-
1
-
-
0022625903
-
The influence of seizure type on the efficacy of plasma concentrations of phenytoin, phenobarbital and carbamazepine
-
Schmidt D, Einicke I, Haenel F. The influence of seizure type on the efficacy of plasma concentrations of phenytoin, phenobarbital and carbamazepine. Arch Neurol. 1986;43:263-265.
-
(1986)
Arch Neurol
, vol.43
, pp. 263-265
-
-
Schmidt, D.1
Einicke, I.2
Haenel, F.3
-
2
-
-
0031671913
-
Therapeutic drug monitoring - antiepileptic drugs
-
Eadie MJ. Therapeutic drug monitoring - antiepileptic drugs. Br J Clin Pharmacol. 1998;46:185-193.
-
(1998)
Br J Clin Pharmacol
, vol.46
, pp. 185-193
-
-
Eadie, M.J.1
-
3
-
-
0030988516
-
Plasma drug concentration monitoring of anticonvulsants. Practical guidelines
-
Johannessen SI. Plasma drug concentration monitoring of anticonvulsants. Practical guidelines. CNS Drugs. 1997;7:349-365.
-
(1997)
CNS Drugs
, vol.7
, pp. 349-365
-
-
Johannessen, S.I.1
-
4
-
-
0034100739
-
Is there a role for therapeutic drug monitoring of new anticonvulsants?
-
Perucca E. Is there a role for therapeutic drug monitoring of new anticonvulsants? Clin Pharmacokinet. 2000;38:191-204.
-
(2000)
Clin Pharmacokinet
, vol.38
, pp. 191-204
-
-
Perucca, E.1
-
5
-
-
0038442675
-
Therapeutic drug monitoring of the newer antiepileptic drugs
-
Johannessen SI, Battino D, Berry DJ, et al. Therapeutic drug monitoring of the newer antiepileptic drugs. Ther Drug Monit. 2003;25:347-363.
-
(2003)
Ther Drug Monit
, vol.25
, pp. 347-363
-
-
Johannessen, S.I.1
Battino, D.2
Berry, D.J.3
-
6
-
-
33750366552
-
Pharmacokinetic variability of newer antiepileptic drugs: When is monitoring needed?
-
Johannessen SI, Tomson T. Pharmacokinetic variability of newer antiepileptic drugs: when is monitoring needed? Clin Pharmacokinet. 2006;45:1061-1075.
-
(2006)
Clin Pharmacokinet
, vol.45
, pp. 1061-1075
-
-
Johannessen, S.I.1
Tomson, T.2
-
7
-
-
25144516296
-
Pregnancy-induced changes in pharmacokinetics: A mechanistic-based approach
-
Anderson GD. Pregnancy-induced changes in pharmacokinetics: a mechanistic-based approach. Clin Pharmacokinet. 2005;44:989-1008.
-
(2005)
Clin Pharmacokinet
, vol.44
, pp. 989-1008
-
-
Anderson, G.D.1
-
8
-
-
0036282140
-
Children versus adults: Pharmacokinetic and adverseeffect differences
-
Anderson GD. Children versus adults: pharmacokinetic and adverseeffect differences. Epilepsia. 2002;43(Suppl 3):53-59.
-
(2002)
Epilepsia
, vol.43
, Issue.SUPPL. 3
, pp. 53-59
-
-
Anderson, G.D.1
-
9
-
-
33947223462
-
Pharmacokinetics and therapeutic drug monitoring of newer antiepileptic drugs during pregnancy and the puerperium
-
Tomson T, Battino D. Pharmacokinetics and therapeutic drug monitoring of newer antiepileptic drugs during pregnancy and the puerperium. Clin Pharmacokinet. 2007;46:209-219.
-
(2007)
Clin Pharmacokinet
, vol.46
, pp. 209-219
-
-
Tomson, T.1
Battino, D.2
-
10
-
-
72849166751
-
Clinical and electroencephalographic correlations with serum levels of diphenylhydantoin
-
Buchthal F, Svensmark O, Schiller PJ. Clinical and electroencephalographic correlations with serum levels of diphenylhydantoin. Arch Neurol. 1960;2:624-630.
-
(1960)
Arch Neurol
, vol.2
, pp. 624-630
-
-
Buchthal, F.1
Svensmark, O.2
Schiller, P.J.3
-
11
-
-
42049095723
-
Effects of phenytoin in patients with epilepsy in relation to its concentration in plasma
-
Davis DS, Prichard BNC, eds, Baltimore: University Park Press;
-
Lund L. Effects of phenytoin in patients with epilepsy in relation to its concentration in plasma. In: Davis DS, Prichard BNC, eds. Biological Effects of Drugs in Relation to Their Plasma Concentrations. Baltimore: University Park Press; 1972:227-238.
-
(1972)
Biological Effects of Drugs in Relation to Their Plasma Concentrations
, pp. 227-238
-
-
Lund, L.1
-
12
-
-
0000673072
-
Diphenylhydantoin metabolism, blood levels, and toxicity
-
Kutt H, Winters W, Kokenge R, et al. Diphenylhydantoin metabolism, blood levels, and toxicity. Arch Neurol. 1964;11:642-648.
-
(1964)
Arch Neurol
, vol.11
, pp. 642-648
-
-
Kutt, H.1
Winters, W.2
Kokenge, R.3
-
16
-
-
0024589068
-
Human brain phenytoin: Correlation with unbound and total serum concentrations
-
Friel PN, Ojemann GA, Rapport RL, et al. Human brain phenytoin: correlation with unbound and total serum concentrations. Epilepsy Res. 1989;3:82-85.
-
(1989)
Epilepsy Res
, vol.3
, pp. 82-85
-
-
Friel, P.N.1
Ojemann, G.A.2
Rapport, R.L.3
-
17
-
-
0017653781
-
Distribution of anticonvulsant drugs in gray and white matter of human brain
-
Harvey CD, Sherwin AL, Van Der Kleijn E. Distribution of anticonvulsant drugs in gray and white matter of human brain. Can J Neurol Sci. 1977;4:89-92.
-
(1977)
Can J Neurol Sci
, vol.4
, pp. 89-92
-
-
Harvey, C.D.1
Sherwin, A.L.2
Van Der Kleijn, E.3
-
18
-
-
0016801454
-
Brain concentrations of phenytoin, phenobarbital and primidone in epileptic patients
-
Houghton GW, Richens A, Toseland PA, et al. Brain concentrations of phenytoin, phenobarbital and primidone in epileptic patients. Eur J Clin Pharmacol. 1975;9:73-78.
-
(1975)
Eur J Clin Pharmacol
, vol.9
, pp. 73-78
-
-
Houghton, G.W.1
Richens, A.2
Toseland, P.A.3
-
19
-
-
0020310136
-
Blood-brain barrier transfer and cerebral uptake of antiepileptic drugs
-
Paulson OB, Gyory A, Hertz MM. Blood-brain barrier transfer and cerebral uptake of antiepileptic drugs. Clin Pharmacol Ther. 1982;32:466-477.
-
(1982)
Clin Pharmacol Ther
, vol.32
, pp. 466-477
-
-
Paulson, O.B.1
Gyory, A.2
Hertz, M.M.3
-
20
-
-
0027538206
-
Postmortem concentrations of phenobarbital, carbamazepine, and its metabolite carbamazepine-10,11-epoxide in different regions of the brain and in serum: Analysis of autoptic specimens from 51 epileptic patients
-
Rambeck B, Schnabel R, May T, et al. Postmortem concentrations of phenobarbital, carbamazepine, and its metabolite carbamazepine-10,11-epoxide in different regions of the brain and in serum: analysis of autoptic specimens from 51 epileptic patients. Ther Drug Monit. 1993;15:91-98.
-
(1993)
Ther Drug Monit
, vol.15
, pp. 91-98
-
-
Rambeck, B.1
Schnabel, R.2
May, T.3
-
21
-
-
0028111351
-
Phenytoin concentrations in the human brain: An in vivo microdialysis study
-
Scheyer RD, During MJ, Hochholzer JM, et al. Phenytoin concentrations in the human brain: an in vivo microdialysis study. Epilepsy Res. 1994;18:227-232.
-
(1994)
Epilepsy Res
, vol.18
, pp. 227-232
-
-
Scheyer, R.D.1
During, M.J.2
Hochholzer, J.M.3
-
23
-
-
0016137236
-
Human brain, cerebrospinal fluid, and plasma concentrations of diphenylhydantoin and phenobarbital
-
Vajda F, Williams FM, Davidson S, et al. Human brain, cerebrospinal fluid, and plasma concentrations of diphenylhydantoin and phenobarbital. Clin Pharmacol Ther. 1974;15:597-603.
-
(1974)
Clin Pharmacol Ther
, vol.15
, pp. 597-603
-
-
Vajda, F.1
Williams, F.M.2
Davidson, S.3
-
24
-
-
0028146558
-
Measurement of carbamazepine and carbamazepine epoxide in the human brain using in vivo microdialysis
-
Scheyer RD, During MJ, Spencer DD, et al. Measurement of carbamazepine and carbamazepine epoxide in the human brain using in vivo microdialysis. Neurology. 1994;44:1469-1472.
-
(1994)
Neurology
, vol.44
, pp. 1469-1472
-
-
Scheyer, R.D.1
During, M.J.2
Spencer, D.D.3
-
25
-
-
0028340428
-
Concentrations of carbamazepine and carbamazepine-10, 11-epoxide in serum, brain tumors and paratumorous cortex: A prospective study of 37 neurosurgically treated epileptic patients
-
Schnabel R, Rambeck B, May TW, et al. Concentrations of carbamazepine and carbamazepine-10, 11-epoxide in serum, brain tumors and paratumorous cortex: a prospective study of 37 neurosurgically treated epileptic patients. Eur Neurol. 1994;34:213-220.
-
(1994)
Eur Neurol
, vol.34
, pp. 213-220
-
-
Schnabel, R.1
Rambeck, B.2
May, T.W.3
-
26
-
-
0026697252
-
Low and variable presence of valproic acid in human brain
-
Shen DD, Ojemann GA, Rapport RL, et al. Low and variable presence of valproic acid in human brain. Neurology. 1992;42:582-585.
-
(1992)
Neurology
, vol.42
, pp. 582-585
-
-
Shen, D.D.1
Ojemann, G.A.2
Rapport, R.L.3
-
27
-
-
33749254410
-
Therapeutic monitoring of antiepileptic drugs during pregnancy and in the postpartum period: Is it useful?
-
Adab N. Therapeutic monitoring of antiepileptic drugs during pregnancy and in the postpartum period: is it useful? CNS Drugs. 2006;20:791-800.
-
(2006)
CNS Drugs
, vol.20
, pp. 791-800
-
-
Adab, N.1
-
28
-
-
33646850091
-
Can pharmacokinetic variability be controlled for the patient's benefit? The place of TDM for new AEDs
-
Johannessen SI. Can pharmacokinetic variability be controlled for the patient's benefit? The place of TDM for new AEDs. Ther Drug Monit. 2005;27:710-713.
-
(2005)
Ther Drug Monit
, vol.27
, pp. 710-713
-
-
Johannessen, S.I.1
-
29
-
-
10844220718
-
Correlation analysis between anticonvulsant ED50 values of antiepileptic drugs in mice and rats and their therapeutic doses and plasma levels
-
Bialer M, Twyman RE, White HS. Correlation analysis between anticonvulsant ED50 values of antiepileptic drugs in mice and rats and their therapeutic doses and plasma levels. Epilepsy Behav. 2004;5:866-872.
-
(2004)
Epilepsy Behav
, vol.5
, pp. 866-872
-
-
Bialer, M.1
Twyman, R.E.2
White, H.S.3
-
30
-
-
0025175901
-
Generic substitution for antiepileptic drugs
-
Nuwer M, Browne T, Dodson W, et al. Generic substitution for antiepileptic drugs. Neurology. 1990;40:1647-1651.
-
(1990)
Neurology
, vol.40
, pp. 1647-1651
-
-
Nuwer, M.1
Browne, T.2
Dodson, W.3
-
31
-
-
34247244258
-
Position statement on the coverage of anticonvulsant drugs for the treatment of epilepsy
-
Liow K, Barkley GL, Pollard JR, et al. Position statement on the coverage of anticonvulsant drugs for the treatment of epilepsy. Neurology. 2007;68:1249-1250.
-
(2007)
Neurology
, vol.68
, pp. 1249-1250
-
-
Liow, K.1
Barkley, G.L.2
Pollard, J.R.3
-
32
-
-
35148836175
-
Generic products of antiepileptic drugs (AEDs): Is it an issue?
-
Bialer M. Generic products of antiepileptic drugs (AEDs): is it an issue? Epilepsia. 2007;48:1825-1832.
-
(2007)
Epilepsia
, vol.48
, pp. 1825-1832
-
-
Bialer, M.1
-
33
-
-
0028948839
-
A theoretical basis for a biopharmaceutic drug classification: The correlation of in vitro drug product dissolution and in vivo bioavailability
-
Amidon GL, Lennernas H, Shah VP, et al. A theoretical basis for a biopharmaceutic drug classification: the correlation of in vitro drug product dissolution and in vivo bioavailability. Pharm Res. 1995;12:413-420.
-
(1995)
Pharm Res
, vol.12
, pp. 413-420
-
-
Amidon, G.L.1
Lennernas, H.2
Shah, V.P.3
-
34
-
-
17644380257
-
Predicting drug disposition via application of BCS: Transport/absorption/elimination interplay and development of a biopharmaceutics drug disposition classification system
-
Wu CY, Benet LZ. Predicting drug disposition via application of BCS: transport/absorption/elimination interplay and development of a biopharmaceutics drug disposition classification system. Pharm Res. 2005;22:11-23.
-
(2005)
Pharm Res
, vol.22
, pp. 11-23
-
-
Wu, C.Y.1
Benet, L.Z.2
-
35
-
-
3843097202
-
Classification of orally administered drugs on the World Health Organization Model List of Essential Medicines according to the biopharmaceutics classification system
-
Lindenberg M, Kopp S, Dressman JB. Classification of orally administered drugs on the World Health Organization Model List of Essential Medicines according to the biopharmaceutics classification system. Eur J Pharm Biopharm. 2004;58:265-278.
-
(2004)
Eur J Pharm Biopharm
, vol.58
, pp. 265-278
-
-
Lindenberg, M.1
Kopp, S.2
Dressman, J.B.3
-
36
-
-
0026564937
-
The bioinequivalence of carbamazepine tablets with a history of clinical failures
-
Meyer MC, Straughn AB, Jarvi EJ, et al. The bioinequivalence of carbamazepine tablets with a history of clinical failures. Pharm Res. 1992;9:1612-1616.
-
(1992)
Pharm Res
, vol.9
, pp. 1612-1616
-
-
Meyer, M.C.1
Straughn, A.B.2
Jarvi, E.J.3
-
37
-
-
0023724557
-
Compliance during treatment of epilepsy
-
Leppik IE. Compliance during treatment of epilepsy. Epilepsia. 1988;29(Suppl 2):S79-84.
-
(1988)
Epilepsia
, vol.29
, Issue.SUPPL. 2
-
-
Leppik, I.E.1
-
38
-
-
0024343414
-
How often is medication taken as prescribed? A novel assessment technique
-
Cramer JA, Mattson RH, Prevey ML, et al. How often is medication taken as prescribed? A novel assessment technique. JAMA. 1989;261:3273-3277.
-
(1989)
JAMA
, vol.261
, pp. 3273-3277
-
-
Cramer, J.A.1
Mattson, R.H.2
Prevey, M.L.3
-
39
-
-
0027977092
-
Status epilepticus and antiepileptic medication levels
-
Barry E, Hauser WA. Status epilepticus and antiepileptic medication levels. Neurology. 1994;44:47-50.
-
(1994)
Neurology
, vol.44
, pp. 47-50
-
-
Barry, E.1
Hauser, W.A.2
-
40
-
-
0242606931
-
Postictal serum levels of antiepileptic drugs for detection of noncompliance
-
Specht U, Elsner H, May TW, et al. Postictal serum levels of antiepileptic drugs for detection of noncompliance. Epilepsy Behav. 2003;4:487-495.
-
(2003)
Epilepsy Behav
, vol.4
, pp. 487-495
-
-
Specht, U.1
Elsner, H.2
May, T.W.3
-
41
-
-
0021125201
-
Do saliva concentrations predict plasma unbound theophylline concentrations? A problem re-examined
-
Knott C, Bateman M, Reynolds F. Do saliva concentrations predict plasma unbound theophylline concentrations? A problem re-examined. Br J Clin Pharmacol. 1984;17:9-14.
-
(1984)
Br J Clin Pharmacol
, vol.17
, pp. 9-14
-
-
Knott, C.1
Bateman, M.2
Reynolds, F.3
-
42
-
-
0021319502
-
The place of saliva in antiepileptic drug monitoring
-
Knott C, Reynolds F. The place of saliva in antiepileptic drug monitoring. Ther Drug Monit. 1984;6:35-41.
-
(1984)
Ther Drug Monit
, vol.6
, pp. 35-41
-
-
Knott, C.1
Reynolds, F.2
-
43
-
-
0033019029
-
Therapeutic drug concentration monitoring using saliva samples. Focus on anticonvulsants
-
Liu H, Delgado MR. Therapeutic drug concentration monitoring using saliva samples. Focus on anticonvulsants. Clin Pharmacokinet. 1999;36:453-470.
-
(1999)
Clin Pharmacokinet
, vol.36
, pp. 453-470
-
-
Liu, H.1
Delgado, M.R.2
-
44
-
-
34447510947
-
Saliva and serum levetiracetam concentrations in patients with epilepsy
-
Mecarelli O, Li Voti P, Pro S, et al. Saliva and serum levetiracetam concentrations in patients with epilepsy. Ther Drug Monit. 2007;29:313-318.
-
(2007)
Ther Drug Monit
, vol.29
, pp. 313-318
-
-
Mecarelli, O.1
Li Voti, P.2
Pro, S.3
-
46
-
-
26444528564
-
Stability of salivary concentrations of the newer antiepileptic drugs in the postal system
-
Jones MD, Ryan M, Miles MV, et al. Stability of salivary concentrations of the newer antiepileptic drugs in the postal system. Ther Drug Monit. 2005;27:576-579.
-
(2005)
Ther Drug Monit
, vol.27
, pp. 576-579
-
-
Jones, M.D.1
Ryan, M.2
Miles, M.V.3
-
47
-
-
0019216747
-
Status epilepticus. Causes, clinical features and consequences in 98 patients
-
Aminoff MJ, Simon RP. Status epilepticus. Causes, clinical features and consequences in 98 patients. Am J Med. 1980;69:657-666.
-
(1980)
Am J Med
, vol.69
, pp. 657-666
-
-
Aminoff, M.J.1
Simon, R.P.2
-
48
-
-
0023786462
-
Status epilepticus in children: Etiology, clinical features, and outcome
-
Dunn DW. Status epilepticus in children: etiology, clinical features, and outcome. J Child Neurol. 1988;3:167-173.
-
(1988)
J Child Neurol
, vol.3
, pp. 167-173
-
-
Dunn, D.W.1
-
50
-
-
34347355612
-
Genetics of epilepsy: Epilepsy Research Foundation workshop report
-
Sisodiya S, Cross JH, Blumcke I, et al. Genetics of epilepsy: Epilepsy Research Foundation workshop report. Epileptic Disord. 2007;9:194-236.
-
(2007)
Epileptic Disord
, vol.9
, pp. 194-236
-
-
Sisodiya, S.1
Cross, J.H.2
Blumcke, I.3
-
51
-
-
0034037772
-
CYP2C19 polymorphism effect on phenobarbitone. Pharmacokinetics in Japanese patients with epilepsy: Analysis by population pharmacokinetics
-
Mamiya K, Hadama A, Yukawa E, et al. CYP2C19 polymorphism effect on phenobarbitone. Pharmacokinetics in Japanese patients with epilepsy: analysis by population pharmacokinetics. Eur J Clin Pharmacol. 2000;55:821-825.
-
(2000)
Eur J Clin Pharmacol
, vol.55
, pp. 821-825
-
-
Mamiya, K.1
Hadama, A.2
Yukawa, E.3
-
52
-
-
0035081487
-
P-hydroxylation of phenobarbital: Relationship to (S)-mephenytoin hydroxylation (CYP2C19) polymorphism
-
Hadama A, Ieiri I, Morita T, et al. P-hydroxylation of phenobarbital: relationship to (S)-mephenytoin hydroxylation (CYP2C19) polymorphism. Ther Drug Monit. 2001;23:115-118.
-
(2001)
Ther Drug Monit
, vol.23
, pp. 115-118
-
-
Hadama, A.1
Ieiri, I.2
Morita, T.3
-
53
-
-
0034748878
-
Severe phenytoin intoxication in a subject homozygous for CYP2C9*3
-
Brandolese R, Scordo MG, Spina E, et al. Severe phenytoin intoxication in a subject homozygous for CYP2C9*3. Clin Pharmacol Ther. 2001;70:391-394.
-
(2001)
Clin Pharmacol Ther
, vol.70
, pp. 391-394
-
-
Brandolese, R.1
Scordo, M.G.2
Spina, E.3
-
54
-
-
0034042132
-
Genetic polymorphism of the CYP2C subfamily and excessive serum phenytoin concentration with central nervous system intoxication
-
Ninomiya H, Mamiya K, Matsuo S, et al. Genetic polymorphism of the CYP2C subfamily and excessive serum phenytoin concentration with central nervous system intoxication. Ther Drug Monit. 2000;22:230-232.
-
(2000)
Ther Drug Monit
, vol.22
, pp. 230-232
-
-
Ninomiya, H.1
Mamiya, K.2
Matsuo, S.3
-
55
-
-
0030858160
-
Genetic polymorphism of the CYP2C subfamily and its effect on the pharmacokinetics of phenytoin in Japanese patients with epilepsy
-
Odani A, Hashimoto Y, Otsuki Y, et al. Genetic polymorphism of the CYP2C subfamily and its effect on the pharmacokinetics of phenytoin in Japanese patients with epilepsy. Clin Pharmacol Ther. 1997;62:287-292.
-
(1997)
Clin Pharmacol Ther
, vol.62
, pp. 287-292
-
-
Odani, A.1
Hashimoto, Y.2
Otsuki, Y.3
-
56
-
-
34447312716
-
Idiosyncratic adverse reactions to antiepileptic drugs
-
Zaccara G, Franciotta D, Perucca E. Idiosyncratic adverse reactions to antiepileptic drugs. Epilepsia. 2007;48:1223-1244.
-
(2007)
Epilepsia
, vol.48
, pp. 1223-1244
-
-
Zaccara, G.1
Franciotta, D.2
Perucca, E.3
-
57
-
-
0024208020
-
Anticonvulsant hypersensitivity syndrome: In vitro assessment of risk
-
Shear NH, Spielberg SP. Anticonvulsant hypersensitivity syndrome: in vitro assessment of risk. J Clin Invest. 1988;82:1826-1832.
-
(1988)
J Clin Invest
, vol.82
, pp. 1826-1832
-
-
Shear, N.H.1
Spielberg, S.P.2
-
58
-
-
33645082244
-
Genetic susceptibility to carbamazepine-induced cutaneous adverse drug reactions
-
Hung SI, Chung WH, Jee SH, et al. Genetic susceptibility to carbamazepine-induced cutaneous adverse drug reactions. Pharmacogenetics and Genomics. 2006;16:297-306.
-
(2006)
Pharmacogenetics and Genomics
, vol.16
, pp. 297-306
-
-
Hung, S.I.1
Chung, W.H.2
Jee, S.H.3
-
59
-
-
1842784823
-
Medical genetics: A marker for Stevens-Johnson syndrome
-
Chung WH, Hung SI, Hong HS, et al. Medical genetics: a marker for Stevens-Johnson syndrome. Nature. 2004;428:486.
-
(2004)
Nature
, vol.428
, pp. 486
-
-
Chung, W.H.1
Hung, S.I.2
Hong, H.S.3
-
60
-
-
34248589506
-
Association between HLA-B*1502 allele and antiepileptic drug-induced cutaneous reactions in Han Chinese
-
Man CB, Kwan P, Baum L, et al. Association between HLA-B*1502 allele and antiepileptic drug-induced cutaneous reactions in Han Chinese. Epilepsia. 2007;48:1015-1018.
-
(2007)
Epilepsia
, vol.48
, pp. 1015-1018
-
-
Man, C.B.1
Kwan, P.2
Baum, L.3
-
61
-
-
33748987340
-
HLA-B locus in Caucasian patients with carbamazepine hypersensitivity
-
Alfirevic A, Jorgensen AL, Williamson PR, et al. HLA-B locus in Caucasian patients with carbamazepine hypersensitivity. Pharmacogenomics. 2006;7:813-818.
-
(2006)
Pharmacogenomics
, vol.7
, pp. 813-818
-
-
Alfirevic, A.1
Jorgensen, A.L.2
Williamson, P.R.3
-
62
-
-
33646934721
-
A marker for Stevens-Johnson syndrome: Ethnicity matters
-
Lonjou C, Thomas L, Borot N, et al. A marker for Stevens-Johnson syndrome: ethnicity matters. Pharmacogenomics J. 2006;6:265-268.
-
(2006)
Pharmacogenomics J
, vol.6
, pp. 265-268
-
-
Lonjou, C.1
Thomas, L.2
Borot, N.3
-
63
-
-
0033764534
-
Idiosyncratic reactions: New methods of identifying highrisk patients
-
Glauser TA. Idiosyncratic reactions: new methods of identifying highrisk patients. Epilepsia. 2000;41(Suppl 8):S16-29.
-
(2000)
Epilepsia
, vol.41
, Issue.SUPPL. 8
-
-
Glauser, T.A.1
-
64
-
-
20544475805
-
Drug resistance in epilepsy: Putative neurobiologic and clinical mechanisms
-
Schmidt D, Loscher W. Drug resistance in epilepsy: putative neurobiologic and clinical mechanisms. Epilepsia. 2005;46:858-877.
-
(2005)
Epilepsia
, vol.46
, pp. 858-877
-
-
Schmidt, D.1
Loscher, W.2
-
65
-
-
13244298981
-
Potential role of drug transporters in the pathogenesis of medically intractable epilepsy
-
Kwan P, Brodie MJ. Potential role of drug transporters in the pathogenesis of medically intractable epilepsy. Epilepsia. 2005;46:224-235.
-
(2005)
Epilepsia
, vol.46
, pp. 224-235
-
-
Kwan, P.1
Brodie, M.J.2
-
66
-
-
36949025921
-
Where is the evidence that P-glycoprotein limits brain uptake of antiepileptic drug and contributes to drug resistance in epilepsy?
-
In press
-
Anderson GD, Shen DD. Where is the evidence that P-glycoprotein limits brain uptake of antiepileptic drug and contributes to drug resistance in epilepsy? Epilepsia. In press.
-
Epilepsia
-
-
Anderson, G.D.1
Shen, D.D.2
-
67
-
-
0029836316
-
Role of P-glycoprotein in the blood-brain transport of colchicine and vinblastine
-
Drion N, Lemaire M, Lefauconnier JM, et al. Role of P-glycoprotein in the blood-brain transport of colchicine and vinblastine. J Neurochem. 1996;67:1688-1693.
-
(1996)
J Neurochem
, vol.67
, pp. 1688-1693
-
-
Drion, N.1
Lemaire, M.2
Lefauconnier, J.M.3
-
68
-
-
0035167174
-
In vivo evidence for P-glycoprotein-mediated transport of phenytoin at the blood-brain barrier of rats
-
Potschka H, Loscher W. In vivo evidence for P-glycoprotein-mediated transport of phenytoin at the blood-brain barrier of rats. Epilepsia. 2001;42:1231-1240.
-
(2001)
Epilepsia
, vol.42
, pp. 1231-1240
-
-
Potschka, H.1
Loscher, W.2
-
69
-
-
0035900333
-
P-glycoprotein and multidrug resistance-associated protein are involved in the regulation of extracellular levels of the major antiepileptic drug carbamazepine in the brain
-
Potschka H, Fedrowitz M, Loscher W. P-glycoprotein and multidrug resistance-associated protein are involved in the regulation of extracellular levels of the major antiepileptic drug carbamazepine in the brain. Neuroreport. 2001;12:3557-3560.
-
(2001)
Neuroreport
, vol.12
, pp. 3557-3560
-
-
Potschka, H.1
Fedrowitz, M.2
Loscher, W.3
-
70
-
-
0037178642
-
P-Glycoprotein-mediated efflux of phenobarbital, lamotrigine, and felbamate at the blood-brain barrier: Evidence from microdialysis experiments in rats
-
Potschka H, Fedrowitz M, Loscher W. P-Glycoprotein-mediated efflux of phenobarbital, lamotrigine, and felbamate at the blood-brain barrier: evidence from microdialysis experiments in rats. Neurosci Lett. 2002;327:173-176.
-
(2002)
Neurosci Lett
, vol.327
, pp. 173-176
-
-
Potschka, H.1
Fedrowitz, M.2
Loscher, W.3
-
71
-
-
0842282552
-
Nonlinear oral pharmacokinetics of the alpha-antagonist 4-amino-5-(4-fluorophenyl)-6,7-dimethoxy-2-[4- (morpholinocarbonyl)-perhydr o-1,4-diazepin-1-yl]quinoline in humans: Use of preclinical data to rationalize clinical observations
-
Harrison A, Betts A, Fenner K, et al. Nonlinear oral pharmacokinetics of the alpha-antagonist 4-amino-5-(4-fluorophenyl)-6,7-dimethoxy-2-[4- (morpholinocarbonyl)-perhydr o-1,4-diazepin-1-yl]quinoline in humans: use of preclinical data to rationalize clinical observations. Drug Metab Dispos. 2004;32:197-204.
-
(2004)
Drug Metab Dispos
, vol.32
, pp. 197-204
-
-
Harrison, A.1
Betts, A.2
Fenner, K.3
-
72
-
-
0021264019
-
Distribution of phenobarbital in serum, brain and other organs from pediatric patients
-
Onishi S, Ohki Y, Nishimura Y, et al. Distribution of phenobarbital in serum, brain and other organs from pediatric patients. Dev Pharmacol Ther. 1984;7:153-159.
-
(1984)
Dev Pharmacol Ther
, vol.7
, pp. 153-159
-
-
Onishi, S.1
Ohki, Y.2
Nishimura, Y.3
-
73
-
-
33746302765
-
Human epilepsies: Interaction of genetic and acquired factors
-
Berkovic SF, Mulley JC, Scheffer IE, et al. Human epilepsies: interaction of genetic and acquired factors. Trends Neurosci. 2006;29:391-397.
-
(2006)
Trends Neurosci
, vol.29
, pp. 391-397
-
-
Berkovic, S.F.1
Mulley, J.C.2
Scheffer, I.E.3
-
75
-
-
33750594715
-
Clinical spectrum of mutations in SCN1A gene: Severe myoclonic epilepsy in infancy and related epilepsies
-
Fujiwara T. Clinical spectrum of mutations in SCN1A gene: severe myoclonic epilepsy in infancy and related epilepsies. Epilepsy Res. 2006;70(Suppl 1):S223-230.
-
(2006)
Epilepsy Res
, vol.70
, Issue.SUPPL. 1
-
-
Fujiwara, T.1
-
76
-
-
33748115786
-
Reduced sodium current in GABAergic interneurons in a mouse model of severe myoclonic epilepsy in infancy
-
Yu FH, Mantegazza M, Westenbroek RE, et al. Reduced sodium current in GABAergic interneurons in a mouse model of severe myoclonic epilepsy in infancy. Nat Neurosci. 2006;9:1142-1149.
-
(2006)
Nat Neurosci
, vol.9
, pp. 1142-1149
-
-
Yu, F.H.1
Mantegazza, M.2
Westenbroek, R.E.3
-
77
-
-
35348904490
-
Reduced sodium current in Purkinje neurons from Nav1.1 mutant mice: Implications for ataxia in severe myoclonic epilepsy in infancy
-
Kalume F, Yu FH, Westenbroek RE, et al. Reduced sodium current in Purkinje neurons from Nav1.1 mutant mice: implications for ataxia in severe myoclonic epilepsy in infancy. J Neurosci. 2007;27:11065-11074.
-
(2007)
J Neurosci
, vol.27
, pp. 11065-11074
-
-
Kalume, F.1
Yu, F.H.2
Westenbroek, R.E.3
-
78
-
-
0032730181
-
The pharmacologic basis of antiepileptic drug action
-
Rho JM, Sankar R. The pharmacologic basis of antiepileptic drug action. Epilepsia. 1999;40:1471-1483.
-
(1999)
Epilepsia
, vol.40
, pp. 1471-1483
-
-
Rho, J.M.1
Sankar, R.2
-
79
-
-
0036227290
-
Lamotrigine reduces spontaneous and evoked GABAA receptor-mediated synaptic transmission in the basolateral amygdala: Implications for its effects in seizure and affective disorders
-
Braga MF, Aroniadou-Anderjaska V, Post RM, et al. Lamotrigine reduces spontaneous and evoked GABAA receptor-mediated synaptic transmission in the basolateral amygdala: implications for its effects in seizure and affective disorders. Neuropharmacology. 2002;42:522-529.
-
(2002)
Neuropharmacology
, vol.42
, pp. 522-529
-
-
Braga, M.F.1
Aroniadou-Anderjaska, V.2
Post, R.M.3
-
80
-
-
0036337572
-
How mutations in the nAChRs can cause ADNFLE epilepsy
-
Bertrand D, Picard F, Le Hellard S, et al. How mutations in the nAChRs can cause ADNFLE epilepsy. Epilepsia. 2002;43(Suppl 5):112-122.
-
(2002)
Epilepsia
, vol.43
, Issue.SUPPL. 5
, pp. 112-122
-
-
Bertrand, D.1
Picard, F.2
Le Hellard, S.3
-
81
-
-
34548688700
-
The role of the nicotinic acetylcholine receptors in sleep-related epilepsy
-
Marini C, Guerrini R. The role of the nicotinic acetylcholine receptors in sleep-related epilepsy. Biochem Pharmacol. 2007;74:1308-1314.
-
(2007)
Biochem Pharmacol
, vol.74
, pp. 1308-1314
-
-
Marini, C.1
Guerrini, R.2
-
82
-
-
0036022630
-
Molecular modelling of the interactions of carbamazepine and a nicotinic receptor involved in the autosomal dominant nocturnal frontal lobe epilepsy
-
Ortells MO, Barrantes GE. Molecular modelling of the interactions of carbamazepine and a nicotinic receptor involved in the autosomal dominant nocturnal frontal lobe epilepsy. Br J Pharmacol. 2002;136:883-895.
-
(2002)
Br J Pharmacol
, vol.136
, pp. 883-895
-
-
Ortells, M.O.1
Barrantes, G.E.2
-
83
-
-
14944384270
-
Genetics of idiopathic epilepsies
-
Hirose S, Mitsudome A, Okada M, et al. Genetics of idiopathic epilepsies. Epilepsia. 2005;46(suppl 1):38-43.
-
(2005)
Epilepsia
, vol.46
, Issue.SUPPL. 1
, pp. 38-43
-
-
Hirose, S.1
Mitsudome, A.2
Okada, M.3
-
84
-
-
0033916576
-
Modulation of KCNQ2/3 potassium channels by the novel anticonvulsant retigabine
-
Main MJ, Cryan JE, Dupere JR, et al. Modulation of KCNQ2/3 potassium channels by the novel anticonvulsant retigabine. Mol Pharmacol. 2000;58:253-262.
-
(2000)
Mol Pharmacol
, vol.58
, pp. 253-262
-
-
Main, M.J.1
Cryan, J.E.2
Dupere, J.R.3
-
85
-
-
0033862433
-
Retigabine, a novel anti-convulsant, enhances activation of KCNQ2/Q3 potassium channels
-
Wickenden AD, Yu W, Zou A, et al. Retigabine, a novel anti-convulsant, enhances activation of KCNQ2/Q3 potassium channels. Mol Pharmacol. 2000;58:591-600.
-
(2000)
Mol Pharmacol
, vol.58
, pp. 591-600
-
-
Wickenden, A.D.1
Yu, W.2
Zou, A.3
-
87
-
-
0038653828
-
-
13th ed. Whitehouse Station, NJ: Merck & Co, Inc;
-
Budavari S. The Merck Index, 13th ed. Whitehouse Station, NJ: Merck & Co, Inc; 1996.
-
(1996)
The Merck Index
-
-
Budavari, S.1
-
88
-
-
42049100573
-
Benzodiazepines: Chemistry, biotransformation and pharmacokinetics
-
Levy RH, Mattson RH, Meldrum BS, et al, eds, 5th ed. Philadelphia: Lippincott Williams & Wilkins;
-
Anderson GD, Miller JW. Benzodiazepines: chemistry, biotransformation and pharmacokinetics. In: Levy RH, Mattson RH, Meldrum BS, et al, eds. Antiepileptic Drugs, 5th ed. Philadelphia: Lippincott Williams & Wilkins; 2002:187-205.
-
(2002)
Antiepileptic Drugs
, pp. 187-205
-
-
Anderson, G.D.1
Miller, J.W.2
-
89
-
-
42049101224
-
Ethosuximide: Chemistry, biotransformation, pharmacokinetics and drug interactions
-
Levy RH, Mattson RH, Meldrun BS, et al, eds, 5th ed. Philadelphia: Lippincott Williams & Wilkins;
-
Pisani F, Perucca E, Bialer M. Ethosuximide: chemistry, biotransformation, pharmacokinetics and drug interactions. In: Levy RH, Mattson RH, Meldrun BS, et al, eds. Antiepileptic Drugs, 5th ed. Philadelphia: Lippincott Williams & Wilkins; 2002:646-651.
-
(2002)
Antiepileptic Drugs
, pp. 646-651
-
-
Pisani, F.1
Perucca, E.2
Bialer, M.3
-
90
-
-
0002668756
-
Felbamate. Chemistry and biotransformation
-
Levy RH, Mattson RH, Meldrum BS, eds, 4th ed. New York: Raven Press;
-
Kucharczyk N. Felbamate. Chemistry and biotransformation. In: Levy RH, Mattson RH, Meldrum BS, eds. Antiepileptic Drugs, 4th ed. New York: Raven Press; 1995:799-806.
-
(1995)
Antiepileptic Drugs
, pp. 799-806
-
-
Kucharczyk, N.1
-
91
-
-
2642557099
-
Gabapentin: Chemistry, biotransformation, pharmacokinetics, and interactions
-
Levy RH, Mattson RH, Meldrum BS, et al, eds, 5th ed. Philadelphia: Lippencott Williams & Wilkins;
-
Vajda FJE. Gabapentin: chemistry, biotransformation, pharmacokinetics, and interactions. In: Levy RH, Mattson RH, Meldrum BS, et al, eds. Antiepileptic Drugs, 5th ed. Philadelphia: Lippencott Williams & Wilkins; 2002:335-343.
-
(2002)
Antiepileptic Drugs
, pp. 335-343
-
-
Vajda, F.J.E.1
-
92
-
-
0002383849
-
Lamotrigine: Chemistry and biotransformation
-
Levy RH, Mattson RH, Meldrun BS, eds, 5th ed. New York: Raven Press;
-
Dickins M, Sawyer DA, Moreley TJ, et al. Lamotrigine: chemistry and biotransformation. In: Levy RH, Mattson RH, Meldrun BS, eds. Antiepileptic Drugs, 5th ed. New York: Raven Press; 1995:871-875.
-
(1995)
Antiepileptic Drugs
, pp. 871-875
-
-
Dickins, M.1
Sawyer, D.A.2
Moreley, T.J.3
-
93
-
-
2142831652
-
Levetiracetam: Chemistry, biotransformation, pharmacokinetics and drug interactions
-
Levy RH, Mattson RH, Meldrum BS, et al, eds, 5th ed. Philadelphia: Lippincott Williams & Wilkins;
-
Patsalos PN. Levetiracetam: chemistry, biotransformation, pharmacokinetics and drug interactions. In: Levy RH, Mattson RH, Meldrum BS, et al, eds. Antiepileptic Drugs, 5th ed. Philadelphia: Lippincott Williams & Wilkins; 2002:428-432.
-
(2002)
Antiepileptic Drugs
, pp. 428-432
-
-
Patsalos, P.N.1
-
94
-
-
0141516469
-
Oxcarbazepine. Chemistry, biotransformation, and pharmacokinetics
-
Levy RH, Mattson RH, Meldrum BS, et al, eds, 5th ed. Philadelphia: Lippincott Williams & Wilkins;
-
Bialer M. Oxcarbazepine. Chemistry, biotransformation, and pharmacokinetics. In: Levy RH, Mattson RH, Meldrum BS, et al, eds. Antiepileptic Drugs, 5th ed. Philadelphia: Lippincott Williams & Wilkins; 2002:459-465.
-
(2002)
Antiepileptic Drugs
, pp. 459-465
-
-
Bialer, M.1
-
95
-
-
42049115924
-
-
Levy RH, Mattson RH, Meldrum BS, et al, eds, Philadelphia: Lippincott Williams & Wilkins;
-
Ben-Menachem E. Pregablin. In: Levy RH, Mattson RH, Meldrum BS, et al, eds. Antiepileptic Drugs. Philadelphia: Lippincott Williams & Wilkins; 2002:901-905.
-
(2002)
Antiepileptic Drugs
, pp. 901-905
-
-
Pregablin, B.-M.E.1
-
96
-
-
42049097037
-
Primidone
-
Levy RH, Mattson RH, Meldrum BS, et al, eds, 5th ed. Philadelphia: Lippincott Williams & Wilkins;
-
Fincham RW. Primidone. In: Levy RH, Mattson RH, Meldrum BS, et al, eds. Antiepileptic Drugs, 5th ed. Philadelphia: Lippincott Williams & Wilkins; 2002:621-635.
-
(2002)
Antiepileptic Drugs
, pp. 621-635
-
-
Fincham, R.W.1
-
97
-
-
18444403961
-
Tiagabine. Chemistry, biotransformation, and pharmacokinetics
-
Levy RH, Mattson RH, Meldrum BS, et al, eds, Philadelphia: Lippincott Williams & Wilkins;
-
Sommerville KW, Collins SD. Tiagabine. Chemistry, biotransformation, and pharmacokinetics. In: Levy RH, Mattson RH, Meldrum BS, et al, eds. Antipileptic Drugs. Philadelphia: Lippincott Williams & Wilkins; 2002:681-690.
-
(2002)
Antipileptic Drugs
, pp. 681-690
-
-
Sommerville, K.W.1
Collins, S.D.2
-
98
-
-
0038436191
-
Topiramate: Chemistry, biotransformation and pharmacokinetics
-
Levy RH, Mattson RH, Meldrum BS, et al, eds, 5th ed. Philadelphia: Lippincott Williams & Wilkins;
-
Doose DR, Streeter AJ. Topiramate: chemistry, biotransformation and pharmacokinetics. In: Levy RH, Mattson RH, Meldrum BS, et al, eds. Antiepileptic Drugs, 5th ed. Philadelphia: Lippincott Williams & Wilkins; 2002:727-734.
-
(2002)
Antiepileptic Drugs
, pp. 727-734
-
-
Doose, D.R.1
Streeter, A.J.2
-
99
-
-
1442270464
-
Zonisamide: Chemistry, biotransformation and pharmacokinetics
-
Levy RH, Mattson RH, Meldrum BS, et al, eds, 5th ed. Philadelphia: Lippincott Williams & Wilkins;
-
Shah J, Shellenberger K, Canafax DM. Zonisamide: chemistry, biotransformation and pharmacokinetics. In: Levy RH, Mattson RH, Meldrum BS, et al, eds. Antiepileptic Drugs, 5th ed. Philadelphia: Lippincott Williams & Wilkins; 2002:873-879.
-
(2002)
Antiepileptic Drugs
, pp. 873-879
-
-
Shah, J.1
Shellenberger, K.2
Canafax, D.M.3
-
100
-
-
0028229150
-
Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs
-
Schinkel AH, Smit JJ, van Tellingen O, et al. Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs. Cell. 1994;77:491-502.
-
(1994)
Cell
, vol.77
, pp. 491-502
-
-
Schinkel, A.H.1
Smit, J.J.2
van Tellingen, O.3
-
101
-
-
0028825399
-
Absence of the mdr1a P-glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A
-
Schinkel AH, Wagenaar E, van Deemter L, et al. Absence of the mdr1a P-glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A. J Clin Invest. 1995;96:1698-1705.
-
(1995)
J Clin Invest
, vol.96
, pp. 1698-1705
-
-
Schinkel, A.H.1
Wagenaar, E.2
van Deemter, L.3
-
102
-
-
0036816334
-
P-glycoprotein-mediated efflux of antiepileptic drugs: Preliminary studies in mdr1a knockout mice
-
Sills GJ, Kwan P, Butler E, et al. P-glycoprotein-mediated efflux of antiepileptic drugs: preliminary studies in mdr1a knockout mice. Epilepsy Behav. 2002;3:427-432.
-
(2002)
Epilepsy Behav
, vol.3
, pp. 427-432
-
-
Sills, G.J.1
Kwan, P.2
Butler, E.3
|