Basil oil is a promising skin penetration enhancer for transdermal delivery of labetolol hydrochloride

Drug Development and Industrial Pharmacy

Volumn 34, Issue 4, 2008, Pages 384-389

  Jain, Rahul ^a   Aqil, Mohammed ^a   Ahad, Abdul ^a   Ali, Asgar ^a   Khar, Roop K ^a  

^a HAMDARD UNIVERSITY   (India)

Author keywords

Basil oil; Labetolol; Penetration enhancer; Terpenes; Transdermal

Indexed keywords

ALCOHOL; BASIL OIL; CAMPHOR; CLOVE OIL; LABETALOL; TERPENE; THYMOL; UNCLASSIFIED DRUG; VEGETABLE OIL; WATER;

ABDOMEN; ANIMAL TISSUE; ARTICLE; BASIL; DIFFUSION COEFFICIENT; DRUG SOLUBILITY; MALE; NONHUMAN; PARTITION COEFFICIENT; RAT; SKIN PENETRATION; STEADY STATE; THERMODYNAMICS;

ANIMALS; ANTIHYPERTENSIVE AGENTS; CAMPHOR; CLOVE OIL; EXCIPIENTS; LABETALOL; MALE; PERMEABILITY; PLANT OILS; RATS; RATS, WISTAR; SKIN ABSORPTION; TERPENES; THERMODYNAMICS; THYMOL;

EID: 42049107749     PISSN: 03639045     EISSN: 15205762     Source Type: Journal    
DOI: 10.1080/03639040701657958     Document Type: Article

References (37)

1. Buyuktimkin, S., Buyuktimkin, N., & Rytting, J. H. (1993). Synthesis and enhancing effect of Dodecyl 2-(N, N- Dimethylamino) propionate on the transdermal delivery of indomethacin, clonidine, and hydrocortisone. Pharma. Resarch, 10, 1632-1637.
2. Chena, H., Mendelsohna, R., Rerekb, M. E., & Mooreb, D. J. (2000). Fourier transform infrared spectroscopy and differential scanning calorimetry studies of fatty acid homogeneous ceramide 2. Biochimica et Biophysica Acta (BBA) - Biomembranes, 1468, 293-303.
3. Cornwell, P. A., & Barry, B. W. (1993). The routes of penetration of ions and 5-fluorouracil across human skin and the mechanisms of action of terpene skin penetration enhancers. Int. J. Pharm., 94, 189-194.
4. nd ed., pp. L1-L3) London: Churchill Livingstone.
5. El-Kattan, A. F., Asbill, C. S., & Michniak, B. B. (2000). The effect of terpene enhancer lipophilicity on the percutaneous permeation of hydrocortisone formulated in hpmc gel systems. Int. J. Pharm., 198, 179-189.
6. th ed., pp. 1009-1019). Easton, PA: Mack Publishing.
7. Godwin, D. A., & Michniak, B. B. (1999). Influence of drug lipophilicity on terpenes as penetration enhancers. Drug Dev. Pharm., 25, 905-915.
8. Hadgraft, J. (2001). Modulation of the barrier function of the skin. Skin Pharmacol. Appl. Skin Physiol., 14, 72-81.
9. Harvengt, C. (1991). Labetalol hepatotoxicity. Ann. Intern. Med., 114, 341-368.
10. Hypertension study group. (2001). Prevalence, awareness, treatment and control of hypertension among the elderly in Bangladesh and India: A multicentre study. Bull. World Health Org., 79, 490-500.
11. Inamori, T., Ghanem, A. H., Higuchi, W. I., & Srinivasan, V. (1994). Macromolecule transport in an effective pore size of ethanol pre-treated human epidermal membrane. Int. J. Pharm., 105, 113-123.
12. Jain, A. K., & Panchagnula, R. (2003). Effect of temperature on imipramine hydrochloride permeation: Role of lipid bilayer arrangement and chemical composition of rat skin. Int. J. Pharm., 250, 287-293.
13. Jain, A. K., Thomas, N. S., & Panchagnula, R. (2002). Transdermal drug delivery of imipramine hydrochloride: I. Effect of terpenes. J. Control. Release., 79, 93-101.
14. Krishnaiah, Y. S., Satyanarayana, V., & Bhasker, P. (2003). Enhanced percutaneous permeability of nicardipine hydrochloride by carvone across the rat abdominal skin. Drug Dev. Ind. Pharm., 29(2), 191-202.
15. Law, S., Wertz, P. W., Swartzendruber, D. C., & Squier, C. A. (1995). Regional variation in content, composition and organization of porcine epithelial barrier lipids revealed by thin-layer chromatography and transmission electron microscopy. Arch. Oral Biol., 40, 1085-1091.
16. Li, S. K., Suh, W., Parikh, H. H., Ghanem, A. H., Mehta, S. C., Peck, K. D., & Higuchi, W. I. (1998). Lag time data for characterizing the pore pathway of intact and chemically pretreated human epidermal membrane. Int. J. Pharm., 170, 93-108.
17. Magnusson, M., Runn, P., Karlsson, K., & Koskinen, L. O. D. (1997). Terpenes and ethanol enhance the transdermal permeation of the tripeptide thyrotropin releasing hormone in human epidermis. Int. J. Pharm., 157, 113-121.
18. th ed., pp. 22-52). New Delhi: B. I. Waverly.
19. McNeil, J. J., Anderson, A. E., Louis, W. J., & Morgan, D. J. (1979). Pharmacokinetics and pharmacodynamic studies of labetalol in hypertensive subjects. Br. J. Clin. Pharmacol., 8, 157S-161S.
20. nd ed., pp. 698-699) London: The Pharmaceutical Press.
21. Mohimi, H., Williams, A. C., & Barry, B. W. (1997). A lamellar matrix model for stratum corneum intercellular lipids V. Effects of terpenes penetration enhancers on the structure and thermal behavior of the matrix. Int. J. Pharm., 446, 41-54.
22. Moore, D. J., & Rerek, M. E. (2000). Insights into the molecular organization of lipids in the skin barrier from infrared spectroscopy studies of stratum corneum lipid models. Acta Derm. Venereol., 208, 16-22.
23. Muir, K. T., & Ismael, J. H. (1984). High performance liquid chromatographic method for the determination of Labetalol in plasma using ultraviolet detection. J. Chromatogr. Biomed. Appl., 305, 222-227.
24. Naik, A., Kalia, Y. N, & Guy, R. H. (2000). Transdermal drug delivery: Overcoming the skin's barrier function. Pharm. Sci. Tech. Today, 3, 318-326.
25. Narishetty, S. T. K., & Panchagnula, R. (2004). Transdermal delivery of zidovudine: Effect of terpenes and their mechanism of action. J. Control. Release., 95, 367-379.
26. Ogiso, T., Hirota, T., Iwaki, M., Hino, T., & Tanino, T. (1998). Effect of temperature on percutaneous absorption of terodiline, and relationship between penetration and fluidity of the stratum corneum lipids. Int. J. Pharm., 176, 63-72.
27. Okabe, H., Obata, Y., Takayama, K., & Nagai, T. (1990). Percutaneous absorption enhancing effect and skin irritation of monocyclic monoterpenes. Drug Res. Deliv., 6, 229-238.
28. Park, E. S., Chang, S. J., Rhee, Y. S., & Chi, S. C. (2001). Effects of adhesives and permeation enhancers on the skin permeation of captopril. Drug Dev. Ind. Pharm., 27, 975-980.
29. Peck, K. D., Ghanem, A. H., & Higuchi, W. I. (1994). Polar molecules through and effective pore radii estimates of intact and ethanol treated human epidermal membrane. Pharm. Res. 11, 1306-1314.
30. Ropke, C. D., Telma, M. K., Rodrigues, R. M., Silva, V. V, Barros, S., Sawada, T. C. H., Kato, M. J., & Barros, S. B. M. (2002). Evaluation of percutaneous absorption of 4-nerolidylcathecol from four topical formulations. Int. J. Pharm., 249, 109-116.
31. Sinha, V. R, & Kaur, M. P. (2000). Permeation enhancers for transdermal drug delivery. Drug Dev. Ind. Pharm., 26, 1131-1140.
32. rd ed., pp. 918-919). London: The Pharmaceutical Press.
33. Vaddi, H. K., Ho, P. C., Chan, Y. W., & Chan, S. Y. (2002). Terpenes in ethanol: Haloperidol permeation and partition through human skin and stratum corneum changes. J. Control. Release., 81, 121-133.
34. Williams, A. C., & Barry, B. W. (1991). Terpenes and the lipid-protein-partitioning theory of skin penetration enhancement. Pharm. Res., 8, 17-24.
35. Williams A. C., & Barry B. W. (2004). Penetration enhancers. Adv. Drug Del., 56, 603-618.
36. World Health Organization Reports. (2003). The magnitude of the problem of poor adherence. Geneva: WHO.
37. Yach., D. (2002). Progress in addressing risk to health: Implications to mega countries. World Health Organization Mega Country meeting. Geneva.