occlusion without craniectomy in rats [J]. Stroke, 1989, 20(1): 84-91.
10. Venero JL, Vizuete ML, Machado A, et al. Aquaporins in the central nervous system[J]. Prog Neurobiol, 2001, 63(3): 321-336.
11. King LS, Agre P. Pathophysiology of the aquaporin water channels[J]. Annu Rev Physiol, 1996, 58(4):619-648.
12. Manley GT, Fujimura M, Ma T, et al. Aquaporin-4 deletion in mice reduces brain edema after acute water intoxication and ischemic stroke [J]. Nat Med, 2000, 6(2):159-163.
13. Taniguchi M, Yamashita T, Kumura E, et al. Induction of aquaporin-4 water channel mRNA after focal cerebral ischemia in rat[J]. Brain Res Mol Brain Res, 2000, 78(1-2):131-137.
14. Lan XF, Yao WX, Guo Y. Study on correlation between the expression of AQP-4 and brain edema on cerebral ischemic reperfusion in rats[J]. Journal of Apoplexy and Nervous Diseases, 2004, 21(5):409-411.
15. Xu Z, Ford GD, Croslan DR, et al. Neuroprotection by neuregulin-1 following focal stroke is associated with the attenuation of ischemia-induced pro-inflammatory and stress gene expression [J]. Neurobiol Dis, 2005, 19(3):461-470.